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Volumn 33, Issue 2, 2004, Pages 137-152

Drug interactions in the hematopoietic stem cell transplant (HSCT) recipient: What every transplanter needs to know

Author keywords

Azoles; Cyclosporine; CYP3A4; Cytochrome P450; Drug interactions; Pharmacokinetic; Tacrolimus

Indexed keywords

AMLODIPINE; ASTEMIZOLE; ATORVASTATIN; BENZODIAZEPINE DERIVATIVE; CALCINEURIN INHIBITOR; CARBAMAZEPINE; CASPOFUNGIN; CHLORAMPHENICOL; CYCLOSPORIN; CYTOCHROME P450; CYTOCHROME P450 1A2; CYTOCHROME P450 2C19; CYTOCHROME P450 2C9; CYTOCHROME P450 2D6; CYTOCHROME P450 3A4; DILTIAZEM; FLUCONAZOLE; GLYCOPROTEIN P; ITRACONAZOLE; MIDAZOLAM; OMEPRAZOLE; RAPAMYCIN; RIFABUTIN; RIFAMPICIN; SIMVASTATIN; TACROLIMUS; TERFENADINE; TRIAZOLAM; UNINDEXED DRUG; VORICONAZOLE;

EID: 0842345617     PISSN: 02683369     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bmt.1704316     Document Type: Short Survey
Times cited : (47)

References (145)
  • 1
    • 0034004083 scopus 로고    scopus 로고
    • Effects of the antifungal agents on oxidative drug metabolism clinical relevance
    • Venkatakrishnan K, von Moltke LL, Greenblatt DJ. Effects of the antifungal agents on oxidative drug metabolism clinical relevance. Clin Pharmacokinet 2000; 38: 111-180.
    • (2000) Clin. Pharmacokinet. , vol.38 , pp. 111-180
    • Venkatakrishnan, K.1    von Moltke, L.L.2    Greenblatt, D.J.3
  • 2
    • 0004341978 scopus 로고    scopus 로고
    • Cytochrome P450 drug interaction table
    • (online) Available from URL: (accessed October 22)
    • Flockhart DA. Cytochrome P450 drug interaction table (online). Available from URL: http://medicine.iupui.edu/flockhart/ (accessed October 22, 2002).
    • (2002)
    • Flockhart, D.A.1
  • 3
    • 0025688972 scopus 로고
    • Role of cytochromes P450 in drug metabolism and hepatotoxicity
    • Watkins PB. Role of cytochromes P450 in drug metabolism and hepatotoxicity. Semin Liver Dis 1990; 10: 235-250.
    • (1990) Semin. Liver Dis. , vol.10 , pp. 235-250
    • Watkins, P.B.1
  • 4
    • 0035187828 scopus 로고    scopus 로고
    • Pharmacokinetic aspects of treating infections in the intensive care unit: Focus on drug interactions
    • Pea F, Farlanut M. Pharmacokinetic aspects of treating infections in the intensive care unit: focus on drug interactions. Clin Pharmacokinet 2001; 40: 833-868.
    • (2001) Clin. Pharmacokinet. , vol.40 , pp. 833-868
    • Pea, F.1    Farlanut, M.2
  • 5
    • 0032240434 scopus 로고    scopus 로고
    • Relationship of tacrolimus (FK506) whole blood concentrations and efficacy and safety after HLA-identical sibling bone marrow transplantation
    • Wingard JR, Nash RA, Przepiorka D et al. Relationship of tacrolimus (FK506) whole blood concentrations and efficacy and safety after HLA-identical sibling bone marrow transplantation. Biol Blood Marrow Transplant 1998; 4: 157-163.
    • (1998) Biol. Blood Marrow Transplant. , vol.4 , pp. 157-163
    • Wingard, J.R.1    Nash, R.A.2    Przepiorka, D.3
  • 6
    • 0032618092 scopus 로고    scopus 로고
    • Relationship of tacrolimus whole blood levels to efficacy and safety outcomes after unrelated donor marrow transplantation
    • Przepiorka D, Nash RA, Wingard JR et al. Relationship of tacrolimus whole blood levels to efficacy and safety outcomes after unrelated donor marrow transplantation. Biol Blood Marrow Transplant 1999; 5: 94-97.
    • (1999) Biol. Blood Marrow Transplant. , vol.5 , pp. 94-97
    • Przepiorka, D.1    Nash, R.A.2    Wingard, J.R.3
  • 7
    • 0029560982 scopus 로고
    • Metabolism of the immunosuppressant tacrolimus in the small intestine: Cytochrome P450, drug interactions, and interindividual variability
    • Lampen A, Christians V, Guengerich FP et al. Metabolism of the immunosuppressant tacrolimus in the small intestine: cytochrome P450, drug interactions, and interindividual variability. Drug Metab Dispos 1995; 23: 1315-1324.
    • (1995) Drug Metab. Dispos. , vol.23 , pp. 1315-1324
    • Lampen, A.1    Christians, V.2    Guengerich, F.P.3
  • 8
    • 0036380025 scopus 로고    scopus 로고
    • Mechanisms of clinically relevant drug interactions associated with tacrolimus
    • Christians U, Jacobsen W, Benet LZ et al. Mechanisms of clinically relevant drug interactions associated with tacrolimus. Clin Pharmacokinet 2002; 41: 813-851.
    • (2002) Clin. Pharmacokinet. , vol.41 , pp. 813-851
    • Christians, U.1    Jacobsen, W.2    Benet, L.Z.3
  • 9
    • 0029913912 scopus 로고    scopus 로고
    • Evaluation of the drug interaction between high dose fluconazole and cyclosporine or tacrolimus in bone marrow transplant patients
    • Osowski CL, Dix SP, Lin L et al. Evaluation of the drug interaction between high dose fluconazole and cyclosporine or tacrolimus in bone marrow transplant patients. Transplantation 1996; 61: 1268-1272.
    • (1996) Transplantation , vol.61 , pp. 1268-1272
    • Osowski, C.L.1    Dix, S.P.2    Lin, L.3
  • 10
    • 0028341698 scopus 로고
    • Fluconazole therapy in transplant recipients receiving FK506
    • Manez R, Martin M, Raman D et al. Fluconazole therapy in transplant recipients receiving FK506. Transplantation 1994; 57: 1521-1523.
    • (1994) Transplantation , vol.57 , pp. 1521-1523
    • Manez, R.1    Martin, M.2    Raman, D.3
  • 11
    • 0141971948 scopus 로고    scopus 로고
    • Characterizing the pharmacokinetic (PK) drug interaction between intravenous (IV) itraconazole (ITRA) and IV tacrolimus (FK506) or IV cyclosporine (CyA) in allogeneic bone marrow transplant (alloBMT) patients
    • Chicago, IL, 16-19 December 2001 (abstract A-33). Washington, DC: American Society of Microbiology
    • Leather HL, Wingard JR. Characterizing the pharmacokinetic (PK) drug interaction between intravenous (IV) itraconazole (ITRA) and IV tacrolimus (FK506) or IV cyclosporine (CyA) in allogeneic bone marrow transplant (alloBMT) patients. In: Program and Abstracts of the 41st Interscience Conference on Antimicrobial Agents and Chemotherapy, Chicago, IL, 16-19 December 2001 (abstract A-33). Washington, DC: American Society of Microbiology, 2001.
    • (2001) Program and Abstracts of the 41st Interscience Conference on Antimicrobial Agents and Chemotherapy
    • Leather, H.L.1    Wingard, J.R.2
  • 12
    • 0035077872 scopus 로고    scopus 로고
    • Coadministration of itraconazole and tacrolimus after thoracic organ transplantation
    • Banerjee R, Leaver N, Lyster H et al. Coadministration of itraconazole and tacrolimus after thoracic organ transplantation. Transplant Proc 2001; 33: 1600-1602.
