Expression of estrogen receptor β messenger RNA variant in breast cancer

Cancer Research

Volumn 58, Issue 2, 1998, Pages 210-214

  Vladusic, Esteban A ^a   Hornby, Ann E ^a   Guerra Vladusic, Fabiana K ^a   Lupu, Ruth ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ESTRADIOL; ESTROGEN RECEPTOR; MESSENGER RNA;

ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CONTROLLED STUDY; HUMAN; HUMAN CELL; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; RNA ANALYSIS;

BASE SEQUENCE; BREAST; BREAST NEOPLASMS; DNA PRIMERS; ESTROGEN RECEPTOR BETA; FEMALE; GENE DELETION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MOLECULAR SEQUENCE DATA; ORGANOIDS; POLYMERASE CHAIN REACTION; RECEPTORS, ESTROGEN; RNA, MESSENGER; RNA, NEOPLASM; TUMOR CELLS, CULTURED;

EID: 0031975052     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Kuiper, G. G. J. M., Enmark, E., Pelto-Huikko, M., Nilsson, S., and Gustafsson, J-A. Cloning of a novel estrogen receptor expressed in rat prostate and ovary. Proc. Natl. Acad. Sci. USA, 93: 5925-5930, 1996.
2. Tremblay, G. B., Tremblay, A., Copeland, N. G., Gilbert, D. J., Jenkins, N. A., Labrie, F., and Giguere, V. Cloning, chromosomal localization, and functional analysis of the murine estrogen receptor β. Mol. Endocrinol., 11: 353-365, 1997.
3. Mosselman, S., Polman, J., and Dijkema, R. ER β: identification and characterization of a novel human estrogen receptor. FEBS Lett., 392: 49-53, 1996.
4. Kuiper, G. G. J. M., Carlsson, B., Grandien, K., Enmark, E., Haggblad, J., Nilsson, S., and Gustafsson, J-A. Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors a and β. Endocrinology, 138: 863-870, 1997.
5. Vladusic, E. A., Hornby, A. E., Guerra-Vladusic, F. K., and Lupu, R. Expression of ERβ in breast cancer cells: does it play an important role? Proc. Am. Assoc. Cancer Res., 38: 297, 1997.
6. Topper, J., and Freedman, C. Multiple hormone interactions in the developmental biology of the mammary gland. Physiol. Rev., 60: 1049-1060, 1980.
7. Vorherr, H. Morphology, physiology and lactation. In: The Breast, pp. 1-19., 1974.
8. McGuire, W. L., Carbone, P. P., and Vollmer, E. P. (eds.). Estrogen Receptors in Human Breast Cancer. New York: Raven Press, 1975.
9. Dickson, R. B., and Lippman, M. E. Cellular and molecular biology. In: M. E. Lippman and R. B. Dickson (eds.), Breast Cancer, pp. 119-165. 1988.
10. Forman, B. M., and Samuels, H. H. Dimerization among nuclear hormone receptors. New Biol., 2: 587-594, 1990.
11. Lippman, M. E. An assessment of current achievements in the systemic management of breast cancer. Breast Cancer Res. Treat., 4: 69-77, 1984.
12. Clarke, R., Brunner, N., Katzenellenbogen, B. S., Thompson, E. Q., Normal, M. J., Koppi, C., Paik, S., Lippman, M. E., and Dickson, R. B. Progression of human breast cancer cells from hormone-dependent to hormone-independent growth both in vitro and in vivo. Proc. Natl. Acad. Sci. USA, 86: 3649-3653, 1989.
13. Murphy, L. C. Estrogen receptor variants in human breast cancer. Mol. Cell. Endocrinol., 74: C83-C86, 1990.
14. Osborne, C. K., Coronado, E., Allred, D. C., Wiebe, V., and DeGregorio, M. Acquired tamoxifen resistance: correlation with reduced breast tumor levels of tamoxifen and isomerization of trans-4-hydroxytamoxifen. J. Natl. Cancer Inst., 83: 1477-1482, 1991.
