Bronchial mucosal mast cells in asymptomatic smokers relation to structure, lung function and emphysema

Respiratory Medicine

Volumn 99, Issue 1, 2005, Pages 75-83

  Ekberg Jansson, Ann ^a   Amin, K ^b   Bake, B ^a   Rosengren, A ^a   Tylen U ^a   Venge, P ^b   Lofdahl C G ^c  

^a SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

^b UPPSALA UNIVERSITY   (Sweden)

^c LUND UNIVERSITY   (Sweden)

Author keywords

Chronic bronchitis; High resolution computed tomography; Lung function; Mast cells; Respiratory symptoms

Indexed keywords

LAMININ; TENASCIN;

ARTICLE; BRONCHUS BIOPSY; BRONCHUS MUCOSA; CELL COUNT; CELL POPULATION; CIGARETTE SMOKING; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; FUNCTIONAL RESIDUAL CAPACITY; HIGH RESOLUTION COMPUTER TOMOGRAPHY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; LAMINA PROPRIA; LUNG EMPHYSEMA; LUNG FUNCTION TEST; MAST CELL; PRIORITY JOURNAL; RESIDUAL VOLUME; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; TOTAL LUNG CAPACITY;

AGED; BIOPSY; BRONCHI; CELL COUNT; HUMANS; MALE; MAST CELLS; MUSCLE, SMOOTH; PULMONARY EMPHYSEMA; RESPIRATORY MECHANICS; RESPIRATORY MUCOSA; SMOKING; TOMOGRAPHY, X-RAY COMPUTED;

EID: 10944269808     PISSN: 09546111     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.rmed.2004.05.013     Document Type: Article

References (32)

