Mitochondrial dysfunction in reproduction

Mitochondrion

Volumn 4, Issue 5-6 SPEC. ISS., 2004, Pages 577-600

  Jansen, Robert P S ^a   Burton, Graham J ^b  

^a UNIVERSITY OF SYDNEY   (Australia)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Embryo metabolism; In vitro fertilization; Infertility; Mitochondrial DNA; Mitochondrion; Oopause; Reproduction

Indexed keywords

MITOCHONDRIAL DNA; REACTIVE OXYGEN METABOLITE;

ARTICLE; ASPIRATION; CELL AGING; CELL COUNT; CHILD DEATH; CHILDHOOD; CONCEPTION; CYTOPLASM; DISORDERS OF MITOCHONDRIAL FUNCTIONS; EMBRYO; EMBRYO CULTURE; EMBRYO DEVELOPMENT; FEMALE STERILITY; FERTILIZATION; FERTILIZATION IN VITRO; GENE DELETION; GENE TRANSFER; GERM LINE; HUMAN; IN VITRO STUDY; INFERTILITY; LEIGH DISEASE; MENOPAUSE; MITOCHONDRIAL RESPIRATION; NATURAL SELECTION; NIDATION; NONHUMAN; OOCYTE; OOCYTE CLEAVAGE; OVARY FOLLICLE; OVULATION; OXIDATIVE PHOSPHORYLATION; PHENOTYPE; POINT MUTATION; PRIORITY JOURNAL; REJUVENATION; SPERMATOZOON MOTILITY; SURVIVAL; UTERUS;

EID: 10644284670     PISSN: 15677249     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mito.2004.07.038     Document Type: Article

References (166)

1. A.A. Alcivar L.E. Hake C.F. Millette et al. Mitochondrial gene expression in male germ cells of the mouse Dev. Biol. 135 1989 263-271
2. Ar A. Mover H. 1994. Oxygen tension in developing embryos: System inefficiency or system requirement? Israel J. Zool. 40, 307-326
3. J.A. Barritt C.A. Brenner H.E. Malter J. Cohen Mitochondria in human offspring derived from ooplasmic transplantation Hum. Reprod. 16 2001 513-516
4. M.C. Bastias S.T. McGee-Belser S.H. Bryan J.M. Vasquez In vitro deleterious effect of hypoxanthine in Ham's Nutrient Mixture F-10 culture medium on human oocyte fertilization and early embryonic development Fertil. Steril. 60 1993 876-880
5. B.D. Bavister Culture of preimplantation embryos: Facts and artifacts Hum. Reprod. Update 1 1995 91-148
6. H.M. Beere B.B. Wolf K. Cain et al. Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome Nat. Cell Biol. 2 2000 469-475
7. D.J. Benos R.S. Balaban Energy requirements of the developing mammalian blastocyst for active ion transport Biol. Reprod. 23 1980 941-947
8. Bernadi M.L. Fléchon J.-E. Delouis C. 1996. Influence of culture system and oxygen tension on the development of ovine zygotes matured and fertilized in vitro. J. Reprod. Fert. 106, 161-167
9. S.M. Bernes C. Bacino T.R. Prezant et al. Identical mitochondrial DNA deletion in mother with progressive external ophthalmoplegia and son with Pearson marrow-pancreas syndrome J. Pediatr. 123 1993 598-602
10. E. Block Quantitative morphological investigations of the follicular system in women. Variations at different ages Acta Anat 14 1952 108-123
11. C.A. Brenner Y.M. Wolny J.A. Barritt et al. Mitochondrial DNA deletion in human oocytes and embryos Mol. Hum. Reprod. 4 1998 887-892
12. M.D. Brown D.C. Wallace Molecular basis of mitochondrial disease J. Bioenerg. Biomembr. 26 1994 273-289
13. D.T. Brown D.C. Samuels E.M. Michael et al. Random genetic drift determines the level of mutant mtDNA in human primary oocytes Am. J. Hum. Genet. 68 2001 533-536
14. R. Buccione A.C. Schroeder J.J. Eppig Interactions between somatic cells and germ cells throughout mammalian oogenesis Biol. Reprod. 43 1990 543-547
15. G.J. Burton A.L. Watson J. Hempstock et al. Uterine glands provide histiotrophic nutrition for the human fetus during the first trimester of pregnancy J. Clin. Endocrinol. Metab. 87 2002 2954-2959
