-
1
-
-
0034886143
-
Toll-like receptors: Critical proteins linking innate and acquired immunity
-
Akira S, Takeda K, Kaisho T (2001) Toll-like receptors: critical proteins linking innate and acquired immunity. Nat Immunol 2:675-680.
-
(2001)
Nat Immunol
, vol.2
, pp. 675-680
-
-
Akira, S.1
Takeda, K.2
Kaisho, T.3
-
2
-
-
0033966411
-
Toll signaling pathways in the innate immune response
-
Anderson KV (2000) Toll signaling pathways in the innate immune response. Curr Opin Immunol 12:13-19.
-
(2000)
Curr Opin Immunol
, vol.12
, pp. 13-19
-
-
Anderson, K.V.1
-
3
-
-
0029125857
-
Aging, energy, and oxidative stress in neurodegenerative diseases
-
Beal MF (1995) Aging, energy, and oxidative stress in neurodegenerative diseases. Ann Neurol 38:357-366.
-
(1995)
Ann Neurol
, vol.38
, pp. 357-366
-
-
Beal, M.F.1
-
4
-
-
0033952703
-
Tlr4: Central component of the sole mammalian LPS sensor
-
Beutler B (2000) Tlr4: central component of the sole mammalian LPS sensor. Curr Opin Immunol 12:20-26.
-
(2000)
Curr Opin Immunol
, vol.12
, pp. 20-26
-
-
Beutler, B.1
-
5
-
-
0035369037
-
A neuron-glia signalling network in the active brain
-
Bezzi P, Volterra A (2001) A neuron-glia signalling network in the active brain. Curr Opin Neurobiol 11:387-394.
-
(2001)
Curr Opin Neurobiol
, vol.11
, pp. 387-394
-
-
Bezzi, P.1
Volterra, A.2
-
6
-
-
0034960228
-
CXCR4-activated astrocyte glutamate release via TNFα: Amplication by microglia triggers neurotoxicity
-
Bezzi P, Domercq M, Brambilla L, Galli R, Schols D, De Clercq E, Vescovi A, Bagetta G, Kollias G, Meldolesi J, Volterra A (2001) CXCR4-activated astrocyte glutamate release via TNFα: amplication by microglia triggers neurotoxicity. Nat Neurosci 4:702-710.
-
(2001)
Nat Neurosci
, vol.4
, pp. 702-710
-
-
Bezzi, P.1
Domercq, M.2
Brambilla, L.3
Galli, R.4
Schols, D.5
De Clercq, E.6
Vescovi, A.7
Bagetta, G.8
Kollias, G.9
Meldolesi, J.10
Volterra, A.11
-
7
-
-
0036455173
-
Intranasal herpes simplex virus type 2 inoculation causes a profound thymidine kinase dependent cerebral inflammatory response in the mouse hindbrain
-
Boivin G, Coulombe Z, Rivest S (2002) Intranasal herpes simplex virus type 2 inoculation causes a profound thymidine kinase dependent cerebral inflammatory response in the mouse hindbrain. Eur J Neurosci 16:29-43.
-
(2002)
Eur J Neurosci
, vol.16
, pp. 29-43
-
-
Boivin, G.1
Coulombe, Z.2
Rivest, S.3
-
8
-
-
0031881687
-
Lipopolysaccharide intranigral injection induces inflammatory reaction and damage in nigrostriatal dopaminergic system
-
Castano A, Herrera AJ, Cano J, Machado A (1998) Lipopolysaccharide intranigral injection induces inflammatory reaction and damage in nigrostriatal dopaminergic system. J Neurochem 70:1584-1592.
-
(1998)
J Neurochem
, vol.70
, pp. 1584-1592
-
-
Castano, A.1
Herrera, A.J.2
Cano, J.3
Machado, A.4
-
9
-
-
0024405528
-
Quantitation of cerebral atrophy in preclinical and end-stage Alzheimer's disease
-
de la Monte SM (1989) Quantitation of cerebral atrophy in preclinical and end-stage Alzheimer's disease. Ann Neurol 25:450-459.
-
(1989)
Ann Neurol
, vol.25
, pp. 450-459
-
-
De La Monte, S.M.1
-
10
-
-
0031897632
-
NF-κB and rel proteins: Evolutionary conserved mediators of immune responses
-
Ghosh S, May MJ, Kopp EB (1998) NF-κB and rel proteins: evolutionary conserved mediators of immune responses. Annu Rev Immunol 16:225-260.
