Cellular and molecular characteristics of inflammation in chronic bronchitis

European Journal of Clinical Investigation

Volumn 28, Issue 5, 1998, Pages 364-372

  Sun, G ^a,b,c,d   Stacey, M A ^a,b,c,d   Vittori, E ^a,b,c,d   Marini, M ^a,b,c,d   Bellini, A ^e   Kleimberg, J ^e   Mattoli, S ^a,b,c,d  

^a Institute of Experimental Medicine   (Italy)

^b Ital Found of Exp Medicine   (Italy)

^c Ital Found of Exp Medicine   (Italy)

^d Ital Found of Exp Medicine   (Italy)

^e UNIVERSITY OF MILAN   (Italy)

Author keywords

Airway inflammation; Chronic bronchitis; Cytokines; Interleukin 5; Interleukin 8

Indexed keywords

CYTOKINE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 5; INTERLEUKIN 8;

ADULT; AIRWAY OBSTRUCTION; ARTICLE; CHRONIC BRONCHITIS; CIGARETTE SMOKING; CLINICAL ARTICLE; FEMALE; HUMAN; INFLAMMATION; LUNG LAVAGE; MACROPHAGE ACTIVATION; MALE; MOLECULAR BIOLOGY; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE ACTIVATION;

ADULT; AGED; BRONCHIAL PROVOCATION TESTS; BRONCHITIS; BRONCHOALVEOLAR LAVAGE FLUID; CHRONIC DISEASE; CYTOKINES; FEMALE; GENE EXPRESSION; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; METHACHOLINE CHLORIDE; MIDDLE AGED; RESPIRATORY FUNCTION TESTS; SMOKING;

EID: 0031810615     PISSN: 00142972     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2362.1998.00285.x     Document Type: Article

References (52)