    • (2001) Transplant. Proc. , vol.33 , pp. 1600-1602
    • Banerjee, R.1    Leaver, N.2    Lyster, H.3
  • 13
    • 0031671850 scopus 로고    scopus 로고
    • Evidence for a pharmacokinetic interaction between itraconazole and tacrolimus in organ transplant patients
    • Billaud EM, Guillemain R, Tacco F et al. Evidence for a pharmacokinetic interaction between itraconazole and tacrolimus in organ transplant patients. Br J Clin Pharmacol 1998; 46: 271-272.
    • (1998) Br. J. Clin. Pharmacol. , vol.46 , pp. 271-272
    • Billaud, E.M.1    Guillemain, R.2    Tacco, F.3
  • 14
    • 0032880418 scopus 로고    scopus 로고
    • Effects of itraconazole on tacrolimus blood concentrations in a renal transplant recipient
    • Capone D, Gentile A, Imperatore P et al. Effects of itraconazole on tacrolimus blood concentrations in a renal transplant recipient. Ann Pharmacother 1999; 33: 1124-1125.
    • (1999) Ann. Pharmacother. , vol.33 , pp. 1124-1125
    • Capone, D.1    Gentile, A.2    Imperatore, P.3
  • 15
    • 0031935987 scopus 로고    scopus 로고
    • Interaction between tacrolimus and itraconazole in a heart-lung transplant recipient
    • Furlan V, Parquin F, Penaud JF et al. Interaction between tacrolimus and itraconazole in a heart-lung transplant recipient. Transplant Proc 1998; 30: 187-188.
    • (1998) Transplant. Proc. , vol.30 , pp. 187-188
    • Furlan, V.1    Parquin, F.2    Penaud, J.F.3
  • 16
    • 85044703484 scopus 로고    scopus 로고
    • Tacrolimus-itraconazole interaction in a kidney transplant patient
    • Outeda Macias M, Salvador P, Hurtado JL et al. Tacrolimus-itraconazole interaction in a kidney transplant patient. Ann Pharmacother 2000; 34: 536.
    • (2000) Ann. Pharmacother. , vol.34 , pp. 536
    • Outeda Macias, M.1    Salvador, P.2    Hurtado, J.L.3
  • 18
    • 0036290197 scopus 로고    scopus 로고
    • Pharmacokinetic interaction between tacrolimus and diltiazem: Dose-response relationship in kidney and liver transplant recipients
    • Jones TE, Morris RG. Pharmacokinetic interaction between tacrolimus and diltiazem: dose-response relationship in kidney and liver transplant recipients. Clin Pharmacokinet 2002; 41: 381-388.
    • (2002) Clin. Pharmacokinet. , vol.41 , pp. 381-388
    • Jones, T.E.1    Morris, R.G.2
  • 19
    • 0033032643 scopus 로고    scopus 로고
    • Diltiazem increases tacrolimus concentrations
    • Hebert MF, Lam AY. Diltiazem increases tacrolimus concentrations. Ann Pharmacother 1999; 33: 680-682.
    • (1999) Ann. Pharmacother. , vol.33 , pp. 680-682
    • Hebert, M.F.1    Lam, A.Y.2
  • 20
    • 0032571985 scopus 로고    scopus 로고
    • Interaction between tacrolimus and chloramphenicol in a renal transplant recipient
    • Schulman SL, Shaw LM, Jabs K et al. Interaction between tacrolimus and chloramphenicol in a renal transplant recipient. Transplantation 1998; 65: 1397-1398.
    • (1998) Transplantation , vol.65 , pp. 1397-1398
    • Schulman, S.L.1    Shaw, L.M.2    Jabs, K.3
  • 21
    • 24844431814 scopus 로고    scopus 로고
    • Safety, tolerability and drug interactions of adjuvant imatinib mesylate (Gleevec) within the first 100 days following stem cell transplantation (SCT) in patients with Ph + CML and Ph + ALL at high risk for recurrence
    • (abstract 2500)
    • Sheth SR, Hicks K, Ippoliti C et al. Safety, tolerability and drug interactions of adjuvant imatinib mesylate (Gleevec) within the first 100 days following stem cell transplantation (SCT) in patients with Ph + CML and Ph + ALL at high risk for recurrence. Blood 2002; 100: 635a (abstract 2500).
    • (2002) Blood , vol.100
    • Sheth, S.R.1    Hicks, K.2    Ippoliti, C.3
  • 22
    • 0345062248 scopus 로고    scopus 로고
    • Acute tacrolimus nephrotoxicity in renal transplant patients treated with clarithromycin
    • Gomez G, Alvarez ML, Errasti P et al. Acute tacrolimus nephrotoxicity in renal transplant patients treated with clarithromycin. Transplant Proc 1999; 31: 2250-2251.
    • (1999) Transplant. Proc. , vol.31 , pp. 2250-2251
    • Gomez, G.1    Alvarez, M.L.2    Errasti, P.3
  • 23
    • 0028113105 scopus 로고
    • Interaction between FK506 and clarithromycin in a renal transplant patient
    • Wolter K, Wagner K, Philipp T et al. Interaction between FK506 and clarithromycin in a renal transplant patient. Eur J Clin Pharmacol 1994; 47: 207-208.
    • (1994) Eur. J. Clin. Pharmacol. , vol.47 , pp. 207-208
    • Wolter, K.1    Wagner, K.2    Philipp, T.3
  • 24
    • 84919577304 scopus 로고
    • Interaction between tacrolimus and erythromycin
    • Jensen C, Jordan M, Shapiro R et al. Interaction between tacrolimus and erythromycin. Lancet 1994; 344: 825.
    • (1994) Lancet , vol.344 , pp. 825
    • Jensen, C.1    Jordan, M.2    Shapiro, R.3
  • 26
    • 0031418822 scopus 로고    scopus 로고
    • Interaction between tacrolimus and erythromycin
    • Padhi ID, Long P, Basha M et al. Interaction between tacrolimus and erythromycin. Ther Drug Monitor 1997; 19: 120-122.
    • (1997) Ther. Drug Monitor. , vol.19 , pp. 120-122
    • Padhi, I.D.1    Long, P.2    Basha, M.3
  • 27
    • 0034061281 scopus 로고    scopus 로고
    • Use of phenobarbital in the management of acute tacrolimus toxicity: A case report
    • McLaughlin GE, Rossique-Gonzalez M, Gelman B et al. Use of phenobarbital in the management of acute tacrolimus toxicity: a case report. Transplant Proc 2000; 32: 665-668.
    • (2000) Transplant. Proc. , vol.32 , pp. 665-668
    • McLaughlin, G.E.1    Rossique-Gonzalez, M.2    Gelman, B.3
  • 29
    • 0032895989 scopus 로고    scopus 로고
    • Effects of rifampin on tacrolimus pharmacokinetics in healthy volunteers
    • Hebert MF, Fisher RM, March CL et al. Effects of rifampin on tacrolimus pharmacokinetics in healthy volunteers. J Clin Pharmacol 1999; 39: 91-96.
    • (1999) J. Clin. Pharmacol. , vol.39 , pp. 91-96
    • Hebert, M.F.1    Fisher, R.M.2    March, C.L.3
  • 30
    • 0033984346 scopus 로고    scopus 로고
    • Renal allograft dysfunction associated with rifampin-tacrolimus interaction
    • Chenhsu RY, Loong CC, Chou MH et al. Renal allograft dysfunction associated with rifampin-tacrolimus interaction. Ann Pharmacother 2000; 34: 27-31.
    • (2000) Ann. Pharmacother. , vol.34 , pp. 27-31
    • Chenhsu, R.Y.1    Loong, C.C.2    Chou, M.H.3
  • 31
    • 0029012986 scopus 로고
    • Interaction between FK506 and rifampicin or erythromycin in pediatric liver recipients
    • Furlan V, Perello L, Jacquemin E et al. Interaction between FK506 and rifampicin or erythromycin in pediatric liver recipients. Transplantation 1995; 59: 1217-1218.
