Macrophage hypo-responsiveness to interferon-γ in aged mice is associated with impaired signaling through Jak-STAT

Mechanisms of Ageing and Development

Volumn 125, Issue 2, 2004, Pages 137-143

  Yoon, P ^a   Keylock, K T ^a   Hartman, M E ^a   Freund, G G ^a   Woods, J A ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

Aging; Classical activation; Interferon ; Macrophage; STAT 1

Indexed keywords

GAMMA INTERFERON; GAMMA INTERFERON RECEPTOR; JANUS KINASE; PROTEIN SUBUNIT; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; STAT1 PROTEIN; TYROSINE;

AGED; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; CELL STIMULATION; CONFERENCE PAPER; CONTROLLED STUDY; GENE EXPRESSION; MACROPHAGE; MALE; MICROBIAL ACTIVITY; MOUSE; MOUSE STRAIN; NONHUMAN; PERITONEUM; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PURIFICATION; REDUCTION; SIGNAL TRANSDUCTION; TUMOR; WESTERN BLOTTING;

EID: 0842302961     PISSN: 00476374     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mad.2003.11.010     Document Type: Conference Paper

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