Effect of a water-soluble vitamin E analog, Trolox C, on retinal vascular development in an animal model of retinopathy of prematurity

Free Radical Biology and Medicine

Volumn 22, Issue 6, 1997, Pages 977-984

  Penn, John S ^a   Tolman, Barbara L ^a   Bullard, Lawrence E ^a  

^a UNIVERSITY OF ARKANSAS AT LITTLE ROCK   (United States)

Author keywords

Free radicals; Hyperoxia; Retina; Retinopathy of prematurity; Trolox C; Vasculogenesis

Indexed keywords

ALPHA TOCOPHEROL DERIVATIVE; FREE RADICAL; TROLOX C;

ANGIOGENESIS; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; HYPEROXIA; INTRAPERITONEAL DRUG ADMINISTRATION; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT; RETINA BLOOD VESSEL; RETROLENTAL FIBROPLASIA;

ANIMALS; ANIMALS, NEWBORN; ANTIOXIDANTS; CAPILLARIES; CHROMANS; DEXTRANS; DISEASE MODELS, ANIMAL; FLUORESCEIN; FLUORESCEIN-5-ISOTHIOCYANATE; FLUORESCEINS; HUMANS; INFANT, NEWBORN; INJECTIONS, INTRAPERITONEAL; INK; OXYGEN; RATS; RATS, SPRAGUE-DAWLEY; RETINA; RETINOPATHY OF PREMATURITY;

ANIMALIA;

EID: 0031057620     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(96)00479-0     Document Type: Article

References (42)

