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Volumn 102, Issue 1, 2000, Pages 79-84

Myelin reactive T cells after T cell vaccination in multiple sclerosis: Cytokine profile and depletion by additional immunizations

Author keywords

Autoimmunity; Autoreactive T cells; Cytokines; Immunotherapy; T cell vaccination

Indexed keywords

EPITOPE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 4; MYELIN BASIC PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

EID: 0033991945     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-5728(99)00157-5     Document Type: Article
Times cited : (37)

References (14)
  • 1
    • 0019487117 scopus 로고
    • Vaccination against autoimmune encephalomyelitis with T-lymphocyte line cells reactive against myelin basic protein
    • Ben-Nun A., Wekerle H., Cohen I.R. Vaccination against autoimmune encephalomyelitis with T-lymphocyte line cells reactive against myelin basic protein. Nature. 292:1981;60-61.
    • (1981) Nature , vol.292 , pp. 60-61
    • Ben-Nun, A.1    Wekerle, H.2    Cohen, I.R.3
  • 2
    • 0015264390 scopus 로고
    • Large scale preparation of myelin basic protein of several mammalian species
    • Deibler G.E., Martenson R.E., Kies M.W. Large scale preparation of myelin basic protein of several mammalian species. Prep. Biochem. 2:1972;139-144.
    • (1972) Prep. Biochem. , vol.2 , pp. 139-144
    • Deibler, G.E.1    Martenson, R.E.2    Kies, M.W.3
  • 3
    • 0031578938 scopus 로고    scopus 로고
    • Oral administration of myelin induces antigen-specific TGFβ1 secreting T cells in patients with multiple sclerosis
    • Hafler D.A., Kent S.C., Pietrusewicz M.J., Khoury S.J., Weiner H.L., Fukaura H. Oral administration of myelin induces antigen-specific TGFβ1 secreting T cells in patients with multiple sclerosis. Ann. N.Y. Acad. Sci. 835:1997;120-131.
    • (1997) Ann. N.Y. Acad. Sci. , vol.835 , pp. 120-131
    • Hafler, D.A.1    Kent, S.C.2    Pietrusewicz, M.J.3    Khoury, S.J.4    Weiner, H.L.5    Fukaura, H.6
  • 4
    • 0029743819 scopus 로고    scopus 로고
    • Cytokine phenotype of human autoreactive T cell clones specific for the immunodominant myelin basic protein peptide (83-99)
    • Hemmer B., Vergelli M., Calabresi P., Huang T., McFarland H.F., Martin R. Cytokine phenotype of human autoreactive T cell clones specific for the immunodominant myelin basic protein peptide (83-99). J. Neurosci. Res. 45:1996;852-862.
    • (1996) J. Neurosci. Res. , vol.45 , pp. 852-862
    • Hemmer, B.1    Vergelli, M.2    Calabresi, P.3    Huang, T.4    McFarland, H.F.5    Martin, R.6
  • 5
    • 0030844435 scopus 로고    scopus 로고
    • Cytokine profile of myelin basic protein-reactive T cells in multiple sclerosis and healthy individuals
    • Hermans G., Stinissen P., Hauben L., Van den Berg-Loonen E., Raus J., Zhang J. Cytokine profile of myelin basic protein-reactive T cells in multiple sclerosis and healthy individuals. Ann. Neurol. 42:1997;18-27.
    • (1997) Ann. Neurol. , vol.42 , pp. 18-27
    • Hermans, G.1    Stinissen, P.2    Hauben, L.3    Van Den Berg-Loonen, E.4    Raus, J.5    Zhang, J.6
  • 7
    • 0029167057 scopus 로고
    • Depletion of myelin-basic-protein autoreactive T cells by T cell vaccination: Pilot trial in multiple sclerosis
    • Medaer R., Stinissen P., Truyen L., Raus J., Zhang J. Depletion of myelin-basic-protein autoreactive T cells by T cell vaccination: pilot trial in multiple sclerosis. Lancet. 346:1995;807-808.
    • (1995) Lancet , vol.346 , pp. 807-808
    • Medaer, R.1    Stinissen, P.2    Truyen, L.3    Raus, J.4    Zhang, J.5
