Statistical optimization of medium for the production of recombinant hirudin from Saccharomyces cerevisiae using response surface methodology

Process Biochemistry

Volumn 35, Issue 7, 2000, Pages 639-647

  Rao, K Jagannadha ^a   Kim, Chul Ho ^a   Rhee, Sang Ki ^a  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

Author keywords

Central composite design; Medium optimization; r Hirudin; Saccharomyces cerevisiae

Indexed keywords

AMMONIUM SULFATE; CASAMINO ACID; GALACTOSE; PEPTONE; POTASSIUM DIHYDROGEN PHOSPHATE; RECOMBINANT HIRUDIN;

ARTICLE; BLOOD CLOTTING; CARDIOVASCULAR DISEASE; FERMENTATION; NONHUMAN; PURIFICATION; SACCHAROMYCES CEREVISIAE;

EID: 0033972586     PISSN: 13595113     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0032-9592(99)00129-6     Document Type: Article

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