Recombinant Pru p 3 and natural Pru p 3, a major peach allergen, show equivalent immunologic reactivity: A new tool for the diagnosis of fruit allergy

Journal of Allergy and Clinical Immunology

Volumn 111, Issue 3, 2003, Pages 628-633

  Díaz Perales, Araceli ^a   Sanz, María L ^b   García Casado, Gloria ^a   Sánchez Monge, Rosa ^a   García Selles, Francisco J ^c   Lombardero, Manuel ^d   Polo, Florentino ^d   Gamboa, Pedro M ^e   Barber, Domingo ^d   Salcedo, Gabriel ^a  

^a Electrotechnical Section   (Spain)

^b UNIVERSITY CLINIC OF NAVARRA   (Spain)

^c HOSPITAL UNIVERSITARIO VIRGEN DE LA ARRIXACA   (Spain)

^d ALK ABELLÓ   (Denmark)

^e HOSPITAL DE BASURTO   (Spain)

Author keywords

Basophil activation; Diagnosis; Fruit allergy; Histamine release; IgE binding; Lipid transfer protein; Recombinant allergen; Sulphidoleukotriene production

Indexed keywords

ALLERGEN; CARRIER PROTEIN; HISTAMINE; IMMUNOGLOBULIN E; PEPTIDOLEUKOTRIENE; PROTEIN PRU P 3; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; ARTICLE; BASOPHIL; BLOOD SAMPLING; CIRCULAR DICHROISM; CLINICAL ARTICLE; CONTROLLED STUDY; CROSS REACTION; CYTOKINE PRODUCTION; DIAGNOSTIC VALUE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FOOD ALLERGY; FRUIT; HISTAMINE RELEASE; HUMAN; IMMUNOREACTIVITY; IMMUNOTHERAPY; MALE; PEACH; PICHIA PASTORIS; PLANT; POLLEN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN FOLDING;

EID: 0037341956     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1067/mai.2003.75     Document Type: Article

References (24)

1. Sicherer SH. Clinical implications of cross-reactive food allergens. J Allergy Clin Immunol 2001;108:881-90.
2. Pastorello EA, Incorvaia C, Pravettoni V, Farioli L, Conti A, Vigano G, et al. New allergens in fruits and vegetables. Allergy 1998;53(suppl 46):48-51.
3. Rodriguez J, Crespo FJ, Lopez-Rubio A, Cruz-Bertolo J, Ferrando-Vivas P, Vives R, et al. Clinical cross-reactivity among foods of the Rosaceae family. J Allergy Clin Immunol 2000;106:183-9.
4. Pastorello EA, Ortolani C, Farioli L, Pravettoni V, Ispano M, Borga A, et al. Allergenic cross-reactivity among peach, apricot, plum, and ch7erry in patients with oral allergy syndrome: an in vivo and in vitro study. J Allergy Clin Immunol 1994;94:699-707.
5. Sanchez-Monge R, Lombardero M, Garcia-Selles FJ, Barber D, Salcedo G. Lipid-transfer proteins are relevant allergens in fruit allergy. J Allergy Clin Immunol 1999;103:514-9.
6. Scheurer S, Pastorello EA, Wangorsch A, Kästner M, Haustein D, Vieths S. Recombinant allergens Pru av 1 and Pru av 4 and a newly identified lipid transfer protein in the in vitro diagnosis of cherry allergy. J Allergy Clin Immunol 2001;107:724-31.
7. Lindorff-Larsen K, Winther JR. Surprisingly high stability of barley lipid transfer protein, LTP1, towards denaturant, heat and proteases. FEBS Lett 2001;488:145-8.
8. Asero R, Mistrello G, Roncarolo D, de Vries SC, Gautier MF, Ciurana CLF, et al. Lipid transfer protein: a pan-allergen in plant-derived foods that is highly resistant to pepsin digestión. Int Arch Allergy Immunol 2000;122:20-32.
9. Kader JC. Lipid-transfer proteins in plants. Annu Rev Plant Physiol Plant Mol Biol 1996;47:627-54.
10. Pastorello EA, D'Ambrosio FP, Pravettoni V, Farioli L, Giuffrida G, Monza M, et al. Evidence for a lipid transfer protein as the major allergen of apricot. J Allergy Clin Immunol 2000;105:371-7.
11. Pastorello EA, Farioli L, Pravettoni V, Ispano M, Scibola E, Trambaioli C, et al. The maize major allergen, which is responsible for food-induced allergic reactions, is a lipid transfer protein. J Allergy Clin Immunol 2000;106:744-51.
12. Diaz-Perales A, Lombardero M, Sanchez-Monge R, Garcia-Selles FJ, Pernas M, Fernández-Rivas M, et al. Lipid-transfer proteins as potential plant panallergens: cross-reactivity among proteins of Artemisia pollen, Castanea nut and Rosaceae fruits, with different IgE-binding capacities. Clin Exp Allergy 2000;30:1403-10.
13. Duro G, Colombo MA, Costa V, Izzo R, Porcasi R, Di Fiore G, et al. Isolation and characterization of two cDNA clones coding for isoforms of the Parietaria judaica major allergen Parj 1.0101. Int Arch Allergy Appl Immunol 1997;112:348-55.
14. Garcia-Selles FJ, Diaz-Perales A, Sanchez-Monge R, Alcantara M, Lombardero M, Barber D, et al. Patterns of reactivity to lipid transfer protein of plant foods and Artemisia pollen: an in vivo study. Int Arch Allergy Immunol 2002;128:115-22.
15. Diaz-Perales A, Garcia-Casado G, Sanchez-Monge R, Garcia-Selles FJ, Barber D, Salcedo G. cDNA cloning and heterologous expression of the major allergens from peach and apple belonging to the lipid-transfer protein family. Clin Exp Allergy 2002;32:87-92.
16. Chapman MD, Smith AM, Vailes LD, Arruda LK, Dhanaraj V, Pomes A. Recombinant allergens for diagnosis and therapy of allergic disease. J Allergy Clin Immunol 2000;106:409-18.
17. Lorenz AR, Scheurer S, Hanstein D, Vieths S. Recombinant food allergens. J Chromatogr B 2001;756:255-79.
18. Hiller R, Laffer S, Harwanegg C, Huber M, Schmidt WM, Twardosz A, et al. Microarrayed allergen molecules: diagnostic gatekeepers for allergy treatment. FASEB J 2002;16:414-6.
19. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976;72:248-54.
20. Bohm G, Muhr R, Jaenicke R. Quantitative analysis of protein far UV circular dichroism spectra by neural networks. Protein Eng 1992;5:191-5.
21. Sanz ML, Sanchez G, Gamboa PM, Vila L, Uasuf C, Chazot M, et al. Allergen-induced basophil activation: CD63 cell expression detected by flow cytometry in patients allergic to Dermatophagoides pteronyssinus and Lolium perenne. Clin Exp Allergy 2001;31:1007-13.
22. Siraganian RP. Histamine secretion from mast cells and basophils. Trends Pharmacol Sci 1983;4:432-7.
23. Rosano A, Prieto I, Sanz ML, Oehling A. Reliability of histamine release test in dust mite allergy: influence of the sensitisation degree. J Invest Allergol Clin Immunol 1995;5:289-93.
24. Han GW, Lee JY, Song HK, Min CCK, Moon J, Shin DH, et al. Structural basis of non-specific lipid binding in maize lipid-transfer protein complexes revealed by high-resolution X-ray crystallography. J Mol Biol 2001;308:263-78.