Increased erythrocyte adhesion in mice and humans with hereditary spherocytosis and hereditary elliptocytosis

Blood

Volumn 103, Issue 2, 2004, Pages 710-716

  Wandersee, Nancy J ^a   Olson, Scott C ^b   Holzhauer, Sandra L ^b   Hoffmann, Raymond G ^b   Barker, Jane E ^b   Hillery, Cheryl A ^b  

^a BLOOD RESEARCH INSTITUTE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

4N1K PEPTIDE; ANTIBODY; CD47 ANTIGEN; DEXTRAN SULFATE; FODRIN; LAMININ; PEPTIDE; POLYSACCHARIDE; THROMBOSPONDIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN INFARCTION; CONTROLLED STUDY; CYTOSKELETON; DISEASE MODEL; ERYTHROCYTE ADHESIVENESS; FEMALE; HEMOLYTIC ANEMIA; HEREDITARY ELLIPTOCYTOSIS; HEREDITARY SPHEROCYTOSIS; HISTOLOGY; HUMAN; HUMAN CELL; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEFICIENCY; PROTEIN IMMOBILIZATION; THROMBOSIS;

EID: 0942276836     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2003-02-0492     Document Type: Article

References (47)

1. Powars D, Wilson B, Imbus C, Pegelow C, Allen J. The natural history of stroke in sickle cell disease. Am J Med. 1978;65:461-471.
2. Armstrong FD, Thompson RJ Jr, Wang W, et al. Cognitive functioning and brain magnetic resonance imaging in children with sickle cell disease. Neuropsychology Committee of the Cooperative Study of Sickle Cell Disease. Pediatrics. 1996;97:864-870.
3. Nagel RL, Fabry ME. The panoply of animal models for sickle cell anaemia. Br J Haematol. 2001;112:19-25.
4. Paszty C, Brion CM, Manci E, et al. Transgenic knockout mice with exclusively human sickle hemoglobin and sickle cell disease. Science. 1997;278:876-878.
5. Ryan TM, Ciavatta DJ, Townes TM, Knockout-transgenic mouse model of sickle cell disease. Science. 1997;278:873-876.
6. Fabry ME, Sengupta A, Suzuka SM, et al. A second generation transgenic mouse model expressing both hemoglobin S (HbS) and HbS-Antilles results in increased phenotypic severity. Blood. 1995;86:2419-2428.
7. Trudel M, De Paepe ME, Chretien N, et al. Sickle cell disease of transgenic SAD mice. Blood. 1994;84:3189-3197.
8. Punzalan RC, Holzman SL, Trost BA, et al. Spontaneous stroke and increased erythrocyte adhesion in transgenic knockout sickle cell mice [abstract]. Blood. 1999;94:419a.
9. Franck PF, Bevers EM, Lubin BH, etal. Uncoupling of the membrane skeleton from the lipid bilayer: the cause of accelerated phospholipid flip-flop leading to an enhanced procoagulant activity of sickled cells. J Clin Invest. 1985;75:183-190.
10. Setty BN, Kulkarni S, Rao AK, Stuart MJ. Fetal hemoglobin in sickle cell disease: relationship to erythrocyte phosphatidylserine exposure and coagulation activation. Blood. 2000;96:1119-1124.
11. Setty BN, Rao AK, Stuart MJ. Thrombophilia in sickle cell disease: the red cell connection. Blood. 2001;98:3228-3233.
12. Manodori AB, Barabino GA, Lubin BH, Kuypers FA. Adherence of phosphatidylserine-exposing erythrocytes to endothelial matrix thrombospondin. Blood. 2000;95:1293-1300.
13. Setty BN, Kulkarni S, Stuart MJ. Role of erythrocyte phosphatidylserine in sickle red cell-endothelial adhesion. Blood. 2002;99:1564-1571.
14. Bodine DM, Birkenmeier CS, Barker JE. Spectrin deficient inherited hemolytic anemias in the mouse: characterization by spectrin synthesis and mRNA activity in reticulocytes. Cell. 1984;37:721-729.
15. Wandersee NJ, Roesch AN, Hamblen NR, et al. Defective spectrin integrity and neonatal thrombosis in the first mouse model for severe hereditary elliptocytosis. Blood. 2001;97:543-550.
16. Tse WT, Lux SE. Red blood cell membrane disorders. Br J Haematol. 1999;104:2-13.
17. Palek J. Hereditary elliptocytosis, spherocytosis and related disorders: consequences of a deficiency or a mutation of membrane skeletal proteins. Blood Rev. 1987;1:147-168.
18. Tokunaga Y, Ohga S, Suita S, Matsushima T, Hara T. Moyamoya syndrome with spherocytosis: effect of splenectomy on strokes. Pediatr Neurol. 2001;25:75-77.
19. Schilling RF. Spherocytosis, splenectomy, strokes, and heat attacks. Lancet. 1997:350:1677-1678.
20. Hayag-Barin JE, Smith RE, Tucker FC Jr. Hereditary spherocytosis, thrombocytosis, and chronic pulmonary emboli: a case report and review of the literature. Am J Hematol. 1998;57:82-84.
21. Nikol S, Huehns TY, Kiefmann R, Hofling B. Excessive arterial thrombus in spherocytosis: a case report. Angiology. 1997;48:743-748.
