Heteronuclear ribonucleoproteins C1 and C2, components of the spliceosome, are specific targets of interleukin 1β-converting enzyme-like proteases in apoptosis

Journal of Biological Chemistry

Volumn 271, Issue 46, 1996, Pages 29335-29341

  Waterhouse, Nigel ^a,b   Kumar, Sharad ^c   Song, Qizhong ^a   Strike, Phil ^d   Sparrow, Lindsay ^d   Dreyfuss, Gideon ^e   Alnemri, Emad S ^f   Litwack, Gerald ^f   Lavin, Martin ^a,b   Watters, Dianne ^a  

^a ROYAL BRISBANE AND WOMEN'S HOSPITAL   (Australia)

^b UNIVERSITY OF QUEENSLAND   (Australia)

^c HANSON INSTITUTE   (Australia)

^d CSIRO   (Australia)

^e UNIVERSITY OF PENNSYLVANIA   (United States)

^f THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APROTININ; BENZYLSULFONYL FLUORIDE; CERAMIDE; DNA FRAGMENT; EGTAZIC ACID; ETOPOSIDE; INTERLEUKIN 1BETA CONVERTING ENZYME; LEUPEPTIN; PEPSTATIN; PROTEINASE; RIBONUCLEOPROTEIN; TETRANDRINE; TOSYLLYSYL CHLOROMETHYL KETONE; TOSYLPHENYLALANYL CHLOROMETHYL KETONE;

AMINO ACID SEQUENCE; APOPTOSIS; ARTICLE; CELL TYPE; CONTROLLED STUDY; ENZYME SUBSTRATE; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IONIZING RADIATION; PRIORITY JOURNAL; PROTEIN ELECTROPHORESIS; PROTEIN PURIFICATION; SPLICEOSOME;

APOPTOSIS; CASPASE 1; CYSTEINE ENDOPEPTIDASES; HETEROGENEOUS-NUCLEAR RIBONUCLEOPROTEIN GROUP C; HETEROGENEOUS-NUCLEAR RIBONUCLEOPROTEINS; HUMANS; HYDROLYSIS; RADIATION TOLERANCE; RIBONUCLEOPROTEINS; SPLICEOSOMES; SUBSTRATE SPECIFICITY; TUMOR CELLS, CULTURED;

EID: 10544220838     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.46.29335     Document Type: Article

References (62)