    • (1995) Transplantation , vol.59 , pp. 1217-1218
    • Furlan, V.1    Perello, L.2    Jacquemin, E.3
  • 32
    • 0037181419 scopus 로고    scopus 로고
    • Tacrolimus-induced nephrotoxicity unmasked by induction of the CYP3A4 system with St John's wort
    • Bolley R, Zulke C, Kammerl M et al. Tacrolimus-induced nephrotoxicity unmasked by induction of the CYP3A4 system with St John's wort. Transplantation 2002; 73: 1009-1010.
    • (2002) Transplantation , vol.73 , pp. 1009-1010
    • Bolley, R.1    Zulke, C.2    Kammerl, M.3
  • 33
    • 0034048447 scopus 로고    scopus 로고
    • Interaction between theophylline and tacrolimus in a renal transplant patient
    • Boubenider S, Vincent I, Lambotte O et al. Interaction between theophylline and tacrolimus in a renal transplant patient. Nephrol Dial Transplant 2000; 15: 1066-1068.
    • (2000) Nephrol. Dial. Transplant. , vol.15 , pp. 1066-1068
    • Boubenider, S.1    Vincent, I.2    Lambotte, O.3
  • 34
    • 0024356502 scopus 로고
    • Interaction of fluconazole with cyclosporin
    • Collignon P, Hurley B, Mitchell D. Interaction of fluconazole with cyclosporin. Lancet 1989; 1: 1262.
    • (1989) Lancet , vol.1 , pp. 1262
    • Collignon, P.1    Hurley, B.2    Mitchell, D.3
  • 35
    • 0026530722 scopus 로고
    • Drug interactions with fluconazole
    • Tett S, Carey D, Lee HS. Drug interactions with fluconazole. Med J Austr 1992; 156: 365.
    • (1992) Med. J. Austr. , vol.156 , pp. 365
    • Tett, S.1    Carey, D.2    Lee, H.S.3
  • 38
    • 0024357290 scopus 로고
    • Interaction of fluconazole with cyclosporin
    • Ehninger G, Jaschonek K, Schuler U et al. Interaction of fluconazole with cyclosporin. Lancet 1989; 2: 104-405.
    • (1989) Lancet , vol.2 , pp. 104-405
    • Ehninger, G.1    Jaschonek, K.2    Schuler, U.3
  • 39
    • 0025058297 scopus 로고
    • Cyclosporin toxicity at therapeutic blood levels and cytochrome P-450 IIIA
    • Lucey MR, Kolars JC, Merion RM et al. Cyclosporin toxicity at therapeutic blood levels and cytochrome P-450 IIIA. Lancet 1990; 335: 11-15.
    • (1990) Lancet , vol.335 , pp. 11-15
    • Lucey, M.R.1    Kolars, J.C.2    Merion, R.M.3
  • 40
    • 0027284797 scopus 로고
    • Fluconazole-cyclosporine interaction: A dose-dependent effect?
    • Lopez-Gill JA. Fluconazole-cyclosporine interaction: a dose-dependent effect? Ann Pharmacother 1993; 27: 427-430.
    • (1993) Ann. Pharmacother. , vol.27 , pp. 427-430
    • Lopez-Gill, J.A.1
  • 41
    • 0025893763 scopus 로고
    • Interaction between cyclosporin and fluconazole in renal allograft recipients
    • Canafax DM, Graves NM, Hilligoss DM et al. Interaction between cyclosporin and fluconazole in renal allograft recipients. Transplantation 1991; 51: 1014-1018.
    • (1991) Transplantation , vol.51 , pp. 1014-1018
    • Canafax, D.M.1    Graves, N.M.2    Hilligoss, D.M.3
  • 42
    • 0024367870 scopus 로고
    • Absence of significant interaction of fluconazole with cyclosporin
    • Kruger HU, Schuler U, Zimmermann R et al. Absence of significant interaction of fluconazole with cyclosporin. J Antimicrob Chemother 1989; 24: 781-786.
    • (1989) J. Antimicrob. Chemother. , vol.24 , pp. 781-786
    • Kruger, H.U.1    Schuler, U.2    Zimmermann, R.3
  • 43
    • 0024995451 scopus 로고
    • Cyclosporine and itraconazole interaction in heart and lung transplant recipients
    • Kramer MR, Marshall SE, Denning DW et al. Cyclosporine and itraconazole interaction in heart and lung transplant recipients. Ann Intern Med 1990; 113: 327-329.
    • (1990) Ann. Intern. Med. , vol.113 , pp. 327-329
    • Kramer, M.R.1    Marshall, S.E.2    Denning, D.W.3
  • 44
    • 0023243662 scopus 로고
    • Interaction of cyclosporin and itraconazole
    • Kwan JT, Foxall PJ, Davidson DG et al. Interaction of cyclosporin and itraconazole. Lancet 1987; 2: 282.
    • (1987) Lancet , vol.2 , pp. 282
    • Kwan, J.T.1    Foxall, P.J.2    Davidson, D.G.3
  • 45
    • 0036227007 scopus 로고    scopus 로고
    • Effect of voriconazole on the pharmacokinetics of cyclosporine in renal transplant patients
    • Romero AJ, Pogamp PL, Nilsson LG, Wood N. Effect of voriconazole on the pharmacokinetics of cyclosporine in renal transplant patients. Clin Pharmacol Ther 2002; 71: 226-234.
    • (2002) Clin. Pharmacol. Ther. , vol.71 , pp. 226-234
    • Romero, A.J.1    Pogamp, P.L.2    Nilsson, L.G.3    Wood, N.4
  • 46
    • 0024854242 scopus 로고
    • The cyclosporine-sparing effects of diltiazem in renal transplantation
    • McCauley J, Ptachcinski RJ, Shapiro R. The cyclosporine-sparing effects of diltiazem in renal transplantation. Transplant Proc 1989; 21: 3955-3957.
    • (1989) Transplant. Proc. , vol.21 , pp. 3955-3957
    • McCauley, J.1    Ptachcinski, R.J.2    Shapiro, R.3
  • 47
    • 0001495754 scopus 로고
    • Cyclosporine and tegretol - Another drug interaction
    • Lele P, Peteson P, Yang S et al. Cyclosporine and tegretol - another drug interaction. Kidney Int 1985; 27: 34.
    • (1985) Kidney Int. , vol.27 , pp. 34
    • Lele, P.1    Peteson, P.2    Yang, S.3
  • 48
    • 0028145333 scopus 로고
    • Cyclosporin-chloramphenicol drug interaction in a heart-lung transplant recipient
    • Steinfort CL, McConachy KA. Cyclosporin-chloramphenicol drug interaction in a heart-lung transplant recipient. Med J Austr 1994; 161: 455.
    • (1994) Med. J. Austr. , vol.161 , pp. 455
    • Steinfort, C.L.1    McConachy, K.A.2
  • 49
    • 0027067753 scopus 로고
    • Alteration of etoposide pharmacokinetics and pharmacodynamics by cyclosporine in a phase I trial to modulate multidrug resistance
    • Lum BL, Kaubisch S, Yahanda AM et al. Alteration of etoposide pharmacokinetics and pharmacodynamics by cyclosporine in a phase I trial to modulate multidrug resistance. J Clin Oncol 1992; 10: 1635-1642.
    • (1992) J. Clin. Oncol. , vol.10 , pp. 1635-1642
    • Lum, B.L.1    Kaubisch, S.2    Yahanda, A.M.3
  • 50
    • 0028856444 scopus 로고
    • Norfloxacin interferes with cyclosporine disposition in pediatric patients undergoing renal transplantation
    • McLellan RA, Drobitch RK, McLellan H et al. Norfloxacin interferes with cyclosporine disposition in pediatric patients undergoing renal transplantation. Clin Pharmacol Ther 1995; 58: 322-327.
