Structure-activity relationships of novel inhibitors of glyceraldehyde-3-phosphate dehydrogenase

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 9, 2004, Pages 2199-2204

  Leitão, Andrei ^a   Andricopulo, Adriano D ^b   Oliva, Glaucius ^b   Pupo, Mônica T ^b   De Marchi, Anderson A ^b   Vieira, Paulo C ^c   Da Silva, Maria Fátima G F ^c   Ferreira, Vitor F ^d   De Souza, Maria Cecília B V ^d   Sá, Marcus M ^e   Moraes, Valéria R S ^f   Montanari, Carlos A ^a  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

^c FEDERAL UNIVERSITY OF SÃO CARLOS   (Brazil)

^d FLUMINENSE FEDERAL UNIVERSITY   (Brazil)

^e FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

^f FEDERAL UNIVERSITY OF SERGIPE   (Brazil)

Author keywords

3D QSAR; Chagas disease; Enzyme inibitors

Indexed keywords

COUMARIN DERIVATIVE; ENZYME INHIBITOR; FLAVONOID; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE INHIBITOR; NUCLEOSIDE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CALCULATION; CONTROLLED STUDY; DRUG ABSORPTION; DRUG DESIGN; DRUG POTENCY; DRUG PROTEIN BINDING; DRUG SCREENING; DRUG SELECTIVITY; DRUG STRUCTURE; ENZYME ACTIVE SITE; ENZYME BINDING; HUMAN; HUMAN CELL; NONHUMAN; PRINCIPAL COMPONENT ANALYSIS; QUANTITATIVE STRUCTURE ACTIVITY RELATION; TRYPANOSOMA BRUCEI; TRYPANOSOMA CRUZI;

ENZYME INHIBITORS; GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE (NADP+); QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 11144357543     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.02.025     Document Type: Article

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