-
(1998)
Annu Rev Immunol
, vol.16
, pp. 225-260
-
-
Ghosh, S.1
May, M.J.2
Kopp, E.B.3
-
11
-
-
0032942060
-
Microglia as mediators of inflammatory and degenerative diseases
-
Gonzales-Scarano F, Baltuch G (1999) Microglia as mediators of inflammatory and degenerative diseases. Annu Rev Neurosci 22:219-240.
-
(1999)
Annu Rev Neurosci
, vol.22
, pp. 219-240
-
-
Gonzales-Scarano, F.1
Baltuch, G.2
-
12
-
-
0035863740
-
Induction of a novel mechanism of accelerated bacterial clearance by lipopolysaccharide in CD14-deficient and Toll-like receptor 4-deficient mice
-
Haziot A, Hijiya N, Gangloff SC, Silver J, Goyert SM (2001) Induction of a novel mechanism of accelerated bacterial clearance by lipopolysaccharide in CD14-deficient and Toll-like receptor 4-deficient mice. J Immunol 166:1075-1078.
-
(2001)
J Immunol
, vol.166
, pp. 1075-1078
-
-
Haziot, A.1
Hijiya, N.2
Gangloff, S.C.3
Silver, J.4
Goyert, S.M.5
-
13
-
-
0031594241
-
NF-kappaB modulates lipopolysaccharide-induced microglial nerve growth factor expression
-
Heese K, Fiebich BL, Bauer J, Otten U (1998) NF-kappaB modulates lipopolysaccharide-induced microglial nerve growth factor expression. Glia 22:401-407.
-
(1998)
Glia
, vol.22
, pp. 401-407
-
-
Heese, K.1
Fiebich, B.L.2
Bauer, J.3
Otten, U.4
-
14
-
-
0034663946
-
Central nervous system-initiated inflammation and neurotrophism in trauma: IL-1 beta is required for the production of ciliary neurotrophic factor
-
Herx LM, Rivest S, Yong VW (2000) Central nervous system-initiated inflammation and neurotrophism in trauma: IL-1 beta is required for the production of ciliary neurotrophic factor. J Immunol 165:2232-2239.
-
(2000)
J Immunol
, vol.165
, pp. 2232-2239
-
-
Herx, L.M.1
Rivest, S.2
Yong, V.W.3
-
15
-
-
0035815545
-
MK-801 is cytotoxic to microglia in vitro and its cytotoxicity is attenuated by glutamate, other excitotoxic agents and atropine. Possible presence of glutamate receptor and muscarinic receptor on microglia
-
Hirayama M, Kuriyama M (2001) MK-801 is cytotoxic to microglia in vitro and its cytotoxicity is attenuated by glutamate, other excitotoxic agents and atropine. Possible presence of glutamate receptor and muscarinic receptor on microglia. Brain Res 897:204-206.
-
(2001)
Brain Res
, vol.897
, pp. 204-206
-
-
Hirayama, M.1
Kuriyama, M.2
-
16
-
-
0035912198
-
Pathways to neuronal injury and apoptosis in HIV-associated dementia
-
Kaul M, Garden GA, Lipton SA (2001) Pathways to neuronal injury and apoptosis in HIV-associated dementia. Nat Neurosci 410:988-994.
-
(2001)
Nat Neurosci
, vol.410
, pp. 988-994
-
-
Kaul, M.1
Garden, G.A.2
Lipton, S.A.3
-
17
-
-
0034663061
-
Regional difference in susceptibility to lipopolysaccharide-induced neurotoxicity in the rat brain: Role of microglia
-
Kim WG, Mohney RP, Wilson B, Jeohn GH, Liu B, Hong JS (2000) Regional difference in susceptibility to lipopolysaccharide-induced neurotoxicity in the rat brain: role of microglia. J Neurosci 20:6309-6316.
-
(2000)
J Neurosci
, vol.20
, pp. 6309-6316
-
-
Kim, W.G.1
Mohney, R.P.2
Wilson, B.3
Jeohn, G.H.4
Liu, B.5
Hong, J.S.6
-
18
-
-
0035170282
-
Toll-like receptor 4: The missing link of the cerebral innate immune response triggered by circulating gram-negative bacterial cell wall components
-
Laflamme N, Rivest S (2001) Toll-like receptor 4: the missing link of the cerebral innate immune response triggered by circulating gram-negative bacterial cell wall components. FASEB J 15:155-163.
