Na +/H + exchange inhibition in hypertrophied myocardium subjected to cardioplegic arrest: An effective cardioprotective approach

European Journal of Cardio-thoracic Surgery

Volumn 27, Issue 1, 2005, Pages 111-116

  Kevelaitis, Egidijus ^c   Qureshi, Aasim A ^d   Mouas, Christian ^b   Marotte, Francoise ^b   Kevelaitiene, Sigita ^c   Avkiran, Metin ^d   Menasché, Philippe ^a  

^a HÔPITAL EUROPÉEN GEORGES POMPIDOU   (France)

^b HÔPITAL LARIBOISIÈRE   (France)

^c KAUNAS UNIVERSITY OF MEDICINE   (Lithuania)

^d ST THOMAS HOSPITAL   (United Kingdom)

Author keywords

Cardioplegia; Ischemia reperfusion; Left ventricular function; Myocardial hypertrophy; Myocardial injury; Na+ H+exchange inhibitor

Indexed keywords

BLOCKING AGENT; CARIPORIDE; CREATINE KINASE; SEROTONIN; SODIUM PROTON EXCHANGE INHIBITOR; SODIUM PROTON EXCHANGE PROTEIN 1; UNCLASSIFIED DRUG;

AORTA COARCTATION; ARTICLE; CARDIOPLEGIA; CLIP; CONTROLLED STUDY; CORONARY ARTERY DILATATION; ENDOTHELIUM; ENZYME RELEASE; FEMALE; HEART ARREST; HEART LEFT VENTRICLE HYPERTROPHY; HEART MUSCLE INJURY; HEART PROTECTION; HEART SURGERY; HEART VENTRICLE FUNCTION; HEART VENTRICLE HYPERTROPHY; ION EXCHANGE; NONHUMAN; PRIORITY JOURNAL; PROTON SODIUM EXCHANGE; RAT; REPERFUSION;

ANIMALS; CARDIOMEGALY; CARDIOTONIC AGENTS; CREATINE KINASE; FEMALE; GUANIDINES; HEART; HEART ARREST, INDUCED; HEART VENTRICLES; MYOCARDIAL CONTRACTION; MYOCARDIAL REPERFUSION; RATS; RATS, WISTAR; SODIUM-HYDROGEN ANTIPORTER; SULFONES; VASODILATION; VENTRICULAR FUNCTION, LEFT;

EID: 11144307315     PISSN: 10107940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejcts.2004.08.032     Document Type: Article

References (25)

1. I. Friehs, and P.J. del Nido Increased susceptibility of hypertrophied hearts to ischemic injury Ann Thorac Surg 75 2003 S678 S684
2. C.A. Walker, F.A. Crawford, and F.G. Spinale Myocyte contractile dysfunction with hypertrophy and failure: relevance to cardiac surgery J Thorac Cardiovasc Surg 119 2000 388 400
3. 2+] during ischaemia and reperfusion Eur Heart J Suppl 1 Suppl K 1999 K18 K30
4. 2+ overload and prolonged acidosis on reperfusion Circulation 101 2000 2749 2755
5. + exchange inhibitors for cardioprotective therapy: progress, problems and prospects J Am Coll Cardiol 39 2002 747 753
6. P. Théroux, B.R. Chaitman, N. Danchin, L. Erhardt, T. Meinertz, J.S. Schroeder, G. Tognoni, H.D. White, J.T. Willerson, and A. Jessel Inhibition of the sodium-hydrogen exchanger with cariporide to prevent myocardial infarction in high-risk ischemic situations. Main results of the GUARDIAN trial Circulation 102 2000 3032 3038
7. + exchange inhibitor eniporide as an adjunct to early reperfusion therapy for acute myocardial infarction: results of the Evaluation of the Safety and Cardioprotective Effects of Eniporide in Acute Myocardial Infarction (ESCAMI) trial J Am Coll Cardiol 38 2001 1644 1650
8. + inhibition: which is the best protective strategy for heart transplants? J Thorac Cardiovasc Surg 121 2001 155 162
9. S. Schiaffino, J.L. Samuel, D. Sassoon, A.M. Lompré, I. Garner, F. Marotte, M. Buckingham, L. Rappaport, and K. Schwartz Nonsynchronous accumulation of α-skeletal actin and β-myosin heavy chain mRNAs during early stages of pressure-overload-induced cardiac hypertrophy demonstrated by in situ hydridization Circ Res 64 1989 937 948
10. W. Scholz, U. Albus, L. Counillon, H. Gogelein, H.J. Lang, W. Linz, A. Weichert, and B.A. Scholkens Protective effects of HOE 642, a selective sodium-hydrogen exchange subtype 1 inhibitor, on cardiac ischaemia and reperfusion Cardiovasc Res 29 1995 260 268
11. + exchanger activity and its inhibition by cariporide in cardiac ventricular myocytes Br J Pharmacol 134 2001 1587 1595
12. i and diastolic function after ischemia during reperfusion in pig hearts in situ Am J Physiol Heart Circ Physiol 280 2001 H830 H834
13. + exchange Am J Physiol Heart Circ Physiol 268 1995 H1531 H1539
14. + exchange Cardiovasc Res 35 1997 80 89
15. + exchange hyperactivity and myocardial hypertrophy: are they linked phenomena? Cardiovasc Res 44 1999 462 467
16. + exchanger activity: signalling and significance Cardiovasc Res 57 2003 942 952
17. + exchange is impaired in cardiac hypertrophy J Clin Invest 99 1997 125 135
18. 1-adrenergic receptor transgenic mice Circ Res 90 2002 814 819
19. + exchanger Cardiovasc Res 53 2002 862 868
20. M.L. Marcus, D.B. Doty, and L.F. Hiratzka A mechanism for angina pectoris in patients with aortic stenosis and normal coronary arteries N Engl J Med 307 1982 1362 1367
21. C.B. Treasure, L.J. Klein, J.A. Vita, S.V. Manoukian, G.H. Renwick, A.P. Selwyn, P. Ganz, and R.W. Alexander Hypertension and left ventricular hypertrophy are associated with impaired endothelium-mediated relaxation in human coronary resistance vessels Circulation 87 1993 86 93
22. M.P. Kingsbury, M.A. Turner, N.A. Flores, E. Bovill, and D.J. Sheridan Endogenous and exogenous coronary vasodilatation are attenuated in cardiac hypertrophy: a morphological defect? J Mol Cell Cardiol 32 2000 527 538
23. A. Bouloumié, J. Bauersachs, W. Linz, B.A. Scholkens, G. Wiemer, I. Fleming, and R. Busse Endothelial dysfunction coincides with an enhanced nitric oxide synthase expression and superoxide anion production Hypertension 30 1997 934 941
24. + exchange subtype 1 inhibition reduces endothelial dysfunction in vessels from stunned myocardium Am J Physiol Heart Circ Physiol 281 2001 H1575 H1582
25. + exchange J Thorac Cardiovasc Surg 124 2002 1113 1121