16. G.J. Burton J. Hempstock E. Jauniaux Oxygen, early embryonic metabolism and free radical-mediated embryopathies Reprod. Biomed. Online 6 2003 84-96
17. L. Butcher A. Coates K.L. Martin et al. Metabolism of pyruvate by the early human embryo Biol. Reprod. 58 1998 1054-1056
18. J.W. Catt M. Henman Toxic effects of oxygen on early human embryo development Hum. Reprod. 15 Suppl. 2 2000 199-206
19. L. Chao T.T. Tran T.T.n.f.i Tran The advantage of sex in the RNA virus phi6 Genetics 147 1997 953-959
20. X. Chen R. Prosser S. Simonetti et al. Rearranged mitochondrial genomes are present in human oocytes Am. J. Hum. Genet. 57 1995 239-247
21. J. Cohen R. Scott T. Schimmel et al. Birth of infant after transfer of anucleate donor oocyte cytoplasm into recipient eggs Lancet 350 1997 186-187
22. J. Cohen R. Scott M. Alikani et al. Ooplasmic transfer in mature human oocytes Mol. Hum. Reprod. 4 1998 269-280
23. G. Cortopassi N. Arnheim Accumulation of Mitochondrial DNA Mutation in Normal Aging Brain and Muscle, Mitochondrial DNA in Human Pathology 1993 Raven Press New York pp. 125-136
24. C. Danan D. Sternberg A. Van Steirteghem et al. Evaluation of parental mitochondrial inheritance in neonates born after intracytoplasmic sperm injection Am. J. Hum. Genet. 65 1999 463-473
25. C. Diez-Sanchez E. Ruiz-Pesini A.C. Lapena et al. Mitochondrial DNA content of human spermatozoa Biol. Reprod. 68 2003 180-185
26. J.T. Do J.W. Lee B.Y. Lee et al. Fate of donor mitochondrial DNA in cloned bovine embryos produced by microinjection of cumulus cells Biol. Reprod. 67 2002 555-560
27. T. Dominko M. Mitalipova B. Haley et al. Bovine oocyte cytoplasm supports development of embryos produced by nuclear transfer of somatic cell nuclei from various mammalian species Biol. Reprod. 60 1999 1496-1502
28. S.M. Downs M.P. Dow Hypoxanthine-maintained two-cell block in mouse embryos: Dependence on glucose and effect of hypoxanthine phosphoribosyltransferase inhibitors Biol. Reprod. 1991 1025-1039
29. S.M. Downs A.M. Utecht Metabolism of radiolabeled glucose by mouse oocytes and oocyte-cumulus cell complexes Biol. Reprod. 60 1999 1446-1452
30. Dumoulin J.C. Meijers C.J. Bras M. Coonen E. Geraedts J.P. Evers J.L., 1999. Effect of oxygen concentration on human in-vitro fertilization and embryo culture. Hum. Reprod. 14, 465-469
31. R.G. Edwards Conception in the Human Female 1980 Academic Press London pp. 271-415
32. S. El Mouatassim P. Guérin Y. Ménézo Expression of genes encoding antioxidant enzymes in human and mouse oocytes during the final stages of maturation Mol. Hum. Reprod. 5 1999 720-725
33. J.J. Eppig A comparison between oocyte growth in coculture with granulosa cells and oocytes with granulosa cell-oocyte junctional contact maintained in vitro J. Exp. Zool. 209 1979 345-353
34. J.J. Eppig M.J. O'Brien Development in vitro of mouse oocytes from primordial follicles Biol. Reprod. 54 1996 197-207
35. J.J. Eppig F. Chesnel Y. Hirao et al. Oocyte control of granulosa cell development: How and why Hum. Reprod. 12 Natl. Suppl. JBFS 2 1997 127-132
36. J.J. Eppig M. Hosoe M.J. O'Brien et al. Conditions that affect acquisition of developmental competence by mouse oocytes in vitro: FSH, insulin, glucose and ascorbic acid Mol. Cell. Endocrinol. 163 2000 109-116
37. M.J. Evans C. Gurer J.D. Loike et al. Mitochondrial DNA genotypes in nuclear transfer-derived cloned sheep Nat. Genet. 23 1999 90-93