-
(2001)
FASEB J
, vol.15
, pp. 155-163
-
-
Laflamme, N.1
Rivest, S.2
-
19
-
-
0033573451
-
An essential role of interleukin-1beta in mediating NF-kappaB activity and COX-2 transcription in cells of the blood-brain barrier in response to a systemic and localized inflammation but not during endotoxemia
-
Laflamme N, Lacroix S, Rivest S (1999) An essential role of interleukin-1beta in mediating NF-kappaB activity and COX-2 transcription in cells of the blood-brain barrier in response to a systemic and localized inflammation but not during endotoxemia. J Neurosci 19:10923-10930.
-
(1999)
J Neurosci
, vol.19
, pp. 10923-10930
-
-
Laflamme, N.1
Lacroix, S.2
Rivest, S.3
-
20
-
-
0028226884
-
Regional and developmental heterogeneity in splicing of the rat brain NMDARI mRNA
-
Laurie DJ, Seeburg PH (1994) Regional and developmental heterogeneity in splicing of the rat brain NMDARI mRNA. J Neurosci 14:3180-3194.
-
(1994)
J Neurosci
, vol.14
, pp. 3180-3194
-
-
Laurie, D.J.1
Seeburg, P.H.2
-
21
-
-
0035313969
-
The link between excitotoxic oligodendroglial death and demyelinating diseases
-
Matute C, Alberdi E, Domercq M, Perez-Cerda F, Perez-Samartin A, Sanchez-Gomez M (2001) The link between excitotoxic oligodendroglial death and demyelinating diseases. Trends Neurosci 24:224-230.
-
(2001)
Trends Neurosci
, vol.24
, pp. 224-230
-
-
Matute, C.1
Alberdi, E.2
Domercq, M.3
Perez-Cerda, F.4
Perez-Samartin, A.5
Sanchez-Gomez, M.6
-
22
-
-
0035363487
-
Local immune regulation in the central nervous system by substance P vs. glutamate
-
McCluskey LP, Lampson LA (2001) Local immune regulation in the central nervous system by substance P vs. glutamate. J Neuroimmunol 116:136-146.
-
(2001)
J Neuroimmunol
, vol.116
, pp. 136-146
-
-
McCluskey, L.P.1
Lampson, L.A.2
-
23
-
-
0037105511
-
Endotoxemia prevents the cerebral inflammatory wave induced by intraparenchymal lipopolysaccharide injection: Role of glucocorticoids and CD14
-
Nadeau S, Rivest S (2002) Endotoxemia prevents the cerebral inflammatory wave induced by intraparenchymal lipopolysaccharide injection: role of glucocorticoids and CD14. J Immunol 169:3370-3381.
-
(2002)
J Immunol
, vol.169
, pp. 3370-3381
-
-
Nadeau, S.1
Rivest, S.2
-
24
-
-
0038722154
-
Glucocorticoids play a fundamental role in protecting the brain during innate immune response
-
Nadeau S, Rivest S (2003) Glucocorticoids play a fundamental role in protecting the brain during innate immune response. J Neurosci 23:5536-5544.
-
(2003)
J Neurosci
, vol.23
, pp. 5536-5544
-
-
Nadeau, S.1
Rivest, S.2
-
25
-
-
0036518997
-
Innate immunity: The missing link in neuroprotection and neurodegeneration?
-
Nguyen MD, Julien JP, Rivest S (2002) Innate immunity: the missing link in neuroprotection and neurodegeneration? Nat Rev Neurosci 3:216-227.
-
(2002)
Nat Rev Neurosci
, vol.3
, pp. 216-227
-
-
Nguyen, M.D.1
Julien, J.P.2
Rivest, S.3
-
26
-
-
0033006151
-
Glutamate release from microglia via glutamate transporter is enhanced by amyloid-beta peptide
-
Noda M, Nakanishi H, Akaike N (1999) Glutamate release from microglia via glutamate transporter is enhanced by amyloid-beta peptide. Neuroscience 92:1465-1474.
