Free Radicals and Diseases in Premature Infants

Antioxidants and Redox Signaling

Volumn 6, Issue 1, 2004, Pages 169-176

  O'Donovan, Donough J ^a,b   Fernandes, Caraciolo J ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b TEXAS CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FREE RADICAL; OXIDIZING AGENT;

BRAIN HEMORRHAGE; HUMAN; LEUKOMALACIA; LUNG DYSPLASIA; NECROTIZING ENTEROCOLITIS; NEWBORN DISEASE; OXIDATIVE STRESS; PATHOGENESIS; PREMATURITY; PRIORITY JOURNAL; RETINOPATHY; REVIEW; TISSUE INJURY;

EID: 0348230940     PISSN: 15230864     EISSN: None     Source Type: Journal    
DOI: 10.1089/152308604771978471     Document Type: Review

References (101)

1. Akisu M, Ozmen D, Baka M, Habif S, Yalaz M, Arslanoglu S, Kultursay N, and Bayindir O. Protective effect of dietary supplementation with L-arginine and L-carnitine on hypoxia/reoxygenation-induced necrotizing enterocolitis in young mice. Biol Neonate 81: 260-265, 2002.
2. Allen RG. Oxygen-reactive species and antioxidant responses during development: the metabolic paradox of cellular differentiation. Proc Soc Exp Biol Med 196: 117-129, 1991.
3. Back SA, Gan X, Li Y, Rosenberg PR, and Volpe JJ. Maturation-dependent vulnerability of oligodendrocytes to oxidative stress-induced death caused by glutathione depletion. J Neurosci 18: 6241-6253, 1998.
4. Benson JW, Drayton MR, Hayward C, Murphy JF, Osborne JP, Rennie JM, Schulte JF, Speidel BD, and Cooke RW. Multicentre trial of ethamsylate for prevention of periventricular haemorrhage in very low birthweight infants. Lancet 2: 1297-1300, 1986.
5. Bongarzone ER, Pasquini JM, and Soto EF. Oxidative damage to proteins and lipids of CNS myelin produced by in vitro generated reactive oxygen species. J Neurosci Res 41: 213-221, 1995.
6. Bougle D, Vert P, Reichart E, Hartemann D, and Heng EL. Retinal superoxide dismutase activity in newborn kittens exposed to normobaric hyperoxia: effect of vitamin E. Pediatr Res 16: 400-402, 1982.
7. Burdon RH. Superoxide and hydrogen peroxide in relation to mammalian cell proliferation. Free Radic Biol Med 18: 775-794, 1995.
8. Burdon RH. Control of cell proliferation by reactive oxygen species. Biochem Soc Trans 24: 1028-1032, 1996.
9. Chen W, Hunt DM, Lu H, and Hunt RC. Expression of antioxidant protective proteins in the rat retina during prenatal and postnatal development. Invest Ophthalmol Vis Sci 40: 744-751, 1999.
10. Chevion M, Berenshtein E, and Stadtman ER. Human studies related to protein oxidation: protein carbonyl content as a marker of damage. Free Radic Res 33 (Suppl): S99-S108, 2000.
11. Connor JR, Pavlick G, Karli D, Menzies SL, and Palmer C. A histochemical study of iron-positive cells in the developing rat brain. J Comp Neurol 355: 111-123, 1995.
12. Cueva JP and Hsueh W. Role of oxygen derived free radicals in platelet activating factor induced bowel necrosis. Gut 29: 1207-1212, 1988.
13. Cunningham S, McColm JR, Wade J, Sedowofia K, McIntosh N, and Fleck B. A novel model of retinopathy of prematurity simulating preterm oxygen variability in the rat. Invest Ophthalmol Vis Sci 41: 4275-4280, 2000.
14. Davis JM, Rosenfeld WN, Sanders RJ, and Gonenne A. Prophylactic effects of recombinant human superoxide dismutase in neonatal lung injury. J Appl Physiol 74: 2234-2241, 1993.
15. Fernandes CJ, Rong L, Tamura T, Stewart KD, Rogers LK, McMicken HW, Elliston JF, Hansen TN, and Smith CV. Stable transfection of Chinese hamster ovary cells with glutamate-cysteine ligase catalytic subunit cDNA confers increased resistance to tert-butyl hydroperoxide toxicity. Toxicol Lett 136: 107-120, 2002.
16. Fowlie PW. Prophylactic intravenous indomethacin for preventing mortality and morbidity in preterm infants. (Cochrane review). In: The Cochrane Library, issue 4. Oxford, U.K.: Update Software, 2002 (software).
