Identification of variable amino acids in the SRS1 region of CYP6B1 modulating furanocoumarin metabolism

Archives of Biochemistry and Biophysics

Volumn 422, Issue 1, 2004, Pages 31-41

  Pan, Liping ^a   Wen, Zhimou ^a   Baudry, Jerome ^a   Berenbaum, May R ^a   Schuler, Mary A ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

Catalytic site mutagenesis; Furanocoumarin metabolism; Homology modeling; P450s (P450 monooxygenases)

Indexed keywords

ALANINE; AMINO ACID; CYTOCHROME P450; CYTOCHROME P450 CYP 6B1; FUROCOUMARIN; GLUTAMIC ACID; GLUTAMINE; HEME; HYDROGEN; ISOLEUCINE; LEUCINE; MUTANT PROTEIN; UNCLASSIFIED DRUG; UNSPECIFIC MONOOXYGENASE; VALINE;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CATALYSIS; CONTROLLED STUDY; CRYSTALLIZATION; HYDROGEN BOND; INSECT; METABOLISM; MODULATION; MOLECULAR RECOGNITION; MUTATION; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN STRUCTURE; REACTION ANALYSIS; SEQUENCE HOMOLOGY; SUBSTRATE RECOGNITION SITE 1;

INSECTA; PAPILIO POLYXENES;

EID: 0347320642     PISSN: 00039861     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.abb.2003.09.047     Document Type: Article

References (30)

1. Berenbaum M.R. Rosenthal G., Berenbaum M.R. Herbivores: Their Interactions with Secondary Plant Metabolites. vol. 1:1991;221-249 Academic Press, San Diego.
2. Murray R.D.H., Mendez J., Brown S.A. The Natural Coumarins. 1982;John Wiley and Sons, Chichester, UK.
3. Feyereisen R. Annu. Rev. Entomol. 44:1999;507-533.
4. Scott J.G. Insect Biochem. Mol. Biol. 29:1999;757-777.
5. Guengerich F.P. Adv. Pharmacol. 43:1997;7-35.
6. Lin J.H., Lu A.Y.H. Clin. Pharmacokinet. 35:1998;361-390.
7. Maenpaa J., Juvonen R., Raunio H., Rautio A., Pelkonen O. Biochem. Pharmacol. 48:1994;1363-1369.
8. Chen J.-S., Berenbaum M.R., Schuler M.A. Insect Mol. Biol. 11:2002;175-186.
9. Baudry J., Li W., Pan L., Berenbaum M.R., Schuler M.A. Protein Eng. 16:2003;577-587.
10. Cohen M.B., Schuler M.A., Berenbaum M.R. Proc. Natl. Acad. Sci. USA. 89:1992;10920-10924.
11. Hung C.-F., Harrison T.L., Berenbaum M.R., Schuler M.A. Insect Mol. Biol. 4:1995;149-160.
12. Li X., Berenbaum M.R., Schuler M.A. Insect Biochem. Mol. Biol. 30:2000;75-84.
13. Li W., Berenbaum M.R., Schuler M.A. Insect Biochem. Mol. Biol. 31:2001;999-1011.
14. Li X., Berenbaum M.R., Schuler M.A. Insect Biochem. Mol. Biol. 32:2002;311-320.
15. Lindberg R.L.P., Negishi M. Nature. 339:1989;632-634.
16. Negishi M., Uno T., Honkakoski P., Sueyoshi T., Darden T.A., Pedersen L.P. Biochimie. 78:1996;685-694.
17. Hung C.F., Berenbaum M.R., Schuler M.A. Insect Biochem. Mol. Biol. 27:1997;377-385.
18. Li W., Petersen R.A., Berenbaum M.R., Schuler M.A. Insect Mol. Biol. 11:2002;543-551.
19. W. Li, M.R. Berenbaum, M.A. Schuler, 2004 (in preparation).
20. MacKerell A.D. Jr., Bashford D., Bellott M., Dunbrack R.L. Jr., Evanseck J.D., Field M.J., Fischer S., Gao J., Guo H., Ha S.et al. J. Phys. Chem. B. 102:1998;3586-3616.
21. Ma R., Cohen M.B., Berenbaum M.R., Schuler M.A. Arch. Biochem. Biophys. 310:1994;332-340.
22. Bradford M.M. Anal. Biochem. 72:1976;248-252.
23. Omura T., Sato R. J. Biol. Chem. 239:1964;2379-2385.
24. Cohen M.B., Berenbaum M.R., Schuler M.A. J. Chem. Ecol. 15:1989;2347-2355.
25. Jefcoate C.R. Methods Enzymol. 52:1978;258-279.
26. Fisher M.T., Scarlata S.F., Sligar S.G. Arch. Biochem. Biophys. 240:1985;456-463.
27. Gotoh O. J. Biol. Chem. 267:1992;83-90.
28. Schenkman J.B., Sligar S.G., Cinti D.L. Pharmacol. Ther. 12:1981;43-71.
29. Loew G.H., Harris D.L. Chem. Rev. 100:2000;407-419.
30. Contzen J., Jung C. Biochemistry. 37:1998;4317-4324.