메뉴 건너뛰기




Volumn 14, Issue 11, 2003, Pages 733-747

A strategy for the integration of QTL, gene expression, and sequence analyses

Author keywords

[No Author keywords available]

Indexed keywords

NUCLEOTIDE; TRANSCRIPTION FACTOR;

EID: 10744232721     PISSN: 09388990     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00335-003-2277-9     Document Type: Article
Times cited : (69)

References (44)
  • 1
    • 0032958470 scopus 로고    scopus 로고
    • Identification of Cd36 (Fat) as an insulin-resistance gene causing defective fatty acid and glucose metabolism in hypertensive rats
    • Aitman TJ, Glazier AM, Wallace CA, Cooper LD, Northsworthy PJ et al. (1999) Identification of Cd36 (Fat) as an insulin-resistance gene causing defective fatty acid and glucose metabolism in hypertensive rats. Nat Gen 21, 76-83
    • (1999) Nat Gen , vol.21 , pp. 76-83
    • Aitman, T.J.1    Glazier, A.M.2    Wallace, C.A.3    Cooper, L.D.4    Northsworthy, P.J.5
  • 2
    • 0029878553 scopus 로고    scopus 로고
    • Type I and type II error rates for quantitative trait loci (QTL) mapping studies using recombination inbred mouse strains
    • Belknap JK, Mitchellm SR, O'Toole LA, Helms ML, Crabbe JC (1996) Type I and type II error rates for quantitative trait loci (QTL) mapping studies using recombination inbred mouse strains. Behav Genet 26, 149-160
    • (1996) Behav Genet , vol.26 , pp. 149-160
    • Belknap, J.K.1    Mitchellm, S.R.2    O'Toole, L.A.3    Helms, M.L.4    Crabbe, J.C.5
  • 3
    • 0034891003 scopus 로고    scopus 로고
    • QTL analysis and genome wide mutagenesis in mice: Complementary genetic approaches to the dissection of complex traits
    • Belknap JK, Hitzemann R, Crabbe JC, Phillips TJ, Buck KJ et al. (2001) QTL analysis and genome wide mutagenesis in mice: complementary genetic approaches to the dissection of complex traits. Behav Genet 31, 5-15
    • (2001) Behav Genet , vol.31 , pp. 5-15
    • Belknap, J.K.1    Hitzemann, R.2    Crabbe, J.C.3    Phillips, T.J.4    Buck, K.J.5
  • 4
    • 0034820774 scopus 로고    scopus 로고
    • Chipping away at complex behavior: Transcriptome/phenotype correlations in the mouse brain
    • Carter TA, Del Rio JA, Greenhall JA, Latronica ML et al. (2001) Chipping away at complex behavior: transcriptome/phenotype correlations in the mouse brain. Physiol Behav 73, 849-857
    • (2001) Physiol Behav , vol.73 , pp. 849-857
    • Carter, T.A.1    Del Rio, J.A.2    Greenhall, J.A.3    Latronica, M.L.4
  • 6
    • 0028151261 scopus 로고
    • Empirical thresholds for quantitative trait mapping
    • Churchill GA, Doerge RW (1994) Empirical thresholds for quantitative trait mapping. Genetics 138, 963-971
    • (1994) Genetics , vol.138 , pp. 963-971
    • Churchill, G.A.1    Doerge, R.W.2
  • 7
    • 0033650366 scopus 로고    scopus 로고
    • Cd36 and molecular mechanisms of insulin resistance in the stroke-prone spontaneously hypertensive rat
    • Collison M, Glazier AM, Graham D, Morton JJ, Dominiczak MH et al. (2000) Cd36 and molecular mechanisms of insulin resistance in the stroke-prone spontaneously hypertensive rat. Diabetes 49, 2222-2226
    • (2000) Diabetes , vol.49 , pp. 2222-2226
    • Collison, M.1    Glazier, A.M.2    Graham, D.3    Morton, J.J.4    Dominiczak, M.H.5
  • 8
  • 9
    • 0031975307 scopus 로고    scopus 로고
    • Experimental strategies for the genetic dissection of complex traits in animal models
    • Darvasi A (1998) Experimental strategies for the genetic dissection of complex traits in animal models. Nat Genet 18, 19-24
    • (1998) Nat Genet , vol.18 , pp. 19-24
    • Darvasi, A.1
  • 10
    • 0034892647 scopus 로고    scopus 로고
    • Further characterization and high-resolution mapping of quantitative trait loci for ethanol-induced locomotor activity
    • Demarest K, Koyner J, McCaughran J, Cipp L, Hitzemann R (2001) Further characterization and high-resolution mapping of quantitative trait loci for ethanol-induced locomotor activity. Behav Genet 31, 79-91
