Effects of polyamines on the muscarinic receptor-operated cation current in guinea-pig ileal smooth muscle myocytes

British Journal of Pharmacology

Volumn 143, Issue 8, 2004, Pages 968-975

  Tsvilovskyy, Volodymyr V ^a   Zholos, Alexander V ^a,c   Bolton, Thomas B ^b  

^a BOGOMOLETZ INSTITUTE OF PHYSIOLOGY   (Ukraine)

^b ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

^c Université des Sciences et Technologies de Lille   (France)

Author keywords

Carbachol; Cation current; Gastrointestinal smooth muscle; GTP S; Muscarinic receptor; Polyamines; Putrescine; Spermine

Indexed keywords

CARBACHOL; CATION CHANNEL; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); MUSCARINIC RECEPTOR; POLYAMINE; PUTRESCINE; SPERMINE;

ANIMAL CELL; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; GASTROINTESTINAL TRACT; GUINEA PIG; ILEUM; INTESTINE MUSCLE; ION CURRENT; MEMBRANE CONDUCTANCE; MEMBRANE DEPOLARIZATION; MUSCLE CELL; NONHUMAN; PRIORITY JOURNAL; SMOOTH MUSCLE;

ANIMALS; BIOGENIC POLYAMINES; CATIONS; DOSE-RESPONSE RELATIONSHIP, DRUG; GUINEA PIGS; ILEUM; MALE; MUSCLE, SMOOTH; MYOCYTES, SMOOTH MUSCLE; RECEPTORS, MUSCARINIC;

EID: 11244339697     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0706010     Document Type: Article

References (33)

