Microarray-based method for detecting methylation changes of p16Ink4a gene 5′-CpG islands in gastric carcinomas

World Journal of Gastroenterology

Volumn 10, Issue 24, 2004, Pages 3553-3558

  Hou, Peng ^a   Shen, Jia Yao ^a   Ji, Mei Ju ^a   He, Nong Yue ^a   Lu, Zu Hong ^a  

^a SOUTHEAST UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BISULFITE; CYTOSINE; DNA; DNA FRAGMENT; PROTEIN P16; THYMINE; TUMOR SUPPRESSOR PROTEIN;

ARTICLE; CANCER GENETICS; CARCINOGENESIS; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; DNA MICROARRAY; DNA MODIFICATION; EPIGENETICS; GENE AMPLIFICATION; GENE LOCUS; GENE MAPPING; GENETIC ANALYSIS; GENETIC ASSOCIATION; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; HUMAN TISSUE; NUCLEOTIDE SEQUENCE; OLIGONUCLEOTIDE PROBE; POLYMERASE CHAIN REACTION; STOMACH CARCINOMA;

EID: 10244264780     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v10.i24.3553     Document Type: Article

References (23)

1. Baylin SB, Herman JG, Graff JR, Vertino PM, Issa JP. Alteration in DNA methylation: a fundamental aspect of neoplasia. Adv Cancer Res 1998; 72: 141-196
2. INK4a is an early event in lung cancer and a potential biomarker for early diagnosis. Proc Natl Acad Sci U S A 1998; 95: 11891-11896
3. INK4a promoter gene methylation in serum for detection of bladder cancer. Eur Urol 2002; 42: 622-630
4. Esteller M, Sanchez-Cespedes M, Rosell R, Sidransky D, Baylin S, Herman JG. Detection of aberrant promoter hypermethylation of tumor suppressor genes in serum DNA from non-small cell lung cancer patients. Cancer Res 1999; 59: 67-70
5. Bickle TA, Kruger DH. Biology of DNA restriction. Microbiol Rev 1993; 57: 434-450
6. Frommer M, McDonald LE, Millar DS, Collis CM, Watt F, Grigg GW, Molloy PL, Paul CL. A genomic sequenzing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands. Proc Natl Acad Sci U S A 1992; 89: 1827-1831
7. Kane MF, Loda M, Gaida GM, Lipman J, Misbra R, Goldman H, Jessup JM, Kolodner R. Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines. Cancer Res 1997; 57: 808-811
8. Herman JG, Graff JR, Myohanen S, Nelkin BD, Baylin SB. Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands. Proc Natl Acad Sci U S A 1996; 93: 9821-9826
9. Kuppuswamy MN, Hoffmann JW, Kasper CK, Spitzer SG, Groce SL, Bajaj SP. Single nucleotide primer extension to detect genetic diseases: experimental application to hemophilia B (factor IX) and cystic fibrosis genes. Proc Natl Acad Sci U S A 1991; 88: 1143-1147
10. Ink4a gene 5′-CpG islands by electrochemical method coupled with linker-PCR. Nucleic Acids Res 2003; 31: e92
11. Hiltunen MO, Alhonen L, Koistinaho J, Myohanen S, Paakkonen M, Marin S, Kosma VM, Janne J. Hypermethylation of the APC (adenomatous polyposis coli) gene promoter region in human colorectal carcinoma. Int J Cancer 1997; 70: 644-648
12. Stirzaker C, Millar DS, Paul CL, Warnecke PM, Harrison J, Vincent PC, Frommer M, Clark SJ. Extensive DNA methylation spanning the Rb promoter in retinoblastoma tumors. Cancer Res 1997; 57 2229-2237
13. Rice JC, Massey-Brown KS, Futscher BW. Aberrant methylation of the BRCA1 CpG island promoter is associated with decreased BRCA1 mRNA in sporadic breast cancer cells. Oncogene 1998; 17 1807-1812
14. Melki JR, Vincent PC, Clark SJ. Concurrent DNA hypermethylation of multiple genes in acute myeloid leukemia. Cancer Res 1999; 59: 3730-3740
15. Ahrendt SA, Halachmi S, Chow JT, Wu L, Halachmi N, Yang SC, Wehage S, Jen J, Sidransky D. Rapid p53 sequence analysis in primary lung cancer using an oligonucleotide probe array. Proc Natl Acad Sci U S A 1999; 96: 7382-7387
16. Favis R, Barany F. Mutation detection in K-ras, BRCA1, BRCA2, and p53 using PCR/LDR and universal DNA microarray. Ann N Y Acad Sci 2000; 906: 39-43
17. Wen WH, Bernstein L, Lescallett J, Beazer-Barclay Y, Sullivan-Halleyn J, White M, Press MF. Comparison of TP53 mutations identified by oligonucleotide microarray and conventional DNA sequence analysis. Cancer Res 2000; 60: 2716-2722
18. Hacia JG. Resequencing and mutational analysis using oligonucleotide microarrays. Nat Genet 1999; 21(Suppl): 42-47
19. Ink4a gene 5′-CpG islands. Clin Biochem 2003; 36: 197-202
20. Gitan RS, Shi H, Chen CM, Yan PS, Huang TH. Methylation-specific oligonucleotide microarray: a new potential for high-throughput methylation analysis. Genome Res 2002; 12: 158-164
21. Clark SJ, Harrison J, Paul CL, Frommer M. High sensitivity mapping of methylated cytosines. Nucleic Acids Res 1994; 22: 2990-2997
22. CDKN2 expression and its implications for cell immortalization and senescence. Mol Cell Biol 1996; 16: 859-867
23. Adorjan P, Distler J, Lipscher E, Model F, Muller J, Pelet C, Braun A, Florl AR, Gütig D, Grabs G, Howe A, Kursar M, Lesche R, Leu E, Lewin A, Maier S, Müller V, Otto T, Scholz C, Schulz WA, Seifert HH, Schwope I, Ziebarth H, Berlin K, Pipenbrock C, Olek A. Tumour class prediction and discovery by microarray-based DNA methylation analysis. Nucleic Acids Res 2002; 30: e21