    • (1995) Clin. Pharmacol. Ther. , vol.58 , pp. 322-327
    • McLellan, R.A.1    Drobitch, R.K.2    McLellan, H.3
  • 51
    • 0028107355 scopus 로고
    • Does ciprofloxacin interact with cyclosporine?
    • Hoey LL, Lake KD. Does ciprofloxacin interact with cyclosporine? Ann Pharmacother 1994; 28: 93-96.
    • (1994) Ann. Pharmacother. , vol.28 , pp. 93-96
    • Hoey, L.L.1    Lake, K.D.2
  • 52
    • 0031885169 scopus 로고    scopus 로고
    • Levofloxacin does not alter cyclosporine disposition
    • Doose DR, Walker SA, Chien SC et al. Levofloxacin does not alter cyclosporine disposition. J Clin Pharmacol 1998; 38: 90-93.
    • (1998) J. Clin. Pharmacol. , vol.38 , pp. 90-93
    • Doose, D.R.1    Walker, S.A.2    Chien, S.C.3
  • 54
    • 0031051337 scopus 로고    scopus 로고
    • The mechanism of cyclosporine toxicity induced by clarithromycin
    • Spicer ST, Liddle C, Chapman JR et al. The mechanism of cyclosporine toxicity induced by clarithromycin. Br J Clin Pharmacol 1997; 43: 194-196.
    • (1997) Br. J. Clin. Pharmacol. , vol.43 , pp. 194-196
    • Spicer, S.T.1    Liddle, C.2    Chapman, J.R.3
  • 55
    • 0023111222 scopus 로고
    • Erythromycin-cyclosporine interaction in renal transplant recipients
    • Harnett JD, Parfrey PS, Paul MD et al. Erythromycin-cyclosporine interaction in renal transplant recipients. Transplantation 1987; 43: 316-318.
    • (1987) Transplantation , vol.43 , pp. 316-318
    • Harnett, J.D.1    Parfrey, P.S.2    Paul, M.D.3
  • 56
    • 0035189304 scopus 로고    scopus 로고
    • Effect of cyclosporine withdrawal on mycophenolic acid pharmacokinetics in kidney transplant recipients with deteriorating renal function: Preliminary report
    • Shipkova M, Armstrong VW, Kuypers D et al. Effect of cyclosporine withdrawal on mycophenolic acid pharmacokinetics in kidney transplant recipients with deteriorating renal function: preliminary report. Ther Drug Monitor 2001; 23: 717-721.
    • (2001) Ther. Drug Monitor. , vol.23 , pp. 717-721
    • Shipkova, M.1    Armstrong, V.W.2    Kuypers, D.3
  • 57
    • 0024632577 scopus 로고
    • Drug interaction between cyclosporin and phenytoin in allogeneic bone marrow transplantation
    • Schmidt H, Naumann R, Laschonek K et al. Drug interaction between cyclosporin and phenytoin in allogeneic bone marrow transplantation. Bone Marrow Transplant 1989; 4: 212-213.
    • (1989) Bone Marrow Transplant. , vol.4 , pp. 212-213
    • Schmidt, H.1    Naumann, R.2    Laschonek, K.3
  • 58
    • 0021131998 scopus 로고
    • Interaction between phenytoin and cyclosporine following organ transplantation
    • Keown PA, Laupacis A, Carruthers G et al. Interaction between phenytoin and cyclosporine following organ transplantation. Transplantation 1984; 38: 304-306.
    • (1984) Transplantation , vol.38 , pp. 304-306
    • Keown, P.A.1    Laupacis, A.2    Carruthers, G.3
  • 59
    • 0021676745 scopus 로고
    • Evaluation of cyclosporine-phenytoin interaction with observations on cyclosporine metabolites
    • Freeman DL, Laupacis A, Keown PA et al. Evaluation of cyclosporine-phenytoin interaction with observations on cyclosporine metabolites. Br J Clin Pharmacol 1984; 18: 887-893.
    • (1984) Br. J. Clin. Pharmacol. , vol.18 , pp. 887-893
    • Freeman, D.L.1    Laupacis, A.2    Keown, P.A.3
  • 60
    • 0030911808 scopus 로고    scopus 로고
    • Interaction between quinupristin/dalfopristin and cyclosporine
    • Stamatakis MK, Richards JG. Interaction between quinupristin/dalfopristin and cyclosporine. Ann Pharmacother 1997; 31: 576-578.
    • (1997) Ann. Pharmacother. , vol.31 , pp. 576-578
    • Stamatakis, M.K.1    Richards, J.G.2
  • 61
    • 0026457407 scopus 로고
    • Bioavailability of cyclosporine with concomitant rifampin administration is markedly less than predicted by hepatic enzyme induction
    • Hebert MF, Roberts JP, Prueksaritanont T et al. Bioavailability of cyclosporine with concomitant rifampin administration is markedly less than predicted by hepatic enzyme induction. Clin Pharmacol Ther 1992; 52: 453-457.
    • (1992) Clin. Pharmacol. Ther. , vol.52 , pp. 453-457
    • Hebert, M.F.1    Roberts, J.P.2    Prueksaritanont, T.3
  • 62
    • 0022258946 scopus 로고
    • Low cyclosporine A blood levels and acute graft rejection in a renal transplant recipient during rifampin treatment
    • Offerman G, Keller F, Molzahn M. Low cyclosporine A blood levels and acute graft rejection in a renal transplant recipient during rifampin treatment. Am J Nephrol 1985; 5: 385-387.
    • (1985) Am. J. Nephrol. , vol.5 , pp. 385-387
    • Offerman, G.1    Keller, F.2    Molzahn, M.3
  • 63
    • 0021941863 scopus 로고
    • Acute rejection and massive cyclosporine requirements in heart transplant recipients treated with rifampin
    • Modry DL, Stinson EB, Oyer PE et al. Acute rejection and massive cyclosporine requirements in heart transplant recipients treated with rifampin. Transplantation 1985; 39: 313-314.
    • (1985) Transplantation , vol.39 , pp. 313-314
    • Modry, D.L.1    Stinson, E.B.2    Oyer, P.E.3
  • 64
    • 0842271710 scopus 로고    scopus 로고
    • Data on file. Wyeth Pharmaceuticals: Madison, NJ
    • Data on file. Wyeth Pharmaceuticals: Madison, NJ.
  • 65
    • 0034806877 scopus 로고    scopus 로고
    • Interactions of sildenafil and tacrolimus in men with erectile dysfunction after kidney transplantation
    • Christ B, Brockmeier D, Hauck EW et al. Interactions of sildenafil and tacrolimus in men with erectile dysfunction after kidney transplantation. Urology 2001; 58: 589-593.
    • (2001) Urology , vol.58 , pp. 589-593
    • Christ, B.1    Brockmeier, D.2    Hauck, E.W.3
  • 66
    • 0034639638 scopus 로고    scopus 로고
    • Acute heart transplant rejection due to Saint John's wort
    • Ruschitzka F, Meier PJ, Turina M et al. Acute heart transplant rejection due to Saint John's wort. Lancet 2000; 355: 548-549.
    • (2000) Lancet , vol.355 , pp. 548-549
    • Ruschitzka, F.1    Meier, P.J.2    Turina, M.3
  • 67
    • 0034720558 scopus 로고    scopus 로고
    • Profound drop of cyclosporin A whole blood trough levels caused by St John's wort (Hypericum -perforatum)
    • Breidenbach TH, Kliem V, Burg M et al. Profound drop of cyclosporin A whole blood trough levels caused by St John's wort (Hypericum -perforatum). Transplantation 2000; 69: 2229-2230.
