Nature and nurture interplay: Schizophrenia

Psychiatrische Praxis, Supplement

Volumn 31, Issue 2, 2004, Pages

  McGuffin, Peter ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADOPTION; ALLELE; DISEASE TRANSMISSION; EMOTIONAL STABILITY; ENVIRONMENTAL FACTOR; EPIDEMIOLOGICAL DATA; EPIGENETICS; FAMILY STUDY; GENE FUNCTION; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENE MAPPING; GENE REPLICATION; GENETIC EPIDEMIOLOGY; GENETIC LINKAGE; GENETIC MARKER; GENETIC POLYMORPHISM; GENETIC RISK; GENETIC SUSCEPTIBILITY; HEREDITY; HUMAN; INHERITANCE; LIFE EVENT; LINKAGE ANALYSIS; NEUROBIOLOGY; PATHOPHYSIOLOGY; REVIEW; RISK FACTOR; SCHIZOPHRENIA; SMOKING; SOCIAL PROBLEM; TWINS;

EID: 10844241479     PISSN: 16118332     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2004-834565     Document Type: Review

References (36)

1. Gottesman II, Shields J. The Epigenetic Puzzle. Cambridge: Cambridge University Press, 1982
2. Gottesman II, Shields J. Schizophrenia, a think study vantage point. London: Academic Press, 1972
3. McGuffin P, Farmer AE, Gottesman II, Murray RM, Reveley AM. Twin concordance for operationally defined schizophrenia: Confirmation of familiality and heritability. Arch Gen Psychiatry 1984; 41: 541-545
4. Farmer AE, McGuffin P, Gottesman II. Twin concordance for DSM-III schizophrenia: Scrutinising the validity of the definition. Arch Gen Psychiatry 1987; 44: 634-641
5. Cardno AG, Marshall EJ, Coid B, Macdonald AM, Ribchester TR, Davies NJ, Venturi P, Jones LA, Lewis SW, Sham PC, Gottesman II, Farmer AE, McGuffin P, Reveley AM, Murray RM. Heritability estimates for psychotic disorders: the Maudsley twin psychosis series. Arch Gen Psychiatry 1999; 56 (2): 162-168
6. Cardno AG, Gottesman II. Twin studies of schizophrenia: from bow-and-arrow concordances to Star Wars Mx and functional genomics. American Journal of Medical Genetics (Semin Med Genet) 2000; 97 (12): 12-17
7. Wender PH, Rosenthal D, Kety SS, Schulsinger F, Weiner J. Social class and psychopathology in adoptees. A natural experimental method for separating the roles of genetic and experimential factors. Arch Gen Psychiatry 1973; 28 (3): 318-325
8. Kety SS, Rosenthal D, Wender PH, Schulsinger F, Jacobsen B. Mental illness in the biological and adoptive families of adopted individuals who have become schizophrenic. Behaviour Genetics 1976; 6: 219-225
9. Kendler KS, Gruenberg AM. An independent analysis of the Danish Adoption Study of Schizophrenia. VI. The relationship between psychiatric disorders as defined by DSM-III in the relatives and adoptees. Arch Gen Psychiatry 1984; 41 (6): 555-564
10. Kendler KS, Gruenberg AM, Kinney DK. Independent diagnoses of adoptees and relatives as defined by DSM-III in the provincial and national samples of the Danish Adoption Study of Schizophrenia. Arch Gen Psychiatry 1994; 51 (6): 456-468
11. Tienari P, Wynne LC, Sorri A, Lahti I, Laksy K, Moring J, Naarala M, Nieminen P, Wahlberg KE. Genotype-environment interaction in schizophrenia-spectrum disorder. Long-term follow-up study of Finnish adoptees. Br J Psychiatry 2004; 184: 216-222
12. Wetterberg L, Farmer AE. Clinical polydiagnostic studies in a large Swedish pedigree with schizophrenia. European Archives of Psychiatry and Clinical Neuroscience 1991; 240(3): 188-190
13. McGuffin P, Huckle P. Simulation of Mendelism revisted: the recessive gene for attending Medical School. Am J Hum Gen 1990; 46: 994-999
14. McGue M, Gottesman II. The genetic epidemiology of schizophrenia and the design of linkage studies. Eur Arch Psychiatry and Clin Neuroscience 1991; 240(3): 174-181
15. Falconer DS. The inheritance of liability to certain diseases, estimated from the incidence among relatives. Annals of Human Genetics 1965; 29: 51-76
16. Gottesman II, Shields J. A polygenic theory of schizophrenia. Procedures of the National Academy of Science USA 1967; 58: 199-205
17. Reich T, James JW, Morris CA. The use of multiple thresholds in determining the mode of transmission of semi-continuous traits. Ann Hum Genetics 1972; 36: 163-184
