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Volumn 23, Issue 35, 2003, Pages 11094-11103

Modulation of the Innate Immune Response by NMDA Receptors Has Neuropathological Consequences

Author keywords

Demyelination; Glutamate; in situ hybridization histochemistry; Inflammation; Innate immune response; Lipopolysaccharide; Macrophages; Microglia; Proinflammatory cytokines

Indexed keywords

CD14 ANTIGEN; COMPLEMENTARY RNA; CYTOKINE; DIZOCILPINE; ENDOTOXIN; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; GLUTAMIC ACID; MESSENGER RNA; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; RECEPTOR SUBUNIT; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA;

EID: 0348010296     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.23-35-11094.2003     Document Type: Article
Times cited : (34)

References (44)
  • 1
    • 0034886143 scopus 로고    scopus 로고
    • Toll-like receptors: Critical proteins linking innate and acquired immunity
    • Akira S, Takeda K, Kaisho T (2001) Toll-like receptors: critical proteins linking innate and acquired immunity. Nat Immunol 2:675-680.
    • (2001) Nat Immunol , vol.2 , pp. 675-680
    • Akira, S.1    Takeda, K.2    Kaisho, T.3
  • 2
    • 0033966411 scopus 로고    scopus 로고
    • Toll signaling pathways in the innate immune response
    • Anderson KV (2000) Toll signaling pathways in the innate immune response. Curr Opin Immunol 12:13-19.
    • (2000) Curr Opin Immunol , vol.12 , pp. 13-19
    • Anderson, K.V.1
  • 3
    • 0029125857 scopus 로고
    • Aging, energy, and oxidative stress in neurodegenerative diseases
    • Beal MF (1995) Aging, energy, and oxidative stress in neurodegenerative diseases. Ann Neurol 38:357-366.
    • (1995) Ann Neurol , vol.38 , pp. 357-366
    • Beal, M.F.1
  • 4
    • 0033952703 scopus 로고    scopus 로고
    • Tlr4: Central component of the sole mammalian LPS sensor
    • Beutler B (2000) Tlr4: central component of the sole mammalian LPS sensor. Curr Opin Immunol 12:20-26.
    • (2000) Curr Opin Immunol , vol.12 , pp. 20-26
    • Beutler, B.1
  • 5
    • 0035369037 scopus 로고    scopus 로고
    • A neuron-glia signalling network in the active brain
    • Bezzi P, Volterra A (2001) A neuron-glia signalling network in the active brain. Curr Opin Neurobiol 11:387-394.
    • (2001) Curr Opin Neurobiol , vol.11 , pp. 387-394
    • Bezzi, P.1    Volterra, A.2
  • 7
    • 0036455173 scopus 로고    scopus 로고
    • Intranasal herpes simplex virus type 2 inoculation causes a profound thymidine kinase dependent cerebral inflammatory response in the mouse hindbrain
    • Boivin G, Coulombe Z, Rivest S (2002) Intranasal herpes simplex virus type 2 inoculation causes a profound thymidine kinase dependent cerebral inflammatory response in the mouse hindbrain. Eur J Neurosci 16:29-43.
    • (2002) Eur J Neurosci , vol.16 , pp. 29-43
    • Boivin, G.1    Coulombe, Z.2    Rivest, S.3
  • 8
    • 0031881687 scopus 로고    scopus 로고
    • Lipopolysaccharide intranigral injection induces inflammatory reaction and damage in nigrostriatal dopaminergic system
    • Castano A, Herrera AJ, Cano J, Machado A (1998) Lipopolysaccharide intranigral injection induces inflammatory reaction and damage in nigrostriatal dopaminergic system. J Neurochem 70:1584-1592.
    • (1998) J Neurochem , vol.70 , pp. 1584-1592
    • Castano, A.1    Herrera, A.J.2    Cano, J.3    Machado, A.4
  • 9
    • 0024405528 scopus 로고
    • Quantitation of cerebral atrophy in preclinical and end-stage Alzheimer's disease
    • de la Monte SM (1989) Quantitation of cerebral atrophy in preclinical and end-stage Alzheimer's disease. Ann Neurol 25:450-459.
    • (1989) Ann Neurol , vol.25 , pp. 450-459
    • De La Monte, S.M.1
  • 10
    • 0031897632 scopus 로고    scopus 로고
    • NF-κB and rel proteins: Evolutionary conserved mediators of immune responses
