Combination of DNA repair gene single nucleotide polymorphisms and increased levels of DNA adducts in a population-based study

Cancer Epidemiology Biomarkers and Prevention

Volumn 12, Issue 7, 2003, Pages 674-677

  Matullo, Giuseppe ^a,b   Peluso, Marco ^d   Polidoro, Silvia ^a   Guarrera, Simonetta ^a   Munnia, Armelle ^d   Krogh, Vittorio ^c   Masala, Giovanna ^d   Berrino, Franco ^c   Panico, Salvatore ^e   Tumino, Rosario ^f   Vineis, Paolo ^a,b   Palli, Domenico ^d  

^a UNIVERSITY OF TURIN   (Italy)

^b ISI FOUNDATION   (Italy)

^c NATIONAL CANCER INSTITUTE   (Italy)

^d CANCER RESEARCH AND PREVENTION INSTITUTE ISPO   (Italy)

^e UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^f CIVILE M P AREZZO HOSPITAL   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; NUCLEASE; NUCLEOTIDE; PHOSPHORUS 32;

ADULT; ARTICLE; CANCER SUSCEPTIBILITY; CONTROLLED STUDY; DNA ADDUCT; DNA REPAIR; FEMALE; GENE FREQUENCY; GENOTYPE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; ITALY; LEUKOCYTE; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE ANALYSIS; POLYMERASE CHAIN REACTION; POPULATION RESEARCH; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SINGLE NUCLEOTIDE POLYMORPHISM; XERODERMA PIGMENTOSUM;

ALLELES; ANALYSIS OF VARIANCE; DNA ADDUCTS; DNA REPAIR; HUMANS; ITALY; LEUKOCYTES; NEOPLASMS; ODDS RATIO; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; POLYMORPHISM, SINGLE NUCLEOTIDE; PROSPECTIVE STUDIES; SEQUENCE ANALYSIS, DNA; XERODERMA PIGMENTOSUM;