17. 2-rich environment: the antioxidant enzymes in the developing rabbit lung. Pediatr Res 18: 240-244, 1984.
18. Frank L and Sosenko IR. Prenatal development of lung antioxidant enzymes in four species. J Pediatr 110: 106-110, 1987.
19. Frank L and Sosenko IR. Failure of premature rabbits to increase antioxidant enzymes during hyperoxic exposure: increased susceptibility to pulmonary oxygen toxicity compared with term rabbits. Pediatr Res 29: 292-296, 1991.
20. Fridovich I. The biology of oxygen radicals. Science 201: 875-880, 1978.
21. Fryer AA, Hume R, and Strange RC. The development of glutathione S-transferase and glutathione peroxidase activities in human lung. Biochim Biophys Acta 883: 448-453, 1986.
22. Garner A. The role of hyperoxia in the aetiology of retinopathy of prematurity. Doc Ophthalmol 74: 187-193, 1990.
23. Gerber CE, Bruchelt G, Stegmann H, Schweinsberg F, and Speer CP. Presence of bleomycin-detectable free iron in the alveolar system of preterm infants. Biochem Biophys Res Commun 257: 218-222, 1999.
24. Gerber CE, Bruchelt G, Gotze-Speer B, and Speer CP. Detection by ELISA of low transferrin levels in bronchoalveolar secretions of preterm infants. J Immunol Methods 233: 41-45, 2000.
25. Granger DN, Rutili G, and McCord JM. Superoxide radicals in feline intestinal ischemia. Gastroenterology 81: 22-29, 1981.
26. Granger DN, Hollwarth ME, and Parks DA. Ischemia-reperfusion injury: role of oxygen-derived free radicals. Acta Physiol Scand 548: 47-63, 1986.
27. Grigg J, Barber A, and Silverman M. Bronchoalveolar lavage fluid glutathione in intubated premature infants. Arch Dis Child 69: 49-51, 1993.
28. Halliwell B. Free radicals, proteins and DNA: oxidative damage versus redox regulation. Biochem Soc Trans 24: 1023-1027, 1996.
29. Halliwell B and Gutteridge JM. Free radicals in biology and medicine, 2nd edit. Oxford: Clarendon Press, 1989.
30. Hardy P, Peri KG, Lahaie I, Varma DR, and Chemtob S. Increased nitric oxide synthesis and action preclude choroidal vasoconstriciton to hyperoxia in newborn pigs. Circ Res 79: 504-511, 1996.
31. Hearse DJ. Ischemia, reperfusion, and the determinants of tissue injury. Cardiovasc Drugs Ther 4: 767-776, 1990.
32. Hearse DJ, Manning AS, Downey JM, and Yellon DM. Xanthine oxidase: a critical mediator of myocardial injury during ischemia and reperfusion? Acta Physiol Scand Suppl 548: 65-78, 1986.
33. Hsueh W, Caplan MS, Qu XW, Tan XD, De Plaen IG, and Gonzalez-Crussi F. Neonatal necrotizing enterocolitis: clinical considerations and pathogenetic concepts. Pediatr Dev Pathol 6: 6-23, 2002.
34. Inder TE, Graham P, Sanderson K, and Taylor BJ. Lipid peroxidation as a measure of oxygen free radical damage in the very low birthweight infant. Arch Dis Child 70: 107-111, 1994.
35. Inder TE, Clemett RS, Austin NC, Graham P, and Darlow BA. High iron status in very low birth weight infants is associated with an increased risk of retinopathy of prematurity. J Pediatr 131: 541-544, 1997.
36. Inder T, Mocatta T, Darlow B, Spencer C, Volpe JJ, and Winterbourn C. Elevated free radical products in the cerebrospinal fluid of VLBW infants with cerebral white matter injury. Pediatr Res 52: 213-218, 2002.
37. Jain A, Mehta T, Auld PA, Rodrigues J, Ward RF, Schwartz MK, and Martensson J. Glutathione metabolism in newborns: evidence for glutathione deficiency in plasma, bronchoalveolar lavage fluid, and lymphocytes in prematures. Pediatr Pulmonol 3: 160-166, 1995.
38. Juarez CP, Muino JC, Guglielmone H, Sambuelli R, Echenique JR, Hemandez M, and Luna JD. Experimental retinopathy of prematurity: angiostatic inhibition by nimodipine, ginkgo-biloba, and dipyridamole, and response to different growth factors. Eur J Ophthalmol 10: 51-59, 2000.
