Photostability of sunscreen products influences the efficiency of protection with regard to UV-induced genotoxic or photoageing-related endpoints

British Journal of Dermatology

Volumn 151, Issue 6, 2004, Pages 1234-1244

  Marrot, L ^a   Belaidi J P ^a   Lejeune, F ^a   Meunier, J R ^a   Asselineau, D ^a   Bernerd, F ^a  

^a L ORÉAL RECHERCHE   (France)

Author keywords

DNA photodamage; p53; Photoageing; Reconstructed skin; Sunscreens; Ultraviolet A radiation

Indexed keywords

BIOLOGICAL MARKER; DNA; INTERSTITIAL COLLAGENASE; LIQUID PARAFFIN; MIGLYOL; PROTEIN P53; SORBITAN ESTER; SUNSCREEN;

ARTICLE; ARTIFICIAL SKIN; COMET ASSAY; CONTROLLED STUDY; DNA DAMAGE; DNA STRAND BREAKAGE; DRUG STABILITY; ENZYME RELEASE; FIBROBLAST; GENOTOXICITY; HUMAN; HUMAN CELL; IN VITRO STUDY; KERATINOCYTE; LIGHT PROTECTION; MODEL; MORPHOLOGY; PHOTOAGING; PHOTOSTABILITY; PHOTOTOXICITY; PRIORITY JOURNAL; RADIATION ABSORPTION; RADIATION EXPOSURE; RADIATION INJURY; RADIATION PROTECTION; RECONSTRUCTED SKIN; RECONSTRUCTED SKIN MODEL; SIMULATED SOLAR ULTRAVIOLET A RADIATION; SIMULATION; SKIN CANCER; SKIN PROTECTION; SOLAR RADIATION; SUN EXPOSURE; ULTRAVIOLET A RADIATION; ULTRAVIOLET RADIATION;

CELL CULTURE TECHNIQUES; COMET ASSAY; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, RADIATION; DRUG STABILITY; HUMANS; KERATINOCYTES; SKIN; SKIN AGING; SKIN, ARTIFICIAL; SUNSCREENING AGENTS; TISSUE CULTURE TECHNIQUES; TUMOR SUPPRESSOR PROTEIN P53; ULTRAVIOLET RAYS;

EID: 11144299558     PISSN: 00070963     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2133.2004.06173.x     Document Type: Article

References (46)

