Distribution of 3-Nitrotyrosine in the Nasal Polyps of Atopic Patients

Laryngoscope

Volumn 114, Issue 1, 2004, Pages 118-125

  Ruffoli, R ^a,b   Ursino, F ^a   Fattori, B ^a   Scavuzzo, M C ^a   Paparelli, A ^a   Gesi, M ^a   Rocchi, V ^a   Giambelluca, M A ^a   Giannessi, F ^a  

^a UNIVERSITY OF PISA   (Italy)

^b NONE   (Italy)

Author keywords

Immunohistochemistry; Nasal polyps; Nitrotyrosine

Indexed keywords

3 NITROTYROSINE; EOSIN; HEMATOXYLIN; PEROXYNITRITE;

ADULT; ARTICLE; ATOPY; CILIATED EPITHELIUM; CLINICAL ARTICLE; CONNECTIVE TISSUE; CONTROLLED STUDY; EOSINOPHIL; FEMALE; GOBLET CELL; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; MICROSCOPY; NOSE MUCOSA; NOSE POLYP; PRIORITY JOURNAL; RETROSPECTIVE STUDY; STAINING; TISSUE DISTRIBUTION; VESSEL;

ADULT; CASE-CONTROL STUDIES; EOSINOPHILS; FEMALE; HUMANS; HYPERSENSITIVITY, IMMEDIATE; IMMUNOHISTOCHEMISTRY; MALE; NASAL MUCOSA; NASAL POLYPS; PEROXYNITROUS ACID; RETROSPECTIVE STUDIES; TYROSINE;

EID: 0942276140     PISSN: 0023852X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005537-200401000-00021     Document Type: Article

References (35)

