T-cell vaccination in multiple sclerosis

Autoimmunity Reviews

Volumn 3, Issue 1, 2004, Pages 25-32

  Achiron, Anat ^a   Mandel, Mathilda ^a  

^a SHEBA MEDICAL CENTER   (Israel)

Author keywords

Autoimmunity; Experimental autoimmune encephalomyelitis; Multiple sclerosis; T cell vaccination

Indexed keywords

MULTIPLE SCLEROSIS VACCINE; MYELIN; T CELL VACCINE; UNCLASSIFIED DRUG; VACCINE;

ALLERGIC ENCEPHALITIS; AUTOIMMUNITY; CLINICAL TRIAL; DISEASE COURSE; DRUG EFFICACY; DRUG SAFETY; HUMAN; IMMUNE RESPONSE; IMMUNIZATION; MULTIPLE SCLEROSIS; NEUROIMAGING; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOGENESIS; RELAPSE; REVIEW; SIDE EFFECT; T LYMPHOCYTE; VACCINATION;

EID: 1042267434     PISSN: 15689972     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1568-9972(03)00060-0     Document Type: Review

References (30)

1. Kremenchutzky M., Cottrell D., Rice G., et al. The natural history of MS: a geographically based study. 7. Progressive-relapsing and relapsing- progressive MS: a re-evaluation. Brain. 122:(Pt 10):1999;1941-1950.
2. Wallin M.T., Page W.F., Kurtzke J.F. Epidemiology of MS in US veterans. VIII. Long-term survival after onset of MS. Brain. 123:(Pt 8):2000;1677-1687.
3. Achiron A., Barak Y. Multiple sclerosis-from probable to definite diagnosis: a 7-year prospective study. Arch Neurol. 57:(7):2000;974-979.
4. Barcellos L.F., Oksenberg J.R., Green A.J., et al. Genetic basis for clinical expression in MS. Brain. 125:(Pt 1):2002;150-158.
5. Compston A., Sawcer S. Genetic analysis of MS. Curr Neurol Neurosci Rep. 2:(3):2002;259-266.
6. Stinissen P., Raus J. Autoreactive T lymphocytes in MS: pathogenic role and therapeutic targeting. Acta Neurol Belg. 99:(1):1999;65-69.
7. Zhang J., Raus J. T cell vaccination in MS: hopes and facts. Acta Neurol Belg. 94:(2):1994;112-115.
8. Sharief M.K., Hentges R. Association between tumor necrosis factor-alpha and disease progression in patients with MS. N Engl J Med. 325:(7):1991;467-472.
9. Ben Nun A., Wekerle H., Cohen I.R. The rapid isolation of clonable antigen-specific T lymphocyte lines capable of mediating autoimmune encephalomyelitis. Eur J Immunol. 11:(3):1981;195-199.
10. Cohen I.R. T-cell vaccination for autoimmune disease: a panorama. Vaccine. 20:(5-6):2001;706-710.
11. Cohen I.R., Weiner H.L. T-cell vaccination. Immunol Today. 9:(11):1988;332-335.
12. Lider O., Reshef T., Beraud E., Ben Nun A., Cohen I.R. Anti-idiotypic network induced by T cell vaccination against EAE. Science. 239:(4836):1988;181- 183.
13. Ben Nun A., Cohen I.R. Vaccination against autoimmune encephalomyelitis (EAE): attenuated autoimmune T lymphocytes confer resistance to induction of active EAE but not to EAE mediated by the intact T lymphocyte line. Eur J Immunol. 11:(11):1981;949-952.
14. Ben Nun A., Lando Z. Detection of autoimmune cells proliferating to Myelin basic protein and selection of T cell lines that mediate EAE in mice. J Immunol. 130:(3):1983;1205-1209.
15. Cohen I.R. Vaccination against experimental autoimmune disease using autoimmune T-lymphocytes. Isr J Med Sci. 24:(12):1988;734-736.
16. Holoshitz J., Frenkel A., Ben Nun A., Cohen I.R. Autoimmune encephalomyelitis (EAE) mediated or prevented by T lymphocyte lines directed against diverse antigenic determinants of MBP. Vaccination is determinant specific. J Immunol. 131:(6):1983;2810-2813.
17. Van Der A.A., Hellings N., Medaer R., et al. T cell vaccination in MS patients with autologous CSF-derived activated T cells: results from a pilot study. Clin Exp Immunol. 131:(1):2003;155-168.
18. Kumar V., Sercarz E. Distinct levels of regulation in organ-specific autoimmune diseases. Life Sci. 65:(15):1999;1523-1530.
19. Liblau R.S., Singer S.M., McDevitt H.O. Th1 and Th2 CD4+ T cells in the pathogenesis of organ-specific autoimmune diseases. Immunol Today. 16:(1):1995;34-38.
20. Zhang J., Medaer R., Stinissen P., Hafler D., Raus J. MHC-restricted depletion of human MBP-reactive T cells by T cell vaccination. Science. 261:(5127):1993;1451-1454.
21. Zang Y.C., Hong J., Tejada S., et al. Th2 immune regulation induced by T cell vaccination in patients with MS. Eur J Immunol. 30:(3):2000;908-913.
22. Hermans G., Denzer U., Lohse A., Raus J., Stinissen P. Cellular and humoral immune responses against autoreactive T cells in MS patients after T cell vaccination. J Autoimmun. 13:(2):1999;233-246.
23. Kuniyasu Y., Takahashi T., Itoh M., Shimizu J., Toda G., Sakaguchi S. Naturally anergic and suppressive CD25(+), CD4(+) T cells as a functionally and phenotypically distinct immunoregulatory T cell subpopulation. Int Immunol. 12:(8):2000;1145-1155.
24. Takahashi T., Tagami T., Yamazaki S., et al. Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4. J Exp Med. 192:(2):2000;303-310.
25. Hafler D.A., Cohen I., Benjamin D.S., Weiner H.L. T cell vaccination in multiple sclerosis: a preliminary report. Clin Immunol Immunopathol. 62:(3):1992;307-313.
26. Medaer R., Stinissen P., Truyen L., Raus J., Zhang J. Depletion of myelin-basic-protein autoreactive T cells by T-cell vaccination: pilot trial in multiple sclerosis. Lancet. 346:(8978):1995;807-808.
27. Hermans G., Medaer R., Raus J., Stinissen P. Myelin reactive T cells after T cell vaccination in MS: cytokine profile and depletion by additional immunizations. J Neuroimmunol. 102:(1):2000;79-84.
28. Correale J., Lund B., McMillan M., Ko D.Y., McCarthy K., Weiner L.P. T cell vaccination in SP MS. J Neuroimmunol. 107:(2):2000;130-139.
29. Kurtzke J.F. Rating neurologic impairment in MS: an expanded disability status scale (EDSS). Neurology. 33:(11):1983;1444-1452.
30. Zhang J.Z., Rivera V.M., Tejada S., et al. T cell vaccination in MS: results of a preliminary study. J Neurol. 249:(2):2002;212-218.