38. M.J. Faddy R.G. Gosden A. Gougeon et al. Accelerated disappearance of ovarian follicles in mid-life: Implications for forecasting menopause Hum. Reprod. 7 1992 1342-1346
39. Fischer B. Bavister B.D. 1993. Oxygen tension in the oviduct and uterus of rhesus monkeys, hamsters and rabbits. J. Reprod. Fertil. 99, 673-679
40. J.T. Flood C.F. Chillik J.F.H.M. Van Uem et al. Ooplasmic transfusion: prophase germinal vesicle oocytes made developmentally competent by microinjection of metaphase II egg cytoplasm Fertil. Steril. 53 1990 1049-1054
41. S.A. Frank L.D. Hurst Mitochondria and male disease Nature 383 1996 224
42. Fujitani Y. Kasai K. Ohtani S. Nishimura K. Yamada M. Utsumi K. 1997. Effect of oxygen concentration and free radicals on in vitro development of in vitro-produced bovine embryos. J. Anim. Sci. 75, 483-489
43. Gardner D.K. Lane M. Calderon I. Leeton J. 1996. Environment of the preimplantation human embryo in vivo: Metabolite analysis of oviduct and uterine fluids and metabolism of cumulus cells. Fertil. Steril. 65, 349-353
44. D.K. Gardner Changes in requirements and utilization of nutrients during mammalian preimplantation embryo development and their significance in embryo culture Theriogenology 49 1998 83-102
45. D.A. Gook D.H. Edgar C. Stern Effect of cooling rate and dehydration regimen on the histological appearance of human ovarian cortex following cryopreservation in 1,2-propanediol Hum. Reprod. 14 1999 2061-2068
46. R.G. Gosden D.T. Baird J.C. Wade R. Webb Restoration of fertility to oophorectomized sheep by ovarian autografts stored at -196 °C Hum. Reprod. 9 1994 597-603
47. C. Graff A. Wredenberg J.P. Silva et al. Complex genetic counselling and prenatal analysis in a woman with external ophthalmoplegia and deleted mtDNA Prenat. Diagn. 20 2000 426-431
48. A.T. Grazul-Bilska L.P. Reynolds D.A. Redmer Gap junctions in the ovaries Biol. Reprod. 57 1997 947-957
49. M. Gregoire R. Morais M.A. Quilliam D. Gravel On auxotrophy for pyrimidines of respiration-deficient chick embryo cells Eur. J. Biochem. 1984 49-55
50. U. Gyllensten D. Wharton A. Josefsson A.C. Wilson Paternal inheritance of mitochondrial DNA in mice Nature 352 1991 255-257
51. A.J. Harvey K.L. Kind J.G. Thompson REDOX regulation of early embryo development Reproduction 123 2002 479-486
52. N.B. Hecht H. Liem Mitochondrial DNA is synthesized during meiosis and spermiogenesis in the mouse Exp. Cell Res. 154 1984 293-298
53. N.B. Hecht H. Liem K.C. Kleene et al. Maternal inheritance of the mouse mitochondrial genome is not mediated by a loss or gross alteration of the paternal mitochondrial DNA or by methylation of the oocyte mitochondrial DNA Dev. Biol. 102 1984 452-461
54. O. Heikinheimo W.E. Gibbons The molecular mechanisms of oocyte maturation and early embryonic development are unveiling new insights into reproductive medicine Mol. Hum. Reprod. 4 1998 745-756
55. L. Hewitson T. Dominko D. Takahashi et al. Unique checkpoints during the first cell cycle of fertilization after intracytoplasmic sperm injection in rhesus monkeys Nat. Med. 5 1999 431-433
56. R.F. Hoekstra Evolutionary origin and consequences of uniparental mitochondrial inheritance Hum. Reprod. 15 Suppl. 2 2000 102-111
57. Houghton F.D. Thompson J.G. Kennedy C.J. Leese H.J. 1996. Oxygen consumption and energy metabolism of the early mouse embryo. Mol. Reprod. Dev. 44, 476-485
58. C.C. Huang T.C. Cheng H.H. Chang et al. Birth after the injection of sperm and the cytoplasm of tripronucleate zygotes into metaphase II oocytes in patients with repeated implantation failure after assisted fertilization procedures Fertil. Steril. 72 1999 702-706