39. Lackmann GM, Hesse L, and Tollner U. Reduced iron-associated antioxidants in premature newborns suffering intracerebral hemorrhage. Free Radic Biol Med 20: 407-409, 1996.
40. Law MR, Wijewardene K, and Wald NJ. Is routine vitamin E administration justified in very low-birthweight infants? Dev Med Child Neurol 2: 442-450, 1990.
41. Lelli JL Jr, Pradhan S, and Cobb LM. Prevention of postischemic injury in immature intestine by deferoxamine. J Surg Res 54: 34-38, 1993.
42. Lindeman JH, Lentjes EG, van Zoeren-Grobben D, and Berger HM. Postnatal changes in plasma ceruloplasmin and transferrin antioxidant activities in preterm babies. Biol Neonate 78: 73-76, 2000.
43. Mates M. Effects of antioxidant enzymes in the molecular control of reactive oxygen species toxicology. Toxicology 153: 83-104, 2000.
44. Mates JM, Perez-Gomez C, and Nunez de Castro I. Antioxidant enzymes and human diseases. Clin Biochem 32: 595-603, 1999.
45. McCord JM. Oxygen-derived free radicals in postischemic tissue injury. N Engl J Med 312: 159-163, 1985.
46. McCord JM and Fridovich I. The biology and pathology of oxygen radicals. Ann Int Med 89: 122-127, 1978.
47. McElroy MC, Postle AD, and Kelly FJ. Catalase, superoxide dismutase and glutathione peroxidase activities of lung and liver during human development. Biochim Biophys Acta 1117: 153-158, 1992.
48. McLeod DS, Brownstein R, and Lutty GA. Vaso-obliteration in the canine model of oxygen-induced retinopathy. Invest Ophthalmol Vis Sci 37: 300-311, 1996.
49. Ment LR, Stewart WB, Duncan CC, and Lambrecht R. Beagle puppy model of intraventricular hemorrhage. J Neurosurg 57: 219-223, 1982.
50. Ment LR, Stewart WB, Scott DT, and Duncan CC. Beagle puppy model of intraventricular hemorrhage: randomized indomethacin prevention trial. Neurology 33: 179-184, 1983.
51. Ment LR, Stewart WB, Duncan CC. Beagle puppy model of intraventricular hemorrhage: ethamsylate studies. Prostaglandins 27: 245-256, 1984.
52. Ment LR, Stewart WB, and Duncan CC. Beagle puppy model of intraventricular hemorrhage. Effect of superoxide dismutase on cerebral blood flow and prostaglandins. J Neurosurg 62: 563-569, 1985.
53. Miller MJ, McNeill H, Mullane KM, Caravella SJ, and Clark DA. SOD prevents damage and attenuates eicosanoid release in a rabbit model of necrotizing enterocolitis. Am J Physiol 255: G556-G565, 1988.
54. Moison RM, Palinckx JJ, Roest M, Houdkamp E, and Berger HM. Induction of lipid peroxidation of pulmonary surfactant by plasma of preterm babies. Lancet 341: 79-82, 1993.
55. Nielsen JC, Naash MI, and Anderson RE. The regional distribution of vitamins E and C in mature and premature human retinas. Invest Ophthalmol Vis Sci 29: 22-26, 1988.
56. Niesman MR, Johnson KA, and Penn JS. Therapeutic effect of liposomal superoxide dismutase in an animal model of retinopathy of prematurity. Neurochem Res 22: 597-605, 1997.
57. Nycyk JA, Drury JA, and Cooke RW. Breath pentane as a marker for lipid peroxidation and adverse outcome in preterm infants. Arch Dis Child Fetal Neonatal Ed 79: F67-F69, 1998.
58. O'Donovan DJ and Fernandes CJ. Mitochondrial glutathione and oxidative stress: implications for pulmonary oxygen toxicity in premature infants. Mol Genet Metab 71: 352-358, 2000.
59. O'Donovan DJ, Katkin JP, Tamura T, Husser R, Xu X, Smith CV, and Welty SE. Gene transfer of mitochondrially targeted glutathione reductase protects H441 cells from t-butyl hydroperoxide-induced oxidant stresses. Am J Respir Cell Mol Biol 20: 256-263, 1999.
60. O'Donovan DJ, Katkin JP, Tamura T, Smith CV, and Welty SE. Attenuation of hyperoxia-induced growth inhibition in H441 cells by gene transfer of mitochondrially targeted glutathione reductase. Am J Respir Cell Mol Biol 22: 732-738, 2000.