22. Wandersee NJ, Tait JF, Barker JE. Erythroid phosphatidyl serine exposure is not predictive of thrombotic risk in mice with hemolytic anemia. Blood Cells Mol Dis. 2000;26:75-83.
23. Wandersee NJ, Birkenmeier CS, Gifford EJ, Mohandas N, Barker JE. Murine hereditary spherocytosis, sph/sph, is caused by a mutation in the erythroid alpha spectrin gene. Hematol J. 2000;1:235-243.
24. Wandersee NJ, Birkenmeier CS, Bodine DM, Mohandas N, Barker JE. Mutations in the murine erythroid alpha spectrin gene alter spectrin mRNA and protein levels and spectrin incorporation into the red blood cell membrane skeleton. Blood. 2003;101:325-330.
25. Kaysser TM, Wandersee NJ, Bronson RT, Barker JE. Thrombosis and secondary hemochromatosis play major roles in the pathogenesis of jaundiced and spherocytic mice, murine models for hereditary spherocytosis. Blood. 1997;90:4610-4619.
26. Wandersee NJ, Lee JC, Deveau SA, Barker JE. Reduced incidence of thrombosis in mice with hereditary spherocytosis following neonatal treatment with normal hematopoietic cells. Blood. 2001;97:3972-3975.
27. Hillery CA, Du MC, Montgomery RR, Scott JP. Increased adhesion of erythrocytes to components of the extracellular matrix: isolation and characterization of a red blood cell lipid that binds thrombospondin and laminin. Blood. 1996;87:4879-4886.
28. Nataraian M, Udden MM, McIntire LV. Adhesion of sickle red blood cells and damage to interleukin-1 beta stimulated endothelial cells under flow in vitro. Blood. 1996;87:4845-4852.
29. Slayter HS. Secretion of thrombospondin from human blood platelets. Methods Enzymol. 1989;169:251-268.
30. Browne PV, Hebbel RP. CD36-positive stress reticulocytosis in sickle cell anemia. J Lab Clin Med. 1996;127:340-347.
31. Sugihara K, Sugihara T, Mohandas N, Hebbel RP. Thrombospondin mediates adherence of CD36+ sickle reticulocytes to enclothelial cells. Blood. 1992;80:2634-2642.
32. Swerlick RA, Eckman JR, Kumar A, Jeitler M, Wick TM. Alpha 4 beta 1-integrin expression on sickle reticulocytes: vascular cell adhesion molecule-1-dependent binding to endothelium. Blood. 1993;82:1891-1899.
33. Hillery CA, Du MC, Wang WC, Scott JP. Hydroxyurea therapy decreases the in vitro adhesion of sickle erythrocytes to thrombospondin and laminin. Br J Haematol. 2000;109:322-327.
34. Brittain JE, Mlinar KJ, Anderson CS, Orringer EP, Parise LV. Activation of sickle red blood cell adhesion via integrin-associated protein/CD47-induced signal transduction. J Clin Invest. 2001;107:1555-1562.
35. Brittain JE, Mlinar KJ, Anderson CS, Orringer EP, Parise LV. Integrin-associated protein is an adhesion receptor on sickle red blood cells for immobilized thrombospondin. Blood. 2001;97:2159-2164.
36. Hebbel RP. Beyond hemoglobin polymerization: the red blood cell membrane and sickle disease pathophysiology. Blood. 1991;77:214-237.
37. Nagel RL. A knockout of a transgenic mouse-animal models of sickle cell anemia. N Engl J Med. 1998;339:194-195.
38. Paszty C. Transgenic and gene knock-out mouse models of sickle cell anemia and the thalassemias. Curr Opin Hematol. 1997;4:88-93.
39. Beuzard Y. Transgenic mouse models of sickle cell disease. Curr Opin Hematol. 1996;3:150-155.
40. Udani M, Zen Q, Cottman M, et al. Basal cell adhesion molecule/lutheran protein: the receptor critical for sickle cell adhesion to laminin. J Clin Invest. 1998;101:2550-2558.
41. Zen Q, Cottman M, Truskey G, Fraser R, Telen MJ. Critical factors in basal cell adhesion molecule/lutheran-mediated adhesion to laminin. J Biol Chem. 1999;274:728-734.
42. Parsons SF, Lee G, Spring FA, et al. Lutheran blood group glycoprotein and its newly characterized mouse homologue specifically bind alpha5 chain-containing human laminin with high affinity. Blood. 2001;97:312-320.
43. Hillery CA, Scott JP, Du MC. The carboxy-terminal cell-binding domain of thrombospondin is essential for sickle red blood cell adhesion. Blood. 1999;94:302-309.
44. Lawler J, Duquette M, Urry L, McHenry K, Smith TF. The evolution of the thrombospondin gene family. J Mol Evol. 1993;36:509-516.
45. Lawler J, Duquette M, Ferro P, Copeland NG, Gilbert DJ, Jenkins NA. Characterization of the murine thrombospondin gene. Genomics. 1991;11:587-600.
46. Stins MF, Giles F, Kim KS. Selective expression of adhesion molecules on human brain microvascular endothelial cells. J Neuroimmunol. 1997;76:81-90.
47. Giannaki G, Rizos D, Xyni K, et al. Serum soluble E- and L-selectin in the very early neonatal period. Early Hum Dev. 2000;60:149-155.