1. Medical Section of the American Lung Association. Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease (COPD) and asthma. Am Rev Respir Dis 1987; 136: 225-43.
2. Diener CF, Burrows B. Further observations on the course and prognosis of chronic obstructive lung disease. Am Rev Respir Dis 1975; 111: 719-24.
3. Johnston RN, McNeil RS, Smith DH, Legge JS, Fletcher F. Chronic bronchitis: measurements and observations over 10 years. Thorax 1976; 31: 25-9.
4. Fletcher C, Peto R. The natural history of chronic airflow obstruction. Br Med J 1977; 1: 1645-8.
5. Fletcher C, Peto R, Tinker C, Speizer FE. The natural history of chronic bronchitis and emphysema. London: Oxford University Press, 1976; 47.
6. Salvato G. Some histological changes in chronic bronchitis and asthma. Thorax 1968; 23: 168-72.
7. Mullen JBM, Wright JL, Wiggs BR, Parè PD, Hogg JC. Reassessment of inflammation of airways in chronic bronchitis. Br Med J 1985; 291: 1235-9.
8. Martin TR, Raghu G, Maunder RJ, Springmeyer SC. The effect of chronic bronchitis and chronic airflow obstruction on lung cell populations recovered by bronchoalveolar lavage. Am Rev Respir Dis 1985; 132: 254-60.
9. Mullen JBM, Wright JL, Wiggs BR, Parè PD, Hogg JC. Structure of central airways in current smokers and ex-smokers with and without mucous hypersecretion. Thorax 1987; 42: 843-6.
10. Thompson AB, Daughton D, Robbins RA, Ghafouri MA, Oehlerking M, Rennard SI. Intraluminal airway inflammation in chronic bronchitis: characterization and correlation with clinical parameters. Am Rev Respir Dis 1989; 140: 1527-37.
11. Fournier M, Lebargy F, Le Roy Ladurie F, Lenormand E, Pariente R. Intraepithelial T-lymphocyte subsets in the airways of normal subjects and of patients with chronic bronchitis. Am Rev Respir Dis 1989; 140: 737-42.
12. Lacoste JY, Bousquet J, Chanez P et al. Eosinophilic and neutrophilic inflammation in asthma, chronic bronchitis, and chronic obstructive pulmonary disease. J Allergy Clin Immunol 1993; 92: 537-48.
13. Saetta M, Di Stefano A, Maestrelli P et al. Activated T-lymphocytes and macrophages in bronchial mucosa of subjects with chronic bronchitis. Am Rev Respir Dis 1993; 147: 301-6.
14. Vignola AM, Campbell AM, Chanez P, Bousquet J, Lacoste P, Michel F. HLA-DR expression and ICAM-1 expression on bronchial epithelial cells in asthma and chronic bronchitis. Am Rev Respir Dis 1993; 148: 689-94.
15. Linden M, Rasmussen JB, Piitulainen E, Tunek A, Larson M, Tegner H. Airway inflammation in smokers with nonobstructive and obstructive chronic bronchitis. Am Rev Respir Dis 1993; 148: 1226-32.
16. 1. Am J Respir Crit Care Med 1997; 155: 852-7.
17. Gibson PG, Dolovich J, Denburg J, Ramsdale EH, Hargreave FE. Chronic cough: eosinophilic bronchitis without asthma. Lancet 1989; i: 1346-8.
18. Byrrows B, Earle RH. Course and prognosis of chronic obstructive lung disease: a prospective study of 200 patients. N Engl J Med 1969; 280: 397-404.
19. Traver GE, Cline MG, Burrows B. Predictors of mortality in chronic obstructive pulmonary disease. Am Rev Respir Dis 1979; 119: 895-902.
20. Peto R, Speizer FE, Cochrane AL et al. The relevance in adults of airflow obstruction, but not of mucus hypersecretion, to mortality from chronic lung disease. Am Rev Respir Dis 1983; 128: 491-500.
21. Anthonisen NR, Wright EC, Hodgkin JE. Prognosis in chronic obstructive pulmonary disease. Am Rev Respir Dis 1986; 133: 14-20.
22. Hargreave FE, Ryan G, Thompson NC et al. Bronchial responsiveness to histamine and methacholine in asthma: measurement and clinical significance. J Allergy Clin Immunol 1981; 68: 347-55.
23. Mattoli S, Mattoso VL, Soloperto M, Allegra L, Mattoli S. Cellular and biochemical characteristics of bronchoalveolar lavage fluid in symptomatic nonallergic asthma. J Allergy Clin Immunol 1991; 87: 794-802.
24. Marini M, Avoni E, Hollemborg J, Mattoli S. Cytokine mRNA profile and cell activation in bronchoalveolar lavage fluid from nonatopic patients with symptomatic asthma. Chest 1992; 102: 661-9.
25. NHLBI Workshop Summaries. Summary and recommendations of a workshop on the investigative use of fiberoptic bronchoscopy and bronchoalveolar lavage in asthmatics. Am Rev Respir Dis 1985; 132: 180-2.
26. Marini M, Vittori E, Hollemborg J, Mattoli S. Expression of the potent inflammatory cytokines, granulocyte-macrophage-colony-stimulating factor and interleukin-6 and interleukin-8, in bronchial epithelial cells of patients with asthma. J Allergy Clin Immunol 1992; 89: 1001-9.
