Synthetic bryostatin analogues activate the RasGRP1 signaling pathway

Journal of Medicinal Chemistry

Volumn 47, Issue 26, 2004, Pages 6638-6644

  Stone, James C ^a   Stang, Stacey L ^a   Zheng, Yong ^a   Dower, Nancy A ^a   Brenner, Stacey E ^b   Baryza, Jeremy L ^b   Wender, Paul A ^b  

^a UNIVERSITY OF ALBERTA   (Canada)

^b STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRYOSTATIN; BRYOSTATIN 1; CD69 ANTIGEN; DIACYLGLYCEROL; GLUCOSE REGULATED PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C; RAS PROTEIN; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ARTICLE; CELL AGGREGATION; CONTROLLED STUDY; DRUG BINDING; DRUG EFFECT; DRUG POTENCY; FIBROBLAST CULTURE; FLUORESCENCE ACTIVATED CELL SORTER; GENE TRANSFER; GENE TRANSLOCATION; HUMAN; HUMAN CELL; IMMUNOMODULATION; MOUSE; NONHUMAN; ONCOGENE RAS; PROTEIN DEGRADATION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; THYMOCYTE;

ANIMALS; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; CELL AGGREGATION; CELL MEMBRANE; CELLS, CULTURED; DNA-BINDING PROTEINS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; IMMUNOLOGIC FACTORS; LACTONES; MACROLIDES; MICE; MUTATION; PHOSPHORYLATION; PROTEIN KINASE C; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; TETRADECANOYLPHORBOL ACETATE; THYMUS GLAND; TRANSFECTION;

EID: 10644219523     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0495069     Document Type: Article

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