메뉴 건너뛰기




Volumn 184, Issue 4, 1998, Pages 360-368

p53 expression above the basal cell layer in oral mucosa is an early event of malignant transformation and has predictive value for developing oral squamous cell carcinoma

Author keywords

Carcinoma; Dysplasia; Immunohistochemistry; Leukoplakia; Maligna nt transformation; Oral mucosa; p53; Premalignant

Indexed keywords

PROTEIN P53;

EID: 0031940937     PISSN: 00223417     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9896(199804)184:4<360::AID-PATH1263>3.0.CO;2-H     Document Type: Article
Times cited : (168)

References (35)
  • 2
    • 0002169661 scopus 로고
    • Basic histopathological features of oral premalignant lesions
    • Mackenzie IC, Dabelsteen E, Squier C, eds. Iowa: University of Iowa Press
    • Kramer IRH. Basic histopathological features of oral premalignant lesions. In: Mackenzie IC, Dabelsteen E, Squier C, eds. Oral Premalignant Lesions. Iowa: University of Iowa Press, 1980; 23-24.
    • (1980) Oral Premalignant Lesions , pp. 23-24
    • Kramer, I.R.H.1
  • 3
    • 0027524636 scopus 로고
    • The incidence of p53 mutations increases with progression of head and neck cancer
    • Boyle JO, Hakim J, Koch W, et al. The incidence of p53 mutations increases with progression of head and neck cancer. Cancer Res 1993; 53: 4477-4480.
    • (1993) Cancer Res , vol.53 , pp. 4477-4480
    • Boyle, J.O.1    Hakim, J.2    Koch, W.3
  • 4
    • 0028950119 scopus 로고
    • A low incidence of p53 mutations in pre-malignant lesions of the oral cavity from non-tobacco users
    • Lazarus P, Garewell HS, Sciubba J, et al. A low incidence of p53 mutations in pre-malignant lesions of the oral cavity from non-tobacco users. Int J Cancer 1995; 60: 458-463.
    • (1995) Int J Cancer , vol.60 , pp. 458-463
    • Lazarus, P.1    Garewell, H.S.2    Sciubba, J.3
  • 5
    • 0027853193 scopus 로고
    • Expression of mutated p53 occurs in tumour-distant epithelia of head and neck cancer patients: A possible molecular basis for the development of multiple tumours
    • Nees M, Homann N, Discher H, et al. Expression of mutated p53 occurs in tumour-distant epithelia of head and neck cancer patients: a possible molecular basis for the development of multiple tumours. Cancer Res 1993; 53: 4189-4196.
    • (1993) Cancer Res , vol.53 , pp. 4189-4196
    • Nees, M.1    Homann, N.2    Discher, H.3
  • 6
    • 0026451101 scopus 로고
    • P53 mutation and protein accumulation during multistage human esophageal carcinogenesis
    • Bennett WP, Hollstein MC, Metcalf RA, et al. p53 mutation and protein accumulation during multistage human esophageal carcinogenesis. Cancer Res 1992; 52: 6092-6097.
    • (1992) Cancer Res , vol.52 , pp. 6092-6097
    • Bennett, W.P.1    Hollstein, M.C.2    Metcalf, R.A.3
  • 7
    • 0027415517 scopus 로고
    • Discordant p53 gene mutations in primary head and neck cancers and corresponding second primary cancers of the upper aerodigestive tract
    • Chung KY, Mukhopadhyay T, Kim J, et al. Discordant p53 gene mutations in primary head and neck cancers and corresponding second primary cancers of the upper aerodigestive tract. Cancer Res 1993; 53: 1676-1683.
    • (1993) Cancer Res , vol.53 , pp. 1676-1683
    • Chung, K.Y.1    Mukhopadhyay, T.2    Kim, J.3
  • 8