    • (2000) Transplantation , vol.69 , pp. 2229-2230
    • Breidenbach, T.H.1    Kliem, V.2    Burg, M.3
  • 68
    • 0033836868 scopus 로고    scopus 로고
    • Drug interaction between St John's wort and cyclosporine
    • Barone GW, Gurley BJ, Ketel BL et al. Drug interaction between St John's wort and cyclosporine. Ann Pharmacother 2000; 34: 1013-1016.
    • (2000) Ann. Pharmacother. , vol.34 , pp. 1013-1016
    • Barone, G.W.1    Gurley, B.J.2    Ketel, B.L.3
  • 69
    • 0034720577 scopus 로고    scopus 로고
    • Drug interaction of St John's wort with cyclosporin
    • Breidenbach T, Hoffmann MW, Becker T et al. Drug interaction of St John's wort with cyclosporin. Lancet 2000; 355: 1912.
    • (2000) Lancet , vol.355 , pp. 1912
    • Breidenbach, T.1    Hoffmann, M.W.2    Becker, T.3
  • 70
    • 0033763121 scopus 로고    scopus 로고
    • Interaction of Hypericum perforatum (St John's wort) with cyclosporin A metabolism in a patient after liver transplantation
    • Karliova M, Treichel V, Malago M et al. Interaction of Hypericum perforatum (St John's wort) with cyclosporin A metabolism in a patient after liver transplantation. J Hepatol 2000; 33: 853-855.
    • (2000) J. Hepatol. , vol.33 , pp. 853-855
    • Karliova, M.1    Treichel, V.2    Malago, M.3
  • 71
    • 0033787159 scopus 로고    scopus 로고
    • Hazardous pharmacokinetic interaction of St John's wort (Hypericum perforatum) with the immunosuppressant cyclosporin
    • Mai I, Kruger H, Budde K et al. Hazardous pharmacokinetic interaction of St John's wort (Hypericum perforatum) with the immunosuppressant cyclosporin. Int J Clin Pharmacol Ther 2000; 38: 500-502.
    • (2000) Int. J. Clin. Pharmacol. Ther. , vol.38 , pp. 500-502
    • Mai, I.1    Kruger, H.2    Budde, K.3
  • 72
    • 0033828635 scopus 로고    scopus 로고
    • Unexplained decrease of cyclosporine trough levels in a compliant renal transplant patient
    • Mandelbaum A, Pertzborn F, Martin-Facklam M et al. Unexplained decrease of cyclosporine trough levels in a compliant renal transplant patient. Nephrol Dial Transplant 2000; 15: 1473.
    • (2000) Nephrol. Dial. Transplant. , vol.15 , pp. 1473
    • Mandelbaum, A.1    Pertzborn, F.2    Martin-Facklam, M.3
  • 73
    • 0036001229 scopus 로고    scopus 로고
    • A clinical pharmacokinetic study of tacrolimus and sirolimus combination immunosuppression comparing simultaneous to separated administration
    • McAlister VC, Mahalati K, Peltekian KM et al. A clinical pharmacokinetic study of tacrolimus and sirolimus combination immunosuppression comparing simultaneous to separated administration. Ther Drug Monit 2002; 24: 346-350.
    • (2002) Ther. Drug Monit. , vol.24 , pp. 346-350
    • McAlister, V.C.1    Mahalati, K.2    Peltekian, K.M.3
  • 74
    • 0029025655 scopus 로고
    • Recent advances: The cytochrome P450 enzymes
    • Slaughter RL, Edwards DJ. Recent advances: the cytochrome P450 enzymes. Ann Pharmacother 1995; 29: 619-624.
    • (1995) Ann. Pharmacother. , vol.29 , pp. 619-624
    • Slaughter, R.L.1    Edwards, D.J.2
  • 75
    • 0028788598 scopus 로고
    • Rifampin-fluconazole interaction in critically ill patients
    • Nicolau DP, Crowe HM, Nightingale CH et al. Rifampin-fluconazole interaction in critically ill patients. Ann Pharmacother 1995; 29: 994-996.
    • (1995) Ann. Pharmacother. , vol.29 , pp. 994-996
    • Nicolau, D.P.1    Crowe, H.M.2    Nightingale, C.H.3
  • 78
    • 0024564717 scopus 로고
    • Fluconazole and phenytoin: A predictable interaction
    • Mitchell AS, Holland JT. Fluconazole and phenytoin: a predictable interaction. Br Med J 1989; 298: 1315.
    • (1989) Br. Med. J. , vol.298 , pp. 1315
    • Mitchell, A.S.1    Holland, J.T.2
  • 79
    • 0024310248 scopus 로고
    • Phenytoin toxicity induced by fluconazole
    • Howitt KM, Oziemski MA. Phenytoin toxicity induced by fluconazole. Med J Austr 1989; 151: 603-604.
    • (1989) Med. J. Austr. , vol.151 , pp. 603-604
    • Howitt, K.M.1    Oziemski, M.A.2
  • 80
    • 0027439883 scopus 로고
    • Low-dose fluconazole therapy potentiates the hypoprothrombinemic response of warfarin sodium
    • Crussell-Porter LL, Rindone JP, Ford MA et al. Low-dose fluconazole therapy potentiates the hypoprothrombinemic response of warfarin sodium. Arch Intern Med 1993; 153: 102-104.
    • (1993) Arch. Intern. Med. , vol.153 , pp. 102-104
    • Crussell-Porter, L.L.1    Rindone, J.P.2    Ford, M.A.3
  • 81
    • 0029996292 scopus 로고    scopus 로고
    • Warfarin-fluconazole. II. A metabolically based drug interaction: In vivo studies
    • Black DJ, Kunze KL, Wienkers LC et al. Warfarin-fluconazole. II. A metabolically based drug interaction: in vivo studies. Drug Metab Dispos 1996; 24: 422-428.
    • (1996) Drug Metab. Dispos. , vol.24 , pp. 422-428
    • Black, D.J.1    Kunze, K.L.2    Wienkers, L.C.3
  • 83
    • 0027452362 scopus 로고
    • Possible interaction between warfarin and fluconazole
    • Gericke KR. Possible interaction between warfarin and fluconazole. Pharmacotherapy 1993; 13: 508-509.
    • (1993) Pharmacotherapy , vol.13 , pp. 508-509
    • Gericke, K.R.1
  • 84
    • 0025061742 scopus 로고
    • Potentiation of action of warfarin by itraconazole
    • Yeh J, Soo SC, Summerton C et al. Potentiation of action of warfarin by itraconazole. Br Med J 1990; 301: 669.
    • (1990) Br. Med. J. , vol.301 , pp. 669
    • Yeh, J.1    Soo, S.C.2    Summerton, C.3
  • 85
    • 0027385194 scopus 로고
    • Syncope and cardiac arrhythmia due to an interaction between itraconazole and terfenadine
    • Crane JK, Shih HT. Syncope and cardiac arrhythmia due to an interaction between itraconazole and terfenadine. Am J Med 1993; 95: 445-446.
    • (1993) Am. J. Med. , vol.95 , pp. 445-446
    • Crane, J.K.1    Shih, H.T.2
  • 86
    • 0027092302 scopus 로고
    • Torsades de pointes after terfenadine-itraconazole interaction
    • Pohjola-Sintonen S, Viitasalo M, Toivonene L et al. Torsades de pointes after terfenadine-itraconazole interaction. Br Med J 1993; 306: 186.
    • (1993) Br. Med. J. , vol.306 , pp. 186
    • Pohjola-Sintonen, S.1    Viitasalo, M.2    Toivonene, L.3
  • 87
    • 17944376229 scopus 로고    scopus 로고
    • Potentiation of vincristine toxicity by itraconazole in children with lymphoid malignancies
    • Kamaluddin M, McNally P, Breatnach F et al. Potentiation of vincristine toxicity by itraconazole in children with lymphoid malignancies. Acta Paediatr 2001; 90: 1204-1207.
