Renal elimination of a novel and potent αvβ 3 integrin antagonist in animals

Xenobiotica

Volumn 34, Issue 11-12, 2004, Pages 1059-1074

  Prueksaritanont, T ^a   Hochman, J H ^a   Meng, Y ^a   Pudvah, N T ^a   Barrish, A ^a   Ma, B ^a   Yamazaki, M ^a   Fernandez Metzler, C ^a   Lin, J H ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 [2 OXO 3 [3 (5,6,7,8 TETRAHYDRO[1,8]NAPHTHYRIDIN 2 YL)PROPYL]IMIDAZOLIN 1 YL](6 METHOXYPYRIDIN 3 YL)PROPIONIC ACID; 4 AMINOHIPPURIC ACID; ALPHA5BETA3 INTEGIN ANTAGONIST; CIMETIDINE; INTEGRIN; PENICILLIN G; PLASMA PROTEIN; PROBENECID; QUINIDINE; UNCLASSIFIED DRUG; VITRONECTIN RECEPTOR;

ANIMAL EXPERIMENT; ARTICLE; CELL STRAIN CACO 2; DRUG CLEARANCE; DRUG ELIMINATION; DRUG METABOLISM; DRUG PROTEIN BINDING; FEMALE; GLOMERULUS FILTRATION RATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; KIDNEY METABOLISM; KIDNEY TUBULE FUNCTION; MALE; MASS SPECTROMETRY; NONHUMAN; NUCLEOTIDE SEQUENCE; RAT; RHESUS MONKEY; URINARY EXCRETION;

ANIMALS; FEMALE; IMIDAZOLES; INTEGRIN ALPHAVBETA3; KIDNEY; MACACA MULATTA; MALE; METABOLIC CLEARANCE RATE; NAPHTHYRIDINES; RATS; RATS, SPRAGUE-DAWLEY; SPECIES SPECIFICITY;

ANIMALIA; GLOMERULUS; MACACA MULATTA;

EID: 11244309788     PISSN: 00498254     EISSN: None     Source Type: Journal    
DOI: 10.1080/00498250400015277     Document Type: Article

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