Cognitive changes after acute tryptophan depletion: What can they tell us?

Psychological Medicine

Volumn 34, Issue 1, 2004, Pages 3-8

  Riedel, Wim J ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

3,4 METHYLENEDIOXYMETHAMPHETAMINE; SEROTONIN; TRYPTOPHAN;

AGING; ALZHEIMER DISEASE; AMINO ACID DEFICIENCY; BIPOLAR DEPRESSION; COGNITIVE DEFECT; DEGENERATIVE DISEASE; DISEASE MARKER; EDITORIAL; HUMAN; LEARNING DISORDER; MAJOR DEPRESSION; MEMORY DISORDER; NEUROTOXICITY; SEROTONINERGIC SYSTEM; SEROTONINERGIC TRANSMISSION;

ALZHEIMER DISEASE; COGNITION DISORDERS; DEPRESSIVE DISORDER, MAJOR; HUMAN EXPERIMENTATION; HUMANS; N-METHYL-3,4-METHYLENEDIOXYAMPHETAMINE; SEROTONIN; TRYPTOPHAN;

EID: 0942298181     PISSN: 00332917     EISSN: None     Source Type: Journal    
DOI: 10.1017/S0033291703008924     Document Type: Editorial

References (51)

1. Attenburrow, M. J., Williams, C., Odontiadis, J., Powell, J., van de Ouderaa, F., Williams. M. & Cowen, P. J. (2003). The effect of a nutritional source of tryptophan on dieting-induced changes in brain 5-HT function. Psychological Medicine 33, 1381-1386.
2. Azmitia. E. C. (2001). Modern views on an ancient chemical: serotonin effects on cell proliferation, maturation, and apoptosis. Brain Research Bulletin 56, 413-424.
3. Benkelfat. C., Ellenbogen, M. A., Dean, P., Palmour, R. M. & Young, S. N. (1994). Mood-lowering effect of tryptophan depletion. Enhanced susceptibility in young men at genetic risk for major affective disorders. Archives of General Psychiatry 51, 687-697.
4. Biggio, G., Fadda, F., Fanni, P., Tagliamonte, A. & Gessa, G. L. (1974). Rapid depletion of serum tryptophan, brain tryptophan, serotonin and 5 hydroxyindoletic acid by a tryptophan-free diet. Life Sciences 14, 1321-1329.
5. Booij, L., Van der Does, A. J. W. & Riedel, W. J. (2003). Monoamine depletion in psychiatric and healthy populations: review. Molecular Psychiatry 8, 951-973.
6. Booij, L., Van der Does, W., Benkelfat, C., Bremner, J. D., Cowen. P. J., Fava, M., Gillin, C., Leyton. M., Moore, P., Smith, K. A. & Van der Kloot, W. A. (2002). Predictors of mood response to acute tryptophan depletion. A reanalysis. Neuropsychopharmacology 27, 852-861.
7. Buhot, M. C., Martin, S. & Segu, L. (2000). Role of serotonin in memory impairment. Annals of Medicine 32, 210-221.
8. Capuron, L., Hauser, P., Hinze-Selch, D., Miller, A. H. & Neveu, P. J. (2002). Treatment of cytokine-induced depression. Brain Behavior and Immunology 16, 575-580.
9. Carpenter, L. L., Anderson, G. M., Pelton, G. H., Gudin, J. A., Kirwin, P. D., Price, L. H., Heninger, G. R. & McDougle. C. J. (1998). Tryptophan depletion during continuous CSF sampling in healthy human subjects, Neuropsychopharmacology 19, 26-35.
10. Coull, J. T., Sahakian, B. J., Middleton. H. C., Young, A. H., Park, S. B., McShane, R. H., Cowen, P. J. & Robbins, T. W. (1995 . Differential effects of clonidine, haloperidol, diazepam and tryptophan depletion on focused attention and attentional search. Psychopharmacology 121, 222-230.
11. Curran, H. V. & Verheyden, S. L. (2003). Altered response to tryptophan supplementation after long-term abstention from MDMA (ecstasy) is highly correlated with human memory function. Psychoparmacology 169, 91-103.
12. Dagher, A., Owen, A. M., Boecker. H. & Brooks, D. J. (1999). Mapping the network for planning: a correlational PET activation study with the Tower of London task. Brain 122, 1973-1987.
13. Damasio, A. R. (1994). Descartes' Error. Emotion, Reason and the Human Brain. Papermac, MacMillan Publishers: London.
14. Eccleston, D., Ashcroft, G. W. & Crawford, T. B. (1965). 5-hydroxyindole metabolism in rat brain. A study of intermediate metabolism using the technique of tryptophan loading. II. Applications and drug studies. Journal of Neurochemistry 12, 493-503.
15. Ellenbogen, M. A., Young, S. N., Dean, P., Palmour, R. M. & Benkelfat, C. (1999). Acute tryptophan depletion in healthy Young women with a family history of major affective disorder. Psychological Medicine 29, 35-46.
16. Elliott, R., Baker, S. C.. Rogers, R. D., O'Leary, D. A., Paykel, E. S., Frith. C. D., Dolan, R. J. & Sahakian, B. J. (1997). Prefrontal dysfunction in depressed patients performing a complex planning task: a study using positron emission tomography. Psychological Medicine 27. 931-942.
