Modeling human congenital disorder of glycosylation type IIa in the mouse: Conservation of asparagine-linked glycan-dependent functions in mammalian physiology and insights into disease pathogenesis

Glycobiology

Volumn 11, Issue 12, 2001, Pages 1051-1070

  Wang, Yan ^a   Tan, Jenny ^b   Sutton Smith, Mark ^c   Ditto, David ^d   Panico, Maria ^c   Campbell, Robert M ^a   Varki, Nissi M ^e   Long, Jeffrey M ^a,f,g   Jaeken, Jaak ^h   Levinson, Simon R ⁱ   Wynshaw Boris, Anthony ^a,f,g   Morris, Howard R ^c   Le, Dzung ^d   Dell, Anne ^c   Schachter, Harry ^b   Marth, Jamey D ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b HOSPITAL FOR SICK CHILDREN   (Canada)

^c IMPERIAL COLLEGE LONDON   (United Kingdom)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^f UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^g UNIVERSITY OF CALIFORNIA   (United States)

^h UNIVERSITY OF LEUVEN   (Belgium)

ⁱ UNIVERSITY OF COLORADO   (United States)

Author keywords

CDG IIa; Disease; Genetics; Glycosylation; N glycans

Indexed keywords

ASPARAGINE; GLYCAN; GLYCOSYLTRANSFERASE; LECTIN; N ACETYLGLUCOSAMINE; OLIGOSACCHARIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARBOHYDRATE SYNTHESIS; COMPLEX FORMATION; CONGENITAL DISORDER OF GLYCOSYLATION; CONTROLLED STUDY; DISEASE SEVERITY; ENZYME ACTIVITY; FEMALE; GASTROINTESTINAL DISEASE; GENE MUTATION; GENETIC DISORDER; GENETIC HETEROGENEITY; GOLGI COMPLEX; HEMATOLOGIC DISEASE; INBORN ERROR OF METABOLISM; MAMMAL; MOUSE; NONHUMAN; PATHOGENESIS; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; PROTEIN GLYCOSYLATION; SCREENING TEST; SPECIES DIFFERENCE;

ANIMALIA; MAMMALIA;

EID: 0035714138     PISSN: 09596658     EISSN: None     Source Type: Journal    
DOI: 10.1093/glycob/11.12.1051     Document Type: Article

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