Characterization of human urinary bladder KATP channels containing SUR2B splice variants expressed in L-cells

European Journal of Pharmacology

Volumn 483, Issue 2-3, 2004, Pages 195-205

  Scott, Victoria E ^a   Davis Taber, Rachel A ^a   Silvia, Christopher ^b   Hoogenboom, Lisa ^a   Choi, Won ^a   Kroeger, Paul ^a   Whiteaker, Kristi L ^a   Gopalakrishnan, Murali ^a  

^a ABBOTT LABORATORIES   (United States)

^b Icagen   (United States)

Author keywords

Cell line; KATP channel; K+ channel opener; Stable; SUR2B; Urinary bladder; 125I A 312110

Indexed keywords

2 CYANO 1 (1,1 DIMETHYLPROPYL) 3 (3 PYRIDYL)GUANIDINE; A 151892; A 312110; ADENOSINE TRIPHOSPHATE; BARBITURIC ACID DERIVATIVE; BAY X 9228; BIS(1,3 DIBUTYLBARBITURIC ACID)TRIMETHINE OXONOL; CROMAKALIM; MESSENGER RNA; N (2 ETHOXYPHENYL) N' (1,2,3 TRIMETHYLPROPYL) 2 NITROETHENE 1,1 DIAMINE; N (4 BENZOYLPHENYL) 3,3,3 TRIFLUORO 2 HYDROXY 2 METHYLPROPIONAMIDE; N [2 (2,2,2 TRIFLUORO 1 HYDROXY 1 TRIFLUOROMETHYLETHYL)NAPHTHALEN 1 YL]; PINACIDIL; POTASSIUM CHANNEL; POTASSIUM CHANNEL STIMULATING AGENT; RECEPTOR SUBUNIT; SULFONYLUREA RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BLADDER; CELL LINE; CORRELATION ANALYSIS; DRUG POTENCY; EXON; FLUORESCENCE; GUINEA PIG; HUMAN; HUMAN CELL; L CELL; MEMBRANE POTENTIAL; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA SPLICING;

EID: 0347318096     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2003.10.034     Document Type: Article

References (32)

1. ATP channels. Physiol. Rev. 78:1998;227-245.
2. Ashcroft S.J., Ashcroft F.M. Properties and functions of ATP-sensitive K-channels. Cell Signal. 2:1990;197-214.
3. ATP channels. Science. 282:1998;1141-1144.
4. + channels in the pig and human detrusor. Eur. J. Pharmacol. 400:2000;287-295.
5. 50) of an enzymatic reaction. Biochem. Pharmacol. 22:1973;3099-3108.
6. ATP channels. Diabetes. 45:1996;1439-1445.
7. + channel. J. Biol. Chem. 274:1999;13656-13665.
8. ATP channel subunits. Neuron. 18:1997;827-838.
9. + channel modulators: update from a decade of progress. J. Med. Chem. 44:2001;1627-1653.
10. ATP channels. Gene. 256:2000;261-270.
11. + channel opener: characterization and pharmacology of binding. Mol. Pharmacol. 64:2003;143-153.
12. 3- and by nonhydrolyzable derivatives of both ATP and ADP. J. Membr. Biol. 104:1988;165-177.
13. ATP) expressed in guinea pig bladder smooth muscle cells. J. Pharmacol. Exp. Ther. 289:1999;551-558.
14. IR 6. 2 combination expressed in HEK-293 cells. Br. J. Pharmacol. 129:2000;1323-1332.
15. Gros L., Trapp S., Dabrowski M., Ashcroft F.M., Bataille D., Blache P. Characterization of two novel forms of the rat sulphonylurea receptor SUR1A2 and SUR1BDelta31. Br. J. Pharmacol. 137:2002;98-106.
16. + channel modulator binding to sulfonylurea receptors SUR2A and SUR2B: opposite effects of MgADP. Mol. Pharmacol. 55:1999;832-840.
17. Hambrock A., Preisig-Muller R., Russ U., Piehl A., Hanley P.J., Ray J., Daut J., Quast U., Derst C. Four novel splice variants of sulfonylurea receptor 1. Am. J. Physiol., Cell Physiol. 283:2002;C587-C598.
18. + channels. Neuron. 16:1996;1011-1017.
19. + channel. J. Biol. Chem. 271:1996;24321-24324.
20. + channels in rat pancreatic β cells modulated by ADP. FEBS Lett. 208:1986;63-66.
21. + channels in isolated membrane patches. J. Physiol. 419:1989;193-211.
22. ATP channel modulators in rat cardiac membranes. Br. J. Pharmacol. 123:1998;1395-1402.
23. + channel in rat pancreatic β cells. Proc. Natl. Acad. Sci. U. S. A. 83:1986;7119-7123.
24. + channel expressed in a mammalian cell line, HEK293T cells. Pflugers. Arch. 435:1998;595-603.
25. + channels in smooth muscle. Physiol. Rev. 77:1997;1165-1231.
26. ATP channel conferred by a novel splice variant of SUR1. J. Physiol. 521:1999;337-350.
27. + channel openers require ATP to bind to and act through sulfonylurea receptors. EMBO J. 17:1998;5529-5535.
28. ATP channels. J. Gen. Physiol. 116:2000;599-608.
29. + channel by 8-azido-ATP. J. Biol. Chem. 274:1999;3931-3933.
30. + channels in the absence of the sulphonylurea receptor. Nature. 387:1997;179-183.
31. Turner S.C., Carroll W.A., White T.K., Brune M.E., Buckner S.A., Gopalakrishnan M., Fabiyi A., Coghlan M.J., Scott V.E., Castle N.A., Daza A.V., Milicic I., Sullivan J.P. Structure-activity relationship of a novel class of naphthyl amide K(ATP) channel openers. Bioorg. Med. Chem. Lett. 13:2003;1741-1744.
32. + channels in hypoxia-induced generalized seizure. Science. 292:2001;1543-1546.