27. Mori L, Kleimberg J, Mancini C, Bellini A, Marini M, Mattoli S. Bronchial epithelial cells of atopic patients with asthma lack the ability to inactivate allergens. Biochem Biophys Res Commun 1995; 217: 817-24.
28. Maniatis T, Fritsch EF, Sambrook J. Molecular Cloning: a Laboratory Manual. Cold Spring Harbor, NY. Cold Spring Harbor Laboratory Press, 1982: 382-9.
29. Bellini A, Vittori E, Marini M, Ackerman V, Mattoli S. Intraepithelial dendritic cells and selective activation of Th2-like lymphocytes in patients with atopic asthma. Chest 1993; 103: 997-1005.
30. Conover WJ. Practical non-parametric statistics. New York: John Wiley and Sons, 1980.
31. Tai PC, Spry CJF, Peterson C, Venge P, Olsson I. Monoclonal antibodies distinguish between storage and secreted form of eosinophil cationic protein. Nature 1984; 309: 182-4.
32. Uchiyama T, Nelson DL, Fleisher TA, Waldmann TA. A monoclonal antibody (anti-Tac) reactive with activated and functionally mature human T cells. 2. Expression of Tac antigen on activated cytotoxic killer T cells, suppressor T cells, and on one of two types of helper T cells. J Immunol 1981; 126: 1398-406.
33. Wang JM, Rambaldi A, Biondi A, Chan ZG, Sanderson CJ, Mantovani A. Recombinant human interleukin 5 is a selective eosinophil chemoattractant. Eur J Immunol 1989; 19: 701-5.
34. Rand TH, Silberstein DS, Kornfeld H, Weller PF. Human eosinophils express functional interleukin 2 receptors. J Clin Invest 1991; 88: 825-32.
35. Smith WB, Gamble JR, Clarke-Lewis I, Vadas MA. IL-8 induces neutrophil transendothelial migration. Immunol 1991; 72: 65-72.
36. McCain RW, Holden EP, Blackwell TR, Christman JW. Leukotriene B4 stimulates human polymorphonuclear leukocytes to synthesize and release IL-8 in vitro. Am J Respir Cell Mol Biol 1994; 10: 651-7.
37. Baggiolini M, Dewald B, Moser B. Interleukin-8 and chemotactic cytokines -CXC and CC chemokines. Adv Immunol 1993; 55: 97-179.
38. Marini M, Sciacca F, Colotta F, Mantovani A, Mattoli S. Protective effect of nedocromil sodium on the interleukin-1-induced production of interleukin-8 in human bronchial epithelial cells. J Allergy Clin Immunol 1992; 90: 76-84.
39. Kemeny DM, Noble A, Holmes BJ, Diaz-Sanchez D. Immune regulation: a new role for the CD8+ T cell. Immunol Today 1994; 15: 107-10.
40. Seder RA, Le Gros GG. The functional role of CD8+ T helper type 2 cells. J Exp Med 1995; 181: 5-7.
41. Broide DH, Paine MM, Firestein GS. Eosinophils express interleukin-5 and granulocyte/macrophage colony-stimulating factor mRNA at sites of allergic inflammation in asthmatics. J Clin Invest 1992; 80: 1414-24.
42. Lopez AF, Williamson DJ, Gamble JR et al. Recombinant human granulocyte/macrophage colony-stimulating factor stimulates in vitro mature human eosinophil and neutrophil function, surface receptor expression and survival. J Clin Invest 1986; 78: 1220-8.
43. Ackerman V, Marini M, Vittori E, Bellini A, Vassalli G, Mattoli S. Detection of cytokines and their cell sources in bronchial biopsy specimens from asthmatic patients. Relationship to atopic status, symptoms, and level of airway hyperresponsiveness. Chest 1994; 105: 687-96.
44. Marini M, Soloperto M, Mezzetti M, Fasoli A, Mattoli S. Interleukin-1 binds to specific receptors on human bronchial epithelial cells and upregulate granulocyte-macrophage colony-stimulating factor synthesis and release. Am J Respir Cell Mol Biol 1991; 4: 519-24.
45. Le J, Vilcek J. Tumor necrosis factor and interleukin 1: cytokines with multiple overlapping biological activities. Lab Invest 1987; 56: 234-41.
46. Albelda SM. Endothelial and epithelial cell adhesion molecules. Am J Respir Cell Mol Biol 1991; 4: 195-203.
47. Saetta M, Di Stefano A, Maestrelli P et al. Airway cosinophilia in chronic bronchitis during exacerbations. Am J Respir Crit Care Med 1994; 150: 1646-52.
48. Gordon JR, Galli SJ. Mast cells as a source of both preformed and immunologically inducible TNFα/cachectin. Nature 1990; 346: 274-6.
49. Walker C, Bauer W, Braun RK et al. Activated T cells and cytokines in bronchoalveolar lavage from patients with various lung diseases associated with eosinophilia. Am J Respir Crit Care Med 1994; 150: 1038-48.
50. Hamid Q, Azzawi M, Ying S et al. Expression of mRNA for interleukin-5 in mucosal bronchial biopsies from asthma. J Clin Invest 1991; 87: 1541-6.
51. Schall TJ, Bacon KB. Chemokines, leukocyte trafficking, and inflammation. Curr Opin Immunol 1994; 6: 865-73.
52. Baggiolini M, Loetscher P, Moser B. Interleukin-8 and the chemokine family. Int J Immunopharmacol 1995; 17: 103-8.