The presence of high-risk HPV combined with specific p53 and p16INK4a expression patterns points to high-risk HPV as the main causative agent for adenocarcinoma in situ and adenocarcinoma of the cervix

Journal of Pathology

Volumn 201, Issue 4, 2003, Pages 535-543

  Zielinski, G Denise ^a   Snijders, Peter J F ^a   Rozendaal, Lawrence ^a   Daalmeijer, Nathalie Fransen ^a   Risse, Elle K J ^a   Voorhorst, Feja J ^a   Jiwa, N Medi ^b   van der Linden, Hans C ^c   de Schipper, Frits A ^d   Runsink, Arnold P ^e   Meijer, Chris J L M ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^b Location Alkmaar   (Netherlands)

^c JEROEN BOSCH HOSPITAL   (Netherlands)

^d Ziekenhuis Walcheren   (Netherlands)

^e District Laboratory Zeeland   (Netherlands)

Author keywords

Cervical adenocarcinoma; Cervical adenocarcinoma in situ; Endometrial adenocarcinoma; HPV; P16INK4a; p53

Indexed keywords

FORMALDEHYDE; PROTEIN P16; PROTEIN P53; VIRUS DNA;

ADULT; ARTICLE; CANCER INCIDENCE; CANCER SCREENING; CARCINOGENESIS; CONTROLLED STUDY; DISEASE MARKER; ENDOMETRIUM CARCINOMA; ENZYME IMMUNOASSAY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MASS SCREENING; MEDICAL ASSESSMENT; POLYMERASE CHAIN REACTION; PREVALENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RISK ASSESSMENT; SCORING SYSTEM; UTERINE CERVIX CARCINOMA; UTERINE CERVIX CARCINOMA IN SITU; VIRUS TYPING; WART VIRUS; WILD TYPE;

ADENOCARCINOMA; ADULT; CARCINOMA IN SITU; DNA, NEOPLASM; DNA, VIRAL; ENDOMETRIAL NEOPLASMS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, P16; GENES, P53; HUMANS; IMMUNOHISTOCHEMISTRY; MIDDLE AGED; PAPILLOMAVIRIDAE; PAPILLOMAVIRUS INFECTIONS; POLYMERASE CHAIN REACTION; RISK FACTORS; UTERINE CERVICAL NEOPLASMS;

EID: 10744223520     PISSN: 00223417     EISSN: None     Source Type: Journal    
DOI: 10.1002/path.1480     Document Type: Article

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