Synthesis and Antiproliferative Activity of Basic Ethers of 1,2-Dihydropyrrolo[1,2-a]indole, 6H-Isoindolo[2,1-a]indole, and 6H-Benz[5,6]isoindolo[2,1-a]indole

Oncology Research

Volumn 13, Issue 12, 2002, Pages 537-549

  Guillaumel, Jean ^a   Léonce, Stéphane ^b   Pierré, Alain ^b   Renard, Pierre ^c   Pfeiffer, Bruno ^c   Peruchon, Laure ^a   Arimondo, Paola B ^a   Monneret, Claude ^a  

^a CNRS   (France)

^b INSTITUT DE RECHERCHES SERVIER   (France)

^c INSTITUT DE RECHERCHES INTERNATIONALES SERVIER   (France)

Author keywords

Basic ether; Benz 5,6 isoindolo 2,1 a indole; Cancer; Intercalating agent; Isoindolo 2,1 a indole; Pyrrolo 1,2 a indole; Wittig reaction

Indexed keywords

1,2 DIHYDROPYRROLO[1,2 A]INDOLE DERIVATIVE; 2 [2 (DIETHYLAMINO)ETHOXY] 6H BENZ[5,6]ISOINDOLO[2,1 A ]INDOL 6 ONE; 2 [2 (DIETHYLAMINO)ETHOXY] 6H ISOINDOLO[2,1 A]INDOL 6 ONE; 2,8 BIS[2 (DIETHYLAMINO)ETHOXY] 6H ISOINDOLO[2,1 A]INDOL 6 ONE; 2,9 BIS[2 (DIETHYLAMINO)ETHOXY] 6H ISOINDOLO[2,1 A]INDOL 6 ONE; 6H BENZ[5,6]ISOINDOLO[2,1 A]INDOLE DERIVATIVE; 6H ISOINDOLO[2,1 A]INDOLE DERIVATIVE; 7 [2 (DIETHYLAMINO)ETHOXY] 1,2 DIHYDRO 3H PYRROLO[1,2 A]INDOL 3 ONE; 7,10 BIS[2 (DIETHYLAMINO)ETHOXY] 6H ISOINDOLO[2,1 A]INDOL 6 ONE; 9 [2 (DIETHYLAMINO)ETHOXY] 6H ISOINDOLO[2,1 A]INDOL 6 ONE; DNA; DNA TOPOISOMERASE (ATP HYDROLYSING); ETHER DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BINDING AFFINITY; CANCER CELL CULTURE; CONTROLLED STUDY; CYCLIZATION; CYTOTOXICITY; DRUG ACTIVITY; DRUG DNA BINDING; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; REACTION ANALYSIS; STRUCTURE ACTIVITY RELATION; WITTIG REACTION;

EID: 0842284107     PISSN: 09650407     EISSN: None     Source Type: Journal    
DOI: 10.3727/000000003108748063     Document Type: Article

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