-
(1999)
Neuroscience
, vol.92
, pp. 1465-1474
-
-
Noda, M.1
Nakanishi, H.2
Akaike, N.3
-
27
-
-
0034001914
-
AMPA-kainate subtypes of glutamate receptor in rat cerebral microglia
-
Noda M, Nakanishi H, Nabekura J, Akaike N (2000) AMPA-kainate subtypes of glutamate receptor in rat cerebral microglia. J Neurosci 20:251-258.
-
(2000)
J Neurosci
, vol.20
, pp. 251-258
-
-
Noda, M.1
Nakanishi, H.2
Nabekura, J.3
Akaike, N.4
-
28
-
-
0038624442
-
Presenilin-Imutation sensitizes oligodendrocytes to glutamate and amyloid toxicities, and exacerbates white matter damage and memory impairment in mice
-
Pak K, Chan SL, Mattson MP (2003) Presenilin-Imutation sensitizes oligodendrocytes to glutamate and amyloid toxicities, and exacerbates white matter damage and memory impairment in mice. Neuromol Med 3:53-64.
-
(2003)
Neuromol Med
, vol.3
, pp. 53-64
-
-
Pak, K.1
Chan, S.L.2
Mattson, M.P.3
-
29
-
-
0032190264
-
Cyclooxygenase and inflammation in Alzheimer's disease: Experimental approaches and clinical interventions
-
Pasinetti G (1998) Cyclooxygenase and inflammation in Alzheimer's disease: experimental approaches and clinical interventions. J Neurosci Res 54:1-6.
-
(1998)
J Neurosci Res
, vol.54
, pp. 1-6
-
-
Pasinetti, G.1
-
32
-
-
0026743059
-
Macrophage-induced cytotoxicity of N-methyl-D-aspartate receptor positive neurons involves excitatory amino acids rather than oxygen intermediates and cytokines
-
Piani D, Spranger M, Frei K, Schaggner A, Fontana A (1992) Macrophage-induced cytotoxicity of N-methyl-D-aspartate receptor positive neurons involves excitatory amino acids rather than oxygen intermediates and cytokines. Eur J Immunol 22:2429-2436.
-
(1992)
Eur J Immunol
, vol.22
, pp. 2429-2436
-
-
Piani, D.1
Spranger, M.2
Frei, K.3
Schaggner, A.4
Fontana, A.5
-
33
-
-
0032509295
-
Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene
-
Poltorak A, He X, Smirnova I, Liu MY, Van Huffel C, Du X, Birdwell D, Alejos E, Silva M, Galanos C, Freudenberg M, Ricciardi-Castagnoli P, Layton B, Beutler B (1998) Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science 282:2085-2088.
-
(1998)
Science
, vol.282
, pp. 2085-2088
-
-
Poltorak, A.1
He, X.2
Smirnova, I.3
Liu, M.Y.4
Van Huffel, C.5
Du, X.6
Birdwell, D.7
Alejos, E.8
Silva, M.9
Galanos, C.10
Freudenberg, M.11
Ricciardi-Castagnoli, P.12
Layton, B.13
Beutler, B.14
-
34
-
-
18544386562
-
Increased A beta peptides and reduced cholesterol and myelin proteins characterize white matter degeneration in Alzheimer's disease
-
Roher AE, Weiss N, Kokjohn TA, Kuo YM, Kalback W, Anthony J, Watson D, Luehrs DC, Sue L, Walker D, Emmerling M, Goux W, Beach T (2002) Increased A beta peptides and reduced cholesterol and myelin proteins characterize white matter degeneration in Alzheimer's disease. Biochemistry 41:11080-11090.
-
(2002)
Biochemistry
, vol.41
, pp. 11080-11090
-
-
Roher, A.E.1
Weiss, N.2
Kokjohn, T.A.3
Kuo, Y.M.4
Kalback, W.5
Anthony, J.6
Watson, D.7
Luehrs, D.C.8
Sue, L.9
Walker, D.10
Emmerling, M.11
Goux, W.12
Beach, T.13
-
35
-
-
0035348157
-
Astrocytes of the mouse neocortex express functional N-methyl-D-aspartate receptors
-
Schipke CG, Ohlemeyer C, Matyash M, Nolte C, Kettenmann H, Kirchhoff F (2001) Astrocytes of the mouse neocortex express functional N-methyl-D-aspartate receptors. FASEB J 15:1270-1272.