    • (2001) Acta Paediatr. , vol.90 , pp. 1204-1207
    • Kamaluddin, M.1    McNally, P.2    Breatnach, F.3
  • 88
    • 0035112762 scopus 로고    scopus 로고
    • Itraconazole-enhanced vincristine neurotoxicity in a child with acute lymphoblastic leukemia
    • Jeng MR, Feusner J. Itraconazole-enhanced vincristine neurotoxicity in a child with acute lymphoblastic leukemia. Pediatr Hematol Oncol 2001; 18: 137-142.
    • (2001) Pediatr. Hematol. Oncol. , vol.18 , pp. 137-142
    • Jeng, M.R.1    Feusner, J.2
  • 89
    • 0035199988 scopus 로고    scopus 로고
    • Enhanced vincristine neurotoxicity from drug interactions: Case report and review of the literature
    • Sathiapalan RK, El-Solh H. Enhanced vincristine neurotoxicity from drug interactions: case report and review of the literature. Pediatr Hematol Oncol 2001; 18: 543-546.
    • (2001) Pediatr. Hematol. Oncol. , vol.18 , pp. 543-546
    • Sathiapalan, R.K.1    El-Solh, H.2
  • 90
    • 0029615492 scopus 로고
    • Aggravation of vincristine-induced neurotoxicity by itraconazole in the treatment of adult ALL
    • Bohme A, Ganser A, Hoelzer D. Aggravation of vincristine-induced neurotoxicity by itraconazole in the treatment of adult ALL. Ann Hematol 1995; 71: 311-312.
    • (1995) Ann. Hematol. , vol.71 , pp. 311-312
    • Bohme, A.1    Ganser, A.2    Hoelzer, D.3
  • 91
    • 0029095956 scopus 로고
    • Vincristine toxicity in five children with acute lymphoblastic leukaemia
    • Murphy JA, Ross LM, Gibson BE. Vincristine toxicity in five children with acute lymphoblastic leukaemia. Lancet 1995; 346: 443.
    • (1995) Lancet , vol.346 , pp. 443
    • Murphy, J.A.1    Ross, L.M.2    Gibson, B.E.3
  • 92
    • 0028357256 scopus 로고
    • Midazolam should be avoided in patients receiving systemic antimycotics ketoconazole or itraconazole
    • Olkkola KT, Backman JT, Neuvonen PJ. Midazolam should be avoided in patients receiving systemic antimycotics ketoconazole or itraconazole. Clin Pharmacol Ther 1994; 55: 481-485.
    • (1994) Clin. Pharmacol. Ther. , vol.55 , pp. 481-485
    • Olkkola, K.T.1    Backman, J.T.2    Neuvonen, P.J.3
  • 93
    • 0028568243 scopus 로고
    • Oral triazolam is potentially hazardous to patients receiving systemic antimycotics ketoconazole or itraconazole
    • Varhe A, Olkkola KT, Neuvonen PJ. Oral triazolam is potentially hazardous to patients receiving systemic antimycotics ketoconazole or itraconazole. Clin Pharmacol Ther 1994; 56: 601-607.
    • (1994) Clin. Pharmacol. Ther. , vol.56 , pp. 601-607
    • Varhe, A.1    Olkkola, K.T.2    Neuvonen, P.J.3
  • 94
    • 0030898365 scopus 로고    scopus 로고
    • Itraconazole greatly increases plasma concentrations and effects of felodipine
    • Jalalava KM, Olkkola KT, Neuvonen PJ. Itraconazole greatly increases plasma concentrations and effects of felodipine. Clin Pharmacol Ther 1997; 61: 410-415.
    • (1997) Clin. Pharmacol. Ther. , vol.61 , pp. 410-415
    • Jalalava, K.M.1    Olkkola, K.T.2    Neuvonen, P.J.3
  • 95
    • 0026531324 scopus 로고
    • Interaction of azoles with rifampin, phenytoin, and carbamazepine: In vitro and clinical observations
    • Tucker RM, Denning DW, Hanson LH et al. Interaction of azoles with rifampin, phenytoin, and carbamazepine: in vitro and clinical observations. Clin Infect Dis 1992; 14: 165-174.
    • (1992) Clin. Infect. Dis. , vol.14 , pp. 165-174
    • Tucker, R.M.1    Denning, D.W.2    Hanson, L.H.3
  • 96
    • 0027384591 scopus 로고
    • Possible interaction between phenobarbital, carbamazepine and itraconazole
    • Bonay M, Jonville-Bera AP, Diot P et al. Possible interaction between phenobarbital, carbamazepine and itraconazole. Drug Saf 1993; 9: 309-311.
    • (1993) Drug Saf. , vol.9 , pp. 309-311
    • Bonay, M.1    Jonville-Bera, A.P.2    Diot, P.3
  • 97
    • 0030946590 scopus 로고    scopus 로고
    • Digoxin-itraconazole interaction: Possible mechanisms
    • Alderman CP, Allcroft PD. Digoxin-itraconazole interaction: possible mechanisms. Ann Pharmacother 1997; 31: 438-440.
    • (1997) Ann. Pharmacother. , vol.31 , pp. 438-440
    • Alderman, C.P.1    Allcroft, P.D.2
  • 99
    • 0026552481 scopus 로고
    • Itraconazole-digoxin interaction
    • Rex J. Itraconazole-digoxin interaction. Ann Intern Med 1992; 116: 525.
    • (1992) Ann. Intern. Med. , vol.116 , pp. 525
    • Rex, J.1
  • 100
    • 0026442315 scopus 로고
    • Digoxin toxicity associated with itraconazole therapy
    • Kauffman CA, Bagnasco FA. Digoxin toxicity associated with itraconazole therapy. Clin Infect Dis 1992; 15: 886-887.
    • (1992) Clin. Infect. Dis. , vol.15 , pp. 886-887
    • Kauffman, C.A.1    Bagnasco, F.A.2
  • 101
    • 0029758869 scopus 로고    scopus 로고
    • Itraconazole drastically increases plasma concentrations of lovastatin and lovastatin acid
    • Neuvonen PJ, Jalava KM. Itraconazole drastically increases plasma concentrations of lovastatin and lovastatin acid. Clin Pharmacol Ther 1996; 60: 54-61.
    • (1996) Clin. Pharmacol. Ther. , vol.60 , pp. 54-61
    • Neuvonen, P.J.1    Jalava, K.M.2
  • 102
  • 103
    • 0031892901 scopus 로고    scopus 로고
    • Simvastatin but not pravastatin is very susceptible to interactions with the CYP3A4 inhibitor itraconazole
    • Neuvonen PJ, Kantola T, Kivisto KJ. Simvastatin but not pravastatin is very susceptible to interactions with the CYP3A4 inhibitor itraconazole. Clin Pharmacol Ther 1998; 63: 332-341.
    • (1998) Clin. Pharmacol. Ther. , vol.63 , pp. 332-341
    • Neuvonen, P.J.1    Kantola, T.2    Kivisto, K.J.3
  • 104
    • 0037182837 scopus 로고    scopus 로고
    • Itraconazole-induced rhabdomyolysis and acute renal failure in a heart transplant recipient treated with simvastatin and cyclosporine
    • Vlahakos DV, Manginas A, Chilidou D et al. Itraconazole-induced rhabdomyolysis and acute renal failure in a heart transplant recipient treated with simvastatin and cyclosporine. Transplantation 2002; 73: 1962-1964.
    • (2002) Transplantation , vol.73 , pp. 1962-1964
    • Vlahakos, D.V.1    Manginas, A.2    Chilidou, D.3
  • 105
    • 0029595358 scopus 로고
    • Itraconazole and hydroxyitraconazole serum concentrations are reduced more than tenfold by phenytoin
    • Ducharme MP, Slaughter RL, Warnasse LH et al. Itraconazole and hydroxyitraconazole serum concentrations are reduced more than tenfold by phenytoin. Clin Pharmacol Ther 1995; 58: 617-624.
