Regulation of Ca2+ channel and phosphatase activities by polyamines in intestinal and vascular smooth muscle -implications for cellular growth and contractility

Acta Physiologica Scandinavica

Volumn 176, Issue 1, 2002, Pages 33-41

  Nilsson, B O ^a   Gomez, M F ^a   Sward K ^a   Hellstrand, P ^a  

^a LUND UNIVERSITY   (Sweden)

Author keywords

Calcium; Ion channels; Polyamines; Protein phosphatases; Putrescine; Smooth muscle; Spermidine; Spermine

Indexed keywords

CALCIUM CHANNEL; CALCIUM ION; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATASE; POLYAMINE; POTASSIUM; POTASSIUM CHANNEL; CALCIUM; PHOSPHOPROTEIN PHOSPHATASE; PUTRESCINE; SPERMIDINE; SPERMINE;

ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL GROWTH; CYTOSKELETON; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; INTESTINE MUSCLE; MUSCLE FIBER CONTRACTION; NONHUMAN; POLYAMINE METABOLISM; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SMOOTH MUSCLE; SMOOTH MUSCLE CONTRACTILITY; TISSUE DISTRIBUTION; VASCULAR SMOOTH MUSCLE; DRUG ANTAGONISM; DRUG EFFECT; HUMAN; METABOLISM; MUSCLE CONTRACTION; PHYSIOLOGY; REVIEW;

CALCIUM; CALCIUM CHANNELS; CYTOSKELETON; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASES; MUSCLE CONTRACTION; MUSCLE, SMOOTH; PHOSPHOPROTEIN PHOSPHATASE; POLYAMINES; POTASSIUM CHANNELS; PUTRESCINE; SPERMIDINE; SPERMINE;

EID: 0035982015     PISSN: 00016772     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-201X.2002.01013.x     Document Type: Article

References (63)

1. The control of phosphatase-1 by targetting subunits. The major myosin phosphatase in avian smooth muscle is a novel form of protein phosphatase-1
2. Tumor attenuation by combined heparan sulfate and polyamine depletion
3. Proteoglycan involvement in polyamine uptake
4. + channels in RBL-1 cells
5. Protein phosphatase 1-targeted in many directions
6. Relaxing effect of spermine and spermidine on intact and glycerol-treated muscle
7. + channels
8. P44/42 mitogen-activated protein kinase is involved in the expression of ornithine decarboxylase in leukaemia L1210 cells
9. Ornithine decarboxylase and S-adenosylmethionine decarboxylase expression during the cell cycle of Chinese hamster ovary cells
10. Effects of polyamines on voltage-activated calcium channels in guinea-pig intestinal smooth muscle
11. 2+ channel activity in guinea-pig intestinal smooth muscle
12. 2+ sensitization of smooth muscle
13. 2+ sensitivity of tension and increase rates of activation in skinned cardiac myocytes
14. Myosin light chain phosphatase: Subunit composition, interactions and regulation
15. Inhibitory action of spermine on the contraction of rat uterus
16. Protein phosphatases: Properties and role in cellular regulation
17. 2+ transport
18. 2+ transport by endoplasmic reticulum and mitochondria in permeabilized pancreatic islets
19. Potassium channel block by cytoplasmic polyamines as the mechanism for intrinsic rectification
20. Cooperativity between the polyamine pathway and HER-2neu in transformation of human mammary epithelial cells in culture: Role of the MAPK pathway
21. Effects of polyamines on the mechanical and electrical activities of the isolated circular muscle of rat uterus
22. Polyamine deficiency alters the EGF receptor distribution and signaling effectiveness in IEC-6 cells
23. Catalytic irreversible inhibition of mammalian ornithine decarboxylase (E.C. 4.1.1.17) by substrate and product analogues
24. Ornithine decarboxylase transformation of NIH/3T3 cells is mediated by altered epidermal growth factor receptor activity
25. Rho effectors and reorganization of actin cytoskeleton
26. Differential actions of exogenous and intracellular spermine on contractile activity in smooth muscle of rat portal vein
27. Effects of polyamines on intracellular calcium and mechanical activity in smooth muscle of guinea-pig taenia coli
28. Reduced tyrosine phosphorylation in polyamine-starved cells
29. Polyamine-induced actin polymerization
30. Role of Rho proteins in carbachol-induced contractions in intact and permeabilized guinea-pig intestinal smooth muscle
31. Polyamine-dependent alterations in the structure of microfilaments, Golgi apparatus, endoplasmic reticulum, and proteoglycan synthesis in BHK cells
32. Purification and characterization of a multisubunit phosphatase from turkey gizzard smooth muscle
33. 2+-dependent phosphatase from turkey gizzard smooth muscle
34. Purification and characterization of a smooth muscle myosin phosphatase from turkey gizzards
35. Recent advances in the biochemistry of polyamines in eukaryotes
36. Polyamine metabolism and its importance in neoplastic growth and as a target for chemotherapy
37. 2+-RhoA signaling pathway required for polyamine-dependent intestinal epithelial cell migration
38. CGP 48664, a new s-adenosylmethionine decarboxylase inhibitor with broad spectrum antiproliferative and antitumor activity
39. Effect of spermine on mitochondrial matrix calcium in relation to its enhancement of mitochondrial calcium uptake
40. Polyamine modulation of mitochondrial calcium transport I. Stimulatory and inhibitory effects of aliphatic polyamines, aminoglucosides and other polyamine analogues on mitochondrial calcium uptake
41. Polyamine modulation of mitochondrial calcium transport II. Inhibition of mitochondrial permeability transition by aliphatic polyamines but not by aminoglucosides
42. Influence of polyamines on membrane functions
43. Interactions of polyamines with neuronal ion channels
44. Polyamine catabolism and elimination by the vertebrate organism
45. Polyamine transport in mammalian cells
46. Depletion of intracellular polyamines relieves inward rectification of potassium channels
47. 2+, inositol phosphate generation, and phorbol ester sensitivity
48. Polyamines regulate serine/threonine protein phosphatases in insulin-secreting cells
49. Inward rectification of the large conductance potassium channel in smooth muscle cells from rabbit pulmonary artery
50. 4-Amidinohydrazone: A new potent and selective inhibitor of S-adenosylmethionin decarboxylase
51. 2+ sensitization of myosin phosphorylation and force in guinea-pig ileum
52. 2+ sensitivity in permeabilized smooth muscle of guinea-pig ileum
53. Inhibition of polyamine synthesis influences contractility of intestinal smooth muscle in culture
54. 20 phosphorylation and force in smooth muscle
55. Interaction of spermine with polyphosphoinositides containing liposomes and myoinositol 1,4,5 triphosphate
56. Turkey gizzard smooth muscle myosin phosphatase III is a novel protein phosphatase
57. Estimation of polyamine binding to macromolecules and ATP in bovine lymphocytes and rat liver
58. Interactions of polyamines with ion channels
59. Activation of p42/44 and p38 mitogen-activated protein kinases by extracellular calcium-sensing receptor agonists induces mitogenic responses in the mouse osteoblastic MC3T3-E1 cell line
60. Polyamine enhancement of the synthesis of adenylate cyclase at the translational level and the consequential stimulation of the synthesis of the RNA polymerase sigma 28 subunit
61. Putrescine does not support the migration and growth of IEC-6 cells