Complement component C1 and the collectins - First-line defense molecules in innate and acquired immunity

Trends in Immunology

Volumn 23, Issue 3, 2002, Pages 115-117

  Reid, Ken B ^a   Colomb, Maurice ^b   Petry, Franz ^c   Loos, Michael ^c  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b CEA GRENOBLE   (France)

^c JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

COLLECTIN; COMPLEMENT COMPONENT C1Q; COMPLEMENT CONTROL PROTEIN 1; COMPLEMENT CONTROL PROTEIN 2; LECTIN; MANNOSE BINDING LECTIN A; MANNOSE BINDING LECTIN C; PROTEIN; SERINE PROTEINASE; SERINE PROTEINASE 1; SERINE PROTEINASE 2; SERINE PROTEINASE 3; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; APOPTOSIS; B LYMPHOCYTE; BINDING SITE; COMPLEMENT ACTIVATION; COMPLEMENT DEFICIENCY; COMPLEMENT FIXATION; CONFERENCE PAPER; CRYSTAL STRUCTURE; DENDRITIC CELL; HUMAN; IMMUNE RESPONSE; IMMUNITY; MACROPHAGE; MOLECULE; MONOCYTE; NONHUMAN; PROTEIN DOMAIN; PROTEIN EXPRESSION; STEM CELL TRANSPLANTATION;

ANIMALS; APOPTOSIS; CALCIUM-BINDING PROTEINS; CALRETICULIN; CARRIER PROTEINS; CELL ADHESION MOLECULES; COLLECTINS; COMPLEMENT ACTIVATION; COMPLEMENT C1; COMPLEMENT C1Q; IMMUNITY, ACTIVE; IMMUNITY, NATURAL; LECTINS; MANNOSE-BINDING PROTEIN-ASSOCIATED SERINE PROTEASES; MEMBRANE GLYCOPROTEINS; RECEPTORS, COMPLEMENT; RIBONUCLEOPROTEINS; SERINE ENDOPEPTIDASES; SIGNAL TRANSDUCTION;

EID: 0036498686     PISSN: 14714906     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1471-4906(01)02164-0     Document Type: Conference Paper

References (8)

1. The crystal structure of the zymogen catalytic domain of complement protease C1r reveals that a disruptive mechanical stress is required to trigger activation of the C1 complex
2. C1qRp, a myeloid-cell receptor in blood, is predominately expressed on endothelial cells in human tissues
3. Identification of human CD93 as the phagocytic C1q receptor (C1qRp) by expression cloning
4. C1q and mannose-binding lectin engagement of cell-surface calreticulin and CD91 initiates macropinocytosis and uptake of apoptotic cells
5. -/-) mice with wild-type bone-marrow cells
6. An assay for the mannan-binding lectin pathway of complement activation
7. Lung surfactant proteins A and D protect mice against pulmonary hypersensitivity induced by Aspergillus fumigatus antigens and allergens
8. Protective role of lung sufactant D in a murine model of invasive pulmonary aspergillosis