Chronic low dose risperidone and clozapine alleviate positive but not negative symptoms in the rat neonatal ventral hippocampal lesion model of schizophrenia

Psychopharmacology

Volumn 176, Issue 3-4, 2004, Pages 312-319

  Rueter, Lynne E ^a   Ballard, Michael E ^a   Gallagher, Kelly B ^a   Basso, Ana Maria ^a   Curzon, Peter ^a   Kohlhaas, Kathy L ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

Antipsychotic; Locomotor hyperactivity; Neurodevelopmental model; Prepulse inhibition; Schizophrenia; Social interaction

Indexed keywords

CLOZAPINE; NEUROLEPTIC AGENT; RISPERIDONE;

AGITATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN INJURY; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; DRUG RESPONSE; EXPERIMENTAL MODEL; FEMALE; HIPPOCAMPUS; HYPERACTIVITY; LONG TERM CARE; NEWBORN; NONHUMAN; PHARMACODYNAMICS; PREPULSE INHIBITION; PRIORITY JOURNAL; RAT; SCHIZOPHRENIA; SOCIAL INTERACTION; STARTLE REFLEX; SYMPTOM;

ACOUSTIC STIMULATION; ANIMALS; ANIMALS, NEWBORN; ANTIPSYCHOTIC AGENTS; BEHAVIOR, ANIMAL; CLOZAPINE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HIPPOCAMPUS; MALE; MOTOR ACTIVITY; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, DOPAMINE D2; RISPERIDONE; SCHIZOPHRENIC PSYCHOLOGY; SOCIAL BEHAVIOR; STARTLE REACTION;

EID: 10944251314     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00213-004-1897-4     Document Type: Article

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