    • (2001) Behav Genet , vol.31 , pp. 79-91
    • Demarest, K.1    Koyner, J.2    McCaughran, J.3    Cipp, L.4    Hitzemann, R.5
  • 11
    • 0026645062 scopus 로고
    • A genetic map of the mouse suitable for typing intraspecific crosses
    • Dietrich W, Katz H, Lincoln SE, Shin H, Friedman J et al. (1992) A genetic map of the mouse suitable for typing intraspecific crosses. Genetics 131, 423-447
    • (1992) Genetics , vol.131 , pp. 423-447
    • Dietrich, W.1    Katz, H.2    Lincoln, S.E.3    Shin, H.4    Friedman, J.5
  • 12
    • 0028302127 scopus 로고
    • A genetic map of the mouse with 4,006 simple sequence polymorphisms
    • Dietrich WF, Miller JC, Steen RG et al. (1994) A genetic map of the mouse with 4,006 simple sequence polymorphisms. Nat Genet 7, 220-245
    • (1994) Nat Genet , vol.7 , pp. 220-245
    • Dietrich, W.F.1    Miller, J.C.2    Steen, R.G.3
  • 13
    • 13344287050 scopus 로고    scopus 로고
    • A comprehensive genetic map of the mouse genome
    • Dietrich WF, Miller J, Steen R et al. (1996) A comprehensive genetic map of the mouse genome. Nature 380, 149-152
    • (1996) Nature , vol.380 , pp. 149-152
    • Dietrich, W.F.1    Miller, J.2    Steen, R.3
  • 14
    • 0034964492 scopus 로고    scopus 로고
    • Quantitative genetic study of maximal electroshock seizure threshold in mice: Evidence for a motor seizure susceptibility locus on distal Chromosome 1
    • Ferraro TN, Golden GT, Smith GG, Longman RL, Snyder RL et al. (2001) Quantitative genetic study of maximal electroshock seizure threshold in mice: evidence for a motor seizure susceptibility locus on distal Chromosome 1. Genomics 75, 35-42
    • (2001) Genomics , vol.75 , pp. 35-42
    • Ferraro, T.N.1    Golden, G.T.2    Smith, G.G.3    Longman, R.L.4    Snyder, R.L.5
  • 15
    • 0037222985 scopus 로고    scopus 로고
    • The analysis of quantitative trait loci that influence animal behavior
    • in press
    • Flint J (2003) The analysis of quantitative trait loci that influence animal behavior. J Neurobiol in press
    • (2003) J Neurobiol
    • Flint, J.1
  • 16
    • 0035380102 scopus 로고    scopus 로고
    • Finding the molecular basis of quantitative traits: Successes and pitfalls
    • Flint J, Mott R (2001) Finding the molecular basis of quantitative traits: Successes and pitfalls. Nat Rev Genet 2, 437-445
    • (2001) Nat Rev Genet , vol.2 , pp. 437-445
    • Flint, J.1    Mott, R.2
  • 17
    • 0029084912 scopus 로고
    • A simple genetic basis for a complex psychological trait in laboratory mice
    • Flint J, Corley R, DeFries JC, Fulker DW, Gray JA et al. (1995) A simple genetic basis for a complex psychological trait in laboratory mice. Science 269, 1432-1435
    • (1995) Science , vol.269 , pp. 1432-1435
    • Flint, J.1    Corley, R.2    DeFries, J.C.3    Fulker, D.W.4    Gray, J.A.5
  • 19
    • 0034718546 scopus 로고    scopus 로고
    • Mice, microarrays, and the genetic diversity of the brain
    • Geschwind DH (2000) Mice, microarrays, and the genetic diversity of the brain. Proc Natl Acad Sci USA 97, 10676-10678
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 10676-10678
    • Geschwind, D.H.1
  • 20
    • 0035827344 scopus 로고    scopus 로고
    • In silco mapping of complex disease-related traits in mice
    • Grupe A, Germer S, Usuka J, Usuka J et al. (2001) In silco mapping of complex disease-related traits in mice. Science 292, 1915-1918
    • (2001) Science , vol.292 , pp. 1915-1918
    • Grupe, A.1    Germer, S.2    Usuka, J.3    Usuka, J.4
  • 21
    • 0032806262 scopus 로고    scopus 로고
    • Chlordiazepoxide-induced expression of c-Fos in the central extended a-mygdala and other brain regions of the C57BL/6J and DBA/2J inbred mouse strains: Relationships to the mechanisms of ethanol action
    • Hitzemann B, Hitzemann R (1997) Chlordiazepoxide-induced expression of c-Fos in the central extended a-mygdala and other brain regions of the C57BL/6J and DBA/2J inbred mouse strains: relationships to the mechanisms of ethanol action. Alcohol Clin Exp Res 23, 1158-1172
