Detailed glycan analysis of serum glycoproteins of patients with congenital disorders of glycosylation indicates the specific defective glycan processing step and provides an insight into pathogenesis

Glycobiology

Volumn 13, Issue 9, 2003, Pages 601-622

  Butler, Michael ^a   Quelhas, D ^b   Critchley, Alison J ^a   Carchon, Hubert ^c   Hebestreit, Holger F ^a   Hibbert, Richard G ^a   Vilarinho, Laura ^b   Teles, E ^d   Matthijs, Gert ^e   Schollen, Els ^e   Argibay, Pablo ^a   Harvey, David J ^a   Dwek, Raymond A ^a   Jaeken, Jaak ^c   Rudd, Pauline M ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b NATIONAL INSTITUTE OF HEALTH DR RICARDO JORGE   (Portugal)

^c UNIVERSITY OF LEUVEN   (Belgium)

^d HOSPITAL DE SÃO JOÃO   (Portugal)

^e UNIVERSITY HOSPITALS LEUVEN   (Belgium)

Author keywords

CDGs; Glycosylation; IgG; Proteome; Transferrin

Indexed keywords

ACETYLGLUCOSAMINIDASE; GLYCAN; GLYCOPROTEIN; IMMUNOGLOBULIN G; MANNOSIDASE; PROTEOME; SUGAR; TRANSFERRIN;

ANTIBODY ISOLATION; ARTICLE; CARBOHYDRATE ANALYSIS; CELL SPECIFICITY; CELL TYPE; CLINICAL FEATURE; COMPLEMENT SYSTEM; CONGENITAL DISORDER; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE ACTIVITY; DISEASE CLASSIFICATION; DISEASE SEVERITY; ENZYME ACTIVITY; GENE MUTATION; HUMAN; METABOLIC DISORDER; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN GLYCOSYLATION; PROTEIN ISOLATION; PROTEIN PROCESSING;

CARBOHYDRATE METABOLISM, INBORN ERRORS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GLYCOPROTEINS; GLYCOSYLATION; HUMANS; HYDROGEN-ION CONCENTRATION; IMMUNOGLOBULIN G; MOLECULAR STRUCTURE; N-ACETYLGLUCOSAMINYLTRANSFERASES; POLYSACCHARIDES; PROTEIN ISOFORMS; PROTEOME; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TRANSFERRIN;

EID: 10744225031     PISSN: 09596658     EISSN: None     Source Type: Journal    
DOI: 10.1093/glycob/cwg079     Document Type: Article

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