    • 0031022938 scopus 로고    scopus 로고
    • Field cancerisation and polyclonal p53 mutation in the upper aerodigestive tract
    • Waridel F, Estreicher A, Bron L, et al. Field cancerisation and polyclonal p53 mutation in the upper aerodigestive tract. Oncogene 1997; 14: 163-169.
    • (1997) Oncogene , vol.14 , pp. 163-169
    • Waridel, F.1    Estreicher, A.2    Bron, L.3
  • 9
    • 0028071555 scopus 로고
    • Mutations in the p53 tumor suppressor gene: Clues to cancer etiology and molecular pathogenesis
    • Greenblatt MS, Bennet WP, Hollstein M, Harris CC. Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. Cancer Res 1994; 54: 4855-4878.
    • (1994) Cancer Res , vol.54 , pp. 4855-4878
    • Greenblatt, M.S.1    Bennet, W.P.2    Hollstein, M.3    Harris, C.C.4
  • 10
    • 0028951290 scopus 로고
    • High incidence of p53 alterations (mutation, deletion, overexpression) in the head and neck primary tumours and metastases; absence of correlation with clinical outcome. Frequent protein overexpression in normal epithelium and in early non-invasive lesions
    • Ahomadegbe JC, Barrois M, Fogel S, et al. High incidence of p53 alterations (mutation, deletion, overexpression) in the head and neck primary tumours and metastases; absence of correlation with clinical outcome. Frequent protein overexpression in normal epithelium and in early non-invasive lesions. Oncogene 1995; 10: 1217-1227.
    • (1995) Oncogene , vol.10 , pp. 1217-1227
    • Ahomadegbe, J.C.1    Barrois, M.2    Fogel, S.3
  • 11
    • 0027994585 scopus 로고
    • Maintenance of identical p53 mutations throughout progression of squamous cell carcinomas of the tongue
    • Burns JE, McFarlane R, Clark LJ, et al. Maintenance of identical p53 mutations throughout progression of squamous cell carcinomas of the tongue. Oral Oncol, Eur J Cancer 1994; 30B: 335-337.
    • (1994) Oral Oncol, Eur J Cancer , vol.30 B , pp. 335-337
    • Burns, J.E.1    McFarlane, R.2    Clark, L.J.3
  • 12
    • 0028978781 scopus 로고
    • TP53 and ras mutations in metachronous tumours from patients with cancer of the upper aerodigestive tract
    • Yang H-K, Linnoila RI, Conrad NK, et al. TP53 and ras mutations in metachronous tumours from patients with cancer of the upper aerodigestive tract. Int J Cancer (Pred Oncol) 1995; 64: 229-233.
    • (1995) Int J Cancer (Pred Oncol) , vol.64 , pp. 229-233
    • Yang, H.-K.1    Linnoila, R.I.2    Conrad, N.K.3
  • 13
    • 0029597820 scopus 로고
    • Value of p53 expression in oral cancer and adjacent normal mucosa in relation to the occurrence of multiple primary carcinomas
    • Bongers V, Snow GB, Van der Waal I, Braakhuis BJM. Value of p53 expression in oral cancer and adjacent normal mucosa in relation to the occurrence of multiple primary carcinomas. Oral Oncol, Eur J Cancer 1995; 31B: 392-395.
    • (1995) Oral Oncol, Eur J Cancer , vol.31 B , pp. 392-395
    • Bongers, V.1    Snow, G.B.2    Van Der Waal, I.3    Braakhuis, B.J.M.4
  • 14
    • 0030237476 scopus 로고    scopus 로고
    • P53 - Integrating the complexity
    • Hall PA, Meek D, Lane DP. Editorial. p53 - integrating the complexity. J Pathol 1996; 180: 1-5.
    • (1996) J Pathol , vol.180 , pp. 1-5
    • Hall, P.A.1    Meek, D.2    Lane, D.P.3
  • 15
    • 0027500246 scopus 로고