    • Ghosh S, May MJ, Kopp EB (1998) NF-κB and rel proteins: evolutionary conserved mediators of immune responses. Annu Rev Immunol 16:225-260.
    • (1998) Annu Rev Immunol , vol.16 , pp. 225-260
    • Ghosh, S.1    May, M.J.2    Kopp, E.B.3
  • 11
    • 0032942060 scopus 로고    scopus 로고
    • Microglia as mediators of inflammatory and degenerative diseases
    • Gonzales-Scarano F, Baltuch G (1999) Microglia as mediators of inflammatory and degenerative diseases. Annu Rev Neurosci 22:219-240.
    • (1999) Annu Rev Neurosci , vol.22 , pp. 219-240
    • Gonzales-Scarano, F.1    Baltuch, G.2
  • 12
    • 0035863740 scopus 로고    scopus 로고
    • Induction of a novel mechanism of accelerated bacterial clearance by lipopolysaccharide in CD14-deficient and Toll-like receptor 4-deficient mice
    • Haziot A, Hijiya N, Gangloff SC, Silver J, Goyert SM (2001) Induction of a novel mechanism of accelerated bacterial clearance by lipopolysaccharide in CD14-deficient and Toll-like receptor 4-deficient mice. J Immunol 166:1075-1078.
    • (2001) J Immunol , vol.166 , pp. 1075-1078
    • Haziot, A.1    Hijiya, N.2    Gangloff, S.C.3    Silver, J.4    Goyert, S.M.5
  • 13
    • 0031594241 scopus 로고    scopus 로고
    • NF-kappaB modulates lipopolysaccharide-induced microglial nerve growth factor expression
    • Heese K, Fiebich BL, Bauer J, Otten U (1998) NF-kappaB modulates lipopolysaccharide-induced microglial nerve growth factor expression. Glia 22:401-407.
    • (1998) Glia , vol.22 , pp. 401-407
    • Heese, K.1    Fiebich, B.L.2    Bauer, J.3    Otten, U.4
  • 14
    • 0034663946 scopus 로고    scopus 로고
    • Central nervous system-initiated inflammation and neurotrophism in trauma: IL-1 beta is required for the production of ciliary neurotrophic factor
    • Herx LM, Rivest S, Yong VW (2000) Central nervous system-initiated inflammation and neurotrophism in trauma: IL-1 beta is required for the production of ciliary neurotrophic factor. J Immunol 165:2232-2239.
    • (2000) J Immunol , vol.165 , pp. 2232-2239
    • Herx, L.M.1    Rivest, S.2    Yong, V.W.3
  • 15
    • 0035815545 scopus 로고    scopus 로고
    • MK-801 is cytotoxic to microglia in vitro and its cytotoxicity is attenuated by glutamate, other excitotoxic agents and atropine. Possible presence of glutamate receptor and muscarinic receptor on microglia
    • Hirayama M, Kuriyama M (2001) MK-801 is cytotoxic to microglia in vitro and its cytotoxicity is attenuated by glutamate, other excitotoxic agents and atropine. Possible presence of glutamate receptor and muscarinic receptor on microglia. Brain Res 897:204-206.
    • (2001) Brain Res , vol.897 , pp. 204-206
    • Hirayama, M.1    Kuriyama, M.2
  • 16
    • 0035912198 scopus 로고    scopus 로고
    • Pathways to neuronal injury and apoptosis in HIV-associated dementia
    • Kaul M, Garden GA, Lipton SA (2001) Pathways to neuronal injury and apoptosis in HIV-associated dementia. Nat Neurosci 410:988-994.
    • (2001) Nat Neurosci , vol.410 , pp. 988-994
    • Kaul, M.1    Garden, G.A.2    Lipton, S.A.3
  • 17
    • 0034663061 scopus 로고    scopus 로고
    • Regional difference in susceptibility to lipopolysaccharide-induced neurotoxicity in the rat brain: Role of microglia
    • Kim WG, Mohney RP, Wilson B, Jeohn GH, Liu B, Hong JS (2000) Regional difference in susceptibility to lipopolysaccharide-induced neurotoxicity in the rat brain: role of microglia. J Neurosci 20:6309-6316.
    • (2000) J Neurosci , vol.20 , pp. 6309-6316
    • Kim, W.G.1    Mohney, R.P.2    Wilson, B.3    Jeohn, G.H.4    Liu, B.5    Hong, J.S.6
  • 18
    • 0035170282 scopus 로고    scopus 로고
    • Toll-like receptor 4: The missing link of the cerebral innate immune response triggered by circulating gram-negative bacterial cell wall components