59. K. Inoue K. Nakada A. Ogura et al. Generation of mice with mitochondrial dysfunction by introducing mouse mtDNA carrying a deletion into zygotes Nat. Genet. 26 2000 176-181
60. Iwata H. Minami N. Imai H. 2000. Postnatal weight of calves derived from in vitro matured and in vitro fertilized embryos developed under various oxygen concentrations. Reprod. Fertil. Dev. 12, 391-396
61. H. Jacobs Sex, drugs and mitochondria Trends Genet. 15 1999 446
62. R.P.S. Jansen Endocrine response in the fallopian tube Endocr. Rev. 5 1984 525-551
63. R.P.S. Jansen Germline passage of mitochondria: Quantitative considerations and possible embryological sequelae Hum. Reprod. 15 Suppl. 2 2000 112-128
64. R.P.S. Jansen Origin and persistence of the mitochondrial genome Hum. Reprod. 15 Suppl. 2 2000 1-10
65. R.P.S. Jansen Female age and the chance of a baby from one in-vitro fertilisation treatment Med. J. Aust. 178 2003 258-261
66. R.P.S. Jansen V.K. Bajpai Periovulatory glycoprotein secretion in the macaque fallopian tube Am. J. Obstet. Gynecol. 147 1983 598-608
67. R.P.S. Jansen K.A. De Boer The bottleneck: Mitochondrial imperatives in oogenesis and ovarian follicular fate Mol. Cell. Endocrinol. 145 1998 81-88
68. E. Jauniaux B. Gulbis G.J. Burton Physiological implications of the materno-fetal oxygen gradient in human early pregnancy Reprod. Biomed. Online 7 2003 250-253
69. E. Jauniaux B. Gulbis G.J. Burton The human first trimester gestational sac limits rather than facilitates oxygen transfer to the foetus - a review Placenta 24 Suppl A 2003 S86-S93
70. E. Jauniaux J. Zaidi D. Jurkovic et al. Comparison of colour Doppler features and pathological findings in complicated early pregnancy Hum. Reprod. 9 1994 2432-2437
71. J.P. Jenuth A.C. Peterson K. Fu E.A. Shoubridge Random genetic drift in the female germline explains the rapid segregation of mammalian mitochondrial DNA Nat. Genet. 14 1996 146-151
72. J.P. Jenuth A.C. Peterson E.A. Shoubridge Tissue-specific selection for different mtDNA genotypes in heteroplasmic mice Nat. Genet. 16 1997 93-95
73. Johnson M.H. Nasr-Esfahani M.H. 1994. Radical solutions and cultural problems: Could free oxygen radicals be responsible for the impaired development of preimplantation mammalian embryos in vitro? BioEssays, 16, 31-38
74. Johnson M.H. Burton G.J. 1998. In Aruoma, O.I., Halliwell, B. eds., Molecular Biology of Free Radicals in Human Disease. OICA International, Saint Lucia, pp. 57-77
75. M.E. Jones Pyrimidine nucleotide biosynthesis in animals: Genes, enzymes, and regulation of UMP biosynthesis Annu. Rev. Biochem. 49 1980 253-279
76. G.M. Jones A.O. Trounson D.K. Gardner et al. Evolution of a culture protocol for successful blastocyst development and pregnancy Hum. Reprod. 13 1998 169-177
77. Jovanovic S.L. Clements D. MacLeod K. 1998. Biomarkers of oxidative stress are significantly elevated in Down syndrome. Free Radic. Biol. Med. 25, 1044-1048
78. H. Kaneda J.-I. Hayashi C. Taya et al. Elimination of paternal mitochondrial DNA in intraspecific crosses during early mouse embryogenesis Proc. Natl Acad. Sci. USA 92 1995 4542-4546
79. S. Kao H.T. Chao Y.H. Wei Mitochondrial deoxyribonucleic acid 4977-bp deletion is associated with diminished fertility and motility of human sperm Biol. Reprod. 52 1995 729-736