1. De Gruijl FR. Skin cancer and solar UV radiation. Eur J Cancer 2000; 35: 2003-9.
2. Daya-Grosjean L, Dumaz N, Sarasin A. The specificity of p53 mutation spectra in sunlight induced human cancers. J Photochem Photobiol B Biol 1995; 28: 114-24.
3. Ananthaswamy HN, Loughlin SM, Cox P et al. Sunlight and skin cancer: inhibition of p53 mutations in UV-irradiated mouse skin by sunscreens. Nat Med 1997; 3: 510-14.
4. de Laat JM, de Gruijl FR. The role of UVA in the etiology of nonmelanoma skin cancer. Cancer Surv 1996; 26: 173-92.
5. Burren R, Scaletta C, Frenk E et al. Sunlight and carcinogenesis: expression of p53 and pyrimidine dimers in human skin following UVA I, UVA I + II and solar simulating radiations. Int J Cancer 1998; 76: 201-6.
6. Hattori-Nakakuki Y, Nishigori C, Okamoto K et al. Formation of 8-hydroxy-2′-deoxyguanosine in epidermis of hairless mice exposed to near-UV. Biochem Biophys Res Commun 1994; 201: 1132-9.
7. Kvam E, Tyrrell RM. Induction of oxidative DNA base damage in human skin cells by UV and near visible radiation. Carcinogenesis 1997; 18: 2379-84.
8. Pflaum M, Kielbassa C, Garmyn M, Epe B. Oxidative DNA damage induced by visible light in mammalian cells: extent, inhibition by antioxidants and genotoxic effects. Mutation Res 1998; 408: 137-46.
9. Oliveira HS, Gonqalo M, Figueiredo AC. Photosensitivity to lomefloxacin, a clinical and photobiological study. Photodermatol Photoimmunol Photomed 2000; 16: 116-20.
10. Vogelstein B, Lane D, Levine AJ. Surfing the p53 network. Nature 2000; 408: 307-10.
11. Dumaz N, Duthu A, Ehrhart JC et al. Prolonged p53 protein accumulation in TTD fibroblasts dependent on unrepaired pyrimidine dimers on the transcribed strands of cellular genes. Mol Carcinogenesis 1997; 20: 340-7.
12. Marrot L, Belaïdi JP, Chaubo C et al. An in vitro strategy to evaluate the phototoxicity of solar UV at the molecular and cellular level: application to photoprotection assessment. Eur J Dermatol 1998; 8: 403-12.
13. Gilchrest BA. Dermatoheliosis (sun-induced aging). In: Skin and Aging Processes (Gilchrest BA, ed.). Boca Raton: CRC Press, 1989; 97-116.
14. Kligman LH. Photoaging: manifestations prevention, and treatment. Dermatol Clin 1986; 4: 517-28.
15. Oikarinen A, Karvonen J, Uitto J, Hannuksela M. Connective tissue alterations in skin exposed to natural and therapeutic UV-radiation. Photodermatol 1985; 2: 15-26.
16. Talwar HS, Griffiths CE, Fisher GJ et al. Reduced type I and type III procollagens in photodamaged adult human skin. J Invest Dermatol 1995; 105: 285-90.
17. Varani J, Spearman D, Perone P et al. Inhibition of type I procollagen synthesis by damaged collagen in photoaged skin and by collagenase-degraded collagen in vitro. Am J Pathol 2001; 158: 931-42.
18. Fisher GJ, Datta SC, Talwar HS et al. Molecular basis of sun-induced premature skin ageing and retinoid antagonism. Nature 1996; 379: 335-9.
19. Kligman LH, Akin FJ, Kligman AM. The contributions of UVA and UVB to connective tissue damage in hairless mice. J Invest Dermatol 1985; 84: 272-6.
20. Fagot D, Asselineau D, Bernerd F. Direct role of human dermal fibroblasts and indirect participation of epidermal keratinocytes in MMP-1 production after UV-B irradiation. Arch Dermatol Res 2002; 293: 576-83.
21. Kohen E, Santus R, Hirschberg J. Optical properties of the skin. In: Photobiology (Kohen E, Santus R, Hirschberg J, eds). London: Academic Press Inc., 1995; 303-21.
22. Lavker RM, Veres DA, Irwin CJ, Kaidbey KH. Quantitative assessment of cumulative damage from repetitive exposures to suberythemogenic doses of UVA in human skin. Photochem Photobiol 1995; 62: 348-52.
23. Lowe NJ, Meyers DP, Wieder JM et al. Low doses of repetitive ultraviolet A induce morphologic changes in human skin. J Invest Dermatol 1995; 105: 739-43.
24. Seite S, Moyal D, Trichard S et al. Mexoryl® SX: a broad spectrum absorption UVA filter protects human skin from the effects of repeated suberythemal doses of UVA. J Photochem Photobiol B Biol 1998; 44: 69-76.
