Role of nitric oxide in renal tubular apoptosis of unilateral ureteral obstruction

Kidney International

Volumn 59, Issue 4, 2001, Pages 1290-1303

  Miyajima, A ^a   Chen, J ^a   Poppas, D P ^a   Vaughan E D , Jr ^a   Felsen, D ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

Cell death; Hemodynamics; Obstructed kidney; Renoprotection; Stretching induced apoptosis

Indexed keywords

CITRULLINE; DNA; LIPOCORTIN 5; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ATROPHY; CELL CULTURE; CELL PROLIFERATION; CELL SIZE; CONTROLLED STUDY; CULTURE MEDIUM; DNA DAMAGE; ENZYME ACTIVITY; FLOW CYTOMETRY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; KIDNEY DISEASE; KIDNEY MASS; KIDNEY TUBULE; KIDNEY TUBULE EPITHELIUM; MECHANICAL STRESS; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; URETER OBSTRUCTION; WESTERN BLOTTING;

EID: 0035072813     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.2001.0590041290.x     Document Type: Article

References (46)

1. The renal hemodynamic response to chronic unilateral complete ureteral occlusion
2. Immunological aspects of acute ureteral obstruction: Immune cell infiltrate in the kidney
3. Pathophysiology of urinary tract obstruction
4. Gene expression in response to acute unilateral ureteral obstruction
5. Cell apoptosis and proliferation in experimental chronic obstructive uropathy
6. Obstructive nephropathy
7. Control of p53 and p21 (WAF1) expression during unilateral ureteral obstruction
8. Antioxidant expression in experimental hydronephrosis: Role of mechanical stretch and growth factors
9. Stretch-mediated release of angiotensin II induces myocyte apoptosis by activating p53 that enhances the local renin-angiotensin system and decreases the Bcl-2-to-Bax protein ratio in the cell
10. Role of the NO system in urinary tract obstruction
11. Activation of endothelium-derived relaxing factor system in acute unilateral ureteral obstruction
12. Nitric oxide generation ameliorates the tubulointerstitial fibrosis of obstructive nephropathy
13. Expression, localization and inhibition of inducible nitric oxide synthase following unilateral ureteral obstruction in rat kidney
14. Location of an inducible nitric oxide synthase mRNA in the normal kidney
15. Nitric oxide and apoptosis: Another paradigm for the double-edged role of nitric oxide
16. Nitric oxide-mediated apoptosis in murine peritoneal macrophages
17. Nitric oxide produced by human B lymphocytes inhibits apoptosis and Epstein-Barr virus reactivation
18. Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase
19. Rapid quantitation of apoptosis in pure and heterogeneous cell populations using flow cytometry
20. A novel assay for apoptosis: Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labeled annexin V
21. Reduced angiotensinogen expression attenuates renal interstitial fibrosis in obstructive nephropathy in mice
22. Nitric oxide synthase expression in cerebral ischemia: Neurochemical, immunocytochemical, and molecular approaches
23. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
24. Experimental insights into the tubulointerstitial disease accompanying primary glomerular lesions
25. Relationship between renal function and histological changes found in renal-biopsy specimens from patients with persistent glomerular nephritis
26. Genesis of renal tubular atrophy in experimental hydronephrosis in the rat: Role of apoptosis
27. Nitric oxide as a bifunctional regulator of apoptosis
28. Interstitial fibrosis of unilateral ureteral obstruction is exacerbated in kidneys of mice lacking the gene for inducible nitric oxide synthase
29. Nitric oxide inhibits Fas-induced apoptosis
30. Hypertension in mice lacking the gene for endothelial nitric oxide synthase
31. Lessons from genetically engineered animal models. IV. Nitric oxide synthase gene knockout mice
32. Mechanical loading regulates NOS expression and activity in developing and adult skeletal muscle
33. Cyclic strain upregulates nitric oxide synthase in cultured bovine aortic endothelial cells
34. Mechanical strain suppresses inducible nitric-oxide synthase in cardiac myocytes
35. Interaction of nitric oxide and transforming growth factor-β-1 induced by angiotensin II and mechanical stretch in rat renal tubular epithelial cells
36. Stretch-induced programmed myocyte cell death
37. Geometric control of cell life and death
38. Mechanotransduction across the cell surface and through the cytoskeleton
39. Obstructive nephropathy in the neonatal rat is attenuated by epidermal growth factor
40. Tubulointerstitial disease in aging: Evidence for underlying peritubular capillary damage, a potential role for renal ischemia
41. Chronic obstructive uropathy in severe combined immunodeficient (SCID) mice: Lymphocyte infiltration is not required for progressive tubulointerstitial injury
42. Splenic B lymphocyte programmed cell death is prevented by nitric oxide release through mechanisms involving sustained Bcl-2 levels
43. Attenuated acute cardiac rejection in NOS2 -/- recipients correlates with reduced apoptosis
44. Exogenous, but not endogenous, nitric oxide increases proliferation rates in senescent human fibroblasts
45. Nitric oxide production contributes to the angiogenic properties of vascular endothelial growth factor in human endothelial cells
46. Dietary supplementation with L-arginine limits cell proliferation in the remnant glomerulus