Characterization of pncA mutations in pyrazinamide-resistant Mycobacterium tuberculosis in Brazil

Antimicrobial Agents and Chemotherapy

Volumn 49, Issue 1, 2005, Pages 444-446

  Sumnienski Rodrigues, Vívian De F ^a,b   Telles, Maria Alice ^c   Ribeiro, Marta Osório ^b   Cafrune, Patrícia Izquierdo ^b   Rossetti, Maria Lucia Rosa ^b   Zaha, Arnaldo ^a  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b FEPPS   (Brazil)

^c INSTITUTO ADOLFO LUTZ   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; PYRAZINAMIDE; TUBERCULOSTATIC AGENT;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENE; BACTERIUM ISOLATE; BRAZIL; FRAMESHIFT MUTATION; GENE MUTATION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PNCA GENE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; STRAIN DIFFERENCE; TUBERCULOSIS;

AMIDOHYDROLASES; ANTITUBERCULAR AGENTS; DRUG RESISTANCE, BACTERIAL; MICROBIAL SENSITIVITY TESTS; MUTATION; MYCOBACTERIUM TUBERCULOSIS; PYRAZINAMIDE; TUBERCULOSIS;

EID: 11244270749     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.49.1.444-446.2005     Document Type: Article

References (34)

1. Brown, T. J., O. Tensel, and G. L. French. 2000. Simultaneous identification and typing of multi-drug-resistant Mycobacterium tuberculosis isolates by analysis of pncA and rpoB. J. Med. Microbiol. 49:651-656.
2. Canetti, G., N. Rist, and J. Grosset. 1963. Mésure de la sensibilité du bacille tuberculeux aux drogues antibaicillares par la méthode des proportins. Rev. Tuberc. Pneumol. 27:217.
3. Cheng, S. J., L. Thibert, T. Sanchez, L. Heifets, and Y. Zhang. 2000. pncA mutations as a major mechanism of pyrazinamide resistance in Mycobacterium tuberculosis: spread of a monoresistant strain in Quebec, Canada. Antimicrob. Agents Chemother. 44:528-532.
4. Friedman, C. R., M. Y. Stoeckle, W. D. Johnson, Jr., and L. W. Riley. 1995. Double-repetitive-element PCR method for subtyping M. tuberculosis clinical isolates. J. Clin. Microbiol. 33:1383-1384.
5. Hannan, M. M., E. P. Desmond, G. P. Morlock, G. H. Mazurek, and J. T. Crawford. 2001. Pyrazinamide-monoresistant Mycobacterium tuberculosis in the United States. J. Clin. Microbiol. 2:647-650.
6. Heifets, L., and P. Lindholm-Levy. 1992. Pyrazinamide sterilizing activity in vitro against semi-dormant Mycobacterium tuberculosis bacterial populations. Am. Rev. Respir. Dis. 145:1223-1225.
7. Hewlett, D., Jr., D. L. Horn, and C. Alfalla. 1995. Drug-resistant tuberculosis: inconsistent results of pyrazinamide susceptibility testing. JAMA 12:916-917.
8. Huang, T. S., S. S. Lee, H. Z. Tu, W. K. Huang, Y. S. Chen, C. K. Huang, S. R. Wann, H. H. Lin, and Y. C. Liu. 2003. Correlation between pyrazinamide activity and pncA mutations in Mycobacterium tuberculosis isolates in Taiwan. Antimicrob. Agents Chemother. 47:3672-3673.
9. Inderlied, C. B., and G. E. Pfyffer. 2003. Susceptibility test methods: mycobacteria, p. 1149-1177. In P. R. Murray, E. J. Baron, J. H. Jorgensen, M. A. Pfaller, and R. H. Yolken (ed.), Manual of clinical microbiology, 8th ed. American Society for Microbiology, Washington, D.C.
10. Kamerbeek, J., L. Schouls, A. Kolk, M. van Agterveld, D. van Soolingen, S. Kuijper, A. Bunschoten, H. Molhuizen, R. Shaw, M. Goyal, and J. D. A. van Embden. 1997. Simultaneous detection and strain differentiation of Mycobacterium tuberculosis for diagnosis and epidemiology. J. Clin. Microbiol. 35:907-914.
11. Konno, K., H. Nagayama, and S. Oka. 1959. Nicotinamidase in mycobacteria: a method for distinguishing bovine type tubercle bacilli from other mycobacteria. Nature 184:1743-1744.
12. Lee, K. W., J. M. Lee, and K. Jung. 2001. Characterization of pncA mutations of pyrazinamide-resistant Mycobacterium tuberculosis in Korea. J. Korean Med. Sci. 16:537-543.
13. Lemaitre, N., W. Sougakoff, C. Truffot-Pernot, and V. Jarlier. 1999. Characterization of new mutations in pyrazinamide-resistant strains of Mycobacterium tuberculosis and identification of conserved regions important for the catalytic activity of the pyrazinamidase pncA. Antimicrob. Agents Chemother. 43:1761-1763.
14. Marttila, H. J., M. Marjamaki, E. Vyshnevskaya, B. I. Vyshnevskiy, T. F. Otten, A. V. Vasilyef, and M. K. Viljanen. 1999. pncA mutations in pyrazinamide-resistant Mycobacterium tuberculosis isolates from northwestern Russia. Antimicrob. Agents Chemother. 43:1764-1766.