80. W.A. King D.L. Shepherd L. Plante et al. Nucleolar and mitochondrial morphology in bovine embryos reconstructed by nuclear transfer Mol. Reprod. Dev. 44 1996 499-506
81. D.H. Koobs Phosphate mediation of the Crabtree and Pasteur effects Science 1972 127-133
82. D.C. Krakauer A. Mira Mitochondria and germ cell death Nature 400 1999 125-126
83. D.C. Krakauer A. Mira Mitochondria and the death of oocytes Nature 403 2000 501
84. D.C. Krakauer A. Mira Reproductive biology - mitochondria and the death of oocytes - reply Nature 403 2000 501
85. M. Lane D.K. Gardner Amino acids and vitamins prevent culture-induced metabolic perturbations and associated loss of viability of mouse blastocysts Hum. Reprod. 13 1998 991-997
86. S.E. Lanzendorf J.F. Mayer J. Toner et al. Pregnancy following transfer of ooplasm from cryopreserved-thawed donor oocytes into recipient oocytes Fertil. Steril. 71 1999 575-577
87. N.G. Larsson H.G. Eiken H. Boman et al. Lack of transmission of deleted mtDNA from a woman with Kearns-Sayre syndrome to her child Am. J. Hum. Genet. 50 1992 360-363
88. T.S. Lawrence W.H. Beers N.B. Gilula Transmission of hormonal stimulation by cell-to-cell communication Nature 272 1978 501-506
89. H.J. Leese Metabolism of the preimplantation mammalian embryo Oxf. Rev. Reprod. Biol. 13 1991 35-72
90. H.J. Leese What does an embryo need? Hum. Fertil. 6 2003 180-185
91. R. Li J.P. Mather Lindane, an inhibitor of gap junction formation, abolishes oocyte directed follicle organizing activity in vitro Endocrinology 138 1997 4477-4480
92. 2. Hum. Reprod. 14, 458-464
93. M. Löffler C. Becker E. Wegerle G. Schuster Catalytic enzyme histochemistry and biochemical analysis of dihydroorotate dehydrogenase/oxidase and succinate dehydrogenase in mammalian tissues, cells and mitochondria Histochem. Cell Biol. 105 1996 119-128
94. S. Makabe P.M. Motta Migration of Human Germ Cells and their Relationship with the Developing Ovary: Ultrastructural Aspects In Developments in Ultrastructure of Reproduction 1989 Alan R. Liss New York pp. 41-54
95. D.R. Marchington V. Macaulay G.M. Hartshorne et al. Evidence from human oocytes for a genetic bottleneck in an mtDNA disease Am. J. Hum. Genet. 63 1998 769-775
96. K.L. Martin Nutritional and metabolic requirements of early cleavage stage embryos and blastocysts Hum. Fertil. (Camb.) 3 2000 247-254
97. L. Matsumoto H. Kasamatsu L. Pikó J. Vinograd Mitochondrial DNA replication in sea urchin oocytes J. Cell Biol. 63 1974 146-159
98. H. Matsumoto N. Shoji S. Sugawara et al. Microscopic analysis of enzyme activity, mitochondrial distribution and hydrogen peroxide in two-cell rat embryos J. Reprod. Fertil. 113 1998 231-238
99. M.M. Matzuk K.H. Burns M.M. Viveiros J.J. Eppig Intercellular communication in the mammalian ovary: Oocytes carry the conversation Science 296 2002 2178-2180
100. P. May-Panloup M.F. Chretien F. Savagner et al. Increased sperm mitochondrial DNA content in male infertility Hum. Reprod. 18 2003 550-556
101. J.M.L. McConnell L. Petrie Mitochondrial DNA turnover occurs during preimplantation development and can be modulated by environmental factors Reprod. Biomed. 2004 Online, in press
102. Z.A. Medvedev On the immortality of the germ line: Genetic and biochemical mechanisms. A review Mech. Ageing Develop. 17 1981 331-359
103. R.H. Mehta Growth of human preimplantation embryos in vitro Reprod. Biomed. Online 2 2001 113-119
104. A. Meinhardt B. Wilhelm J. Seitz Expression of mitochondrial marker proteins during spermatogenesis Hum. Reprod. Update 5 1999 108-119
