Peptide nucleic acids (PNA)-DNA chimeras targeting transcription factors as a tool to modify gene expression

Current Drug Targets

Volumn 5, Issue 8, 2004, Pages 735-744

  Borgatti, M ^a   Finotti, A ^a   Romanelli, A ^b   Saviano, M ^b   Bianchi, N ^a   Lampronti, I ^a   Lambertini, E ^a   Penolazzi, L ^a   Nastruzzi, C ^c   Mischiati, C ^a   Piva, R ^a   Pedone, C ^b   Gambari, R ^a  

^a UNIVERSITY OF FERRARA   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^c UNIVERSITY OF PERUGIA   (Italy)

Author keywords

Decoy; Delivery; Gene therapy; Peptide nucleic acids; PNA DNA chimeras; Transcription

Indexed keywords

ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; ANTISENSE OLIGODEOXYNUCLEOTIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; PEPTIDE NUCLEIC ACID; PROTEIN P50; TRANSCRIPTION FACTOR;

APOPTOSIS; BINDING SITE; CELL CULTURE; CHIMERA; CIRCULAR DICHROISM; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME DEGRADATION; ENZYME INHIBITION; GENE EXPRESSION; GENE SEQUENCE; GENE TARGETING; GENETIC TRANSCRIPTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; IN VITRO STUDY; MOLECULAR DYNAMICS; OSTEOCLAST; PROTEIN BINDING; REVIEW;

APOPTOSIS; CELLS, CULTURED; CIRCULAR DICHROISM; DNA; GENE EXPRESSION REGULATION; GENE THERAPY; HUMANS; NF-KAPPA B; OLIGODEOXYRIBONUCLEOTIDES; PEPTIDE NUCLEIC ACIDS; TRANSCRIPTION FACTORS;

EID: 10044289325     PISSN: 13894501     EISSN: None     Source Type: Journal    
DOI: 10.2174/1389450043345155     Document Type: Review

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