  • 8
    • 0031025835 scopus 로고    scopus 로고
    • Autoimmune pathogenesis of multiple sclerosis: Role of autoreactive T lymphocytes and new immunotherapeutic strategies
    • Stinissen P., Raus J., Zhang J. Autoimmune pathogenesis of multiple sclerosis: role of autoreactive T lymphocytes and new immunotherapeutic strategies. Crit. Rev. Immunol. 17:1997;33-75.
    • (1997) Crit. Rev. Immunol. , vol.17 , pp. 33-75
    • Stinissen, P.1    Raus, J.2    Zhang, J.3
  • 9
    • 0031680514 scopus 로고    scopus 로고
    • Myelin reactive T cells in the autoimmune pathogenesis of multiple sclerosis
    • Stinissen P., Medaer R., Raus J. Myelin reactive T cells in the autoimmune pathogenesis of multiple sclerosis. Mult. Scler. 4:1998;203-211.
    • (1998) Mult. Scler. , vol.4 , pp. 203-211
    • Stinissen, P.1    Medaer, R.2    Raus, J.3
  • 10
    • 0028951840 scopus 로고
    • Clonal expansion of myelin basic protein-reactive T cells in patients with multiple sclerosis: Restricted T cell receptor V gene rearrangements and CDR3 sequence
    • Vandevyver C., Mertens N., van den Elsen P., Medaer R., Raus J., Zhang J. Clonal expansion of myelin basic protein-reactive T cells in patients with multiple sclerosis: restricted T cell receptor V gene rearrangements and CDR3 sequence. Eur. J. Immunol. 25:1995;958-968.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 958-968
    • Vandevyver, C.1    Mertens, N.2    Van Den Elsen, P.3    Medaer, R.4    Raus, J.5    Zhang, J.6
  • 11
    • 0029796099 scopus 로고    scopus 로고
    • Suppressive vaccination with DNA encoding a variable region gene of the T-cell receptor prevents autoimmune encephalomyelitis and activates Th2 immunity
    • Waisman A., Ruiz P.J., Hirschberg D.L., Gelman A., Oksenberg J.R., Brocke S., Mor F., Cohen I.R., Steinman L. Suppressive vaccination with DNA encoding a variable region gene of the T-cell receptor prevents autoimmune encephalomyelitis and activates Th2 immunity. Nat. Med. 2:1996;899-905.
    • (1996) Nat. Med. , vol.2 , pp. 899-905
    • Waisman, A.1    Ruiz, P.J.2    Hirschberg, D.L.3    Gelman, A.4    Oksenberg, J.R.5    Brocke, S.6    Mor, F.7    Cohen, I.R.8    Steinman, L.9
  • 12
    • 0028926223 scopus 로고
    • Molecular mimicry in T cell-mediated autoimmunity: Viral peptides activate human T cell clones specific for myelin basic protein
    • Wucherpfennig K.W., Strominger J.L. Molecular mimicry in T cell-mediated autoimmunity: viral peptides activate human T cell clones specific for myelin basic protein. Cell. 80:1995;695-705.
    • (1995) Cell , vol.80 , pp. 695-705
    • Wucherpfennig, K.W.1    Strominger, J.L.2
  • 13
    • 0027448708 scopus 로고
    • MHC-restricted depletion of human myelin basic protein-reactive T cells by T cell vaccination
    • Zhang J., Medaer R., Stinissen P., Hafler D., Raus J. MHC-restricted depletion of human myelin basic protein-reactive T cells by T cell vaccination. Science. 261:1993;1451-1454.
    • (1993) Science , vol.261 , pp. 1451-1454
    • Zhang, J.1    Medaer, R.2    Stinissen, P.3    Hafler, D.4    Raus, J.5
  • 14
    • 0028875204 scopus 로고
    • In vivo clonotypic regulation of human myelin basic protein-reactive T cells by T cell vaccination
    • Zhang J., Vandevyver C., Stinissen P., Raus J. In vivo clonotypic regulation of human myelin basic protein-reactive T cells by T cell vaccination. J. Immunol. 155:1995;5868-5877.
    • (1995) J. Immunol. , vol.155 , pp. 5868-5877
    • Zhang, J.1    Vandevyver, C.2    Stinissen, P.3    Raus, J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.