105. F.V. Meirelles L.C. Smith Mitochondrial genotype segregation during preimplantation development in mouse heteroplasmic embryos Genetics 148 1998 877-883
106. A. Mira Why is meiosis arrested? J. Theor. Biol. 194 1998 275-287
107. Nagao Y. Totsuka Y. Atomi Y. Kaneda H. Lindahl K.F. Imai H. Yonekawa H. 1998. Decreased physical performance of congenic mice with mismatch between the nuclear and the mitochondrial genome. Genes Genet. Syst. 73, 21-27
108. H. Newton Y. Aubard A. Rutherford et al. Low temperature storage and grafting of human ovarian tissue Hum. Reprod. 11 1996 1487-1491
109. H. Niemann C. Wrenzycki Alterations of expression of developmentally important genes in preimplantation bovine embryos by in vitro culture conditions: Implications for subsequent development Theriogenology 53 2000 21-34
110. M.J. O'Brien J.K. Pendola J.J. Eppig A revised protocol for in vitro development of mouse oocytes from primordial follicles dramatically improves their developmental competence Biol. Reprod. 68 2003 1682-1686
111. K.H. Oktay M. Yih Preliminary experience with orthotopic and heterotopic transplantation of ovarian cortical strips Semin. Reprod. Med. 20 2002 63-74
112. K. Oktay D. Nugent H. Newton et al. Isolation and characterization of primordial follicles from fresh and cryopreserved human ovarian tissue Fertil. Steril. 67 1997 481-486
113. K. Oktay H. Newton Y. Aubard et al. Cryopreservation of immature human oocytes and ovarian tissue: An emerging technology? Fertil. Steril. 69 1998 1-7
114. K. Oktay K. Economos M. Kan et al. Endocrine function and oocyte retrieval after autologous transplantation of ovarian cortical strips to the forearm J. Am. Med. Assoc. 286 2001 1490-1493
115. Olson S.E. Seidel G.E. Jr. 2000. Culture of in vitro-produced bovine embryos with vitamin E improves development in vitro and after transfer to recipients. Biol. Reprod. 62, 248-252
116. Orsi N.M. Leese H.J. 2001. Protection against reactive oxygen species during mouse preimplantation embryo development: Role of EDTA, oxygen tension, catalase, superoxide dismutase and pyruvate. Mol. Reprod. Dev. 59, 44-53
117. Paszkowski T. Clarke R.N. 1996. Antioxidative capacity of preimplantation embryo culture medium declines following the incubation of poor quality embryos. Hum. Reprod. 11, 2493-2495
118. G.I. Perez A.M. Trbovi R.G. Gosden J.L. Tilly Mitochondria and the death of oocytes Nature 403 2000 500-501
119. L. Pikó L. Matsumoto Number of mitochondria and some properties of mitochondrial DNA in the mouse egg Dev. Biol. 49 1976 1-10
120. L. Pikó K.D. Taylor Amounts of mitochondrial DNA and abundance of some mitochondrial gene transcripts in early mouse embryos Dev. Biol. 123 1987 354-374
121. V.Y. Polyakov D. Fais I.I. Kireyev et al. The dynamics of structural modifications of mitochondria at the early stages of sea urchin embryonic development Cell Biol. Int. Rep. 16 1992 155-163
122. T.B. Pool Recent advances in the production of viable human embryos in vitro Reprod. Biomed. Online 4 2002 294-302
123. J. Poulton V. Macaulay D.R. Marchington Is the bottleneck cracked? Am. J. Hum. Genet. 62 1998 752-757
124. P. Reynier M.F. Chrétien F. Savagner et al. Long PCR analysis of human gamete mtDNA suggests defective mitochondrial maintenance in spermatozoa and supports the bottleneck theory for oocytes Biochem. Biophys. Res. Commun. 252 1998 373-377
125. F. Rodesch P. Simon C. Donner E. Jauniaux Oxygen measurements in endometrial and trophoblastic tissues during early pregnancy Obstet Gynecol 80 1992 283-285