1. Thompson A. Daughton D. Robbins R. Ghafouri M. Oehlerking M. Rennard S. Intraluminal airway inflammation in chronic bronchitis. Characterization and correlation with clinical parameters Am Rev Respir Dis 140 1989 1527-1537
2. Jimenez R.C.A. Rajas O. Ruiz A. et al. Bronchoalveolar lavage in smokers: Quantification of alveolar macrophages and neutrophils as markers of bronchial obstruction In vivo 12 1998 427-430
3. Linden M. Rasmussen J.B. Piitulainen E. et al. Airway inflammation in smokers with non-obstructive and obstructive chronic bronchitis Am Rev Respir Dis 148 1993 1226-1232
4. Keatings V.M. Barnes P.J. Granulocyte activation markers in induced sputum: Comparison between chronic obstructive pulmonary disease, asthma, and normal subjects Am J Respir Crit Care Med 155 1997 449-453
5. Ekberg-Jansson A. Andersson B. Enander I. et al. Neutrophil-associated activation markers in healthy smokers relate to a fall in DLCO and to emphysematous changes on high resolution CT Respir Med 95 2001 363-373
6. Mueller R. Chanez P. Campbell A.M. Bousquet J. Heusser C. Bullock G.R. Different cytokine patterns in bronchial biopsies in asthma and chronic bronchitis Respir Med 90 1996 79-85
7. Saetta M. Turato G. Facchini F.M. et al. Inflammatory cells in the bronchial glands of smokers with chronic bronchitis Am J Respir Crit Care Med 156 1997 1633-1639
8. di Stefano A. Capelli A. Lusuardi M. et al. Severity of airflow limitation is associated with severity of airway inflammation in smokers Am J Respir Crit Care Med 158 1998 1277-1285
9. Saetta M. di Stefano A. Maestrelli P. et al. Activated T-lymphocytes and macrophages in bronchial mucosa of subjects with chronic bronchitis Am Rev Respir Dis 147 1993 301-306
10. 1 Am J Respir Crit Care Med 155 1997 852-857
11. Lams B.E.A. Sousa A.R. Rees P.J. Lee T.H. Immunopathology of the small-airway submucosa in smokers with and without chronic obstructive pulmonary disease Am J Respir Crit Care Med 158 1998 1518-1523
12. Ekberg-Jansson A. Andersson B. Arvå E. Nilsson O. Löfdahl C.G. The expression of lymphocyte surface antigens in bronchial biopsies, bronchoalveolar lavage cells and blood cells in healthy smoking and never-smoking men, 60 years old Respir Med 94 2000 264-272
13. Lacoste J.Y. Bousquet J. Chanez P. et al. Eosinophilic and neutrophilic inflammation in asthma, chronic bronchitis, and chronic obstructive pulmonary disease J Allergy Clin Immunol 92 1993 537-548
14. Sun G. Stacey M.A. Vittori E. et al. Cellular and molecular characteristics of inflammation in chronic bronchitis Eur J Clin Invest 28 1998 364-372
15. di Stefano A. Turato G. Maestrelli P. et al. Airflow limitation in chronic bronchitis is associated with T-lymphocyte and macrophage infiltration of the bronchial mucosa Am J Respir Crit Care Med 153 1996 629-632
16. Grashoff W.F. Sont J.K. Sterk P.J. et al. Chronic obstructive pulmonary disease: Role of bronchiolar mast cells and macrophages Am J Pathol 151 1997 1785-1790
17. Pesci A. Rossi G. Bertorelli G. Aufiero A. Zanon P. Olivieri D. Mast cells in the airway lumen and bronchial mucosa of patients with chronic bronchitis Am J Respir Crit Care Med 149 1994 1311-1316
18. Lamb D. Lumsden A. Intra-epithelial mast cells in human airway epithelium: Evidence for smoking-induced changes in their frequency Thorax 37 1982 334-342
19. Brightling C.E. Bradding P. Symon F.A. Holgate S.T. Wardlaw A.J. Pavord I.D. Mast-cell infiltration of airway smooth muscle in asthma N Engl J Med 346 2002 1699-1705
20. Amin K. Ekberg-Jansson A. Löfdahl C.G. Venge P. Relationship between inflammatory cells and structural changes in the lungs of asymptomatic and never smokers: A biopsy study Thorax 58 2003 135-142
21. Rosengren A. Orth-Gomér K. Wedel H. Wilhelmsen L. Stressful life events, social support, and mortality in men born in 1933 BMJ 307 1993 1102-1105
22. Tylen U. Boijsen M. Ekberg-Jansson A. Bake B. Löfdahl C.G. Emphysematous lesions and lung function in healthy smokers 60 years of age Respir Med 94 2000 38-43
23. Amin K. Ludviksdottir D. Janson C. et al. Inflammation and structural changes in the airways of patients with atopic and nonatopic asthma. BHR Group Am J Respir Crit Care Med 162 2000 2295-2301
24. Quanjer P.H. Tammeling G.J. Cotes J.E. Pedersen O.F. Peslin R. Yernault J.C. Lung volumes and forced ventilatory flows. Official statement of the European Respiratory Society Eur Respir J 6 1993 5-40
25. Salorinne Y. Single-breath pulmonary diffusing capacity. Reference values and application in connective tissue diseases and in various lung diseases. Scand J Respir Dis 1976 (suppl 96):9-28
26. Bergin C.J. Muller N.L. Miller R.R. CT in the qualitative assessment of emphysema J Thorac Imag l 1986 94-103
27. Burney P.G.J. Luczynska C. Chinn S. Jarvis D. The European Community Respiratory Health Survey Eur Respir J 7 1994 954-960
28. Ekberg-Jansson A. Bake B. Andersson B. Skoogh B.E. Löfdahl C.G. Respiratory symptoms relate to physiologic changes and inflammatory markers reflecting central but not peripheral airways. A study in 60-year-old "healthy" smokers and never-smokers Respir Med 95 2001 40-47
29. Saetta M. di Stefano A. Maestrelli P. et al. Airway eosinophilia and expression of interleukin-5 protein in asthma and in exacerbations of chronic bronchitis Clin Exp Allergy 26 1995 766-774
30. Saetta M. di Stefano A. Turato G. et al. CD8+ T-lymphocytes in peripheral airways of smokers with chronic obstructive pulmonary disease Am J Respir Crit Care Med 157 1998 822-826
31. Nadel J.A. Role of mast cell and neutrophil proteases in airway secretion Am Rev Respir Dis 144 1991 S48-S51
32. O'Donnell D.E. Revill S.M. Webb K.A. Dynamic hyperinflation and exercise intolerance in chronic obstructive pulmonary disease Am J Respir Crit Care Med 164 2001 770-777