18. McGuffin P, Asherson P, Owen M, Farmer AE. The strength of the genetic effect - is there room for an evironmental influence in the aetiology of schizophrenia? Br J Psychiatry 1994; 164: 593-599
19. Murray RM, Sham P, Os J Van, Zanelli J, Cannon M, McDonald C. A developmental model for similarities and dissimilarities between schizophrenia and bipolar disorder. Schizophrenia Research 2004; 71 (2-3): 405-416
20. Brown AS, Hooton J, Schaefer CA, Zhang H, Petkova E, Babulas V, Perrin M, Gorman JM, Susser ES. Elevated maternal interleukin-8 levels and risk of schizophrenia in adult offspring. Am J Psychiatry 2004; 161 (5): 889-895
21. Mortensen PB, Pedersen CB, Westergaard T, Wohlfahrt J, Ewald H, Mors O, Andersen PK, Melbye M. Effects of family history and place and season of birth on the risk of schizophrenia. New England Journal of Medicine 1999; 340 (8): 603-608
22. McGuffin P, Gottesman II. Risk factors for schizophrenia. The New England Journal of Medicine 1999; 341 (5): 370-371
23. nd ed). Oxford: Blackwell, 2003: 611-634
24. Thapar A, Harold G, McGuffin P. Life events and depressive symptoms in childhood - shared genes or shared adversity? A research note. Journal of Child Psychology and Psychiatry 1998; 39 (8): 1153-1158
25. Farmer A, Harris T, Redman K, Sadler S, Mahmood A, McGuffin P. The Cardiff Depression Study - A sib pair study of life events and familiality in major depression. Br J Psychiatry 2000; 176: 150-155
26. Williams NM, Rees MI, Holmans P, Norton N, Cardno AG, Jones LA, Murphy KC, Sanders RD, McCarthy G, Gray MY, Fenton I, McGuffin P, Owen MJ. A two-stage genome scan for schizophrenia susceptibility genes in 196 affected sibling pairs. Human Molecular Genetics 1999; 8 (9): 729-1739
27. Gottesman II. Schizophrenia Genesis. New York: W. H. Freeman, 1991
28. Badner JA, Gershon ES. Meta-analysis of whole-genome linkage scans of bipolar disorder and schizophrenia. Mol Psychiatry 2002; 7 (4): 405-411
29. Lewis CM, Levinson DF, Wise LH, DeLisi LE, Straub RE, Hovatta I, Williams NM, Schwab SG, Pulver AE, Faraone SV, Brzustowicz LM, Kaufmann CA, Garver DL, Gurling HM, Lindholm E, Coon H, Moises HW, Byerley W, Shaw SH, Mesen A, Sherrington R, O'Neill FA, Walsh D, Kendler KS, Ekelund J, Paunio T, Lonnqvist J, Peltonen L, O'Donovan MC, Owen MJ, Wildenauer DB, Maier W, Nestadt G, Blouin JL, Antonarakis SE, Mowry BJ, Silverman JM, Crowe RR, Cloninger CR, Tsuang MT, Malaspina D, Harkavy-Friedman JM, Svrakic DM, Bassett AS, Holcomb J, Kalsi G, McQuillin A, Brynjolfson J, Sigmundsson T, Petursson H, Jazin E, Zoega T, Helgason T. Genome scan meta-analysis of schizophrenia and bipolar disorder. Part II: Schizophrenia. American Journal of Human Genetics, Epub 2003 Jun 11; 73: 34-48
30. Harrison P, Owen M. Genes for schizophrenia? Recent findings and their pathophysiological implications. Lancet 2003; 361: 417-419
31. McGuffin P, Tandon K, Corsico A. Linkage and association studies of schizophrenia. Curr Psychiatry Reports 2203; 5: 121-127
32. Moises HW, Zoega T, Gottesman II. The glial growth factors deficiency and synaptic destabilization hypothesis of schizophrenia. BMC Psychiatry 2002; 2 (1): 8
33. Caspi A, McClay J, Moffitt TE, Mill J, Martin J, Craig IW, Taylor A, Poulton R. Role of genotype in the cycle of violence in maltreated children. Science 2002; 297 (5582): 851-854
34. Foley DL, Eaves LJ, Wormley B, Silberg JL, Maes HH, Kuhn J, Riley B. Childhood adversity, monoamine oxidase a genotype, and risk for conduct disorder. Arch Gen Psychiatry 2004; 61 (7): 738-744
35. Caspi A, Sugden K, Moffitt TE, Taylor A, Craig IW, Harrington H, McClay J, Mill J, Martin J, Braithwaite A, Poulton R. Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. Science 2003; 301 (5631): 386-389
36. Eley T, Sugden K, Corsico A, Gregory A, Sham P, McGuffin P, Plomin R, Craig I. Gene-environment interaction analysis of serotonin system markers with adolescent depression. Mol Psychiatry 2004; 9: 908-915