    • Induction of nuclear accumulation of the tumour-suppressor protein p53 by DNA-damaging agents
    • Fritsche M, Christel H, Brandner G. Induction of nuclear accumulation of the tumour-suppressor protein p53 by DNA-damaging agents. Oncogene 1993; 8: 307-308.
    • (1993) Oncogene , vol.8 , pp. 307-308
    • Fritsche, M.1    Christel, H.2    Brandner, G.3
  • 16
    • 0028238420 scopus 로고
    • Effect of UV-irradiation on cell cycle, viability and the expression of p53, gadd153 and gadd45 genes in normal and HPV-immortalized human oral keratinocytes
    • Gujuluva CN, Baek J-H, Shin K-H, Cherrick HM, Park N-H. Effect of UV-irradiation on cell cycle, viability and the expression of p53, gadd153 and gadd45 genes in normal and HPV-immortalized human oral keratinocytes. Oncogene 1994; 9: 1819-1827.
    • (1994) Oncogene , vol.9 , pp. 1819-1827
    • Gujuluva, C.N.1    Baek, J.-H.2    Shin, K.-H.3    Cherrick, H.M.4    Park, N.-H.5
  • 18
    • 0028953478 scopus 로고
    • Implications of the p53 tumour-suppressor gene in clinical oncology
    • Chang F, Syrjanen S, Syrjanen K. Implications of the p53 tumour-suppressor gene in clinical oncology. J Clin Oncol 1995; 13: 1009-1022.
    • (1995) J Clin Oncol , vol.13 , pp. 1009-1022
    • Chang, F.1    Syrjanen, S.2    Syrjanen, K.3
  • 19
    • 0027258466 scopus 로고
    • Thymocyte apoptosis induced by p53-dependent and independent pathways
    • Clarke AR, Purdie CA, Harrison DJ, et al. Thymocyte apoptosis induced by p53-dependent and independent pathways. Nature 1993; 362: 849-852.
    • (1993) Nature , vol.362 , pp. 849-852
    • Clarke, A.R.1    Purdie, C.A.2    Harrison, D.J.3
  • 20
    • 0028124528 scopus 로고
    • P53 and human cancers
    • Lane DP. p53 and human cancers. Br Med Bull 1994; 50: 582-599.
    • (1994) Br Med Bull , vol.50 , pp. 582-599
    • Lane, D.P.1
  • 21
    • 0023030616 scopus 로고
    • Growth-dependent expression of human Mr 53,000 tumor antigen messenger RNA in normal and neoplastic cells
    • Calabretta B, Kaczmarek L, Selleri L, et al. Growth-dependent expression of human Mr 53,000 tumor antigen messenger RNA in normal and neoplastic cells. Cancer Res 1986; 46: 5738-5742.
    • (1986) Cancer Res , vol.46 , pp. 5738-5742
    • Calabretta, B.1    Kaczmarek, L.2    Selleri, L.3
  • 22
    • 0018078386 scopus 로고
    • Definition of leukoplakia and related lesions: An aid to studies on oral precancer
    • World Health Organizationi Collaborating Centre for Oral Precancerous Lesions. Definition of leukoplakia and related lesions: an aid to studies on oral precancer. Oral Surg 1978; 46: 518-539.
    • (1978) Oral Surg , vol.46 , pp. 518-539
  • 23
    • 0001802176 scopus 로고
    • Some common problems in medical research
    • Altman DG, ed. London: Chapman & Hall
    • Altman DG. Some common problems in medical research. In: Altman DG, ed. Practical Statistics for Medical Research. London: Chapman & Hall, 1995; 396-439.
    • (1995) Practical Statistics for Medical Research , pp. 396-439
    • Altman, D.G.1
  • 24
    • 0028207349 scopus 로고
    • An evaluation of six antibodies for immunohistochemistry of mutant p53 gene product in archival colorectal neoplasms
    • Baas IO, Mulder JWR, Offerhaus GJA, Vogelstein B, Hamilton SR. An evaluation of six antibodies for immunohistochemistry of mutant p53 gene product in archival colorectal neoplasms. J Pathol 1994; 172: 5-12.