61. Ogihara T, Hirano K, Morinobu T, Kim HS, Hiroi M, Ogihara H, and Tamai H. Raised concentrations of aldehyde lipid peroxidation products in premature infants with chronic lung disease. Arch Dis Child Fetal Neonatal Ed 80: F21-F25, 1999.
62. Oka A, Belliveau MJ, Rosenberg PA, and Volpe JJ. Vulnerability of oligodendroglia to glutamate: pharmacology, mechanisms and prevention. J Neurosci 13: 1441-1453, 1993.
63. Okur H, Kucukaydin M, Kose K, Kontas O, Dogam P, and Kazez A. Hypoxia-induced necrotizing enterocolitis in the immature rat: the role of lipid peroxidation and management by vitamin E. J Pediatr Surg 30: 1416-1419, 1995.
64. Oliver PD and Newsome DA. Mitochondrial superoxide dismutase in mature and developing human retinal pigment epithelium. Invest Ophthalmol Vis Sci 33: 1909-1918, 1992.
65. Padmanabhan RV, Gudapaty R, Liener IE, Schwartz BA, and Hoidal JR. Protection against pulmonary oxygen toxicity in rats by the intratracheal administration of liposome-encapsulated superoxide dismutase or catalase. Am Rev Respir Dis 132: 164-167, 1985.
66. Parks DA and Granger DN. Xanthine oxidase: biochemistry, distribution and physiology. Acta Physiol Scand 548: 87-99, 1986.
67. Penn JS. Oxygen-induced retinopathy in the rat: possible contribution of peroxidation reactions. Doc Ophthalmol 74: 179-186, 1990.
68. Penn JS, Thum LA, and Naash MI. Oxygen-induced retinopathy in the rat. Vitamins C and E as potential therapies. Invest Ophthalmol Vis Sci 33: 1836-1845, 1992.
69. Penn JS, Tolman BL, and Bullard LE. Effect of a water-soluble vitamin E analog, trolox C, on retinal vascular development in an animal model of retinopathy of prematurity. Free Radic Biol Med 22: 977-984, 1997.
70. Phylactos AC, Leaf AA, Costeloe K, and Crawford MA. Erythrocyte copper/zinc superoxide dismutase exhibits reduced activity in preterm and low birth weight infants at birth. Acta Paediatr 84: 1421-1425, 1985.
71. Raju TN, Langenberg P, Bhutani V, and Quinn GE. Vitamin E prophylaxis to reduce retinopathy of prematurity: a reappraisal of published trials. J Pediatr 131: 844-850, 1997.
72. Ramsay PL, O'Brian Smith E, Hegemier S, and Welty SE. Early clinical markers for the development of bronchopulmonary dysplasia: soluble E-Selectin and ICAM-1. Pediatrics 102: 927-932, 1998.
73. Rosenfeld WN, Davis JM, Parton L, Richter SE, Price A, Flaster E, and Kassem N. Safety and pharmacokinetics of recombinant human superoxide dismutase administered intratracheally to premature neonates with respiratory distress syndrome. Pediatrics 97: 811-817, 1996.
74. Russell GA and Cooke RW. Randomised controlled trial of allopurinol prophylaxis in very preterm infants. Arch Dis Child Fetal Neonatal Ed 73: F27-F31, 1995.
75. Saugstad OD. Mechanisms of tissue injury by oxygen radicals: implications for neonatal disease. Acta Paediatr 85: 1-4, 1996.
76. Schlenzig JS, Bervoets K, von Loewenich V, and Bohles H. Urinary malondialdehyde concentration in preterm neonates: is there a relationship to disease entities of neonatal intensive care? Acta Paediatr 82: 202-205, 1993.
77. Schock BC, Sweet DG, Halliday HL, Young IS, and Ennis M. Oxidative stress in lavage fluid of preterm infants at risk of chronic lung disease. Am J Physiol Lung Cell Mol Physiol 281: L1386-L1391, 2001.
78. Smith CV, Hansen TN, Martin NE, McMicken HW, and Elliott SJ. Oxidant stress responses in premature infants during exposure to hyperoxia. Pediatr Res 34: 360-365, 1993.
79. Smith LE. Pathogenesis of retinopathy of prematurity. Acta Paediatr Suppl 91: 26-28, 2002.
80. Sohal RS, Allen RG, and Nations C. Oxygen free radicals play a role in cellular differentiation: an hypothesis. J Free Radic Biol Med 2: 175-181, 1986.