EID: 10744225286     PISSN: 10559965     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. Berwick, M., and Vineis, P. Markers of DNA repair and susceptibility to cancer in humans: an epidemiologic review. J. Natl. Cancer Inst. (Bethesda), 92: 874-897, 2000.
2. Mohrenweiser, H. W., and Jones, I. M. Variation in DNA repair is a factor in cancer susceptibility: a paradigm for the promises and perils of individual and population risk estimation? Mutat. Res., 400: 15-24, 1998.
3. Friedberg, E. C., Walker, G. C., and Siede, W. (eds.). DNA Repair and Mutagenesis. Washington, DC: ASM Press, 1995.
4. Sancar, A. DNA repair in human. Annu. Rev. Genet., 29: 69-105, 1995.
5. Shen, M. R., Jones, I. M., and Mohrenweiser, H. Nonconservative amino acid substitution variants exist at polymorphic frequency in DNA repair genes in healthy humans. Cancer Res., 58: 604-608, 1998.
6. Qiao, Y., Spitz, M. R., Shen, H., Guo, Z., Shete, S., Hedayati, M., Grossman, L., Mohrenweiser, H., and Wie, Q. Modulation of repair of ultraviolet damage in the host-cell reactivation assay by polymorphic XPC and XPD/ERCC2 genotypes. Carcinogenesis (Lond.), 23: 295-299, 2002.
7. Zhou, W., Liu, G., Miller, D. P., Thurston, S. W., Xu, L. L., Wain, J. C., Lynch, T. J., Su, L., and Christiani, D. C. Gene-environment interaction for the ERCC2 polymorphisms and cumulative cigarette smoking exposure in lung cancer. Cancer Res., 62: 1377-1381, 2002.
8. Spitz, M. R., Wu, X., Wang, Y., Wang, L. E., Shete, S., Amos, C. I., Guo, Z., Lei, L., Mohrenweiser, H., and Wei, Q. Modulation of nucleotide excision repair capacity by XPD polymorphisms in lung cancer patients. Cancer Res., 61: 1354-1357, 2001.
9. Seker, H., Butkiewicz, D., Bowman, E. D., Rusin, M., Hedayati, M., Grossman, L., and Harris, C. C. Functional significance of XPD polymorphic variants: attenuated apoptosis in human lymphoblastoid cells with the XPD 312 Asp/Asp genotype. Cancer Res., 61: 7430-7434, 2001.
10. 32P-DNA adducts in a sample of healthy subjects. Carcinogenesis (Lond.), 22: 1437-1445, 2001.
11. Palli, D., Vineis, P., Russo, A., Berrino, F., Krogh, V., Masala, G., Munnia, A., Panico, S., Taioli, E., Tumino, R., Garte, S., and Peluso, M. Diet, metabolic polymorphisms and DNA adducts: the EPIC-Italy cross-sectional study. Int. J. Cancer, 87: 444-451, 2000.
12. Berwick, M., Matullo, G., and Vineis, P. Studies of DNA repair and human cancer: an update. In: S. H. Wilson and W. A. Suk (eds.), Biomarkers of Environmentally-Associated Diseases: Technologies, Concepts, and Perspectives, pp. 83-107. Boca Raton, FL: CRC Press, 2002.
13. Wiencke, J. K. DNA adduct burden and tobacco carcinogenesis. Oncogene, 21: 7376-7391, 2002.
14. Tang, D., Cho, S., Rundle, A., Chen, S., Phillips, D., Zhou, J., Hsu, Y., Schnabel, F., Estabrook, A., and Perera, F. P. Polymorphisms in the DNA repair enzyme XPD are associated with increased levels of PAH-DNA adducts in a case-control study of breast cancer. Breast Cancer Res. Treat., 75: 159-166, 2002.
15. Pastorelli, R., Cerri, A., Mezzetti, M., Consonni, E., and Airoldi, L. Effect of DNA repair gene polymorphisms on BPDE-DNA adducts in human lymphocytes. Int. J. Cancer, 100: 9-13, 2002.
16. Matullo, G., Guarrera, S., Carturan, S., Peluso, M., Malaveille, C., Davico, L., Piazza, A., and Vineis, P. DNA repair gene polymorphisms, bulky DNA adducts in white blood cells and bladder cancer in a case-control study. Int. J. Cancer, 92: 562-567, 2001.
17. Riboli, E., and Kaaks, R. The EPIC Project: rationale and study design. Int. J. Epidemiol., 26 (Suppl. 1): S6-S14, 1997.
18. Winsey, S. L., Haldar, N. A., Marsh, H. P., Bunce, M., Marshall, S. E., Harris, A. L., Wojnarowska, F., and Welsh, K. I. A variant within the DNA repair gene XRCC3 is associated with the development of melanoma skin cancer. Cancer Res., 60: 5612-5616, 2000.
19. Lunn, R. M., Langlois, R. G., Hsieh, L. L., Thompson, C. L., and Bell, D. A. XRCC1 polymorphisms: effects on aflatoxin B1-DNA adducts and glycophorin A variant frequency. Cancer Res., 59: 2557-2561, 1999.
20. Broughton, B. C., Steingrimsdottir, H., and Lehmann, A. R. Five polymorphisms in the coding sequence of the xeroderma pigmentosum group D gene. Mutat. Res., 362: 209-211, 1996.