17. Fox, H. C., McLean. A., Turner, J. J., Parrott, A. C., Rogers, R. & Sahakian, B. J. (2002). Neuropsychological evidence of a relatively selective profile of temporal dysfunction in drug-free MDMA ('ecstasy') polydrug users. Psychopharmacology 162, 203-214.
18. Gessa, G. L., Biggio, G., Fadda. F., Corsini, G. U. & Tagliamonte, A. (1974). Effect of the oral administration of tryptophan-free amino acid mixtures on serum tryptophan, brain tryptophan and serotonin metabolism. Journal of Neurochemistry, 22, 869-870.
19. Gouzoulis-Mayfrank, E., Thim, B., Rezk, M., Hensen, G. & Daumann, J. (2003). Memory impairment suggests hippocampal dysfunction in abstinent ecstasy users. Progress in Neuropsychopharmacology and Biological Psychiatry (in the press).
20. Harrison, B. J., Olver, J. S., Norman, T. R., Burrows, G. D., Wesnes, K. A. & Nathan, P. J. (2003). Selective effects of acute serotonin and catecholamine depletion on memory in healthy women. Journal of Psychopharmacology, (in the press).
21. Klaassen, T., Riedel, W. J., Deutz, N. E. P., Van Someren, A. & Van Praag, H. M. (1999a). Specificity of the tryptophan depletion method. Psychopharmacology 141, 279-286.
22. Klaassen, T., Riedel, W. J., Honig, A., Van Someren, A., Deutz, N. E. P. & Van Praag, H. M. (1999b). Mood effects of 24-hour tryptophan depletion in healthy first degree relatives of patients with affective disorders. Biological Psychiatry 46, 489-497.
23. Klaassen, T., Riedel, W. J., Deutz, N. E. P. & Van Praag, H. M. (2002). Mood congruent memory bias induced by tryptophan depletion. Psychological Medicine 32, 167-172.
24. Kuhar, M. J., Aghajanian, G. K. & Roth, R. H. (1972). Tryptophan hydroxylase activity and synaptosomal uptake of serotonin in discrete brain regions after midbrain raphe lesions: correlations with serotonin levels and histochemical fluorescence. Brain Research 44, 165-176.
25. McAllister-Williams, R. H., Massey, A. E. & Rugg, M. D. (2002). Effects of tryptophan depletion on brain potential correlates of episodic memory retrieval. Psycopharmacology 160, 434-442.
26. McCann. U. D., Szabo. Z., Scheffel, U., Dannals, R. F. & Ricaurte, G. A. (1998). Positron emission tomographic evidence of toxic effect of MDMA ('Ecstasy') on brain serotonin neurons in human beings. Lancet 352, 1433-1437.
27. McCann, U. D., Eligulashvili, V. & Ricaurte, G. A. (2000). (+/-)3,4-Methylenedioxymethamphetamine ('Ecstasy')-induced serotonin neurotoxicity: clinical studies. Neuropsychobiology 42. 11-16.
28. Markus, C. R., Olivier, B., Panhuysen, G. E. M., van der Gugten, J., Alles, M. S., Tuiten, A., Westenberg, H. G. M., Fekkes, D., Koppeschaar, H. F. & De Haan, E. E. H. F. (2000). The bovine protein alpha-lactalbumin increases the plasma ratio of tryptophan to the other large neutral amino acids, and in vulnerable subjects raises brain serotonin activity, reduces cortisol concentration, and improves mood under stress. American Journal of Clinical Nutrition 71, 1536-1544.
29. Murphy, F. C., Sahakian, B. J., Rubinsztein, J. S., Michael. A., Rogers, R. D., Robbins, T. W. & Paykel, E. S. (1999). Emotional bias and inhibitory control processes in mania and depression. Psychological Medicine 29, 1307-1321.
30. Murphy, F. C., Smith, K. A., Cowen, P. J., Robbins, T. W. & Sahakian, B. J. (2002). The effects of tryptophan depletion on cognitive and affective processing in healthy volunteers. Psychopharmacology 163. 42-53.
31. Nishizawa, S., Benkelfat, C., Young, S. N., Leyton, M., Mzengeza. S., de Montigny, C., Blier, P. & Diksic. M. (1997). Differences between males and females in rates of serotonin synthesis in human brain. Proceedings of the National Academy, of Sciences of the USA 94, 5308-5313.
32. Owen, A. M., Downes, J. J., Sahakian, B. J., Polkey, C. E. & Robbins, T. W. (1990). Planning and spatial working memory following frontal lobe lesions in man. Neuropsychologia 28, 1021-1034.
33. Park, S. B., Coull, J. T., McShane, R. H., Young, A. H., Sahakian, B. J., Robbins, T. W. & Cowen, P. J. (1994). Tryptophan depletion in normal volunteers produces selective impairments in learning and memory. Neuropharmacology 33, 575-588.