    • (1997) Alcohol Clin Exp Res , vol.23 , pp. 1158-1172
    • Hitzemann, B.1    Hitzemann, R.2
  • 22
    • 0030657781 scopus 로고    scopus 로고
    • Genetics, ethanol and the Fos response: A comparison of the C57BL/6J and DBA/2J inbred mouse strains
    • Hitzemann B, Hitzemann R (1999) Genetics, ethanol and the Fos response: a comparison of the C57BL/6J and DBA/2J inbred mouse strains. Alcohol Clin Exp Res 21, 1497-1507
    • (1999) Alcohol Clin Exp Res , vol.21 , pp. 1497-1507
    • Hitzemann, B.1    Hitzemann, R.2
  • 23
    • 0034484840 scopus 로고    scopus 로고
    • Effects of genetic cross on the detection of quantitative trait loci and a novel approach to mapping QTLs
    • Hitzemann R, Demarest K, Koyner J, Cipp L, Patel N et al. (2000) Effects of genetic cross on the detection of quantitative trait loci and a novel approach to mapping QTLs. Pharmacol Biochem Behav 67, 767-772
    • (2000) Pharmacol Biochem Behav , vol.67 , pp. 767-772
    • Hitzemann, R.1    Demarest, K.2    Koyner, J.3    Cipp, L.4    Patel, N.5
  • 24
    • 0037836126 scopus 로고    scopus 로고
    • Multiple cross mapping (MCM) markedly improves the localization of a QTL for ethanol-induced activation
    • Hitzemann R, Malmanger B, Cooper S, Coulombe S, Reed et al. (2002) Multiple cross mapping (MCM) markedly improves the localization of a QTL for ethanol-induced activation. Genes Brain Behav 1, 214-222
    • (2002) Genes Brain Behav , vol.1 , pp. 214-222
    • Hitzemann, R.1    Malmanger, B.2    Cooper, S.3    Coulombe, S.4    Reed5
  • 25
    • 0027331482 scopus 로고
    • On the relationship between DZ receptor density and neuroleptic-induced catalepsy among eight inbred strains of mice
    • Kanes SJ, Hitzemann BA, Hitzemann RJ (1993) On the relationship between DZ receptor density and neuroleptic-induced catalepsy among eight inbred strains of mice. J Pharmacol Exp Ther 267, 538-547
    • (1993) J Pharmacol Exp Ther , vol.267 , pp. 538-547
    • Kanes, S.J.1    Hitzemann, B.A.2    Hitzemann, R.J.3
  • 26
    • 5944254200 scopus 로고    scopus 로고
    • Identification of complement factor 5 as a susceptibility locus for experimental allergic asthma
    • Karp CL, Grupe A, Schadt E, Ewart SL et al. (2000) Identification of complement factor 5 as a susceptibility locus for experimental allergic asthma. Nat Immunol 1, 221-226
    • (2000) Nat Immunol , vol.1 , pp. 221-226
    • Karp, C.L.1    Grupe, A.2    Schadt, E.3    Ewart, S.L.4
  • 27
    • 0033730411 scopus 로고    scopus 로고
    • Identification and time dependence of quantitative trait loci for basal locomotor activity in the BXD recombinant inbred series and a B6D2 F2 intercross
    • Koyner J, Demarest K, McCaughran J, Cipp L, Hitzemann R (2000) Identification and time dependence of quantitative trait loci for basal locomotor activity in the BXD recombinant inbred series and a B6D2 F2 intercross. Behav Genet 30, 159-170
    • (2000) Behav Genet , vol.30 , pp. 159-170
    • Koyner, J.1    Demarest, K.2    McCaughran, J.3    Cipp, L.4    Hitzemann, R.5
  • 28
    • 0028877463 scopus 로고
    • Genetic dissection of complex traits: Guidelines for interpreting and reporting linkage results
    • Lander E, Kruglyak L (1995) Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. Nat Genet 11, 241-247
    • (1995) Nat Genet , vol.11 , pp. 241-247
    • Lander, E.1    Kruglyak, L.2
  • 29
    • 0035222137 scopus 로고    scopus 로고
    • Expressing what's on your mind: DNA arrays and the brain
    • Lockhart DJ, Barlow C (2001) Expressing what's on your mind: DNA arrays and the brain. Nat Rev Neurosci 2, 63-68
    • (2001) Nat Rev Neurosci , vol.2 , pp. 63-68
    • Lockhart, D.J.1    Barlow, C.2
  • 30
    • 0035671407 scopus 로고    scopus 로고
    • The genetic architecture of quantitative traits
    • Mackay TF (2001) The genetic architecture of quantitative traits. Annu Rev Genet 35, 303-339
    • (2001) Annu Rev Genet , vol.35 , pp. 303-339
    • Mackay, T.F.1