    • Laflamme N, Rivest S (2001) Toll-like receptor 4: the missing link of the cerebral innate immune response triggered by circulating gram-negative bacterial cell wall components. FASEB J 15:155-163.
    • (2001) FASEB J , vol.15 , pp. 155-163
    • Laflamme, N.1    Rivest, S.2
  • 19
    • 0033573451 scopus 로고    scopus 로고
    • An essential role of interleukin-1beta in mediating NF-kappaB activity and COX-2 transcription in cells of the blood-brain barrier in response to a systemic and localized inflammation but not during endotoxemia
    • Laflamme N, Lacroix S, Rivest S (1999) An essential role of interleukin-1beta in mediating NF-kappaB activity and COX-2 transcription in cells of the blood-brain barrier in response to a systemic and localized inflammation but not during endotoxemia. J Neurosci 19:10923-10930.
    • (1999) J Neurosci , vol.19 , pp. 10923-10930
    • Laflamme, N.1    Lacroix, S.2    Rivest, S.3
  • 20
    • 0028226884 scopus 로고
    • Regional and developmental heterogeneity in splicing of the rat brain NMDARI mRNA
    • Laurie DJ, Seeburg PH (1994) Regional and developmental heterogeneity in splicing of the rat brain NMDARI mRNA. J Neurosci 14:3180-3194.
    • (1994) J Neurosci , vol.14 , pp. 3180-3194
    • Laurie, D.J.1    Seeburg, P.H.2
  • 22
    • 0035363487 scopus 로고    scopus 로고
    • Local immune regulation in the central nervous system by substance P vs. glutamate
    • McCluskey LP, Lampson LA (2001) Local immune regulation in the central nervous system by substance P vs. glutamate. J Neuroimmunol 116:136-146.
    • (2001) J Neuroimmunol , vol.116 , pp. 136-146
    • McCluskey, L.P.1    Lampson, L.A.2
  • 23
    • 0037105511 scopus 로고    scopus 로고
    • Endotoxemia prevents the cerebral inflammatory wave induced by intraparenchymal lipopolysaccharide injection: Role of glucocorticoids and CD14
    • Nadeau S, Rivest S (2002) Endotoxemia prevents the cerebral inflammatory wave induced by intraparenchymal lipopolysaccharide injection: role of glucocorticoids and CD14. J Immunol 169:3370-3381.
    • (2002) J Immunol , vol.169 , pp. 3370-3381
    • Nadeau, S.1    Rivest, S.2
  • 24
    • 0038722154 scopus 로고    scopus 로고
    • Glucocorticoids play a fundamental role in protecting the brain during innate immune response
    • Nadeau S, Rivest S (2003) Glucocorticoids play a fundamental role in protecting the brain during innate immune response. J Neurosci 23:5536-5544.
    • (2003) J Neurosci , vol.23 , pp. 5536-5544
    • Nadeau, S.1    Rivest, S.2
  • 25
    • 0036518997 scopus 로고    scopus 로고
    • Innate immunity: The missing link in neuroprotection and neurodegeneration?
    • Nguyen MD, Julien JP, Rivest S (2002) Innate immunity: the missing link in neuroprotection and neurodegeneration? Nat Rev Neurosci 3:216-227.
    • (2002) Nat Rev Neurosci , vol.3 , pp. 216-227
    • Nguyen, M.D.1    Julien, J.P.2    Rivest, S.3
  • 26
    • 0033006151 scopus 로고    scopus 로고
    • Glutamate release from microglia via glutamate transporter is enhanced by amyloid-beta peptide
    • Noda M, Nakanishi H, Akaike N (1999) Glutamate release from microglia via glutamate transporter is enhanced by amyloid-beta peptide. Neuroscience 92:1465-1474.
    • (1999) Neuroscience , vol.92 , pp. 1465-1474
    • Noda, M.1    Nakanishi, H.2    Akaike, N.3
  • 27
    • 0034001914 scopus 로고    scopus 로고
    • AMPA-kainate subtypes of glutamate receptor in rat cerebral microglia
    • Noda M, Nakanishi H, Nabekura J, Akaike N (2000) AMPA-kainate subtypes of glutamate receptor in rat cerebral microglia. J Neurosci 20:251-258.
    • (2000) J Neurosci , vol.20 , pp. 251-258
    • Noda, M.1    Nakanishi, H.2    Nabekura, J.3    Akaike, N.4
  • 28
    • 0038624442 scopus 로고    scopus 로고
    • Presenilin-Imutation sensitizes oligodendrocytes to glutamate and amyloid toxicities, and exacerbates white matter damage and memory impairment in mice