21. Duell, E. J., Wiencke, J. K., Cheng, T. J., Varkonyi, A., Zuo, Z. F., Ashok, T. D. S., Mark, E. J., Wain, J. C., Christiani, D. C., and Kelsey, K. T. Polymorphisms in the DNA repair genes XRCC1 and ERCC2 and biomarkers of DNA damage in human blood mononuclear cells. Carcinogenesis (Lond.), 21: 965-971, 2000.
22. Butkiewicz, D., Rusin, M., Enewold, L., Shields, P. G., Chorazy, M., and Harris, C. C. Genetic polymorphisms in DNA repair genes and risk of lung cancer. Carcinogenesis (Lond.), 22: 593-597, 2001.
23. 2P-postlabeling studies of air pollution. Am. J. Epidemiol., 153: 546-558, 2001.
24. 32P-postlabellig analysis of DNA adducted with urinary mutagens from smokers of black tobacco. Carcinogenesis (Lond.), 11: 1307-1311, 1990.
25. Palli, D., Russo, A., Masala, G., Saieva, C., Guarrera, S., Carturan, S., Munnia, A., Matullo, G., and Peluso, M. DNA adduct levels and DNA repair polymorphisms in traffic-exposed workers and a general population sample. Int. J. Cancer, 94: 121-127, 2001.
26. Hou, S. M., Falt, S., Angelini, S., Yang, K., Nyberg, F., Lambert, B., and Hemminki, K. The XPD variant alleles are associated with increased aromatic DNA adduct level and lung cancer risk. Carcinogenesis (Lond.), 23: 599-603, 2002.
27. Thompson, L. H., Brookman, K. W., Jones, N. J., Allen, S. A., and Carrano, A. V. Molecular cloning of the human XRCC1 gene, which corrects defective DNA strand break repair and sister chromatid exchange. Mol. Cell. Biol., 10: 6160-6171, 1990.
28. Tebbs, R. S., Zhao, Y., Tucker, J. D., Scheerer, J. B., Siciliano, M. J., Hwang, M., Liu, N., Legerski, R. J., and Thompson, L. H. Correction of chromosomal instability and sensitivity to diverse mutagens by a cloned cDNA of the XRCC3 DNA repair gene. Proc. Natl. Acad. Sci. USA, 92: 6354-6358, 1995.
29. Flejter, W. L., McDaniel, L. D., Johns, D., Friedberg, E. C., and Schultz, R. A. Correction of xeroderma pigmentosum complementation group D mutant cell phenotypes by chromosome and gene transfer: involvement of the human ERCC2 DNA repair gene. Proc. Natl. Acad. Sci. USA, 89: 261-265, 1992.
30. Braithwaite, E., Wu, X., and Wang, Z. Repair of DNA lesions induced by polycyclic aromatic hydrocarbons in human cell-free extracts: involvement of two excision repair mechanisms in vitro. Carcinogenesis (Lond.), 19: 1239-1246, 1998.
31. Hang, B., Chenna, A., Sagi, J., and Singer, B. Differential cleavage of oligonucleotides containing the benzene-derived adduct, 1, N6-benzetheno-dA, by the major human AP endonuclease HAP1 and Escherichia coli exonuclease III and endonuclease IV. Carcinogenesis, 19: 1339-1343, 1998.
32. Devanesan, P. D., Higginbotham, S., Ariese, F., Jankowiak, R., Suh, M., Small, G. J., Cavalieri, E. L., and Rogan, E. G. Depurinating and stable benzo[a]pyrene-DNA adducts formed in isolated rat liver nuclei. Chem. Res. Toxicol., 9: 1113-1116, 1996.
33. Chakravarti, D., Mailander, P. C., Cavalieri, E. L., and Rogan, E. G. Evidence that error-prone DNA repair converts dibenzo[a, 1]pyrene-induced depurinating lesions into mutations: formation, clonal proliferation and regression of initiated cells carrying H-ras oncogene mutations in early preneoplasia. Mutat. Res., 456: 17-32, 2000.
34. Randerath, K., Randerath, E., Smith, C. V., and Chang, J. Structural origins of bulky oxidative DNA adducts (type II I-compounds) as deduced by oxidation of oligonucleotides of known sequences. Chem. Res. Toxicol., 9: 247-254, 1996.
35. De Silva, I. U., McHugh, P. J., Clingen, P. H., and Hartley, J. A. Defining the roles of nucleotide excision repair and recombination in the repair of DNA interstrand cross-links in mammalian cells. Mol. Cell. Biol., 20: 7980-7990, 2000.
36. Araujo, F. D., Pierce, A. J., Stark, J. M., Jasin, M. Variant XRCC3 implicated in cancer is functional in homology-directed repair of double-strand breaks. Oncogene, 21: 4176-4180, 2002.
37. Stern, M. C., Umbach, D. M., Lunn, R. M., and Taylor, J. A. DNA repair gene XRCC3 codon 241 polymorphism, its interaction with smoking and XRCC1 polymorphisms, and bladder cancer risk. Cancer Epidemiol. Biomark. Prev., 11: 939-943, 2002.
38. Kuschel, B., Auranen, A., McBride, S., Novik, K. L., Antoniou, A., Lipscombe, J. M., Day, N. E., Easton, D. F., Ponder, B. A., Pharoah, P. D., and Dunning, A. Variants in DNA double-strand break repair genes and breast cancer susceptibility. Hum. Mol. Genet., 11: 1399-1407, 2002.