Intragenic allelic loss and promoter hypermethylation of the RIZ1 tumor suppressor gene in parathyroid tumors and pheochromocytomas

Surgery

Volumn 134, Issue 6, 2003, Pages 932-939

  Carling, Tobias ^a   Du, Yong ^b   Fang, Wei ^b   Correa, Pamela ^b   Huang, Shi ^b   Doherty, Gerard M ^b   Skogseid, Britt ^b   Hodin, Richard A ^b   Gimm, Oliver ^b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA;

ADOLESCENT; ADULT; AGED; CHROMOSOME 1P; CONFERENCE PAPER; DNA METHYLATION; FEMALE; GENE LOCUS; GENE LOSS; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; PARATHYROID TUMOR; PHEOCHROMOCYTOMA; PRIORITY JOURNAL; PROMOTER REGION; RIBONUCLEASE PROTECTION ASSAY; RIZ1 GENE; TUMOR SUPPRESSOR GENE;

EID: 0347517693     PISSN: 00396060     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0039-6060(03)00422-7     Document Type: Conference Paper

References (24)

1. Carling T. Molecular pathology of parathyroid tumors. Trends Endocrinol & Metab 2001;12:53-8.
2. Lundgren E, Rastad J, Åkerström G, Ljunghall S. Population-based health screening for primary hyperparathyroidism with serum calcium and parathyroid hormone values in menopausal women. Surgery 1997;121:287-94.
3. Carpten JD RC, Villablanca A, Forsberg L, Presciuttini S, Bailey-Wilson J, Simonds WF, et al. HRPT2, encoding parafibromin, is mutated in hyperparathyroidism-jaw tumor syndrome. Nat Genet. 2002;32:676-80.
4. Cryns VL, Thor A, Xu HJ, et al. Loss of the retinoblastoma tumor-suppressor gene in parathyroid carcinoma. N Engl J Med 1994;330:757-61.
5. Tahara H, Smith A, Gaz R, Cryns V, Arnold A. Genomic localization of novel candidate tumor suppressor gene loci in human parathyroid adenomas. Cancer Res 1996;56: 599-605.
6. Williamson C, Pannett A, Pang J, et al. Localisation of a gene causing endocrine neoplasia to a 4 cM region on chromosome 1p35-p36. J Med Genet 1997;34:617-9.
7. Carling T, Imanishi Y, Gaz R, Arnold A. Analysis of the RAD54 gene on chromosome 1p as a potential tumor-suppressor gene in parathyroid adenomas. Int J Cancer 1999;83:80-2.
8. Imanishi Y, Tahara H. Putative parathyroid tumor suppressor on 1p: independent molecular mechanisms of tumorigenesis from 11q allelic loss. Am J Kidney Dis 2001;38:S165-7.
9. Eng C, Crossey P, Mulligan L, et al. Mutations in the RET proto-oncogene and the von Hippel-Lindau disease tumour suppressor gene in sporadic and syndromic phaeochromocytomas. J Med Genet 1995;32:934-7.
10. Edstöm E, Mahlamäki E, Nord B, et al. Comparative genomic hybridization reveals frequent losses of chromosomes 1p and3q in pheochromocytomas and abdominal paragangliomas, suggesting a common genetic etiology. Am J Pathol 2000;156:651-9.
11. Benn D, Dwight T, Richardson A, et al. Sporadic and familial pheochromocytomas are associated with loss of at least two discrete intervals on chromosome 1p. Cancer Res 2000;60:7048-51.
12. Nikitin A, Juarez-Perez M, Li S, Huang L, Lee W-H. RB-mediated suppression of spontaneous multiple nueroendocrine neoplasia and lung metastasis in Rb +/-mice. Proc Natl Acad Sci USA 1999;96:3916-21.
13. Jiang G, Huang S. The yin-yang of PR-domain family genes in tumorigenesis. Histol Histopathol 2000;15:109-17.
14. Chadwick R, Jiang G, Bennington G, et al. Candidate tumor suppressor RIZ is frequently involved in colorectal carcinogenesis. Proc Natl Acad Sci U S A 2000;97:2662-7.
15. Steele-Perkins G, Fang W, Yang XH, et al. Tumor formation and inactivation of RIZ1, an Rb-binding member of a nuclear protein- methyltransferase superfamily. Genes Dev 2001;15:2250-62.
16. Du V, Carling T, Fang W, Piao Z, Sheu JC, Huang S. Hypermethylation in human cancers of the RIZ1 tumor suppressor gene, a member of a histone/protein methyltransferase superfamily. Cancer Res 2001;61:8094-9.
17. Buyse I, Shao G, Huang S. The retinoblastoma protein binds to RIZ, a zinc-finger protein that shares an epitope with the adenovirus E1A protein. Proc Natl Acad Sci USA 1995;92:4467-71.
18. Carling T, Correa P, Hedberg J, et al. Parathyroid MEN1 gene mutations in relation to clinical characteristics of non-familial primary hyperparathyroidism. J Clin Endocrinol Metab 1998;83:2960-3.
19. Carling T, Åkerström G, Rastad J, Westin G. Vitamin D receptor (VDR) and parathyroid hormone mRNA levels correspond to polymorphic VDR alleles in human parathyroid tumors. J Clin Endocrinol Metab 1998;83:2255-9.
20. Fang W, Piao Z, Simon D, Sheu J, Huang S. Mapping of a minimal deleted region in human hepatocellular carcinoma to 1p36.13-p36.23 and mutational analysis of the RIZ (PRDM2) gene localized to the region. Genes Chromosomes Cancer 2000;28:269-75.
21. Correa P, Juhlin C, Rastad J, Akerstrom G, Westin G, Carling T. Allelic loss in clinically and screening-detected primary hyperparathyroidism. Clin Endocrinol (Oxf) 2002;56:113-7.
22. Buyse I, Takahashi E, Huang S. Physical mapping of the retinoblastoma interacting zinc finger gene RIZ to D1S228 on chromosome 1p36. Genomics 1996;34:119-21.
23. Scwab M, Praml C, Amler L. Genomic instability in 1p and human malignancies. Genes Chrom Cancer 1996;16:211-29.
24. Jensen S, Sulman E, Maris J, et al. An integrated transcript map of human chromosome 1p35-p36. Genomics 1997;42: 126-36.