15. McClatchy, J. K., A. Y. Tsang, and M. S. Cernich. 1981. Use of pyrazinamidase activity on Mycobacterium tuberculosis as a rapid method for determination of pyrazinamide susceptibility. Antimicrob. Agents Chemother. 4:556-557.
16. Mestdagh, M., P. A. Fonyeyne, L. Realini, R. Rossau, G. Jannes, W. Mijs, K. A. L. De Smith, F. Portaels, and E. van den Eechhouut. 1999. Relationship between pyrazinamide resistance, loss of pyrazinamidase activity, and mutations in the pncA locus in multidrug-resistant clinical isolates of Mycobacterium tuberculosis. Antimicrob. Agents Chemother. 43:2317-2319.
17. Miller, M. A., L. Thibert, F. Desjardins, S. H. Siddiqi, and A. Dascal. 1996. Growth inhibition of Mycobacterium tuberculosis by polyoxyethylene stearate present in the BACTEC pyrazinamide susceptibility test. J. Clin. Microbiol. 34:84-86.
18. Mitchison, D. A. 1985. The action of antituberculosis drugs in short-course chemoterapy. Tubercule 66:219-225.
19. Miyagi, C., N. Yamane, B. Yogesh, H. Ano, and T. Takashima. 2004. Genetic and phenotypic characterization of pyrazinamide-resistant Mycobacterium tuberculosis complex isolates in Japan. Diagn. Microbiol. Infect. Dis. 48:111-116.
20. Morlock, G. P., J. T. Crawford, W. R. Butler, S. E. Brim, D. Sikes, G. H. Mazurek, C. L. Woodley, and R. C. Cooksey. 2000. Phenotypic characterization of pncA mutants of Mycobacterium tuberculosis. Antimicrob. Agents Chemother. 44:2291-2295.
21. Park, S. K., J. Y. Lee, C. L. Chang, M. K. Lee, H. C. Son, C. M. Kim, H. J. Jang, H. K. Park, and S. H. Jeong. 2001. pncA mutations in clinical Mycobacterium tuberculosis isolates from Korea. BMC Infect. Dis. 1:4.
22. Portugal, I., L. Barreiro, J. Moniz-Pereira, and L. Brum. 2004. pncA mutations in pyrazinamide-resistant Mycobacterium tuberculosis isolates in Portugal. Antimicrob. Agents Chemother. 7:2736-2738.
23. Salfinger, M., and L. B. Heifets. 1988. Determination of pyrazinamide MICs for Mycobacterium tuberculosis at different pHs by the radiometric method. Antimicrob. Agents Chemother. 7:1002-1004.
24. Scorpio, A., and Y. Zhang. 1996. Mutations in pncA, a gene encoding pyrazinamidase/nicotinamidase, cause resistance to antituberculous drug pyrazinamide in tubercule bacillus. Nat. Med. 2:662-667.
25. Scorpio, A., P. Lindholm-Levy, L. Heifets, R. Gilman, S. Siddiqi, M. Cynamon, and Y. Zhang. 1997. Characterization of pncA mutations in pyrazinamide-resistant Mycobacterium tuberculosis. Antimicrob. Agents Chemother. 41:540-543.
26. Snider, D. E., J. Graczyk, E. Bek, and J. Rogowski. 1984. Supervised six-months treatment of newly diagnosed pulmonary tuberculosis using isoniazid, rifampin, and pyrazinamide with and without streptomycin. Am. Rev. Respir. Dis. 130:1091-1094.
27. Sreevatsan, S., X. Pan, Y. Zhang, B. N. Kreiswirth, and J. M. Musser. 1997. Mutations associated with pyrazinamidase resistance in pncA of Mycobacterium tuberculosis complex organisms. Antimicrob. Agents Chemother. 41:636-640.
28. Suzuki, Y., A. Suzuki, A. Tamaru, C. Katsukawa, and H. Oda. 2002. Rapid detection of pyrazinamide-resistant Mycobacterium tuberculosis by a PCR-based in vitro system. J. Clin. Microbiol. 2:501-507.
29. Trivedi, S. S., and S. G. Desai. 1987. Pyrazinamidase activity of Mycobacterium tuberculosis - a test of sensitivity to pyrazinamide. Tubercle 3:221-224.
30. van Embden, J. D. A., M. D. Cave, J. D. Crawford, J. W. Dale, K. D. Eisenach, B. Gicquel, W. M. Hermans, C. Martin, R. McAdam, M. T. Shinnick, and P. M. Small. 1993. Strain identification of Mycobacterium tuberculosis by DNA fingerprinting: recommendations for a standardized methodology. J. Clin. Microbiol. 31:406-409.
31. Wade, M. M., D. Volokhov, M. Peredelchuk, V. Chizhikov, and Y. Zhang. 2004. Accurate mapping of mutations of pyrazinamide-resistant Mycobacterium tuberculosis strains with a scanning-frame oligonucleotide microarray. Diagn. Microbiol. Infect. Dis. 49:89-97.
32. Wayne, L. G. 1974. Simple pyrazinamidase and urease tests for routine identification of mycobacteria. Am. Rev. Respir. Dis. 1:147-151.
33. Zhang, Y., and D. Mitchison. 2003. The curious characteristics of pyrazinamide: a review. Int. J. Tuberc. Lung Dis. 1:6-21.
34. Zhang, Y., A. Scorpio, H. Nikaido, and Z. Sun. 1999. Role of acid pH and deficient efflux of pyrazinoic acid in unique susceptibility of Mycobacterium tuberculosis to pyrazinamide. J. Bacteriol. 7:2044-2049.