-
(2001)
FASEB J
, vol.15
, pp. 1270-1272
-
-
Schipke, C.G.1
Ohlemeyer, C.2
Matyash, M.3
Nolte, C.4
Kettenmann, H.5
Kirchhoff, F.6
-
36
-
-
0030901162
-
Fluoro-Jade: A novel fluorochrome for the sensitive and reliable histochemical localization of neuronal degeneration
-
Schmued LC, Albertson C, Slikker Jr W (1997) Fluoro-Jade: a novel fluorochrome for the sensitive and reliable histochemical localization of neuronal degeneration. Brain Res 751:37-46.
-
(1997)
Brain Res
, vol.751
, pp. 37-46
-
-
Schmued, L.C.1
Albertson, C.2
Slikker Jr., W.3
-
38
-
-
0042171801
-
Polyamines play a critical role in the control of the innate immune response in the mouse central nervous system
-
Soulet D, Rivest S (2003) Polyamines play a critical role in the control of the innate immune response in the mouse central nervous system. J Cell Biol 162:257-268.
-
(2003)
J Cell Biol
, vol.162
, pp. 257-268
-
-
Soulet, D.1
Rivest, S.2
-
39
-
-
0032937860
-
The role of microglia and macrophages in the pathophysiology of the CNS
-
Stoll G, Jander S (1999) The role of microglia and macrophages in the pathophysiology of the CNS. Prog Neurobiol 58:233-247.
-
(1999)
Prog Neurobiol
, vol.58
, pp. 233-247
-
-
Stoll, G.1
Jander, S.2
-
40
-
-
0029655268
-
Effects of chronic intrahippocampal infusion of lipolysaccharide in the rat
-
Szczepanik AM, Fishkin RJ, Rush DK, Wilmot CA (1996) Effects of chronic intrahippocampal infusion of lipolysaccharide in the rat. Neuroscience 70:57-65.
-
(1996)
Neuroscience
, vol.70
, pp. 57-65
-
-
Szczepanik, A.M.1
Fishkin, R.J.2
Rush, D.K.3
Wilmot, C.A.4
-
41
-
-
0036222241
-
TLR4, but not TLR2, mediates IFN-beta-induced STAT I alpha/ beta-dependent gene expression in macrophages
-
Toshchakov V, Jones BW, Perera PY, Thomas K, Cody MJ, Zhang S, Williams BR, Major J, Hamilton TA, Fenton MJ, Vogel SN (2002) TLR4, but not TLR2, mediates IFN-beta-induced STAT I alpha/beta-dependent gene expression in macrophages. Nat Immunol 3:392-398.
-
(2002)
Nat Immunol
, vol.3
, pp. 392-398
-
-
Toshchakov, V.1
Jones, B.W.2
Perera, P.Y.3
Thomas, K.4
Cody, M.J.5
Zhang, S.6
Williams, B.R.7
Major, J.8
Hamilton, T.A.9
Fenton, M.J.10
Vogel, S.N.11
-
42
-
-
0036467392
-
Toll-like receptors: Key mediators of microbe detection
-
Underhill D, Ozinsky A (2002) Toll-like receptors: key mediators of microbe detection. Curr Opin Immunol 14:103-110.
-
(2002)
Curr Opin Immunol
, vol.14
, pp. 103-110
-
-
Underhill, D.1
Ozinsky, A.2
-
43
-
-
0036499004
-
Heat-shock proteins as activators of the innate immune system
-
Wallin RP, Lundqvist A, More SH, Bonin A, Kiessling R, Ljunggren HG (2002) Heat-shock proteins as activators of the innate immune system. Trends Immunol 23:130-135.
-
(2002)
Trends Immunol
, vol.23
, pp. 130-135
-
-
Wallin, R.P.1
Lundqvist, A.2
More, S.H.3
Bonin, A.4
Kiessling, R.5
Ljunggren, H.G.6
-
44
-
-
0034911054
-
Multiple sclerosis: Altered glutamate homeostasis in lesions correlates with oligodendrocyte and axonal damage
-
Werner P, Pitt D, Raine CS (2001) Multiple sclerosis: altered glutamate homeostasis in lesions correlates with oligodendrocyte and axonal damage. Ann Neurol 50:169-180.
-
(2001)
Ann Neurol
, vol.50
, pp. 169-180
-
-
Werner, P.1
Pitt, D.2
Raine, C.S.3
|