126. P.L. Roubertoux F. Sluyter M. Carlier et al. Mitochondrial DNA modifies cognition in interaction with the nuclear genome and age in mice Nat. Genet. 35 2003 65-69
127. A.T. Rovio D.R. Marchington S. Donat et al. Mutations at the mitochondrial DNA polymerase (POLG) locus associated with male infertility Nat. Genet. 29 2001 261-262
128. E. Ruiz-Pesini A.C. Lapeña C. Díez-Villaseñor et al. Human mtDNA haplogroups associated with high or reduced spermatozoa motility Am. J. Hum. Genet. 67 2001 682-696
129. A. Saleh S.M. Srinivasula L. Balkir et al. Negative regulation of the Apaf-1 apoptosome by Hsp70 Nat. Cell Biol. 2 2000 476-483
130. A.H. Sathananthan A.O. Trounson C. Wood Atlas of fine structure of human sperm penetration, eggs and embryos cultured in vitro 1986 Praeger New York p. 105
131. I.E. Scheffler Mitochondria 1999 Wiley-Liss New York
132. D.B. Seifer V. DeJesus K. Hubbard Mitochondrial deletions in luteinized granulosa cells as a function of age in women undergoing in vitro fertilization Fertil. Steril. 78 2002 1046-1048
133. S. Shanske Y. Tang M. Hirano et al. Identical mitochondrial DNA deletion in a woman with ocular myopathy and in her son with pearson syndrome Am. J. Hum. Genet. 71 2002 679-683
134. M.K. Shigenaga T.M. Hagen B.N. Ames Oxidative damage and mitochondrial decay in aging Proc. Natl Acad. Sci. USA 91 1994 10771-10778
135. E.A. Shoubridge A debut for mito-mouse Nat. Genet. 26 2000 132-134
136. L.C. Smith A.A. Alcivar Cytoplasmic inheritance and its effects on development and performance J. Reprod. Fertil. Suppl. 48 1993 31-43
137. J. Spiropoulos D.M. Turnbull P.F. Chinnery Can mitochondrial DNA mutations cause sperm dysfunction? Mol. Hum. Reprod. 8 2002 719-721
138. J. St John D. Sakkas K. Dimitriadi et al. Failure of elimination of paternal mitochondrial DNA in abnormal embryos Lancet 355 2000 200
139. J.C. St John R.P. Jokhi C.L.R. Barratt Men with oligoasthenoteratozoospermia harbour higher numbers of multiple mitochondrial DNA deletions in their spermatozoa, but individual deletions are not indicative of overall aetiology Mol. Hum. Reprod. 7 2001 103-111
140. R. Steinborn M. Muller G. Brem Genetic variation in functionally important domains of the bovine mtDNA control region Biochim. Biophys. Acta 1397 1998 295-304
141. R. Steinborn V. Zakhartchenko J. Jelyazkov et al. Composition of parental mitochondrial DNA in cloned bovine embryos FEBS Lett. 426 1998 352-356
142. R. Steinborn V. Zakhartchenko E. Wolf et al. Non-balanced mix of mitochondrial DNA in cloned cattle produced by cytoplast-blastomere fusion FEBS Lett. 426 1998 357-361
143. E. Strauss Selenium's role in infertility explained [news; comment] Science 285 1999 1339
144. P. Sutovsky C.S. Navara G. Schatten Fate of the sperm mitochondria, and the incorporation, conversion, and disassembly of the sperm tail structures during bovine fertilization Biol. Reprod. 55 1996 1195-1205
145. P. Sutovsky R.D. Moreno J. Ramalho-Santos et al. Ubiquitin tag for sperm mitochondria Nature 402 2000 371-372
146. Tatemoto H. Ootaki K. Shigeta K. Muto N. 2001. Enhancement of developmental competence after in vitro fertilization of porcine oocytes by treatment with ascorbic acid 2-O-alpha-glucoside during in vitro maturation. Biol. Reprod. 65, 1800-1806
147. Thompson J.G. Partridge R.J. Houghton F.D. Cox C.I. Leese H.J. 1996. Oxygen uptake and carbohydrate metabolism by in vitro derived bovine embryos. J. Reprod. Fertil. 106, 299-306