    • (1994) J Pathol , vol.172 , pp. 5-12
    • Baas, I.O.1    Mulder, J.W.R.2    Offerhaus, G.J.A.3    Vogelstein, B.4    Hamilton, S.R.5
  • 25
    • 0028209387 scopus 로고
    • Variations in immunohistochemical detection of p53 protein overexpression in cervical carcinomas with different antibodies and methods of detection
    • Lambkin HA, Mothersill CM, Kelehan P. Variations in immunohistochemical detection of p53 protein overexpression in cervical carcinomas with different antibodies and methods of detection. J Pathol 1994; 172: 13-18.
    • (1994) J Pathol , vol.172 , pp. 13-18
    • Lambkin, H.A.1    Mothersill, C.M.2    Kelehan, P.3
  • 26
    • 0030087692 scopus 로고    scopus 로고
    • The use of antigen retrieval for immunohistochemical detection of p53 overexpression in malignant and benign oral mucosa: A cautionary note
    • Dowel SP, Ogden GR. The use of antigen retrieval for immunohistochemical detection of p53 overexpression in malignant and benign oral mucosa: a cautionary note. J Pral Pathol Med 1996; 25: 60-64.
    • (1996) J Pral Pathol Med , vol.25 , pp. 60-64
    • Dowel, S.P.1    Ogden, G.R.2
  • 27
    • 0027449181 scopus 로고
    • Antigen retrieval by microwave irradiation lowers immunohistological detection thresholds
    • McKee PH, Hobbs C, Hall PA. Antigen retrieval by microwave irradiation lowers immunohistological detection thresholds. Histopathology 1993; 23: 377-379.
    • (1993) Histopathology , vol.23 , pp. 377-379
    • McKee, P.H.1    Hobbs, C.2    Hall, P.A.3
  • 28
    • 0028299342 scopus 로고
    • P53 in tumour pathology: Can we trust immunohistochemistry? Revisited!
    • Hall PA, Lane DP. Editorial. p53 in tumour pathology: can we trust immunohistochemistry? Revisited! J Pathol 1994; 172: 1-4.
    • (1994) J Pathol , vol.172 , pp. 1-4
    • Hall, P.A.1    Lane, D.P.2
  • 29
    • 0028347978 scopus 로고
    • The presence of p53 protein in relation to Ki-67 as cellular proliferation marker in head and neck squamous cell carcinoma and adjacent dysplastic mucosa
    • Slootweg PJ, Koole R, Hordijk GJ. The presence of p53 protein in relation to Ki-67 as cellular proliferation marker in head and neck squamous cell carcinoma and adjacent dysplastic mucosa. Oral Oncol, Eur J Cancer 1994; 30B: 138-141.
    • (1994) Oral Oncol, Eur J Cancer , vol.30 B , pp. 138-141
    • Slootweg, P.J.1    Koole, R.2    Hordijk, G.J.3
  • 30
    • 0027528673 scopus 로고
    • High levels of p53 protein in UV irradiated normal human skin
    • Hall PA, McKee PH, Menage HP, Dover R, Lane DP. High levels of p53 protein in UV irradiated normal human skin. Oncogens 1993; 8: 203-207.
    • (1993) Oncogens , vol.8 , pp. 203-207
    • Hall, P.A.1    McKee, P.H.2    Menage, H.P.3    Dover, R.4    Lane, D.P.5
  • 32
    • 0028158007 scopus 로고
    • Activation of p53 gene expression in premalignant lesions during head and neck tumorigenesis
    • Shin DM, Kim J, Ro JY, et al. Activation of p53 gene expression in premalignant lesions during head and neck tumorigenesis. Cancer Res 1994; 54: 321-326.
    • (1994) Cancer Res , vol.54 , pp. 321-326
    • Shin, D.M.1    Kim, J.2    Ro, J.Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.