15. Graham, M. L., II, Smith, J. A., Jewett, P. B., and Horwitz, K. B. Heterogeneity of progesterone receptor content and remodeling by tamoxifen characterize subpopulations of cultured human breast cancer cells: analysis by quantitative dual parameter flow cytometry. Cancer Res., 52: 593-602, 1992.
16. Garcia, T., Lehrer, S., Bloomer, W. D., and Schachzer, B. A variant estrogen receptor messenger ribonucleic acid is associated with reduced levels of estrogen binding in human mammary tumors. Mol. Endocrinol., 2: 785-791, 1988.
17. Murphy, L. C., and Dorzlaw, H. Variant estrogen receptor mRNA species detected in human breast cancer biopsy samples. Mol. Endocrinol., 3: 687-693, 1989.
18. Fuqua, S. A., Fitzgerald, S. D., Chamness, G. C., Tandon, A. K., McDonnell, D. P., Nawaz, Z., O'Malley, B. W., and McGuire, W. L. Variant human breast tumor estrogen receptor with constitutive transcriptional activity. Cancer Res., 51: 105-109, 1991.
19. McGuire, W. L., Chamness, G. C., and Fuqua, S. A. Abnormal estrogen receptor in clinical breast cancer. J. Steroid Biochem. Mol. Biol., 43: 243-247, 1992.
20. McGuire, W. L., Chamness, G. C., and Fuqua, S. A. Estrogen receptor variants in clinical breast cancer. Mol. Endocrinol., 5: 1571-1577, 1991.
21. Sluyser, M. Role of estrogen receptor variants in the development of hormone resistance in breast cancer. Clin. Biochem., 25: 407-414, 1992.
22. Horwitz, K. B. How do breast cancers become hormone resistant? J. Steroid Biochem. Mol. Biol., 49: 295-302, 1994.
23. Wang, Y., and Miksicek, R. J. Identification of a dominant negative form of the human estrogen receptor. Mol. Endocrinol., 5: 1707-1715, 1991.
24. Fuqua, S. A., Fitzgerald, S. D., Allred, D. C., Elledge, R. M., Nawaz, Z., McDonnell, D. P., O'Malley, B. W., Greene, G. L., and McGuire, W. L. Inhibition of estrogen receptor action by a naturally occurring variant in human breast tumors. Cancer Res., 52: 483-486, 1992.
25. Castles, C. G., Fuqua, S. A., Klotz, D. M., and Hill, S. M. Expression of a constitutive active estrogen receptor variant in the estrogen receptor-negative BT-20 human breast cancer cell line. Cancer Res., 53: 5934-5939, 1993.
26. Dorzlaw, H., Alkhalaf, M., and Murphy, L. C. Characterization of estrogen receptor variant mRNAs from human breast cancers. Mol. Endocrinol., 6: 773-785, 1992.
27. Murphy, L. C., Hilsenbeck, S. G., Dorzlaw, H., and Fuqua, S. A. Relationship of clone 4 estrogen receptor variant mRNA expression to some known prognostic variables in human breast cancer. Clin. Cancer Res., 1: 155-159, 1995.
28. Pfeffer, U., Fecarotta, E., Castegnetta, L., and Vidali, G. Estrogen receptor messenger RNA lacking exon 4 in estrogen-responsive human breast cancer cell lines. Cancer Res., 53: 741-743, 1993.
29. Leygue, E. R., Watson, P. H., and Murphy, L. C. Estrogen receptor variants in normal human breast mammary tissue. J. Natl. Cancer Inst., 5: 284-290, 1996.
30. Kuiper, G. G. J. M., and Gustafsson, J-A. The novel estrogen receptor-β subtype: potential role in the cell-and promoter-specific actions of estrogens and anti-estrogens. FEBS Lett., 410: 87-90, 1997.