148. W.E. Thompson J. Ramalho-Santos P. Sutovsky Ubiquitination of prohibitin in Mammalian sperm mitochondria: Possible roles in the regulation of mitochondrial inheritance and sperm quality control Biol. Reprod. 69 2003 254-260
149. D.R. Thorburn H.H.M. Dahl Mitochondrial disorders: Genetics, counseling, prenatal diagnosis and reproductive options Am. J. Med. Genet. 106 2001 102-114
150. A. Tsafriri N. Dekel S. Bar-Ami The role of maturation inhibitor in follicular regulation of oocyte maturation J. Reprod. Fertil. 64 1982 541-551
151. S. Twigg L. Wallman A. McElduff The resistant ovary syndrome in a patient with galactosemia: A clue to the natural history of ovarian failure J. Clin. Endocrinol. Metab. 81 1996 1329-1331
152. Umaoka Y. Noda Y. Narimoto K. Mori T., 1992. Effects of oxygen toxicity on early development of mouse embryos. Mol. Reprod. Develop. 31, 28-33
153. F. Ursini S. Heim M. Kiess et al. Dual function of the selenoprotein PHGPx during sperm maturation [see comments] Science 285 1999 1393-1396
154. J. Van Blerkom P. Motta The cellular basis of mammalian reproduction 1979 Urban and Schwarzenberg Munich p. 227
155. Van Blerkom J. Runner M.N. 1984. Mitochondrial reorganization during resumption of arrested meiosis in the mouse oocyte. Am. J. Anat. 171, 335-355
156. J. Van Blerkom P.W. Davis J. Lee ATP content of human oocytes and developmental potential and outcome after in-vitro fertilization and embryo transfer Hum. Reprod. 10 1995 415-424
157. J. Van Blerkom M. Antczak R. Schrader The developmental potential of the human oocyte is related to the dissolved oxygen content of follicular fluid: Association with vascular endothelial growth factor levels and perifollicular blood flow characteristics Hum. Reprod. 12 1997 1047-1055
158. J. Van Blerkom J. Sinclair P. Davis Mitochondrial transfer between oocytes: Potential applications of mitochondrial donation and the issue of heteroplasmy Hum. Reprod. 13 1998 2857-2868
159. 2+ levels in metaphase II mouse oocytes Hum. Reprod. 18 2003 2429-2440
160. A. Van Langendonckt D. Demylle C. Wyns et al. Comparison of G1.2/G2.2 and Sydney IVF cleavage/blastocyst sequential media for the culture of human embryos: A prospective, randomized, comparative study Fertil. Steril. 76 2001 1023-1031
161. A. Van Langendonckt D. Demylle C. Wyns et al. Comparison of G1.2/G2.2 and Sydney IVF cleavage/blastocyst sequential media for the culture of human embryos: A prospective, randomized, comparative study Fertil. Steril. 76 2001 1023-1031
162. A. Volz-Lingenhohl M. Solignac D. Sperlich Stable heteroplasmy for a large-scale deletion in the coding region of Drosophila subobscura mitochondrial DNA Proc. Natl Acad. Sci. USA 89 1992 11528-11532
163. T. Vorup-Jensen T. Hjort J.V. Abraham-Peskir et al. X-ray microscopy of human spermatozoa shows change of mitochondrial morphology after capacitation Hum. Reprod. 14 1999 880-884
164. D.C. Wallace Mitochondrial genetics: A paradigm for aging and degenerative diseases Science 256 1992 628-632
165. Yedwab G.A. Paz G. Homonnai T.Z. David M.P. Kraicer P.F. 1976. The temperature, pH, and partial pressure of oxygen in the cervix and uterus of women and uterus of rats during the cycle. Fertil. Steril. 27, 304-309
166. Zhang J. Wang C.-W. Krey L. Liu H. Meng L. Blaszczyk A. Adler A. Grifo J. 1998. In Kempers, R.D., Cohen, J., Haney, A.F., Younger, J.B., (eds.), Fertility and Reproductive Medicine. Elsevier Science, Amsterdam, pp. 629-635