81. Strange RC, Cotton W, Fryer AA, Drew R, Bradwell AR, Marshall T, Collins MF, Bell J, and Hume R. Studies on the expression of Cu,Zn superoxide dismutase in human tissues during development. Biochim Biophys Acta 964: 260-265, 1988.
82. Sullivan JL. Iron, plasma antioxidants, and the "oxygen radical disease of prematurity." Am J Dis Child 142: 1341-1344, 1988.
83. Sullivan JL and Newton RB. Serum antioxidant activity in neonates. Arch Dis Child 63: 748-750, 1988.
84. Suresh GK, Davis JM, and Soll RF. Superoxide dismutase for preventing chronic lung disease in mechanically ventilated preterm infants. Cochrane Database Syst Rev (1): CD001968, 2001.
85. The Cryotherapy for Retinopathy of Prematurity Cooperative Group. Multicenter trial of cryotherapy for retinopathy of prematurity: natural history ROP: ocular outcome at 5(1/2) years in premature infants with birth weights less than 1251 g. Arch Ophthalmol 20: 595-599, 2002.
86. Tin W, Milligan DW, Pennefather P, and Hey E. Pulse oximetry, severe retinopathy, and outcome at one year in babies of less than 28 weeks gestation. Arch Dis Child Fetal Neonatal Ed 84: F106-F110, 2001.
87. Turrens JF, Crapo JD, and Freeman BA. Protection against oxygen toxicity by intravenous injection of liposome-entrapped catalase and superoxide dismutase. J Clin Invest 73: 87-95, 1984.
88. Varsila E, Pitkanen O, Hallman M, and Andersson S. Immaturity-dependent free radical activity in premature infants. Pediatr Res 36: 55-59, 1994.
89. Varsila E, Pesonen E, and Andersson S. Early protein oxidation in the neonatal lung is related to development of chronic lung disease. Acta Paediatr 84: 1296-1299, 1995.
90. Vaughan WG, Horton JW, and Walker PB. Allopurinol prevents intestinal permeability changes after ischemia-reperfusion injury. J Pediatr Surg 27: 968-973, 1992.
91. Vilar-Rojas C, Guzman-Grenfell AM, and Hicks JJ. Participation of oxygen-free radicals in the oxido-reduction of proteins. Arch Med Res 27: 1-6, 1996.
92. Vina J, Vento M, Garcia-Sala F, Puertes IR, Gasco E, Sastre J, Aseni M, and Pallardo FV. L-Cysteine and glutathione metabolism are impaired in premature infants due to cystathionase deficiency. Am J Clin Nutr 61: 1067-1069, 1995.
93. Volpe JJ. Neurology of the Newborn, 4th edit. Philadelphia: WB Saunders, 2001.
94. Walther FJ, Gidding CE, Kuipers IM, Willebrand D, Bevers EM, Abuchowski A, and Viau AT. Prevention of oxygen toxicity with superoxide dismutase and catalase in premature lambs. J Free Radic Biol Med 2: 289-293, 1986.
95. Warner BB and Wispé JR. Free radical-mediated diseases in pediatrics. Semin Perinatol 16: 47-57, 1992.
96. Weinberger B, Laskin DL, Heck DE, and Laskin JD. Oxygen toxicity in premature infants. Toxicol Appl Pharmacol 181: 60-67, 2002.
97. Winterbourn CC, Chan T, Buss IH, Inder TE, Mogridge N, and Darlow BA. Protein carbonyls and lipid peroxidation products as oxidation markers in preterm infant plasma: associations with chronic lung disease and retinopathy and effects of selenium supplementation. Pediatr Res 48: 84-90, 2000.
98. Wispe JR and Roberts R J. Molecular basis of pulmonary oxygen toxicity. Clin Perinatol 14: 651-666, 1987.
99. Wispe JR, Bell EF, and Roberts RJ. Assessment of lipid peroxidation in newborn infants and rabbits by measurements of expired ethane and pentane: influence of parenteral lipid infusion. Pediatr Res 19: 374-379, 1985.
100. Wood NS, Marlow N, Costeloe K, and Gibson AT. Neurologic and developmental disability after extremely preterm birth. N Engl J Med 343: 378-384, 2000.
101. Yonezawa M, Back SA, Gan X, Rosenberg PA, and Volpe JJ. Cystine deprivation induces oligodendroglial death: rescue by free radical scavengers and by a diffuse glial factor. J Neurochem 67: 566-573, 1996.