Increased in vitro replication of CC chemokine receptor 5-restricted human immunodeficiency virus type 1 primary isolates in Th2 lymphocytes may correlate with AIDS progression

Scandinavian Journal of Infectious Diseases

Volumn 36, Issue 1, 2004, Pages 46-51

  Ofori, Harold ^a   Jagodziński, Paweł P ^a  

^a POZNAN UNIVERSITY OF MEDICAL SCIENCES   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CHEMOKINE RECEPTOR CCR5; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MESSENGER RNA; RANTES;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ADULT; ARTICLE; BIOSYNTHESIS; CELL SURFACE; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE COURSE; FEMALE; GENE REPLICATION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; IN VITRO STUDY; MALE; NONHUMAN; PROTEIN RESTRICTION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION; SURVIVAL; TARGET CELL; TH1 CELL; TH2 CELL; VIRUS ISOLATION; VIRUS REPLICATION;

ADULT; BASE SEQUENCE; BIOLOGICAL MARKERS; DISEASE PROGRESSION; FEMALE; HIV INFECTIONS; HIV LONG-TERM SURVIVORS; HIV-1; HUMANS; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; PROGNOSIS; RANTES; RECEPTORS, CCR5; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SAMPLING STUDIES; SEVERITY OF ILLNESS INDEX; SURVIVAL ANALYSIS; TH2 CELLS; VIRAL LOAD; VIRUS REPLICATION;

EID: 10744220513     PISSN: 00365548     EISSN: None     Source Type: Journal    
DOI: 10.1080/00365540310017087     Document Type: Article

References (16)

1. Romagnani S, del Prete G, Maretti R, Ravina A, Annunziato F, de Carli M, et al. Role of Th1/Th2 cytokines in HIV infection. Immunol Rev 1994; 140: 73-92.
2. Alkhatib G, Combadiere C, Broder CC, Feng Y, Kennedy PE, Murphy PM, Berger EA. CC CKR5: a RANTES, MIP-1alpha, MIP-1beta receptor as a fusion cofactor for macrophage-tropic HIV-1. Science 1996; 272: 1955-8.
3. Feng Y, Broder CC, Kennedy PE, Berger EA. HIV-1 entry cofactor: functional cDNA cloning of a 7-transmembrane, G protein-coupled receptor. Science 1996; 272: 872-7.
4. Bjorndal A, Deng H, Jansson M, Fiore JR, Colognesi C, Karlsson A, et al. Coreceptor usage of primary human immunodeficiency virus type 1 isolates varies according to biological phenotype. J Virol 1997; 71: 7478-87.
5. Jansson M, Backstrom E, Scarlatti G, Bjorndal A, Matsuda S, Rossi P, et al. Length variation of glycoprotein 120 V2 region in relation to biological phenotypes and coreceptor usage of primary HIV type 1 isolates. AIDS Res Hum Retroviruses 2001; 17: 1405-14.
6. Connor RI, Sheridan KE, Ceradini D, Choe S, Landau NR. Change in coreceptor use correlates with disease progression in HIV-1-infected individuals. J Exp Med 1997; 185: 621-8.
7. Kristiansen TB, Knudsen TB, Eugen-Onlsen J. Chemokine receptors and their crucial role in human immunodeficiency virus infections major breakthroughs in HIV research. Scand J Immunol 1998; 48: 339-46.
8. Moonis M, Lee B, Bailer RT, Luo Q, Montaner L J. CCR5 and CXCR4 expression correlated with X4 and R5 HIV-1 infection yet unsustained replication in Th1 and Th2 cells. AIDS 2001; 15: 1941-9.
9. Rhodes DI, Ashton L, Solomon A, Carr A, Cooper D, Kaldor J, Deacon N. Characterization of 3 nef-defective human immunodeficiency virus type 1 strains associated with long-term nonprogression. Australian Long-Term Nonprogressor Study Group. J Virol 2000; 74: 10581-8.
10. Kalinkovich A, Weisman Z, Bentwich Z. Chemokines and chemokine receptors: role in HIV infection. Immunol Lett 1999; 1: 68: 281-7.
11. Martin MP, Dean M, Smith MW, Winkler C, Gerrard B, Michael NL, et al. Genetic acceleration of AIDS progression by a promoter variant of CCR5. Science 1998; 282: 1907-11.
12. Maggi E, Mazzetti M, Ravina A, Annunziato F, de Carli M, Piccinni MP, et al. Ability of HIV to promote a Th1 to Th0 shift and to replicate preferentially in Th2 and Th0 cells. Science 1994; 265: 244-8.
13. Suzuki Y, Koyanagi Y, Tanaka Y, Murakami T, Misawa N, Maeda N, et al. Determinant in human immunodeficiency virus type 1 for efficient replication under cytokine-induced CD4(+) T-helper 1 (Th1)- and Th2-type conditions. J Virol 1999; 73: 316-24.
14. Schrum S, Probst P, Fleischer B, Zipfel PF. Synthesis of the CC-chemokines MIP-1alpha, MIP-1beta, and RANTES is associated with a type 1 immune response. J Immunol 1996 15; 157: 3598-604.
15. Galli G, Annunziato F, Mavilia C, Romagnani P, Cosmi L, Manetti R, et al. Enhanced HIV expression during Th2-oriented responses explained by the opposite regulatory effect of IL-4 and IFN-gamma of fusin/CXCR4. Eur J Immunol 1998; 28: 3280-90.
16. Hendel H, Henon N, Lebuanec H, Lachgar A, Poncelet H, Caillat-Zucman S, et al. Distinctive effects of CCR5, CCR2, and SDF1 genetic polymorphisms in AIDS progression. J Acquir Immune Defic Syndr Hum Retrovirol 1998; 19: 381-6.