Deletion of the UT receptor gene results in the selective loss of urotensin-II contractile activity in aortae isolated from UT receptor knockout mice

British Journal of Pharmacology

Volumn 139, Issue 2, 2003, Pages 464-472

  Behm, David J ^a   Harrison, Stephen M ^b   Ao, Zhaohui ^a   Maniscalco, Kristeen ^a   Pickering, Susan J ^b,c   Grau, Evelyn V ^b,d   Woods, Tina N ^a   Coatney, Robert W ^a   Doe, Christopher P A ^a   Willette, Robert N ^a   Johns, Douglas G ^a   Douglas, Stephen A ^a  

^a GLAXOSMITHKLINE   (United States)

^b GLAXOSMITHKLINE   (United Kingdom)

^c GUY S HOSPITAL   (United Kingdom)

^d WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

Author keywords

Endothelin 1; Endothelium; GPR14; Knockout mouse; SENR; Urotensin II; UT receptor

Indexed keywords

CARBACHOL; ENDOTHELIN 1; NITROPRUSSIDE SODIUM; PHENYLEPHRINE; POTASSIUM CHLORIDE; UROTENSIN II;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL REACTIVITY; CONTROLLED STUDY; GENE DELETION; HEART EJECTION FRACTION; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART LEFT VENTRICLE ENDDIASTOLIC VOLUME; HEART OUTPUT; HEART RATE; HEART STROKE VOLUME; HEMODYNAMICS; MALE; MEAN ARTERIAL PRESSURE; MESENTERIC ARTERY; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR GENE; THORACIC AORTA; WILD TYPE;

ANIMALS; AORTA, THORACIC; BODY WEIGHT; GENE TARGETING; GENOTYPE; HEMODYNAMIC PROCESSES; HUMANS; MALE; MESENTERIC ARTERY, SUPERIOR; MICE; MICE, KNOCKOUT; MUSCLE, SMOOTH, VASCULAR; RECEPTORS, G-PROTEIN-COUPLED; UROTENSINS; VASOCONSTRICTION; VASOCONSTRICTOR AGENTS; VASODILATOR AGENTS;

EID: 10744220750     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0705254     Document Type: Article

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