1. Ellis, R. E., Yuan, J. Y., andHorvitz, H. R. (1991) Annu. Rev. Cell Biol. 7, 663-698
2. Steller, H. (1995) Science. 267, 1445-1449
3. Earnshaw, W. C. (1995) Curr. Opin. Cell Biol. 7, 337-343
4. Yuan, J. (1995) Curr. Opin. Cell Biol. 7, 211-214
5. Vaux, D. L., andStrasser, A. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 2239-2244
6. Nicholson, D. W. (1996) Nat. Biotechnol. 14, 297-301
7. Kerr, J. F. R., Wyllie, A. H., andCurrie, A. R. (1972) Br. J. Cancer 26, 239-257
8. Ellis, R. E., andHorwitz, H. R. (1986) Cell 44, 817-829
9. Yuan, J., Shaham, S., Ledoux, S., Ellis, H. M., andHorvitz, H. R. (1993) Cell 75, 641-652
10. Kumar, S., andHarvey, N. L. (1995) FEBS Lett. 375, 169-173
11. Kumar, S., andLavin, M. F. (1996) Cell Death Differ. 3, 255-267
12. Whyte, M. (1996) Trends Cell Biol. 6, 245-248
13. Miura, M., Abu, H., Rotello, R., Hartwieg, E. A., andYuan, J. (1993) Cell 75, 653-660
14. Kumar, S., Kinoshita, M., Noda, M., Copeland, N. G., andJenkins, N. A. (1994) Genes Dev. 8, 1613-1626
15. Faucheu, C., Diu, A., Chan, A. W. E., Blanchet, A.-M, Miossec, C., Herve, F., Collard-Dutilleul, V., Gu, Y., Aldape, R. A., Lippke, J. A., Rocher, C., Su, M. S.-S., Livingston, D. J., Hercend, T., andLalanne, J.-L. (1995) EMBO J. 14, 1914-1922
16. Fernandes-Alnemri, T., Litwack, G., andAlnemri, E. S. (1994) J. Biol. Chem. 269, 30761-30764
17. Muzio, M., Chinnaiyan, A. M., Kischkel, F. C., O'Rourke, K., Shevchenko, A., Ni, J., Scaffidi, C., Bretz, J. D., Zhang, M., Gentz, R., Mann, M., Krammer, P. H., Peter, M. E., andDixit, V. M. (1996) Cell 85, 817-827
18. Boldin, M. P., Goncharov, T. M., Goltsev, Y. V., andWallach, D. (1996) Cell 85, 803-815
19. Fernandes-Alnemri, T., Armstrong, R. C., Krebs, J., Srinivasula, S. M., Wang, L., Bullrich, F., Fritz, L. C., Trapani, J., Tomaselli, K. J., Litwack, G., andAlnemri, E. S. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 7464-7469
20. Martin, S. J., andGreen, D. R. (1995) Cell 82, 349-352
21. Lazebnik, Y. A., Kaufmann, S. H., Desnoyers, S., Poirier, G. G., andEarnshaw, W. C. (1994) Nature 371, 346-347
22. Tewari, M., Quan, L. T., O'Rourke, K., Desnoyers, S., Zeng, Z., Beidler, D. R., Poirier, G., Salvesen, G. S., andDixit, V. M. (1995) Cell 81, 801-809
23. Nicholson, D. W., Ali, A., Thornberry, N. A., Vaillancourt, J. P., Ding, C. K., Gallant, M., Gareau, Y., Griffin, P. R., Labelle, M., Lazebnik, Y. A., Munday, N. A., Raju, S. M., Smulson, M. E., Yamin, T.-T., Yu, V. L., andMiller, D. K. (1995) Nature 376, 37-43
24. Fernandes-Alnemri, T., Litwack, G., andAlnemri, E. S. (1995) Cancer Res. 55, 2737-2742
25. Casciola-Rosen, L. A., Anhalt, G. J., andRosen, A. (1995) J. Exp. Med. 182, 1625-1634
26. Song, Q., Lees-Miller, S. P., Kumar, S., Zhang, N., Chan, D. W., Smith, G. C. M., Jackson, S. P., Alnemri, A. S., Litwack, G., Khanna, K. K., andLavin, M. F. (1996) EMBO J. 15, 3238-3246
27. Gu, Y., Sarnecki, C., Aldape, R. A., Livingston, D. J., andSu, M. S.-S. (1995) J. Biol. Chem. 270, 18715-18718
28. Fernandes-Alnemri, T., Takahashi, A., Armstrong, R., Krebs, J., Fritz, L., Tomaselli, K. J., Wang, L., Yu, Z., Groce, C. M., Salvesen, G., Earnshaw, W. C., andAlnemri, E. S. (1995) Cancer Res. 55, 6045-6052
29. Lippke, J. A., Gu, Y., Sarnecki, C., Caron, P. R., andSu, M. S. (1996) J. Biol. Chem. 271, 1825-1828
30. Wang, Z. Q., Auer, B., Stingl, L., Berghammer, H., Haidacher, D., Schweiger, M., andWagner, E. F.(1995a) Genes Dev. 9, 509-520
31. Casciola-Rosen, L. A., Miller, D. K., Anhalt, G. J., andRosen, A. (1994) J. Biol. Chem. 269, 30757-30760
