Decreased Expression of p107 is Correlated with Anaplastic Transformation in Papillary Carcinoma of the Thyroid

Anticancer Research

Volumn 23, Issue 5 A, 2003, Pages 3819-3824

  Ito, Yasuhiro ^a   Yoshida, Hiroshi ^a   Tomoda, Chisato ^a   Uruno, Takashi ^a   Takamura, Yuuki ^a   Miya, Akihiro ^a   Kobayashi, Kaoru ^a   Matsuzuka, Fumio ^a   Kuma, Kanji ^a   Miyauchi, Akira ^a  

^a KUMA HOSPITAL   (Japan)

Author keywords

Immunohistochemistry; p107; Thyroid

Indexed keywords

POLYCLONAL ANTIBODY; PROTEIN P107;

ANAPLASTIC CARCINOMA; ARTICLE; CARCINOMA CELL; CELL TRANSFORMATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; FOLLICULAR CARCINOMA; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; OVARY FOLLICLE CELL; PAPILLARY CARCINOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; THYROID CARCINOMA; TISSUE SPECIFICITY;

CARCINOMA; CARCINOMA, PAPILLARY; CELL TRANSFORMATION, NEOPLASTIC; HUMANS; IMMUNOHISTOCHEMISTRY; NUCLEAR PROTEINS; RETINOBLASTOMA-LIKE PROTEIN P107; THYROID NEOPLASMS;

EID: 10744224642     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Aldinger KA, Samaan NA, Ibanez M and Hill CS Jr: Anaplastic carcinoma of the thyroid: a review of 84 cases of spindle and giant-cell carcinoma of the thyroid. Cancer 41: 2267-2275, 1978.
2. DeGregori J, Kowalik T and Nevins JR: Cellular targets for activation by the E2F1 transcription factor induced DNA synthesis- and G1/S-regulatory genes. Mol Cell Biol 15: 4215-4224, 1995.
3. Holm R and Nesland JM: Retinoblastoma and p53 tumor suppressor gene protein expression in carcinomas of the thyroid gland. J Pathol 172: 267-272, 1994.
4. Ito Y, Kobayashi T, Takeda T, Wakasugi E, Tamaki Y, Umeshita K, Monden T and Monden M: Expression of the retinoblastoma gene product in clinical thyroid tissues: a reason for the slow growth of thyroid carcinoma. Oncol Rep 3: 57-62, 1996.
5. Anwar F, Emond MJ, Schmidt RA, Hwang HC and Bronner MP: Retinoblastoma expression in thyroid neoplasms. Mod Pathol 13: 562-569, 2001.
6. Omura K, Nagasato A, Kanehirra E, Kinsen H, Amaya S, Kimura K, Kajita T, Nozaki Y, Mizukami Y, Nonomura A and Watanabe Y: Retinoblastoma protein and proliferating-cell nuclear antigen expression as predictors of recurrence in well-differentiated papillary thyroid carcinoma. J Clin Oncol 15: 3458-3463, 1997.
7. Grana X, Garriga J and Mayol X: Role of the retinoblastoma protein family, pRB, p107 and p130 in the negative control of cell growth. Oncogene 17: 3365-3383, 1998.
8. Ito Y, Yoshida H, Uruno T, Nakano K, Takamura Y, Miya A, Koyabayashi K, Yokozawa T, Matsuzuka F, Kuma K and Miyauchi A: p130 expression in thyroid neoplasms. Cancer Lett 192: 83-87, 2003.
9. Hedinger C, Williams ED and Sobin LH: Histological Typing of Thyroid Tumours. 2nd ed. World Health Organization. New York: Springer-Verlag, 9-11, 1988.
10. Baldi A, Esposito V, De Luca A, Howard CM, Mazazarella G, Baldi F, Caputi M and Giordano A: Differential expression of the retinoblastoma gene family members pRb/p105, p107, and pRb2/p130 in lung cancer. Clin Cancer Res 2: 1239-1245, 1996.
11. Baldi A, Esposito V, De Luca A, Fu Y, Mioli I, Giordano GG, Caputi M, Baldi F and Giordano A: Differential expression of Rb2/p130 and p107 in normal human tissues and in primary lung cancer. Clin Cancer Res 3: 16910-1697, 1997.
12. De Luca A, Baldi A, Esposito V, Howard CM, Bagella L, Rizzo P, Caputi M, Pass HI, Giordano GG, Baldi F, Carbone M and Giordano A: The retinoblastoma gene family pRb/p105, p107, pRb2/p130 and simian virus-40 large T-antigen in human mesotheliomas. Nat Med 3: 913-916, 1997.
13. Massaro-Giordano M, Baldi G, De Luca A, Baldi A and Giordano A: Differential expression of the retinoblastoma-gene family members in choroidal melanoma: prognostic significance. Clin Cancer Res 5: 1455-1458, 1999.
14. Claudio PP, Zamparelli A, Garcia FU, Claudio L, Ammirati G, Faria A, Bovicelli A, Russo G, Giordano GG, McGinnis DE, Giordano A and Cardi G: Expression of cell-cycle-regulated proteins pRb2/p130, p107, p27kip1, p53, mdm-2, ki-67 (MIB1) in prostatic gland adenocarcinoma. Clin Cancer Res 8: 1808-1815, 2002.
15. Leoncini L, Bellan C, Cossu A, Claudio PP, Lazzi S, Cinti C, Cevenini G, Megha T, Laurini L, Luzi P, Orcinoni GF, Piccioli M, Pileri S, Giardano C, Tosi P and Giordano A: Retinoblastoma-related p107 and pRb2/p130 proteins in malignant lymphomas: distinct mechanisms of cell growth control. Clin Cancer Res 5: 4065-4072, 1999.
16. Wu F, Li JQ, Miki H, Nishioka M, Fujita J, Ohmori M, Imaida K and Kuriyama S: p107 expression in colorectal tumours rises during carcinogenesis and falls during invasion. Eur J Cancer 38: 1838-1848, 2002.
17. Ito Y, Uruno R, Nakano K, Takamura Y, Miya A, Kobayashi K, Yokozawa T, Matsuzuuka F, Kuma S, Kuma K and Miyauchi A: An observation trial without surgical treatment in patients with papillary microcarcinoma of the thyroid. Thyroid, in press.
18. Ito Y, Yoshida H, Shibahara K, Uruno T, Nakano K, Takamura Y, Miya S, Kobayashi K, Yokozawa T, Matsuzuka F, Uchimi T, Kuwano M, Miyoshi E, Matsuura N, Kuma K and Miyauchi A: Y-box binding protein expression in thyroid neoplasms: its linkage with anaplastic tranformation. Pathol Int, in press.
19. Ito Y, Yoshida H, Nakano K, Kobayashi K, Yokozawa T, Hirai K, Matsuzuka F, Matsuura N, Kakudo K, Kuma K and Miyauchi A: Expression of cdc25A and cdc25B proteins in thyroid neoplasms. Br J Cancer 86: 1909-13, 2002.