    • (1995) Clin. Pharmacol. Ther. , vol.58 , pp. 617-624
    • Ducharme, M.P.1    Slaughter, R.L.2    Warnasse, L.H.3
  • 106
    • 0031900228 scopus 로고    scopus 로고
    • Effect of rifampicin on the pharmacokinetics of itraconazole in normal volunteers and AIDS patients
    • Jaruratanasirikul S, Sriwiriyajan S. Effect of rifampicin on the pharmacokinetics of itraconazole in normal volunteers and AIDS patients. Eur J Clin Pharmacol 1998; 54: 155-158.
    • (1998) Eur. J. Clin. Pharmacol. , vol.54 , pp. 155-158
    • Jaruratanasirikul, S.1    Sriwiriyajan, S.2
  • 107
    • 0028009473 scopus 로고
    • Coadministration of rifampin and itraconazole leads to undetectable levels of serum itraconazole
    • Drayton J, Dickinson G, Rinaldi MG. Coadministration of rifampin and itraconazole leads to undetectable levels of serum itraconazole. Clin Infect Dis 1994; 18: 266-267.
    • (1994) Clin. Infect. Dis. , vol.18 , pp. 266-267
    • Drayton, J.1    Dickinson, G.2    Rinaldi, M.G.3
  • 109
    • 0003690790 scopus 로고    scopus 로고
    • Definition of an itraconazole target concentration for antifungal prophylaxis
    • Toronto, Ontario, 17-20 September 2000 (abstract 700). American Society of Microbiology: Washington, DC
    • Glasmacher A, Hahn C, Molitor E et al. Definition of an itraconazole target concentration for antifungal prophylaxis. In: Program and Abstracts of the 40th Interscience Conference on Antimicrobial Agents and Chemotherapy, Toronto, Ontario, 17-20 September 2000 (abstract 700). American Society of Microbiology: Washington, DC, 2000.
    • (2000) Program and Abstracts of the 40th Interscience Conference on Antimicrobial Agents and Chemotherapy
    • Glasmacher, A.1    Hahn, C.2    Molitor, E.3
  • 110
    • 0032914402 scopus 로고    scopus 로고
    • The effect of fluconazole on cyclophosphamide metabolism in children
    • Yule SM, Walker D, Cole M et al. The effect of fluconazole on cyclophosphamide metabolism in children. Drug Metab Dispos 1999; 27: 417-421.
    • (1999) Drug Metab. Dispos. , vol.27 , pp. 417-421
    • Yule, S.M.1    Walker, D.2    Cole, M.3
  • 111
    • 9444277948 scopus 로고    scopus 로고
    • Itraconazole can increase systemic exposure to busulfan in patients given bone marrow transplantation
    • GITMO (Gruppo Italiano Trapianto di Midollo Osseo)
    • Buggia I, Zecca M, Alessandrino EP et al. Itraconazole can increase systemic exposure to busulfan in patients given bone marrow transplantation. GITMO (Gruppo Italiano Trapianto di Midollo Osseo). Anticancer Res 1996; 16: 2083-2088.
    • (1996) Anticancer Res. , vol.16 , pp. 2083-2088
    • Buggia, I.1    Zecca, M.2    Alessandrino, E.P.3
  • 112
    • 0842336340 scopus 로고    scopus 로고
    • Data on file. Pfizer Inc.: New York, NY
    • Data on file. Pfizer Inc.: New York, NY.
  • 119
    • 0037099535 scopus 로고    scopus 로고
    • Modulation of irinotecan metabolism by ketoconazole
    • Kehrer DF, Mathijssen RH, Verweij J et al. Modulation of irinotecan metabolism by ketoconazole. J Clin Oncol 2002; 20: 3122-3129.
    • (2002) J. Clin. Oncol. , vol.20 , pp. 3122-3129
    • Kehrer, D.F.1    Mathijssen, R.H.2    Verweij, J.3
  • 120
    • 0003339063 scopus 로고    scopus 로고
    • A Phase I study of caspofungin evaluating the potential for drug interactions with itraconazole, the effect of gender and the use of a loading dose regimen
    • Toronto, Ontario, 17-20 September 2000 (abstract 854). American Society of Microbiology: Washington, DC
    • Stone JA, McCrea JB, Wickersham PJ et al. A Phase I study of caspofungin evaluating the potential for drug interactions with itraconazole, the effect of gender and the use of a loading dose regimen. In: Program and Abstracts of the 40th Interscience Conference on Antimicrobial Agents and Chemotherapy, Toronto, Ontario, 17-20 September 2000 (abstract 854). American Society of Microbiology: Washington, DC, 2000.
    • (2000) Program and Abstracts of the 40th Interscience Conference on Antimicrobial Agents and Chemotherapy
    • Stone, J.A.1    McCrea, J.B.2    Wickersham, P.J.3
  • 121
    • 0842314847 scopus 로고    scopus 로고
    • Data on file. Merck and Co.: Whitehouse Station, NJ
    • Data on file. Merck and Co.: Whitehouse Station, NJ.
  • 123
    • 0042132170 scopus 로고    scopus 로고
    • Randomized, double-blind trial of micafungin (MI) versus fluconazole (FL) for prophylaxis of invasive fungal infections in patients (pts) undergoing hematopoietic stem cell transplant (HSCT), NIAID/BAMSG Protocol 46
    • San Diego, CA, 27-30 September 2002 (abstract M-1238). Washington, DC: American Society of Microbiology
    • Van Burik J, Ratanatharathorn V, Lipton J et al. Randomized, double-blind trial of micafungin (MI) versus fluconazole (FL) for prophylaxis of invasive fungal infections in patients (pts) undergoing hematopoietic stem cell transplant (HSCT), NIAID/BAMSG Protocol 46. In: Program and Abstracts of the 42nd Interscience Conference on Antimicrobial Agents and Chemotherapy, San Diego, CA, 27-30 September 2002 (abstract M-1238). Washington, DC: American Society of Microbiology, 2002.
    • (2002) Program and Abstracts of the 42nd Interscience Conference on Antimicrobial Agents and Chemotherapy
    • Van Burik, J.1    Ratanatharathorn, V.2    Lipton, J.3
  • 124
    • 0036073540 scopus 로고    scopus 로고
    • Food-drug interactions
    • Schmidt LE, Dalhoff K. Food-drug interactions. Drugs 2002; 62: 1481-1502.
    • (2002) Drugs , vol.62 , pp. 1481-1502
    • Schmidt, L.E.1    Dalhoff, K.2
  • 125
    • 0034751938 scopus 로고    scopus 로고
    • Effect of grapefruit juice on digoxin pharmacokinetics in humans
    • Becquemont L, Verstuyft C, Kerb R et al. Effect of grapefruit juice on digoxin pharmacokinetics in humans. Clin Pharmacol Ther 2001; 70: 311-316.
    • (2001) Clin. Pharmacol. Ther. , vol.70 , pp. 311-316
    • Becquemont, L.1    Verstuyft, C.2    Kerb, R.3
  • 126
    • 0033831256 scopus 로고    scopus 로고
    • Drug-grapefruit juice interactions
    • Kane GC, Lipsky JJ. Drug-grapefruit juice interactions. Mayo Clin Proc 2000; 75: 933-942.
    • (2000) Mayo Clin. Proc. , vol.75 , pp. 933-942
    • Kane, G.C.1    Lipsky, J.J.2
  • 127
    • 0013521181 scopus 로고
    • Pharmacokinetics and cardiac effects of terfenadine in poor metabolizers receiving concomitant grapefruit juice
    • Honig PK, Wortham DC, Lazarev A et al. Pharmacokinetics and cardiac effects of terfenadine in poor metabolizers receiving concomitant grapefruit juice. Clin Pharmacol Ther 1995; 57: 185.