25. Bernerd F, Asselineau D. UVA exposure of human skin reconstructed in vitro induces apoptosis of dermal fibroblasts: subsequent connective tissue repair and implications in photoaging. Cell Death Differ 1998; 5: 792-802.
26. Scharffetter K, Wlaschek M, Hogg A et al. UVA irradiation induces collagenase in human dermal fibroblasts in vitro and in vivo. Arch Dermatol Res 1991; 283: 506-11.
27. Marrot L, Belaidi JP, Meunier JR. Comet assay combined with p53 detection as a sensitive approach for DNA photoprotection assessment in vitro, Exp Dermatol 2002; 11 (Suppl. 1): 33-6.
28. Bernerd F, Asselineau D. Successive alteration and recovery of epidermal differentiation and morphogenesis after specific UVB-damages in skin reconstructed in vitro. Dev Biol 1997; 183: 123-38.
29. Rheinwald JG, Green H. Serial cultivation of strains of human keratinocytes: the formation of keratinizing colonies from single cells. Cell 1975; 6: 331-43.
30. Asselineau D, Bernard BA, Bailly C, Darmon M. Epidermal morphogenesis and induction of 67kD keratin polypeptide by culture at the liquid-air interface. Exp Cell Res 1985; 159: 536-9.
31. Bernerd F, Vioux C, Asselineau D. Evaluation of the protective effect of sunscreens on in vitro reconstructed human skin exposed to UVB or UVA irradiation. Photochem Photobiol 2000; 71: 314-20.
32. Alapetite CA, Wächter T, Sage E, Moustacchi E. Use of alkaline comet assay to detect DNA repair deficiencies in human fibroblasts exposed to UVC, UVB, UVA and γ rays. Int J Radiat Biol 1996; 69: 359-69.
33. Dusinska M, Collins A. Detection of oxidized purines and UV-induced photoproducts in DNA of single cells by inclusion of lesion-specific enzymes in the comet assay. Alternatives Lab Anim 1996; 24: 405-11.
34. Strauss GHS. Non-random cell killing in cryopreservation. Mutation Res 1991; 252: 1-15.
35. Bernerd F, Vioux C, Lejeune F, Asselineau D. The sun protection factor (SPF) inadequately defines broad spectrum photoprotection: demonstration using skin reconstructed in vitro exposed to UVA, UVB or UV-solar simulated radiation. Eur J Dermatol 2003; 13: 242-9.
36. Kielbassa C, Epe B. DNA damage by UV and visible light and its wavelength dependence, Methods Enzymol 2000; 319: 436-45.
37. Deflandre A, Dubois M, Forestier S, Richard H. Sunscreen compositions based on di,benzoil:methane derivatives photostabilized with 3,3-diphenyl:acrylate derivatives. Patent No. W09111989. World International Patent Office, 1991.
38. Lowe NJ. Sun protection factor comparative techniques and selection of UV sources. In: Sunscreens, Development, Evaluation and Regulatory Aspects (Lowe NJ, Shaath N, eds). New York: Marcel Dekker, 1990; 379-94.
39. Kligman L, Agin PP, Sayre RM. Broad-spectrum sunscreens with UVA I and UVA II absorbers provide increased protection against solar-simulating radiation-induced dermal damage in hairless mice. J Soc Cosmet Chem 1996; 47: 129-55.
40. Marrot L, Belaidi JP, Meunier IR et al. The human melanocyte as a particular target for UVA radiation and an end-point for photoprotection assessment. Photochem Photobiol 1999; 69: 686-93.
41. Seite S, Moyal D, Verdier MP et al. Accumulated p53 protein and UVA protection level of sunscreens. Photodermatol Photoimmunol Photomed 2000; 16: 3-9.
42. Marrot L, Belaïdi JP, Agapakis-Causse C. Comet assay as a sensitive approach in vitro for UVA photoprotection assessment. In: Alternatives to Animal Testing II (Clark D, Lisansky S, Macmillan R, eds). Newbury: CPL Press, 1999; 142-7.
43. Diffey BL. A method for broad spectrum classification of sunscreens. Int J Cosmet Sci 1994; 16: 47-52.
44. Schaeffer H, Chardon A, Moyal D. Photoprotection of skin against UVA damage. Methods Enzymol 2000; 319: 445-65.
45. Klecak G, Urbach F, Urwyler H. Fluoroquinolone antibacterials enhance UVA-induced skin tumors. J Photochem Photobiol B 1997; 37: 174-81.
46. Chételat AA, Albertini S, Gocke E. The photomutagenicity of fluoroquinolones in tests for gene mutation, chromosomal aberration, gene conversion and DNA breakage (Comet assay), Mutagenesis 1996; 11: 497-504.