Characteristic alteration of monocytes with increased intracellular IL-10 and IL-12 in patients with advanced-stage gastric cancer

Journal of Surgical Research

Volumn 116, Issue 2, 2004, Pages 277-287

  Sugai, Hidemitsu ^a   Kono, Koji ^a   Takahashi, Akihiro ^a   Ichihara, Fumiko ^a   Kawaida, Hiromitsu ^a   Fujii, Hideki ^a   Matsumoto, Yoshiro ^a  

^a UNIVERSITY OF YAMANASHI   (Japan)

Author keywords

Gastric cancer; Intracellular cytokine; Monocytes; Vascular endothelial growth factor

Indexed keywords

INTERLEUKIN 10; INTERLEUKIN 12; LYMPHOCYTE SURFACE MARKER; NEUTRALIZING ANTIBODY; OXYGEN; VASCULOTROPIN;

ARTICLE; BLOOD; COMPARATIVE STUDY; CORRELATION ANALYSIS; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DISEASE COURSE; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDIATOR RELEASE; MONOCYTE; PHENOMENOLOGY; PLASMA; PRIORITY JOURNAL; STOMACH CANCER;

EID: 0842285547     PISSN: 00224804     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jss.2003.10.008     Document Type: Article

References (39)

1. Schrier P.I., Peltenburg L.T. Relationship between myc oncogene activation and MHC class I expression. Adv. Cancer Res. 60:1993;181.
2. Garrido F., Cabrera T., Concha A., Glew S., Ruiz-Cabello F., Stern P.L. Natural history of HLA expression during tumour development. Immunol. Today. 14:1993;491.
3. Tanaka Y., Tevethia S.S. In vitro selection of SV40 T antigen epitope loss variants by site-specific cytotoxic T lymphocyte clones. J. Immunol. 140:1988;4348.
4. Restifo N.P., Esquivel F., Kawakami Y., Yewdell J.W., Mule J.J., Rosenberg S.A., Bennink J.R. Identification of human cancers deficient in antigen processing. J. Exp. Med. 177:1993;265.
5. Tada T., Ohzeki S., Utsumi K., Takiuchi H., Muramatsu M., Li X.F., Shimizu J., Fujiwara H., Hamaoka T. Transforming growth factor-beta-induced inhibition of T cell function. Susceptibility difference in T cells of various phenotypes and functions and its relevance to immunosuppression in the tumor-bearing state. J. Immunol. 146:1991;1077.
6. Matsuda M., Salazar F., Petersson M., Masucci G., Hansson J., Pisa P., Zhang Q.J., Masucci M.G., Kiessling R. Interleukin 10 pretreatment protects target cells from tumor- and allo-specific cytotoxic T cells and downregulates HLA-class I expression. J. Exp. Med. 180:1994;2371.
7. Finke J.H., Zea A.H., Stanley J., Longo D.L., Mizoguchi H., Tubbs R.R., Wiltrout R.H., O'Shea J.J., Kudoh S., Klein E., Bukowski R.M., Ochoa A.C. Loss of T cell receptor zeta chain and p56lck in T cells infiltrating human renal cell carcinoma. Cancer Res. 53:1993;5613.
8. Nakagomi H., Petersson M., Magnusson I., Juhlin C., Matsuda M., Mellstedt H., Taupin J.L., Vivier E., Anderson P., Kiessling R. Decreased expression of the signal-transducing zeta chains in tumor-infiltrating T cells and NK cells of patients with colorectal carcinoma. Cancer Res. 53:1993;5610.
9. Zea A.H., Curti B.D., Longo D.L., Alvord W.G., Strobl S.L., Mizoguchi H., Creekmore S.P., O'Shea J.J., Powers G.C., Urba W.J., Ochoa A.C. Alterations in T cell receptor and signal transduction molecules in melanoma patients. Clin. Cancer Res. 1:1995;1327.