    • (1995) Clin. Pharmacol. Ther. , vol.57 , pp. 185
    • Honig, P.K.1    Wortham, D.C.2    Lazarev, A.3
  • 128
    • 0013506202 scopus 로고
    • Inhibition of terfenadine metabolism by co-administration of grapefruit juice in humans
    • Rau SE, Bend JF, Tran LT et al. Inhibition of terfenadine metabolism by co-administration of grapefruit juice in humans. Clin Invest Med 1995; 18: 95.
    • (1995) Clin. Invest. Med. , vol.18 , pp. 95
    • Rau, S.E.1    Bend, J.F.2    Tran, L.T.3
  • 130
    • 0029101508 scopus 로고
    • Plasma concentrations of triazolam are increased by concomitant ingestion of grapefruit juice
    • Hukkinen SK, Varhe A, Olkkola KT et al. Plasma concentrations of triazolam are increased by concomitant ingestion of grapefruit juice. Clin Pharmacol Ther 1995; 58: 127-131.
    • (1995) Clin. Pharmacol. Ther. , vol.58 , pp. 127-131
    • Hukkinen, S.K.1    Varhe, A.2    Olkkola, K.T.3
  • 131
    • 0033748423 scopus 로고    scopus 로고
    • Lack of effect of grapefruit juice on the pharmacokinetics and pharmacodynamics of amlodipine
    • Vincent J, Harris SI, Foulds G et al. Lack of effect of grapefruit juice on the pharmacokinetics and pharmacodynamics of amlodipine. Br J Clin Pharmacol 2000; 50: 455-463.
    • (2000) Br. J. Clin. Pharmacol. , vol.50 , pp. 455-463
    • Vincent, J.1    Harris, S.I.2    Foulds, G.3
  • 133
    • 0029055363 scopus 로고
    • Disposition of intravenous and oral cyclosporine after administration with grapefruit juice
    • Ducharme MP, Warbasse LH, Edwards DJ. Disposition of intravenous and oral cyclosporine after administration with grapefruit juice. Clin Pharmacol Ther 1995; 57: 485-491.
    • (1995) Clin. Pharmacol. Ther. , vol.57 , pp. 485-491
    • Ducharme, M.P.1    Warbasse, L.H.2    Edwards, D.J.3
  • 134
    • 0028963036 scopus 로고
    • Effect of grapefruit juice on blood cyclosporin concentration
    • Yee GC, Stanley DL, Pessa JL et al. Effect of grapefruit juice on blood cyclosporin concentration. Lancet 1995; 345: 955-956.
    • (1995) Lancet , vol.345 , pp. 955-956
    • Yee, G.C.1    Stanley, D.L.2    Pessa, J.L.3
  • 135
    • 0029890499 scopus 로고    scopus 로고
    • Effect of grapefruit juice on cyclosporine pharmacokinetics in renal transplant patients
    • Min DI, Ku YM, Perry PJ et al. Effect of grapefruit juice on cyclosporine pharmacokinetics in renal transplant patients. Transplantation 1996, 62: 123-125.
    • (1996) Transplantation , vol.62 , pp. 123-125
    • Min, D.I.1    Ku, Y.M.2    Perry, P.J.3
  • 136
    • 0031985096 scopus 로고    scopus 로고
    • Interaction between cyclosporine and grapefruit juice requires long-term ingestion in stable renal transplant recipients
    • Brunner LJ, Munar MY, Vallian J et al. Interaction between cyclosporine and grapefruit juice requires long-term ingestion in stable renal transplant recipients. Pharmacotherapy 1998; 18: 23-29.
    • (1998) Pharmacotherapy , vol.18 , pp. 23-29
    • Brunner, L.J.1    Munar, M.Y.2    Vallian, J.3
  • 137
    • 0031964850 scopus 로고    scopus 로고
    • Clinical interaction between grapefruit juice and cyclosporine: Is there any interest for the hematologists?
    • Emilia G, Longo G, Bertesi M et al. Clinical interaction between grapefruit juice and cyclosporine: is there any interest for the hematologists? Blood 1998; 91: 362-363.
    • (1998) Blood , vol.91 , pp. 362-363
    • Emilia, G.1    Longo, G.2    Bertesi, M.3
  • 138
    • 0031025964 scopus 로고    scopus 로고
    • Dosing implications of a clinical interaction between grapefruit juice and cyclosporine and metabolite concentrations in patients with autoimmune diseases
    • Ioannides-Demnos LL, Christophidis N, Ryan P et al. Dosing implications of a clinical interaction between grapefruit juice and cyclosporine and metabolite concentrations in patients with autoimmune diseases. J Rheumatol 1997; 24: 49-54.
    • (1997) J. Rheumatol. , vol.24 , pp. 49-54
    • Ioannides-Demnos, L.L.1    Christophidis, N.2    Ryan, P.3
  • 139
    • 0024854242 scopus 로고
    • The cyclosporine-sparing effects of diltiazem in renal transplantation
    • McCauley J, Ptachcinski RJ, Shapiro R. The cyclosporine-sparing effects of diltiazem in renal transplantation. Transplant Proc 1989; 21: 3955-3957.
    • (1989) Transplant. Proc. , vol.21 , pp. 3955-3957
    • McCauley, J.1    Ptachcinski, R.J.2    Shapiro, R.3
  • 140
    • 0028326841 scopus 로고
    • A preliminary report of diltiazem and ketoconazole. Their cyclosporine sparing effect and impact on transplant outcomes
    • Patton PR, Brunson ME, Pfaff WW et al. A preliminary report of diltiazem and ketoconazole. Their cyclosporine sparing effect and impact on transplant outcomes. Transplantation 1994; 57: 889-892.
    • (1994) Transplantation , vol.57 , pp. 889-892
    • Patton, P.R.1    Brunson, M.E.2    Pfaff, W.W.3
  • 141
    • 0032900516 scopus 로고    scopus 로고
    • The clinical and economic potential of cyclosporin drug interactions
    • Martin JE, Daoud AJ, Schroeder TJ et al. The clinical and economic potential of cyclosporin drug interactions. Pharmacoeconomics 1999; 15: 317-337.
    • (1999) Pharmacoeconomics , vol.15 , pp. 317-337
    • Martin, J.E.1    Daoud, A.J.2    Schroeder, T.J.3
  • 142
    • 0031426283 scopus 로고    scopus 로고
    • Survey of alternative medicine use among organ transplant patients
    • Crone CC, Wise TN. Survey of alternative medicine use among organ transplant patients. J Transplant Coord 1997; 7: 123-130.
    • (1997) J. Transplant. Coord. , vol.7 , pp. 123-130
    • Crone, C.C.1    Wise, T.N.2
  • 143
    • 0032508952 scopus 로고    scopus 로고
    • Trends in alternative medicine use in the United States, 1990-1997: Results of a follow-up national survey
    • Eisenberg DM, Davis RB, Ettner SL. Trends in alternative medicine use in the United States, 1990-1997: results of a follow-up national survey. JAMA 1998; 280: 1569-1575.
    • (1998) JAMA , vol.280 , pp. 1569-1575
    • Eisenberg, D.M.1    Davis, R.B.2    Ettner, S.L.3
  • 144
    • 0030055770 scopus 로고    scopus 로고
    • St John's wort for depression: An overview and meta-analysis of randomised clinical trials
    • Linde K, Ramirez G, Mulrow CD et al. St John's wort for depression: an overview and meta-analysis of randomised clinical trials. Br Med J 1996; 313: 253-258.
    • (1996) Br. Med. J. , vol.313 , pp. 253-258
    • Linde, K.1    Ramirez, G.2    Mulrow, C.D.3


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