1. ARANEDA, R.C., LAN, J.Y., ZHENG, X., ZUKIN, R.S. & BENNETT, M.V. (1999). Spermine and arcaine block and permeate N-methyl-D-aspartate receptor channels. Biophys. J., 76, 2899-2911.
2. AZIZ, S.M., YATIN, M., WORTHEN, D.R., LIPKE, D.W. & CROOKS, P.A. (1998). A novel technique for visualizing the intracellular localization and distribution of transported polyamines in cultured pulmonary artery smooth muscle cells. J. Pharm. Biomed. Anal., 17, 307-320.
3. 3 muscarinic receptors. Life Sci., 60, 1121-1128.
4. GOMEZ, M. & HELLSTRAND, P. (1995). Effects of polyamines on voltage-activated calcium channels in guinea-pig intestinal smooth muscle. Pflugers Arch., 430, 501-507.
5. 2+ channel activity in guinea-pig intestinal smooth muscle. Pflugers Arch., 438, 445-451.
6. 2+ indicators with greatly improved fluorescence properties. J. Biol. Chem., 260, 3440-3450.
7. GUO, D. & LU, Z. (2000). Mechanism of cGMP-gated channel block by intracellular polyamines. J. Gen. Physiol., 115, 783-797.
8. HAGHIGHI, A.P. & COOPER, E. (1998). Neuronal nicotinic acetylcho-line receptors are blocked by intracellular spermine in a voltage-dependent manner. J. Neurosci., 18, 4050-4062.
9. HUANG, C.J. & MOCZYDLOWSKI, E. (2001). Cytoplasmic polyamines as permeant blockers and modulators of the voltage-gated sodium channel. Biophys. J., 80, 1262-1279.
10. IGARASHI, K. & KASHIWAGI, K. (2000). Polyamines: mysterious modulators of cellular functions. Biochem. Biophys. Res. Commun., 271, 559-564.
11. JÄNNE, J., ALHONEN, L., PIETILÄ, M. & KEINÄNEN, T.A. (2004). Genetic approaches to the cellular functions of polyamines in mammals. Eur. J. Biochem., 271, 877-894.
12. LEE, Y.M., KIM, B.J., KIM, H.J., YANG, D.K., ZHU, M.H., LEE, K.P., SO, I. & KIM, K.W. (2003). TRPC5 as a candidate for the nonselective cation channel activated by muscarinic stimulation in murine stomach. Am. J. Physiol., 284, G604-G616.
13. LOPATIN, A.N., MAKHINA, E.N. & NICHOLS, C.G. (1994). Potassium channel block by cytoplasmic polyamines as the mechanism of intrinsic rectification. Nature, 372, 366-369.
14. + channels. Annu. Rev. Physiol., 66, 103-129.
15. LU, Z. & DING, L. (1999). Blockade of a retinal cGMP-gated channel by polyamines. J. Gen. Physiol., 113, 35-43.
16. NILIUS, B. (2003). Calcium-impermeable monovalent cation channels: a TRP connection? Br. J. Pharmacol., 138, 5-7.
17. 2+-activated cation channel TRPM4b. Pflugers Arch., 448, 70-75.
18. 2+ channel and phosphatase activities by polyamines in intestinal and vascular smooth muscle - implications for cellular growth and contractility. Acta Physiol. Scand., 176, 33-41.
19. NILSSON, B.O. & HELLSTRAND, P. (1993). Effects of polyamines on intracellular calcium and mechanical activity in smooth muscle of guinea-pig taenia coli. Acta Physiol. Scand., 148, 37-43.
20. ONODERA, K., UNEMOTO, T., MIYAKI, K. & HAYASHI, M. (1968). Pharmacological studies on polyamines. I. Relaxing effect of spermine and spermidine on smooth muscle of guinea pig ileum contracted by 5-hydroxytryptamine and nicotine. Arch. Int. Pharmacodyn. Ther., 174, 491-494.
21. OSBORNE, D.L. & SEIDEL, E.R. (1990). Gastrointestinal luminal polyamines: cellular accumulation and enterohepatic circulation. Am. J. Physiol., 258, G576-G584.
22. PUSCH, M. & NEHER, E. (1988). Rates of diffusional exchange between small cells and a measuring patch pipette. Pflugers Arch., 411, 204-211.
23. 2+ sensitivity in permeabilized smooth muscle of guinea pig ileum. Am. J. Physiol., 266, C1754-C1763.
24. WALLACE, H.M., FRASER, A.V. & HUGHES, A. (2003). A perspective of polyamine metabolism. Biochem. J., 376, 1-14.
25. WATANABE, S., KUSAMA, E., KOBAYASHI, H. & IGARASHI, K. (1991). Estimation of polyamine binding to macromolecules and ATP in bovine lymphocytes and rat liver. J. Biol. Chem., 266, 20803-20809.
26. WILLIAMS, K. (1997). Interactions of polyamines with ion channels. Biochem. J., 325, 289-297.
27. WOJCIKIEWICZ, R.J. & FAIN, J.N. (1988). Polyamines inhibit phospholipase C-catalysed polyphosphoinositide hydrolysis. Studies with permeabilized GH3 cells. Biochem. J., 255, 1015-1021.
28. 2+ and inhibition by polycations. Br. J. Pharmacol., 138, 234-244.
29. ZHOLOS, A.V. & BOLTON, T.B. (1995). Effects of divalent cations on muscarinic receptor cationic current in smooth muscle from guinea-pig small intestine. J. Physiol., 486, 67-82.
30. ZHOLOS, A.V. & BOLTON, T.B. (1996). A novel GTP-dependent mechanism of ileal muscarinic metabotropic channel desensitization. Br. J. Pharmacol., 119, 997-1012.
31. ZHOLOS, A.V., TSVILOVSKYY, V.V. & BOLTON, T.B. (2003). Muscarinic cholinergic excitation of smooth muscle: signal transduction and single cationic channel properties. Neurophysiology, 35, 283-301.
32. 3 or DAG, dependent activation of the muscarinic receptor-operated cation current in guinea-pig ileal smooth muscle cells. Br. J. Pharmacol., 141, 23-36.
33. ZHOLOS, A.V., ZHOLOS, A.A. & BOLTON, T.B. (2004b). G-protein-gated TRP-like cationic channel activated by muscarinic receptors: effect of potential on single-channel gating. J. Gen. Physiol., 123, 581-598.