Evidence to support a spectrum of active states for the glucagon receptor

Biochemical Society Transactions

Volumn 32, Issue 6, 2004, Pages 1037-1039

  Strudwick, N ^a   Bhogal, N ^a   Evans, N A ^b   Blaney, F E ^b   Findlay, J B C ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

cAMP regulatory element (CRE) luciterase; G protein coupled receptor (GPCR); Glucagon; Mutagenesis; Receptor activation; Ternary complex

Indexed keywords

ALANINE; ARGININE; ASPARAGINE; CYSTEINE PROTEINASE; GLUCAGON DERIVATIVE; GLUCAGON RECEPTOR; HISTIDINE; HORMONE RECEPTOR STIMULATING AGENT; NORGLUCAGON[1 HISTIDINE 9 GLUTAMIC ACID]; PARTIAL AGONIST; THREONINE; UNCLASSIFIED DRUG;

AGONIST; AMINO ACID SUBSTITUTION; CONCENTRATION (PARAMETERS); CONFERENCE PAPER; HORMONE ACTION; HUMAN; MEDIAN EFFECTIVE CONCENTRATION; MOLECULAR MODEL; MOLECULAR RECOGNITION; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN MODIFICATION; RECEPTOR ACTIVE STATE; RECEPTOR AFFINITY; RECEPTOR BINDING; RECEPTOR DENSITY; RECEPTOR INACTIVE STATE; SIGNAL TRANSDUCTION; TERNARY COMPLEX MODEL;

ANIMALS; BINDING SITES; BINDING, COMPETITIVE; GLUCAGON; HUMANS; KINETICS; RECEPTORS, GLUCAGON;

EID: 10644239043     PISSN: 03005127     EISSN: None     Source Type: Journal    
DOI: 10.1042/BST0321037     Document Type: Conference Paper

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