ACAT1 deficiency disrupts cholesterol efflux and alters cellular morphology in macrophages

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 25, Issue 1, 2005, Pages 128-134

  Dove, Dwayne E ^a   Su, Yan Ru ^a   Zhang, Wenwu ^a   Jerome, W Gray ^a,b   Swift, Larry L ^a   Linton, MacRae F ^a,b   Fazio, Sergio ^a  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

ACAT1; Atherosclerosis; ATP binding cassette A1; Cholesterol efflux; Macrophages

Indexed keywords

ACETYL LOW DENSITY LIPOPROTEIN; CHOLESTEROL; CHOLESTEROL ACYLTRANSFERASE; CHOLESTEROL ACYLTRANSFERASE 1; FAT DROPLET; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; CELL STRUCTURE; CELL TRANSPORT; CELL VACUOLE; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; ENZYME DEFICIENCY; GENE DELETION; GENE EXPRESSION REGULATION; HYPERLIPIDEMIA; LIPID STORAGE; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; UPREGULATION; WILD TYPE;

ACETYL-COA C-ACETYLTRANSFERASE; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BIOLOGICAL TRANSPORT, ACTIVE; CHOLESTEROL; CHOLESTEROL ESTERS; CHOLESTEROL, LDL; ENDOSOMES; FOAM CELLS; LYSOSOMES; MACROPHAGES, PERITONEAL; MICE; MICROSCOPY, ELECTRON, TRANSMISSION; MICROSCOPY, FLUORESCENCE; RNA, MESSENGER; STEROL O-ACYLTRANSFERASE; TRITIUM;

EID: 11144227415     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.0000148323.94021.e5     Document Type: Article

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