  • 31
    • 0028913620 scopus 로고
    • Ethanol-induced anesthesia in inbred strains of long-sleep and short-sleep mice: A genetic analysis of repeated measures using censored data
    • Markel PD, DeFries JC, Johnson TE (1995) Ethanol-induced anesthesia in inbred strains of long-sleep and short-sleep mice: a genetic analysis of repeated measures using censored data. Behav Genet 25, 67-73
    • (1995) Behav Genet , vol.25 , pp. 67-73
    • Markel, P.D.1    DeFries, J.C.2    Johnson, T.E.3
  • 32
    • 0038652120 scopus 로고    scopus 로고
    • In silico discovery of gene-coding variants in murine quantitative trait loci using strain-specific genome sequence databases
    • RESEARCH 0078
    • Marshall KE, Godden EL, Yang F, Burgers S, Buck KJ et al. (2002) In silico discovery of gene-coding variants in murine quantitative trait loci using strain-specific genome sequence databases. Genome Biol 3, RESEARCH 0078.
    • (2002) Genome Biol , vol.3
    • Marshall, K.E.1    Godden, E.L.2    Yang, F.3    Burgers, S.4    Buck, K.J.5
  • 35
    • 0242287052 scopus 로고    scopus 로고
    • Statistical methods for identifying differentially expressed genes in DNA microarrays
    • Storey JD, Tibshirani R (2003) Statistical methods for identifying differentially expressed genes in DNA microarrays. Methods Mol Biol 224, 149-157
    • (2003) Methods Mol Biol , vol.224 , pp. 149-157
    • Storey, J.D.1    Tibshirani, R.2
  • 36
    • 0032979854 scopus 로고    scopus 로고
    • High resolution mapping of quantitative trait loci in outbred mice
    • Talbot CJ, Nicod A, Cherny SS, Fulker DW, Collins AC et al. (1999) High resolution mapping of quantitative trait loci in outbred mice. Nat Genet 21, 305-308
    • (1999) Nat Genet , vol.21 , pp. 305-308
    • Talbot, C.J.1    Nicod, A.2    Cherny, S.S.3    Fulker, D.W.4    Collins, A.C.5
  • 38
    • 0027275089 scopus 로고
    • A new strain congenic for the Mtv-7/Mls-1 locus of mouse Chromosome 1
    • Taylor BA, Frankel WN (1993) A new strain congenic for the Mtv-7/Mls-1 locus of mouse Chromosome 1. Immunogenetics 38, 235-237
    • (1993) Immunogenetics , vol.38 , pp. 235-237
    • Taylor, B.A.1    Frankel, W.N.2
  • 40
    • 0037028155 scopus 로고    scopus 로고
    • The mosaic structure of variation in the laboratory mouse genome
    • Wade CM, Kulbokas EJ, Kirby AW, Zody MC, Mullikin JC et al. (2002) The mosaic structure of variation in the laboratory mouse genome. Nature 420, 574-578
    • (2002) Nature , vol.420 , pp. 574-578
    • Wade, C.M.1    Kulbokas, E.J.2    Kirby, A.W.3    Zody, M.C.4    Mullikin, J.C.5
  • 41
    • 0037069380 scopus 로고    scopus 로고
    • Combining mapping and arraying: An approach to candidate gene identification
    • Wayne ML, McIntyre LM (2002) Combining mapping and arraying: an approach to candidate gene identification. Proc Natl Acad Sci USA 99, 14903-14906
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 14903-14906
    • Wayne, M.L.1    McIntyre, L.M.2
  • 43
    • 0036146465 scopus 로고    scopus 로고
    • Gene coding variant in Cas1 between the C57BL/6J and DBA/2J inbred mouse strains: Linkage to a QTL for ethanol-induced locomotor activation
    • Xu Y, Demarest K, Hitzemann R, Sikela JM (2002) Gene coding variant in Cas1 between the C57BL/6J and DBA/2J inbred mouse strains: linkage to a QTL for ethanol-induced locomotor activation. Alcohol Clin Exp Res 26, 1-7
    • (2002) Alcohol Clin Exp Res , vol.26 , pp. 1-7
    • Xu, Y.1    Demarest, K.2    Hitzemann, R.3    Sikela, J.M.4
  • 44
    • 0036252319 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor 4 is a target for the zinc-finger transcription factor Ikaros in the pituatary
    • Yu S, Asa SL, Ezzat S (2002) Fibroblast growth factor receptor 4 is a target for the zinc-finger transcription factor Ikaros in the pituatary. Mol Endocrinol 16, 1069-1078
    • (2002) Mol Endocrinol , vol.16 , pp. 1069-1078
    • Yu, S.1    Asa, S.L.2    Ezzat, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.