    • Pak K, Chan SL, Mattson MP (2003) Presenilin-Imutation sensitizes oligodendrocytes to glutamate and amyloid toxicities, and exacerbates white matter damage and memory impairment in mice. Neuromol Med 3:53-64.
    • (2003) Neuromol Med , vol.3 , pp. 53-64
    • Pak, K.1    Chan, S.L.2    Mattson, M.P.3
  • 29
    • 0032190264 scopus 로고    scopus 로고
    • Cyclooxygenase and inflammation in Alzheimer's disease: Experimental approaches and clinical interventions
    • Pasinetti G (1998) Cyclooxygenase and inflammation in Alzheimer's disease: experimental approaches and clinical interventions. J Neurosci Res 54:1-6.
    • (1998) J Neurosci Res , vol.54 , pp. 1-6
    • Pasinetti, G.1
  • 32
    • 0026743059 scopus 로고
    • Macrophage-induced cytotoxicity of N-methyl-D-aspartate receptor positive neurons involves excitatory amino acids rather than oxygen intermediates and cytokines
    • Piani D, Spranger M, Frei K, Schaggner A, Fontana A (1992) Macrophage-induced cytotoxicity of N-methyl-D-aspartate receptor positive neurons involves excitatory amino acids rather than oxygen intermediates and cytokines. Eur J Immunol 22:2429-2436.
    • (1992) Eur J Immunol , vol.22 , pp. 2429-2436
    • Piani, D.1    Spranger, M.2    Frei, K.3    Schaggner, A.4    Fontana, A.5
  • 35
  • 36
    • 0030901162 scopus 로고    scopus 로고
    • Fluoro-Jade: A novel fluorochrome for the sensitive and reliable histochemical localization of neuronal degeneration
    • Schmued LC, Albertson C, Slikker Jr W (1997) Fluoro-Jade: a novel fluorochrome for the sensitive and reliable histochemical localization of neuronal degeneration. Brain Res 751:37-46.
    • (1997) Brain Res , vol.751 , pp. 37-46
    • Schmued, L.C.1    Albertson, C.2    Slikker Jr., W.3
  • 37
  • 38
    • 0042171801 scopus 로고    scopus 로고
    • Polyamines play a critical role in the control of the innate immune response in the mouse central nervous system
    • Soulet D, Rivest S (2003) Polyamines play a critical role in the control of the innate immune response in the mouse central nervous system. J Cell Biol 162:257-268.
    • (2003) J Cell Biol , vol.162 , pp. 257-268
    • Soulet, D.1    Rivest, S.2
  • 39
    • 0032937860 scopus 로고    scopus 로고
    • The role of microglia and macrophages in the pathophysiology of the CNS
    • Stoll G, Jander S (1999) The role of microglia and macrophages in the pathophysiology of the CNS. Prog Neurobiol 58:233-247.
    • (1999) Prog Neurobiol , vol.58 , pp. 233-247
    • Stoll, G.1    Jander, S.2
  • 40
    • 0029655268 scopus 로고    scopus 로고
    • Effects of chronic intrahippocampal infusion of lipolysaccharide in the rat
    • Szczepanik AM, Fishkin RJ, Rush DK, Wilmot CA (1996) Effects of chronic intrahippocampal infusion of lipolysaccharide in the rat. Neuroscience 70:57-65.
    • (1996) Neuroscience , vol.70 , pp. 57-65
    • Szczepanik, A.M.1    Fishkin, R.J.2    Rush, D.K.3    Wilmot, C.A.4
  • 42
    • 0036467392 scopus 로고    scopus 로고
    • Toll-like receptors: Key mediators of microbe detection
    • Underhill D, Ozinsky A (2002) Toll-like receptors: key mediators of microbe detection. Curr Opin Immunol 14:103-110.
    • (2002) Curr Opin Immunol , vol.14 , pp. 103-110
    • Underhill, D.1    Ozinsky, A.2
  • 44
    • 0034911054 scopus 로고    scopus 로고
    • Multiple sclerosis: Altered glutamate homeostasis in lesions correlates with oligodendrocyte and axonal damage
    • Werner P, Pitt D, Raine CS (2001) Multiple sclerosis: altered glutamate homeostasis in lesions correlates with oligodendrocyte and axonal damage. Ann Neurol 50:169-180.
    • (2001) Ann Neurol , vol.50 , pp. 169-180
    • Werner, P.1    Pitt, D.2    Raine, C.S.3


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