10. Kono K., Ressing M.E., Brandt R.M., Melief C.J., Potkul R.K., Andersson B., Petersson M., Kast W.M., Kiessling R. Decreased expression of signal-transducing zeta chain in peripheral T cells and natural killer cells in patients with cervical cancer. Clin. Cancer Res. 2:1996;1825.
11. Lai P., Rabinowich H., Crowley-Nowick P.A., Bell M.C., Mantovani G., Whiteside T.L. Alterations in expression and function of signal-transducing proteins in tumor-associated T and natural killer cells in patients with ovarian carcinoma. Clin. Cancer Res. 2:1996;161.
12. Reichert T.E., Day R., Wagner E.M., Whiteside T.L. Absent or low expression of the zeta chain in T cells at the tumor site correlates with poor survival in patients with oral carcinoma. Cancer Res. 58:1998;5344.
13. Saito T., Kuss I., Dworacki G., Gooding W., Johnson J.T., Whiteside T.L. Spontaneous ex vivo apoptosis of peripheral blood mononuclear cells in patients with head and neck cancer. Clin. Cancer Res. 5:1999;1263.
14. Takahashi A., Kono K., Amemiya H., Iizuka H., Fujii H., Matsumoto Y. Elevated caspase-3 activity in peripheral blood T cells coexists with increased degree of T cell apoptosis and down-regulation of TCR zeta molecules in patients with gastric cancer. Clin. Cancer Res. 7:2001;74.
15. Rabinowich H., Reichert T.E., Kashii Y., Gastman B.R., Bell M.C., Whiteside T.L. Lymphocyte apoptosis induced by Fas ligand-expressing ovarian carcinoma cells. J. Clin. Invest. 101:1998;2579.
16. Gastman B.R., Johnson D.E., Whiteside T.L., Rabinowich H. Caspase-mediated degradation of T cell receptor zeta-chain. Cancer Res. 59:1999;1422.
17. Otsuji M., Kimura Y., Aoe T., Okamoto Y., Saito T. Oxidative stress by tumor-derived macrophages suppresses the expression of CD3 zeta chain of T cell receptor complex and antigen-specific T-cell responses. Proc. Natl. Acad. Sci. USA. 93:1996;13119.
18. Kono K., Salazar-Onfray F., Petersson M., Hansson J., Masucci G., Wasserman K., Nakazawa T., Anderson P., Kiessling R. Hydrogen peroxide secreted by tumor-derived macrophages down-modulates signal-transducing zeta molecules and inhibits tumor-specific T cell- and natural killer cell-mediated cytotoxicity. Eur. J. Immunol. 26:1996;1308.
19. Takahashi A., Kono K., Sugai H., Ichihara F., Amemiya H., Iizuka H., Fujii H., Matsumoto Y. Macrophages in tumor-draining lymph node with different characteristics induce T cell apoptosis in patients with advanced stage-gastric cancer. Int. J. Cancer. 104:2003;393.
20. Macrophage heterogeneity. Heppner G.H., Fulton A.M. Macrophages and Cancer. 1988;1-6 CRC Press, Boca Raton, FL.
21. Munn D.H., Armstrong E. Cytokine regulation of human monocyte differentiation in vitro The tumor-cytotoxic phenotype induced by macrophage colony-stimulating factor is developmentally regulated by gamma-interferon . Cancer Res. 53:1993;2603.
22. Dobashi K., Aihara M., Araki T., Shimizu Y., Utsugi M., Iizuka K., Murata Y., Hamuro J., Nakazawa T., Mori M. Regulation of LPS induced IL-12 production by IFN-gamma and IL-4 through intracellular glutathione status in human alveolar macrophages. Clin. Exp. Immunol. 124:2001;290-296.
23. Kono K., Sekikawa T., Matsumoto Y. Influence of surgical stress on monocytes and complications of infection in patients with esophageal cancer-monocyte HLA-DR antigen expression and respiratory burst capacity. J. Surg. Res. 58:1995;275.