1. Hellquist HB. Nasal polyps update. Histopathology. Allergy Asthma Proc 1996;17:237-242.
2. Larsen PL, Tingsgaard PK, Harcourt J, et al. Nasal polyps and their relation to polyps/hypertrophic polypoid mucosa in the paranasal sinuses: a macro-, endo-, and microscopic study of autopsy materials. Am J Rhinol 1998;12:45-51.
3. Pawankar R. Nasal polyposis: an update. Curr Opin Allergy Clin Immunol 2003;3:1-6.
4. Kramer MF, Rasp G. Nasal polyposis: eosinophils and interleukin-5. Allergy 1999;54:669-680.
5. Mygind N, Dahl R, Bachert C. Nasal polyposis, eosinophil dominated inflammation, and allergy. Thorax 2000;55(Suppl 2):S79-s83.
6. Bernstein JM, Gorfien J, Noble B, Yankaskas JR. Nasal polyposis: immunohistochemistry and bioelectrical findings (a hypothesis for the development of nasal polyps). J Allergy Clin Immunol 1997;99:165-175.
7. Bateman ND, Fahy C, Woolford TJ. Nasal polyps: still more questions than answers. J Laryngol Otol 2003;117:1-9.
8. Park HS, Jung KS, Shute J, et al. Allergen-induced release of GM-CSF and IL-8 in vitro by nasal polyp tissue from atopic subjects prolongs eosinophil survival. Eur Respir J 1997;10:1476-1482.
9. Pang YT, Eskici O, Wilson JA. Nasal polyposis: role of subclinical delayed food hypersensitivity. Otolaryngol Head Neck Surg 2000;122:298-301.
10. Bachert C, Hormann K, Mosges R, et al. An update on the diagnosis and treatment of sinusitis and nasal polyposis. Allergy 2003;58:176-191.
11. Gaston B, Drazen JM, Loscalzo J, Stamler JS. The biology of nitrogen oxides in the airways. Am J Resp Crit Care Med 1994;149:538-551.
12. Förstermann U, Gath I, Schwarz P, et al. Isoforms of nitric-oxide synthase: properties, cellular distribution and expressional control. Biochem Pharmacol 1995;50:321-332.
13. Watkins DN, Lewis RH, Basclain KA, et al. Expression and localization of the inducible isoform of nitric oxide synthase in nasal polyp epithelium. Clin Exp Allergy 1998;28:211-219.
14. Hess A, Bloch W, Rocher J, et al. Distribution of nitric oxide-synthases under physiological and pathophysiological conditions. HNO 2000;48:489-495.
15. Kawamoto H, Takumida M, Takeno S, et al. Localization of nitric oxide synthase in human nasal mucosa with nasal allergy. Acta Otolaryngol 1998;539(Suppl):65-70.
16. Saleh D, Ernst P, Lim S, et al. Increased formation of the potent oxidant peroxynitrite in the airways of asthmatic patients is associated with induction of nitric oxide synthase: effect of inhalated glucocorticoid. FASEB J 1998;12:929-937.
17. Flak A, Goldman WE. Autotoxicity of nitric oxide in airway disease. Am J Respir Crit Care Med 1996;154:5202-5206.
18. van der Vliet A, Eiserich JP, Shigenaga MK, Cross CE. Reactive nitrogen species and tyrosine nitration in the respiratory tract. Epiphenomena or a pathobiologic mechanism of disease? Am J Respir Crit Care Med 1999;160:1-9.
19. Robbins RA, Hadeli K, Nelson D, et al. Nitric oxide, peroxynitrite, and lower respiratory tract inflammation. Immunopharmacology 2000;48:217-221.
20. Ischiropoulos H. Biological tyrosine nitration: a pathophysiological function of nitric oxide and reactive oxygen species. Arch Biochem Biophys 1998;356:1-11.
21. van der Vliet A, Cross CE. Oxidants, nitrosants, and the lung. Am J Med 2000;109:398-421.
22. Ichinose M, Sugiura H, Yamagata S, et al. Increase in reactive nitrogen species production in chronic obstructive pulmonary disease airways. Am J Respir Crit Care Med 2000;162:701-706.
23. Kaminsky DA, Mitchell J, Carrol N, et al. Nitrotyrosine formation in the airways and lung parenchyma of patients with asthma. J Allergy Clin Immunol 1999;104:747-754.
24. Sato M, Fukuyama N, Sakai M, Nakazawa H. Increased nitric oxide in nasal lavage fluid and nitrotyrosine formation in nasal mucosa indices for severe perennial nasal allergy. Clin Exp Allergy 1998;8:597-605.
25. Kang BH, Chen SS, Jou LS, et al. Immunolocalization of inducible nitric oxide synthase and 3-nitrotyrosine in the nasal mucosa of patients with rhinitis. Eur Arch Otorhinolaryngol 2000;257:242-246.
26. Malorny U, Bildau H, Sorg C. Efficient inhibition of endogenous peroxidase without antigen denaturation in immunohistochemistry. J Immunol Methods 1988;111:101-107.
27. Hebestreit H, Dibbert B, Balatti I, et al. Disruption of Fas receptor signaling by nitric oxide in eosinophils. J Exp Med 1998;187:415-425.
28. Wu W, Chen Y, Hazen SL. Eosinophil peroxidase nitrates protein tyrosyl residues. J Biol Chem 1999;274:25933-25944.
29. Sadeghi-Hashjin G, Folkerts G, Henricks PA, et al. Peroxynitrite induces airway hyperresponsiveness in guinea pigs in vitro and in vivo. Am J Respir Crit Care Med 1996;153:1697-1701.
30. Duguet A, Iijima H, Eum SY, et al. Eosinophil peroxidase mediates protein nitration in allergic airway inflammation in mice. Am J Respir Crit Care Med 2001;164:1119-1126.
31. MacPherson JC, Comhair SA, Erzurum SC, et al. Eosinophils are a major source of nitric-oxide derived oxidants in severe asthma: characterization of pathways available to eosinophils for generating reactive nitrogen species. J Immunol 2001;166:5763-5772.
32. Brennan ML, Wu W, Fu X, et al. A tale of two controversies: defining both the role of peroxidases in nitrotyrosine formation in vivo using eosinophil peroxidase and myeloperoxidase-deficient mice, and the nature of peroxidase-generated reactive nitrogen species. J Biol Chem 2002; 277:17415-17427.
33. Sato E, Simpson KL, Grisham MB, et al. Effects of reactive oxygen and nitrogen metabolites on eotaxin induced eosinophil chemotactic activity in vitro. Am J Respir Cell Mol Biol 2000;22:61-67.
34. Sato E, Simpson KL, Grisham MB, et al. Effects of reactive oxygen and nitrogen metabolites on RANTES- and IL-5-induced eosinophil chemotactic activity in vitro. Am J Pathol 1999;155:591-598.
35. Cross CE, Halliwell B, Allen A. Antioxidant protection: a function of tracheobronchial and gastrointestinal mucus. Lancet 1994;1:1328-1330.