32. Casciola-Rosen, L., Nicholson, D. W., Chong, K. R., Rowan, K. R., Thornberry, N. A., Miller, D. K., andRosen, A. (1996) J. Exp. Med. 183, 1957-1964
33. Emoto, Y., Manome, Y., Meinhardt, G., Kisaki, H., Kharbanda, S., Robertson, M., Ghayur, T., Wong, W. W., Kamen, R., Weichselbaum, R., andKufe, D. (1995) EMBO J. 14, 6148-6156
34. Wang, X., Pai, J.-T., Wiedenfeld, E. A., Medina, J. C., Slaughter, C. A., Goldstein, J. L., andBrown, M. S. (1995) J. Biol. Chem. 270, 18044-18050
35. Wang, X., Zelenski, N. G., Yang, J., Sakai, J., Brown, M. S., andGoldstein, J. L. (1996) EMBO J. 15, 1012-1020
36. Lazebnik, Y. A., Takahashi, A., Moir, R. D., Goldman, R. D., Poirier, G. G., Kaufmann, S. H., andEarnshaw, W. C. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 9042-9048
37. Takahashi, A., Alnemri, E. S., Lazebnik, Y. A., Fernandes-Alnemri, T., Litwack, G., Moir, R. D., Goldman, R. D., Poirier, G. G., Kaufmann, S. H., andEarnshaw, W. C. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 8395-8400
38. Brancolini, C., Benedetti, M., andSchneider, C. (1995) EMBO J. 14, 5179-5190
39. Choi, Y. D., andDreyfuss, G. (1984) J. Cell Biol. 99, 1997-2004
40. Teh, B. S., Chen, P., Lavin, M. F., Seow, W. K., andThong, Y. H. (1991) Int. J. Immunopharmacol. 18, 1117-1126
41. Dreyfuss, G., Choi, Y. D., andAdam, S. A. (1984) Mol. Cell. Biol. 4, 1104-1114
42. Khanna, K. K., Wie, T., Burrows, S. R., Moss, D. J., Krajewski, S., Reed, J. C., andLavin, M. F. (1996) Cell Death Differ. 3, 291-298
43. Martin, S. J., Newmeyer, D. D., Mathias, S., Farschon, D. M., Wang, H.-G., Reed, J. C., Kolesnick, R N., andGreen, D. R. (1995) EMBO J. 14, 5191-5200
44. Compton, M. M., andCidlowski, J. A. (1987) J. Biol. Chem. 262, 8288-8292
45. Harvey, N. L., Trapani, J. A., Fernandes-Alnemri, T., Litwack G., Alnemri, E. S., andKumar, S. (1996) Genes Cells 1, 673-685
46. Thornberry, N. A., Peterson, E. P., Zhao, J. J., Howard, A. D., Griffin, P. R., andChapman, K. T. (1994) Biochemistry 33, 3934-3940
47. Swanson, M. S., Nakagawa, T. Y., LeVan, K., andDreyfuss, G. (1987) Mol. Cell. Biol. 7, 1731-1739
48. Dreyfuss, G., Matunis, M. J., Pinol-Roma, S., andBurd, C. G., (1993) Annu. Rev. Biochem. 62, 289-321
49. Kumar, S. (1995) Trends Biochem. Sci. 20, 198-202
50. Darmon, A. J., Nicholson, D. W., andBleackley, R. C. (1995) Nature 377, 446-448
51. Quan, L. T., Tewari, M., O'Rourke, K., Dixit, V., Snipas, S. J., Poirier, G., Ray, C., Pickup, D. J., andSalvesen, G. S. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 1972-1976
52. Song, Q., Burrows, S. R., Smith, G., Lees-Miller, S. P., Kumar, S., Chan, D. W., Trapani, J. A., Alnemri, E., Litwack, G., Lu, H., Moss, D. J., Jackson, S., andLavin, M. F. (1996) J. Exp. Med. 184, 619-626
53. Swanson, M. S., andDreyfuss, G. (1988) Mol. Cell. Biol. 8, 2237-2241
54. Gorlach, M., Burd, C. G., andDreyfuss, G. (1994) J. Biol. Chem. 269, 23074-23078
55. Pinol-Roma, S., andDreyfuss, G. (1992) Nature 355, 730-732
56. Moore, C. L., Chen, J., andWhoriskey, J. (1988) EMBO J. 7, 3159-3169
57. Choi, Y. D., Grabowski, P. J., Sharp, P. A., andDreyfuss, G. (1986) Science 231, 1534-1539
58. Hamilton, B. J., Nagy, E., Malter, J. S., Arrick, B. A., andRigby, W. F. C. (1993) J. Biol. Chem. 268, 8881-8887
59. Holcomb, E. R., andFriedman, D. L. (1984) J. Biol. Chem. 259, 31-40
60. Pinol-Roma, S., andDreyfuss, G. (1993) Mol. Cell. Biol. 13, 5762-5770
61. Mayrand, S. H., Dwen, P., andPederson, T. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 7764-7768
62. Tazi, J., Kornstadt, U., Rossi, F., Jeanteur, P., Cathala, G., Brunel, C., andLuhrmann, R. (1993) Nature 363, 283-286