Biotransformation of 2-phenylethanol to phenylacetaldehyde in a two-phase fed-batch system

Biochemical Engineering Journal

Volumn 17, Issue 1, 2004, Pages 5-13

  Çelik, Devrim ^a   Bayraktar, Emine ^a   Mehmetoǧlu, Ülkü ^a  

^a ANKARA UNIVERSITY   (Turkey)

Author keywords

2 Phenylethanol; Biotransformation; Fed batch operation; Phenylacetaldehyde; Response surface methodology; Two phase system

Indexed keywords

KINETIC THEORY; MICROORGANISMS; ORGANIC ACIDS; OXIDATION; SUBSTRATES;

BIOTRANSFORMATIONS; TWO PHASE SYSTEMS;

BIOCHEMICAL ENGINEERING;

ACETALDEHYDE; ALCOHOL DEHYDROGENASE; ALDEHYDE DEHYDROGENASE; FLAVORING AGENT; OCTANE; PHENETHYL ALCOHOL; PHENYLACETALDEHYDE; PHENYLACETIC ACID; UNCLASSIFIED DRUG;

ARTICLE; BIOTRANSFORMATION; FED BATCH REACTOR; GAS CHROMATOGRAPHY; GLUCONOBACTER OXYDANS; INHIBITION KINETICS; NONHUMAN; OXIDATION; PRIORITY JOURNAL; RESPONSE SURFACE METHOD; TIME;

GLUCONOBACTER OXYDANS; PAA;

EID: 0347915739     PISSN: 1369703X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1369-703X(03)00119-0     Document Type: Article

References (16)

1. B.M.D. Legoy, H.S. Kim, D. Thomas, Use of alcohol dehydrogenase for flavour aldehyde production, Process Biochem. 20 (1985) 145-148.
2. D. Druaux, G. Mangeot, Bacterial bioconversion of primary aliphatic and aromatic alcohols into acids: Effects of molecular structure and physico-chemical conditions, J. Chem. Technol. Biotechnol. 68 (1997) 214-218.
3. M. Manzoni, F. Molinari, A. Tirelli, F. Aragozzini, Phenylacetaldehyde by acetic acid bacteria oxidation of 2-phenylethanol, Biotechnol. Lett. 15 (4) (1993) 341-346.
4. H. Kapucu, Biotransformation of 2-phenlyethanol to phenylacetaldehyde, Ph.D. Thesis, Ankara University, Ankara, Turkey, 2000.
5. F. Molinari, R. Gandolfi, F. Aragozzini, R. Leon, D.M.F. Prazeres, Biotransformation in two-liquid-phase systems production of phenylacetaldehyde by oxidation of 2-phenylethanol with acetic acid bacteria, Enzyme Microbial. Technol. 25 (1999) 729-735.
6. R. Gandolfi, N. Ferrara, F. Molinari, An easy and efficient method for the production of carboxylic acids aldehydes by microbial oxidation of primary alcohols, Tetrahedron Lett. 42 (2001) 513-514.
7. R. Sen, Response surface optimization of the critical media components for the production of surfactin, J. Chem. Technol. Biotechnol. 68 (1997) 263-270.
8. S.J. Kalil, F. Maugeri, M.I. Rodriques, Response surface analysis and simulation as a tool for bioprocess design and optimization, Process Biochem. 35 (2000) 539-550.
9. M. Vazquez, A.M. Martin, Optimization of Phaffia rhodozyma continuous culture through response surface methodology, Biotechnol. Bioeng. 57 (3) (1998) 314-320.
10. M.S.R.C. Murthy, T. Swaminathan, S.K. Rakshit, Y. Kosugi, Statistical optimization of lipase catalyzed hydrolysis of methyloleate by response surface methodology, Bioprocess Eng. 22 (2000) 35-39.
11. J.K. Rao, C.H. Kim, S.K. Rhee, Statistical optimization of medium for the production of recombinant hirudin from Soccharomyces cerevisiae using response surface methodology, Process Biochem. 35 (2000) 639-647.
12. E. Bayraktar, Response surface optimization of the separation of DL-tryptophan using an emulsion liquid membrane, Process Biochem. 37 (2001) 169-175.
13. J. Garcia, F. Rodriguez, J.A. Revenga, Modelling solubility of solids in supercritical fluids using response surface methodology, J. Chem. Technol. Biotechnol. 75 (2000) 245-251.
14. A.I. Khuri, J.A. Cornell, Responses surfaces: Design and Analysis, Marcel Dekker, New York, 1987.
15. D. Çelik, Biotransformation of 2-phenlyethanol to phenylacetaldehyde in a two-phase system, M.Sc. Thesis, Ankara University, Ankara, Turkey, 2001.
16. I.H. Segel, Enzyme Kinetics, Wiley, New York, 1975, pp. 398-505.