24. Muller W.A. New mechanisms and pathways for monocyte recruitment. J. Exp. Med. 194:2001;47.
25. Hsieh C.S., Heimberger A.B., Gold J.S., O'Garra A., Murphy K.M. Differential regulation of T helper phenotype development by interleukins 4 and 10 in an alpha beta T cell-receptor transgenic system. Proc. Natl. Acad. Sci. USA. 89:1992;6065.
26. Karpus W.J., Swanborg R.H. CD4+ suppressor cells differentially affect the production of IFN-gamma by effector cells of experimental autoimmune encephalomyelitis. J. Immunol. 143:1989;3492.
27. Rincon M., Anguita J., Nakamura T., Fikrig E., Flavell R.A. Interleukin (IL)-6 directs the differentiation of IL-4-producing CD4+ T cells. J. Exp. Med. 185:1997;461.
28. Maloney J.P., Silliman C.C., Ambruso D.R., Wang J., Tuder R.M., Voelkel N.F. In vitro release of vascular endothelial growth factor during platelet aggregation. Am. J. Physiol. 275:1998;1054.
29. Barleon B., Sozzani S., Zhou D., Weich H.A., Mantovani A., Marme D. Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1. Blood. 87:1996;3336.
30. Lavena P., Piemonti L., Longoni D., Bernasconi S., Stoppacciaro A., Ruco L., Mantovani A. IL-10 prevents the differentiation of monocytes to dendritic cells but promotes their maturation to macrophages. Eur. J. Immunol. 28:1998;359.
31. Vaday G.G., Schor H., Rahat M.A., Lahat N., Lider O. Transforming growth factor-beta suppresses tumor necrosis factor alpha-induced matrix metalloproteinase-9 expression in monocytes. J. Leukoc. Biol. 69:2001;613.
32. Leung D.W., Cachianes G., Kuang W.J., Goeddel D.V., Ferrara N. Vascular endothelial growth factor is a secreted angiogenic mitogen. Science. 246:1989;1306.
33. Connolly D.T., Heuvelman D.M., Nelson R., Olander J.V., Eppley B.L., Delfino J.J., Siegel N.R., Leimgruber R.M., Feder J. Tumor vascular permeability factor stimulates endothelial cell growth and angiogenesis. J. Clin. Invest. 84:1989;1470.
34. Kaya M., Wada T., Akatsuka T., Kawaguchi S., Nagoya S., Shindoh M., Higashino F., Mezawa F., Okada F., Ishii S. Vascular endothelial growth factor expression in untreated osteosarcoma is predictive of pulmonary metastasis and poor prognosis. Clin. Cancer Res. 6:2000;572.
35. Saito H., Tsujitani S., Ikeguchi M., Maeta M., Kaibara N. Relationship between the expression of vascular endothelial growth factor and the density of dendritic cells in gastric adenocarcinoma tissue. Br. J. Cancer. 78:1998;1573-1577.
36. Miyake M., Taki T., Hitomi S., Hakomori S. Correlation of expression of H/Le(y)/Le(b) antigens with survival in patients with carcinoma of the lung. N. Engl. J. Med. 327:1992;14.
37. Gabrilovich D.I., Chen H.L., Girgis K.R., Cunningham H.T., Meny G.M., Nadaf S., Kavanaugh D., Carbone D.P. Production of vascular endothelial growth factor by human tumors inhibits the functional maturation of dendritic cells. Nat. Med. 2:1996;1096.
38. Sawano A., Iwai S., Sakurai Y., Ito M., Shitara K., Nakahata T., Shibuya M. Flt-1, vascular endothelial growth factor receptor 1, is a novel cell surface marker for the lineage of monocyte-macrophages in humans. Blood. 97:2001;785.
39. Murata Y., Shimamura T., Hamuro J. The polarization of Th1/Th2 balance is dependent on the intracellular thiol redox status of macrophages due to the distinctive cytokine production. Int. Immunol. 14:2002;201.