Selective Activation of Two Sites in RNA by Acridine-Bearing Oligonucleotides for Clipping of Designated RNA Fragments

Journal of the American Chemical Society

Volumn 126, Issue 5, 2004, Pages 1430-1436

  Kuzuya, Akinori ^a   Mizoguchi, Ryo ^a   Sasayama, Takuro ^a   Zhou, Jing Min ^a   Komiyama, Makoto ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL ACTIVATION; ENZYMES; HYDROLYSIS; MASS SPECTROMETRY; RARE EARTH ELEMENTS;

IN VITRO TRANSCRIPTS; OLIGONUCLEOTIDES;

RNA;

ACRIDINE; HETERODUPLEX; LANTHANIDE; OLIGONUCLEOTIDE; RNA;

ARTICLE; CHEMICAL BOND; GENOTYPE; HETEROZYGOTE; HOMOZYGOTE; HYDROLYSIS; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; POLYACRYLAMIDE GEL ELECTROPHORESIS; RNA SEQUENCE; RNA STRUCTURE; SINGLE NUCLEOTIDE POLYMORPHISM;

ACRIDINES; APOLIPOPROTEINS E; BASE SEQUENCE; GENOTYPE; HUMANS; LUTETIUM; MOLECULAR SEQUENCE DATA; OLIGONUCLEOTIDES; POLYMORPHISM, SINGLE NUCLEOTIDE; RNA; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 1042276602     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja0389568     Document Type: Article

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43. 1G simply to facilitate the analysis. The labeling by either FAM or TMR was not employed here. The products were desalted as described in the Experimental Section and directly subjected to the MALDI-TOF MS.
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