1. Valentine P. H., Jackson J. C., Kalina R. E., Woodrum D. E. Increased survival of low birth weight infants: Impact on the incidence of retionpathy of prematurity. Pediatrics. 84:1989;442-445.
2. Owens W. C., Owens E. U. Retrolental fibroplasia in premature infants. II. Studies on the prophylaxis of the disease. The use of alphatocopheryl acetate. Am. J. Ophthalmol. 32:1949;1631-1637.
3. Nielsen J. C., Naash M. I., Anderson E. E. The regional distribution of vitamins E and C in mature and premature human retinas. Invest. Ophthalmol. Vis. Sci. 29:1988;22-29.
4. Flower R. W., Hall M. O., Patz A. Oxygen. Sears M. L. Pharmacology of the eye. 1984;627-638 Springer Verlag, New York.
5. Wu T. W., Hashimoto N., Wu J., Carey D., Li R. K., Mickle D. A. G., Weisel R. D. The cryoprotection effect of Trolox C demonstrated with three types of human cells. Biochem. Cell Biol. 68:1990;1189-1194.
6. Zeng L. H., Wu J., Carey D., Wu T. W. Trolox C and ascorbate: Are they synergistic in protecting liver cells in vitro and in vivo? Biochem. Cell Biol. 69:1991;198-201.
7. Cort W. M., Scott J. W., Araujo M., Mergens W. J., Cannalonga M. A., Osadca M., Harley H. Antioxidant activity and stability of 6-hydroxy-2,5,7,8-Tetramethylchroman-2-Carboxylic Acid. J. Am. Oil Chem. Soc. 52:1975;174-178.
8. Penn J. S., Tolman B. L., Lowery L. A. Variable oxygen exposure causes preretinal neovascularization in the newborn rat. Invest. Ophthalmol. Vis. Sci. 34:1993;576-585.
9. Penn J. S., Tolman B. L., Henry M. M. Oxygen-induced retinopathy in the rat: Relationship of retinal nonperfusion to subsequent neovascularization. Invest Ophthalmol. Vis. Sci. 35:1994;3429-3435.
10. 2 variation determines the severity of oxygen-induced retinopathy in newborn rats. Invest. Ophthalmol. Vis. Sci. 36:1995;2063-2070.
11. Reyaud X., Hansen R. M., Fulton A. B. Effect of prior oxygen exposure on the electroretinographic responses of infant rats. Invest. Ophthalmol. Vis. Sci. 36:1995;2071-2080.
12. Holmes J. M., Duffner L. A. The effect of postnatal growth retardation on abnormal neovascularization in the oxygen exposed neonatal rat. Curr. Eye Res. 15:1996;403-410.
13. Penn J. S., Henry M. M. Evaluation of blood vessel assessment techniques in animals with retinal vascular disease. J. Ophthal. Photogr. 18:1996;26-33.
14. Smith L. E. H., Wesolowski E., McLellan A et al. Oxygen-induced retinopathy in the mouse. Invest. Ophthalmol. Vis. Sci. 35:1994;101-111.
15. Klein H. H., Pich S., Schuff-Werner P., Niedmann P., Blattmann U., Nebendahl K. The effects of Trolox C, a water-soluble vitamin E analogue, in regionally ischemic, reperfused porcine hearts. Int. J. Cardiol. 32:1991;291-301.
16. Ashton N. Some aspects of the comparative pathology of oxygen toxicity in the retina. Br. J. Ophthalmol. 52:1968;505-531.
17. Linsenmeier R. A., Yancey C. M. Effects of hyperoxia on the oxygen distribution in the intact cat retina. Invest. Ophthalmol. Vis. Sci. 30:1989;612-618.
18. Daemen F. J. M. Vertebrate rod outer segment membranes. Biochem. Biophys. Acta. 300:1973;255-288.
19. Delmelle M. Possible implication of photooxidation reactions in retinal photo-damage. Photochem. Photobiol. 29:1979;713.
20. Rodieck R. W. The vertebrate retina. Principles of structure and function. 1973;159 W. H. Freeman and Co, San Francisco, CA.
21. Ashton N., Pedler C. Studies on developing retinal vessels. IV. Reaction of endothelial cells to oxygen. Br. J. Ophthalmol. 46:1962;257-276.
22. Dormandy T. L. Free radical oxidation and antioxidants. Lancet. 1:1978;647-650.
23. Slater T. F., Riley P. A. Free radical damage in retrolental fibroplasia. Lancet. 2:1970;467.
24. 2-rich environment: The antioxidant enzymes in the developing rabbit lung. Pediatr. Res. 18:1984;240-244.
25. Law M. R., Wijewardene K., Wald N. J. Is routine vitamin E administration justified in very low-birthweight infants? Dev. Med. Child Neurol. 32:1990;442-450.
26. Kretzer F. L., Hittner H. M. Initiating events in the development of retinopathy of prematurity. Silverman W. A., Flynn J. T. Retinopathy of prematurity. 1985;121-152 Blackwell Scientific Publ.; Boston, MA.
27. Finer N. N., Schindler R. F., Grant G., Gerry B. H., Peters K. L. Effect of intramuscular vitamin E on frequency and severity of retrolental fibroplasia. A controlled trial. Lancet. 1:1982;1087-1091.
28. Hittner H. M., Kretzer F. L. Efficacy of vitamin E in suppressing the development of severe retinopathy of prematurity. McPherson A. R., Hittner H. M., Kretzer F. L. Retinopathy of prematurity: Current concepts and controversies. 1986;89-103 B.C. Decker, Toronto, Canada.
29. Hittner H. M., Rudolph A. J., Kretzer F. L. Suppression of severe retinopathy of prematurity with vitamin E supplementation: Ultrastructural mechanism of clinical efficacy. Ophthalmology. 91:1984;1512-1521.
30. Terry T. L. Extreme prematurity and fibroblastic overgrowth of persistent vascular sheath behind each crystalline lens: Preliminary report. Am. J. Ophthalmol. 25:1942;203-204.
31. Patz A. Oxygen studies in retrolental fibroplasia IV. Clinical and experimental observations. Am. J. Ophthalmol. 38:1954;291-308.
32. Ashton J., Blach R. Studies in developing retinal vessels VIII. Effect of oxygen on the vessels of the ratling. Br. J. Ophthalmol. 45:1961;321-340.
33. Penn J. S., Gay C. A. Computerized digital image analysis of retinal vessel density: Application to normoxic and hyperoxic rearing of the newborn rat. Exp. Eye Res. 54:1992;329-336.
34. Penn J. S. Oxygen-induced retinopathy in the rat: Possible contribution of peroxidation reactions. Doc. Ophthalmol. 74:1990;179-186.
35. Penn J. S., Thum L. A., Naash M. I. Oxygen-induced retinopathy in the rat. Vitamins C and E as potential therapies. Invest. Ophthalmol. Vis. Sci. 33:1992;1836-1845.
36. Conaway K. J., Niesman M. R., Penn J. S., Tolman B. L., Roberto K. A. Liposome encased superoxide dismutase: Therapeutic value as demonstrated in the rat model of retinopathy of prematurity. Invest. Ophthalmol. Vis. Sci. 36:(4):1995;S69.
37. Yabe H. Effects of vitamin E deficiency on oxygen induced retinopathy in rat. Nippon Ganka Gakkai Zasshi. 89:1985;624-630.
38. Doba T., Burton G. W., Ingold K. U. Antioxidant and coantioxidant activity of vitamin C. The effect of vitamin C, either alone or in the presence of vitamin E or a water-soluble vitamin E analogue, upon the peroxidation of aqueous multilamellar phospholipid liposomes. Biochim. Biophys. Acta. 835:1985;298-303.
39. Suttorp N., Toepfer W., Roka L. Antioxidant defense mechanisms of endothelial cells; Glutathione redox cycle versus catalase. Am. J. Physiol. 251:1986;C671-C680.
40. Mickle D. A. G., Li R. K., Weisel E. R. et al. Myocardial salvage with Trolox C and ascorbic acid for an acute evolving infarction. Ann. Thorac. Surg. 47:1989;553-557.
41. Klein H. H., Nebendahl K., Lindert S., Shrader J., Kruzer H. A modified regionally ischemic porcine heart preparation with eligible residual blood flows. Basic Res. Cardiol. 81:1986;384-393.
42. Rubinstein J. D., Lesnefsky E. J., Byler R. M., Fennessey P. V., Horwitz L. D. Trolox C, a lipid-soluble membrane protective agent, attenuates myocardial injury from ischemia and reperfusion. Free Radic. Biol. Med. 13:1992;627-634.