34. Porter, R. J., Lunn, B. S., Walker, L. L., Gray, J. M., Ballard, C. G. & O'Brien, J. T. (2000). Cognitive deficit induced by acute tryptophan depletion in patients with Alzheimer's disease. American Journal of Psychiatry 157, 638-640.
35. Porter, R. J., Lunn, B. S. & O'Brien, J. T. (2003). Effects of acute tryptophan depletion on cognitive function in Alzheimer's disease and in the healthy elderly. Psychological Medicine 33, 41-49.
36. Quintin, P., Benkelfat, C.. Launay, J. M., Arnulf, I, Pointereau-Bellenger, A., Barbault. S., Alvarez, J. C., Varoquaux, O., Perez-Diaz, F., Jouvent, R. & Leboyer, M. (2001). Clinical and neurochemical effect of acute Tryptophan depletion in unaffected relatives of patients with bipolar affective disorder. Biological Psychiatry 50, 184-190.
37. Reneman, L., Booij, J., Majoie, C. B., Van Den Brink, W. & Den Heeten, G. J. (2001). Investigating the potential neurotoxicity of ecstasy (MDMA): an imaging approach. human Psychopharmacology, Clinical and Experimental 16, 579-588.
38. Ricaurte, G.A., Yuan. J. & McCann, U. D. (2000). (+/-)3.4-Methylenedioxymethamphetamine ('ecstasy')-induced serotonin neurotoxicity: studies in animals. Neuropsychobiology 42, 5-10.
39. Riedel, W. J., Klaassen. T., Deutz, N. E. P., Van Someren, A. & Van Praag. H. M. (1999). Tryptophan depletion in normal volunteers produces selective impairment in memory consolidation. Psychopharmacology 141, 362-369.
40. Riedel, W. J., Klaassen, T. & Schmitt, J. A. J. (2002). Tryptophan, mood and cognitive function. Brain, Behavior, and Immunity, 16, 581-589.
41. Rogers, R. D., Blackshaw, A. J., Middleton, H. C., Matthews, K., Hawtin, K., Crowley, C., Hopwood, A.. Wallace, C., Deakin, J. F. W., Sahakian, B. J. & Robbins, T. W. (1999). Tryptophan depletion impairs stimulus-reward learning while methylphenidate disrupts attentional control in healthy young adults: implications for the monoaminergic basis Of impulsive behaviour. Psychopharmacology 146, 482-491.
42. Rubinsztein, J., Rogers, R. D., Riedel, W. J., Mehta, M. A., Robbins, T. W. & Sahakian, B. J. (2001). Acute dietary tryptophan depletion impairs affective shifting and delayed visual recognition in healthy volunteers. Psychopharmacology 154, 319-326.
43. Rubinsztein, J. S., Michael, A., Paykel, E. S. & Sahakian, B. J. (2000). Cognitive impairment in remission in bipolar affective disorder. Psychological Medicine 30, 1025-1036.
44. Russo, S., Nielen, M. M.. Boon, J. C., Kema, I. P., Willemse, P. H., De Vries, E. G., Korf. J. & Den Boer. J. A. (2003). Neuropsychological investigation into the carcinoid syndrome. Psychopharmacology 168, 324-328.
45. Schmitt, J. A., Jorissen, B. L., Sobczak, S., van Boxtel, M. P., Hogervorst, E., Deutz, N. E. & Riedel, W. J. (2000). Tryptophan depletion impairs memory consolidation but improves focussed attention in healthy young volunteers. Journal of Psychopharmacologv 14, 21-29.
46. Sobczak, S., Riedel, W. J., Booij, L., Aan het Rot, M.. Deutz, N. E. P. & Honig, A. (2002a). Cognition following acute tryptophan depletion: differences between first-degree relatives of bipolar disorder patients and matched healthy control volunteers. Psychological Medicine 32, 503-515.
47. Sobczak, S., Honig, A., Duinen, M. v. & Riedel, W. J. (2002b). Serotonergic dysregulation in bipolar disorders; a literature review of 5-HT challenge studies. Bipolar Disorders 4. 347-356.
48. Sobczak, S., Honig, A., Nicolson, N. & Riedel, W. J. (2002c). Effects of acute tryptophan depletion on mood and cortisol release in first-degree relatives of type I and type II bipolar patients and healthy matched controls. Neuropsychopharmacology 27, 834-842.
49. Stone, T. W. (2001). Kynurenines in the CNS: from endogenous obscurity to therapeutic importance. Progress in Neurobiology 64, 185-218.
50. Young, S. N. & Gauthier, S. (1981). Tryptophan availability and the control of 5-hydroxytryptamine and tryptamine synthesis in human CNS. Advances in Experimental and Medical Biology 133, 221-230.
51. Young, S. N., Ervin, F. R., Pihl, R. O. & Finn, P. (1989). Biochemical aspects of tryptophan depletion in primates. Psychopharmacology 98. 508-511.