GATA-6 stimulates a cell line-specific activation element in the human lactase promoter

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 274, Issue 2 37-2, 1998, Pages

  Fitzgerald, Kevin ^a   Bazar, Leonard ^a   Avigan, Mark I ^a  

^a GEORGETOWN UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Caco 2 cells; GATA binding proteins; Intestine; Lactase phlorizin hydrolase; Transcription

Indexed keywords

DNA BINDING PROTEIN; GLYCOSYLCERAMIDASE; LACTASE;

ARTICLE; CELL LINE; CELL SPECIFICITY; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; INTESTINE; PRIORITY JOURNAL; PROMOTER REGION; TRANSACTIVATION;

EID: 0031951707     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.1998.274.2.g314     Document Type: Article

References (22)

1. Arceci, R. J., A. A. J. King, C. M. Simon, S. H. Orkin, and D. B. Wilson. Mouse GATA-4: a retinoic acid-inducible GATA-binding transcription factor expressed in endodermally derived tissues and heart. Mol. Cell. Biol. 13: 2235-2246, 1993.
2. Baker, C. An improved chloramphenicol acetyltransferase expression vector system for mapping transcriptional and post-transcriptional regulatory elements in animal cells. In: Recombinant Systems in Protein Expression, edited by K. K. Alitalo, M. L. Huhtala, J. Knowles, and A. Vaheri. Amsterdam: Elsevier Science, 1990, p. 75-86.
3. Bielinska, M., and D. B. Wilson. Regulation of J6 gene expression by transcription factor GATA-4. Biochem. J. 307: 183-189, 1995.
4. Boll, W., P. Wagner, and N. Mantei. Structure of the chromosomal gene and cDNAs coding for lactase-phlorizin hydrolase in humans with adult type hypolactasia or persistence of lactase. Am. J. Hum. Genet. 48: 889-902, 1991.
5. Boukamel, R., and J. N. Freund. The rat LPH gene 5′ region. Comparative structure with the human gene. DNA Seq. 3: 119-121, 1992.
6. Boukamel, R., and J. N. Freund. The cis-element CE-LPH1 of the rat intestinal lactase gene promoter interacts in vitro with several nuclear factors present in endodermal tissues. FEBS Lett. 353: 108-112, 1994.
7. Bradford, M. M. A rapid sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye binding. Anal. Biochem. 72: 248-254, 1976.
8. Chomczynski, P., and N. Sacchi. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162: 156-159, 1987.
9. Davis, D. L., and J. B. E. Burch. The chicken vitellogenin II gene is flanked by a GATA factor-dependent estrogen response unit. Mol. Endocrinol. 10: 937-944, 1996.
10. Dignam, J. D., P. L. Martin, B. S. Shastry, and R. G. Roeder. Eukaryotic gene transcription with purified components. Methods Enzymol. 101: 582-598, 1983.
11. Gordon, J. I. Intestinal epithelial differentiation: new insights from chimeric and transgenic mice. J. Cell Biol. 108: 1187-1194, 1989.
12. Gregory, R. C., D. J. Taxman, D. Seshasayee, M. H. Kensinger, J. J. Bieker, and D. M. Wojchowski. Functional interaction of GATA-1 with erythroid Kruppel-like factor and Sp1 at defined erythroid promoters. Blood 87: 1793-1801, 1996.
13. Grepin, C., L. Robitaille, T. Antakly, and M. Nemer. Inhibition of transcription factor GATA-4 expression blocks in vitro cardiac muscle differentiation. Mol. Cell. Biol. 15: 4095-4102, 1995.
14. Hauri, H.-P., B. Sander, and H. Naim. Induction of lactase biosynthesis in the human intestinal epithelial cell line Caco-2. Eur. J. Biochem. 219: 539-546, 1994.
15. Jumaire, C., and C. Malo. Caco-2 cells cultured in serum-free medium as a model for the study of enterocytic differentiation in vitro. J. Cell. Physiol. 149: 24-33, 1991
16. Ko, L. J., and J. D. Engel. DNA-binding specificities of the GATA transcription factor family. Mol. Cell. Biol. 13: 4011-4022, 1993.
17. Laverriere, A. C., C. MacNeill, C. Muellers, R. E. Poelmann, J. B. E. Burch, and T. Evans. GATA-4/5/6, a subfamily of three transcription factors transcribed in developing heart and gut. J. Biol. Chem. 269: 23177-23184, 1994.
18. Merika, M., and S. H. Orkin. DNA-binding specificity of GATA family transcription factors. Mol. Cell. Biol. 13: 3999-4010, 1993.
19. Miura, N., K. Iwai, and I. Miyamoto. Immunological characterization of hepatocyte nuclear factor 1 protein: appearance of hepatocyte nuclear factor 1 protein in developing mouse embryos. Eur. J. Cell Biol. 60: 376-382, 1993.
20. Montgomery, R. K., H. A. Buller, E. H. H. M. Rings, J. Dekker, and R. J. Grand. Lactose intolerance and the genetic regulation of intestinal lactase-phlorizin hydrolase. FASEB J. 5: 2824-2832, 1991.
21. Morrisey, E. E., H. S. Ip, M. M. Lu, and M. S. Parmacek. GATA-6: a zinc finger transcription factor that is expressed in multiple cell lineages derived from lateral mesoderm. Dev. Biol. 177: 309-322, 1996.
22. Narita, N., M. Heikinheimo, M. Bielinska, R. A. White, and D. B. Wilson. The gene for transcription factor GATA-6 resides on mouse chromosome 18 and is expressed in myocardium and vascular smooth muscle. Genomics 36: 345-348, 1996.